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Found 14 of ic50 for UniProtKB: P29972
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50166561(CHEMBL195380 | Naphthalene-1-sulfonic acid {4-[(4-...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human AQP1 water channel expressed in CHO cells incubated for 10 mins by FLIPR Tetra assayMore data for this Ligand-Target Pair
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TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50089038(CGP 71683 | CGP-71683A | CHEMBL17645 | N-{[(1r,4r)...)
Affinity DataIC50:  2.70E+3nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50354083(CHEMBL1836102 | N-{[(1r,4r)-4-{[(4-aminoquinazolin...)
Affinity DataIC50:  3.90E+3nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50607942(CHEMBL5280011)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of human AQP1 water channel expressed in CHO cells incubated for 10 mins by FLIPR Tetra assayMore data for this Ligand-Target Pair
Ligand Info
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TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178091(5-chloro-N-{[(1r,4r)-4-{[(4-aminoquinazolin-2-yl)a...)
Affinity DataIC50:  5.80E+3nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178092({[7-(2,4-dichlorophenyl)-5-fluoro-2,3-dihydro-1-be...)
Affinity DataIC50:  9.80E+3nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178092({[7-(2,4-dichlorophenyl)-5-fluoro-2,3-dihydro-1-be...)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of human AQP1 water channel expressed in CHO cells incubated for 10 mins by FLIPR Tetra assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178093([7-(2,4-dichlorophenyl)-5-fluoro-2,3-dihydro-1-ben...)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of human AQP1 water channel expressed in CHO cells incubated for 10 mins by FLIPR Tetra assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178093([7-(2,4-dichlorophenyl)-5-fluoro-2,3-dihydro-1-ben...)
Affinity DataIC50:  1.52E+4nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50607939(CHEMBL1537920)
Affinity DataIC50:  1.75E+4nMAssay Description:Inhibition of human AQP1 water channel expressed in Xenopus laevis oocytes assessed as inhibition of AQP1-mediated osmotic swelling incubated for 1 t...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50607938(CHEMBL5280895)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human AQP1 water channel expressed in Xenopus laevis oocytes assessed as inhibition of AQP1-mediated osmotic swelling incubated for 1 t...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178094({[7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-be...)
Affinity DataIC50:  2.94E+4nMAssay Description:Inhibition of human AQP1 water channel expressed in CHO cells incubated for 10 mins by FLIPR Tetra assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178094({[7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-be...)
Affinity DataIC50:  2.94E+4nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50607940(CHEMBL5282904)
Affinity DataIC50:  1.70E+7nMAssay Description:Inhibition of human AQP1 water channel expressed in Xenopus laevis oocytes assessed as inhibition of AQP1-mediated osmotic swelling incubated for 1 t...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed