Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50028449
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278098(CHEMBL520788 | N-((S)-1-amino-3-(2-(trifluoromethy...)
Affinity DataKi:  0.0500nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278837(CHEMBL496690 | N-((S)-1-amino-3-(4-fluorophenyl)pr...)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278099(CHEMBL482536 | N-((S)-1-amino-3-(3-(trifluoromethy...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278833(CHEMBL498051 | N-((S)-1-amino-3-(pyridin-4-yl)prop...)
Affinity DataKi:  2nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278770(CHEMBL470597 | N-((S)-1-amino-3-phenylpropan-2-yl)...)
Affinity DataIC50:  1nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278771(CHEMBL470598 | N-((S)-1-amino-3-cyclohexylpropan-2...)
Affinity DataIC50:  1nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278693((+/-)-N-(1-amino-3-phenylpropan-2-yl)-4-bromo-5-(1...)
Affinity DataIC50:  1nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278836(CHEMBL523586 | N-((S)-1-amino-3-(3-fluorophenyl)pr...)
Affinity DataIC50:  1nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278835(CHEMBL498052 | N-((S)-1-amino-3-(2-fluorophenyl)pr...)
Affinity DataIC50:  1nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278100(CHEMBL482537 | N-((S)-1-amino-3-(4-(trifluoromethy...)
Affinity DataIC50:  2nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278694(4-bromo-N-(1-(methylamino)-3-phenylpropan-2-yl)-5-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278834(CHEMBL524998 | N-((S)-1-amino-3-(4-methoxyphenyl)p...)
Affinity DataIC50:  3nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278568(CHEMBL512480 | N-(5-(1H-pyrrolo[2,3-b]pyridin-4-yl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278648(4-bromo-N-(2-(methylamino)-1-phenylethyl)-5-(1H-py...)
Affinity DataIC50:  3nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278767(4-bromo-N-(1-(ethylamino)-3-phenylpropan-2-yl)-5-(...)
Affinity DataIC50:  4nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278605(CHEMBL512858 | N-(2-amino-1-phenylethyl)-4-cyclopr...)
Affinity DataIC50:  6nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278532(CHEMBL471034 | N-(2-amino-1-phenylethyl)-5-(1H-pyr...)
Affinity DataIC50:  6nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278604(CHEMBL469781 | N-(2-amino-1-phenylethyl)-4-methyl-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278603((+/-)-N-(2-amino-1-phenylethyl)-4-bromo-5-(1H-pyrr...)
Affinity DataIC50:  8nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278691(CHEMBL469802 | N-(3-amino-1-phenylpropyl)-4-bromo-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278768(4-bromo-N-(1-(isopropylamino)-3-phenylpropan-2-yl)...)
Affinity DataIC50:  10nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278533(CHEMBL470192 | N-(2-amino-1-phenylethyl)-5-(1H-pyr...)
Affinity DataIC50:  16nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278690(4-bromo-N-(2-(dimethylamino)-1-phenylethyl)-5-(1H-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278692(CHEMBL513019 | N-(4-amino-1-phenylbutyl)-4-bromo-5...)
Affinity DataIC50:  20nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278565(CHEMBL512305 | N-(2-amino-1-phenylethyl)-4-(1H-pyr...)
Affinity DataIC50:  25nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278569(3-amino-N-(4-bromo-5-(1H-pyrrolo[2,3-b]pyridin-4-y...)
Affinity DataIC50:  25nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278769(CHEMBL513728 | N-((R)-1-amino-3-phenylpropan-2-yl)...)
Affinity DataIC50:  32nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278647(CHEMBL512148 | N-(2-amino-2-phenylethyl)-4-bromo-5...)
Affinity DataIC50:  40nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278534(CHEMBL512672 | N-(2-amino-1-phenylethyl)-4-(1H-pyr...)
Affinity DataIC50:  40nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278606(CHEMBL470200 | N-(2-amino-1-phenylethyl)-4-phenyl-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278645(CHEMBL470202 | N-(2-amino-1-phenylethyl)-4-(1H-pyr...)
Affinity DataIC50:  63nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278644(CHEMBL469357 | N-(2-amino-1-phenylethyl)-4-(pyridi...)
Affinity DataIC50:  63nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278566(CHEMBL469560 | N1-((5-(1H-pyrrolo[2,3-b]pyridin-4-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278646(CHEMBL470409 | N-(2-aminoethyl)-4-bromo-5-(1H-pyrr...)
Affinity DataIC50:  158nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278567(CHEMBL469561 | N1-(5-(1H-pyrrolo[2,3-b]pyridin-4-y...)
Affinity DataIC50:  250nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed