Compile Data Set for Download or QSAR
maximum 50k data
Found 72 Enz. Inhib. hit(s) with all data for entry = 6255
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119725(US8680132, MI- 519- 6401 | US9079913, MI-519-6401)
Affinity DataIC50:  5.60nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119736(US8680132, C09101 | US9079913, C091)
Affinity DataIC50:  8nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119726(US8680132, MI- 77301 (TFA salt) | US8680132, MI- 7...)
Affinity DataIC50:  8.20nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119743(US8680132, C09701)
Affinity DataIC50:  11nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119737(US8680132, C09601 | US9079913, C096)
Affinity DataIC50:  12nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119726(US8680132, MI- 77301 (TFA salt) | US8680132, MI- 7...)
Affinity DataIC50:  13.3nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119732(US8680132, C03401 | US9079913, C03401)
Affinity DataIC50:  18nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119741(US8680132, MI- 710601 | US9079913, MI-710601)
Affinity DataIC50:  20.1nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119729(US8680132, C02701 | US9079913, C02701)
Affinity DataIC50:  27nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119742(US8680132, MI- 710801)
Affinity DataIC50:  32nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119730(US8680132, C02901 | US9079913, C02901)
Affinity DataIC50:  35nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119711(US8680132, MI- 519-64 | US9079913, MI-519-64)
Affinity DataIC50:  41.4nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119718(US8680132, C034 | US9079913, C034)
Affinity DataIC50:  48nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119733(US8680132, C03701 | US9079913, C03701)
Affinity DataIC50:  61nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119738(US8680132, MI- 710201 | US9079913, MI-710201)
Affinity DataIC50:  61.7nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119713(US8680132, MI- 773 | US9079913, MI-773)
Affinity DataIC50:  62.1nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119740(US8680132, MI- 710401 | US9079913, MI-710401)
Affinity DataIC50:  70.2nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119732(US8680132, C03401 | US9079913, C03401)
Affinity DataIC50:  85.6nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119731(US8680132, C03001 | US9079913, C03001)
Affinity DataIC50:  89.6nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119750(US8680132, C30201)
Affinity DataIC50: <100nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119731(US8680132, C03001 | US9079913, C03001)
Affinity DataIC50: <100nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119745(US8680132, CB061- Isomer B)
Affinity DataIC50: <100nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119749(US8680132, C29701)
Affinity DataIC50: <100nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119734(US8680132, C08301 | US9079913, C08301)
Affinity DataIC50: <100nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119710(US8680132, MI- 21901)
Affinity DataIC50:  104nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119732(US8680132, C03401 | US9079913, C03401)
Affinity DataIC50:  108nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119729(US8680132, C02701 | US9079913, C02701)
Affinity DataIC50:  112nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119731(US8680132, C03001 | US9079913, C03001)
Affinity DataIC50:  120nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119730(US8680132, C02901 | US9079913, C02901)
Affinity DataIC50:  122nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119740(US8680132, MI- 710401 | US9079913, MI-710401)
Affinity DataIC50:  138nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119729(US8680132, C02701 | US9079913, C02701)
Affinity DataIC50:  149nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119740(US8680132, MI- 710401 | US9079913, MI-710401)
Affinity DataIC50:  158nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119744(US8680132, C11701)
Affinity DataIC50:  159nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119730(US8680132, C02901 | US9079913, C02901)
Affinity DataIC50:  160nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119735(US8680132, C08601 | US9079913, C08601)
Affinity DataIC50:  162nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119715(US8680132, C027 | US9079913, C027)
Affinity DataIC50:  167nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119722(US8680132, MI- 7104)
Affinity DataIC50:  169nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119721(US8680132, MI- 7102 | US9079913, MI-7102)
Affinity DataIC50:  175nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119716(US8680132, C029 | US9079913, MI-7105)
Affinity DataIC50:  176nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM50300121((2'R,3S,4'R,5'R)-6-chloro-4'-(3-chlorophenyl)-N-((...)
Affinity DataIC50:  180nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119742(US8680132, MI- 710801)
Affinity DataIC50:  185nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119733(US8680132, C03701 | US9079913, C03701)
Affinity DataIC50:  220nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119742(US8680132, MI- 710801)
Affinity DataIC50:  225nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119741(US8680132, MI- 710601 | US9079913, MI-710601)
Affinity DataIC50:  256nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119739(US8680132, MI- 710301 | US9079913, MI-710301)
Affinity DataIC50:  260nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119733(US8680132, C03701 | US9079913, C03701)
Affinity DataIC50:  270nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119738(US8680132, MI- 710201 | US9079913, MI-710201)
Affinity DataIC50:  273nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119741(US8680132, MI- 710601 | US9079913, MI-710601)
Affinity DataIC50:  290nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119738(US8680132, MI- 710201 | US9079913, MI-710201)
Affinity DataIC50:  308nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM119739(US8680132, MI- 710301 | US9079913, MI-710301)
Affinity DataIC50:  309nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was optionally determined using a fluorescence polarization-based (FP-based) binding assay using a recomb...More data for this Ligand-Target Pair
In DepthDetails US Patent
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