Compile Data Set for Download or QSAR
maximum 50k data
Found 54 Enz. Inhib. hit(s) with all data for entry = 50017210
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600312(CHEMBL5189266)
Affinity DataIC50:  1nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234969(US9556148, 40 | n-(cyanomethyl)-4-(5-methyl-2-((4-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600312(CHEMBL5189266)
Affinity DataIC50:  3nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234969(US9556148, 40 | n-(cyanomethyl)-4-(5-methyl-2-((4-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234957(4-(2-((4-(4-(1-oxa-8-azaspiro[4.5]decan-8-yl)piper...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234968(4-(2-((4-(4-(6-acetyl-3,6-diazabicyclo[3.1.1]hepta...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234957(4-(2-((4-(4-(1-oxa-8-azaspiro[4.5]decan-8-yl)piper...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234959(US9556148, 27 | n-(cyanomethyl)-4-(2-((4-(4-(tetra...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234973(US9556148, 44 | n-(cyanomethyl)-4-(5-fluoro-2-((4-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234960(US9556148, 28 | n-(cyanomethyl)-4-(2-((4-(4-(2-oxo...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234946(US9556148, 3 | n-(cyanomethyl)-4-(2-((4-(4-morphol...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234973(US9556148, 44 | n-(cyanomethyl)-4-(5-fluoro-2-((4-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234958(US9556148, 25 | n-(cyanomethyl)-4-(2-((4-(4-(5-met...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234954(4-(2-((4-(4-(6-oxa-3-azabicyclo[3.1.1]heptan-3-yl)...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234968(4-(2-((4-(4-(6-acetyl-3,6-diazabicyclo[3.1.1]hepta...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600312(CHEMBL5189266)
Affinity DataIC50:  9nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600306(CHEMBL5201856)
Affinity DataIC50:  10nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234959(US9556148, 27 | n-(cyanomethyl)-4-(2-((4-(4-(tetra...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234960(US9556148, 28 | n-(cyanomethyl)-4-(2-((4-(4-(2-oxo...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234958(US9556148, 25 | n-(cyanomethyl)-4-(2-((4-(4-(5-met...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234946(US9556148, 3 | n-(cyanomethyl)-4-(2-((4-(4-morphol...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234969(US9556148, 40 | n-(cyanomethyl)-4-(5-methyl-2-((4-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234954(4-(2-((4-(4-(6-oxa-3-azabicyclo[3.1.1]heptan-3-yl)...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234973(US9556148, 44 | n-(cyanomethyl)-4-(5-fluoro-2-((4-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234948(4-(2-((4-(4-(1h-1,2,4-triazol-1-yl)piperidin-1-yl)...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600308(CHEMBL5174885)
Affinity DataIC50:  18nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234948(4-(2-((4-(4-(1h-1,2,4-triazol-1-yl)piperidin-1-yl)...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600308(CHEMBL5174885)
Affinity DataIC50:  22nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600306(CHEMBL5201856)
Affinity DataIC50:  35nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234957(4-(2-((4-(4-(1-oxa-8-azaspiro[4.5]decan-8-yl)piper...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234958(US9556148, 25 | n-(cyanomethyl)-4-(2-((4-(4-(5-met...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234959(US9556148, 27 | n-(cyanomethyl)-4-(2-((4-(4-(tetra...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234968(4-(2-((4-(4-(6-acetyl-3,6-diazabicyclo[3.1.1]hepta...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600307(CHEMBL5185244)
Affinity DataIC50:  52nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234960(US9556148, 28 | n-(cyanomethyl)-4-(2-((4-(4-(2-oxo...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600307(CHEMBL5185244)
Affinity DataIC50:  57nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234946(US9556148, 3 | n-(cyanomethyl)-4-(2-((4-(4-morphol...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234948(4-(2-((4-(4-(1h-1,2,4-triazol-1-yl)piperidin-1-yl)...)
Affinity DataIC50:  66nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM234954(4-(2-((4-(4-(6-oxa-3-azabicyclo[3.1.1]heptan-3-yl)...)
Affinity DataIC50:  69nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600307(CHEMBL5185244)
Affinity DataIC50:  97nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600308(CHEMBL5174885)
Affinity DataIC50:  102nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600306(CHEMBL5201856)
Affinity DataIC50:  125nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)
Affinity DataIC50:  134nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600311(CHEMBL5171066)
Affinity DataIC50: >500nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600309(CHEMBL5198976)
Affinity DataIC50: >500nMAssay Description:Inhibition of human JAK2 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600309(CHEMBL5198976)
Affinity DataIC50: >500nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600311(CHEMBL5171066)
Affinity DataIC50: >500nMAssay Description:Inhibition of human JAK1 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50600310(CHEMBL5175767)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human JAK3 kinase domainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Displayed 1 to 50 (of 54 total ) | Next | Last >>
Jump to: