BindingDB PrimarySearch_ki

Found 102 Enz. Inhib. hit(s) with all data for entry = 50009240

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)

IC50: 1.60nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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3D Structure (crystal)

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)

IC50: 2.10nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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CHEMBL DrugBank MCE
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Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)

IC50: 4.30nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526450(CHEMBL4454392)

IC50: 6.5nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526452(CHEMBL4557416)

IC50: 7.20nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526471(CHEMBL4590390)

IC50: 8nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526461(CHEMBL4561431)

IC50: 9.70nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526468(CHEMBL4442778)

IC50: 12nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526451(CHEMBL4460560)

IC50: 13nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526470(CHEMBL4457338)

IC50: 15nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526446(CHEMBL4517080)

IC50: 21nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526475(CHEMBL4554776)

IC50: 22nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526456(CHEMBL4582632)

IC50: 34nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526451(CHEMBL4460560)

IC50: 41nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526447(CHEMBL4564903)

IC50: 45nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526469(CHEMBL4454783)

IC50: 57nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526454(CHEMBL4584510)

IC50: 62nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526461(CHEMBL4561431)

IC50: 70nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526446(CHEMBL4517080)

IC50: 72nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526466(CHEMBL4589134)

IC50: 73nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526454(CHEMBL4584510)

IC50: 81nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526455(CHEMBL4459635)

IC50: 82nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526475(CHEMBL4554776)

IC50: 82nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526453(CHEMBL4577281)

IC50: 90nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526455(CHEMBL4459635)

IC50: 90nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526456(CHEMBL4582632)

IC50: 94nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526461(CHEMBL4561431)

IC50: 96nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526468(CHEMBL4442778)

IC50: 98nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526463(CHEMBL4455024)

IC50: 102nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526453(CHEMBL4577281)

IC50: 103nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526452(CHEMBL4557416)

IC50: 104nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526465(CHEMBL4437650)

IC50: 109nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526454(CHEMBL4584510)

IC50: 140nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526474(CHEMBL4576447)

IC50: 160nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526456(CHEMBL4582632)

IC50: 168nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526452(CHEMBL4557416)

IC50: 172nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526465(CHEMBL4437650)

IC50: 182nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526453(CHEMBL4577281)

IC50: 190nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526462(CHEMBL4465262)

IC50: 194nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 catalytic domain (809 to 1153+9 residues) expressed in baculovirus expression system using TK-biotin ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526468(CHEMBL4442778)

IC50: 215nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526450(CHEMBL4454392)

IC50: 240nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526466(CHEMBL4589134)

IC50: 245nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526466(CHEMBL4589134)

IC50: 254nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526447(CHEMBL4564903)

IC50: 260nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526473(CHEMBL4442811)

IC50: 267nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526471(CHEMBL4590390)

IC50: 287nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526471(CHEMBL4590390)

IC50: 319nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526449(CHEMBL4439150)

IC50: 336nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526451(CHEMBL4460560)

IC50: 361nMAssay Description:Inhibition of recombinant human GST-tagged JAK1 catalytic domain (866 to 1154 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL

PNG

BDBM50526470(CHEMBL4457338)

IC50: 364nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using TK-biotin as...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

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