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Compile Data Set for Download or QSAR
maximum 50k data
Found
57
of affinity data for UniProtKB/TrEMBL:
G7ZKZ7
Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM84994
(CAS_163091 | NSC_163091 | ORG-5222)
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Affinity Data
Ki: 0.170nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM30704
((phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a...)
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Affinity Data
Ki: 0.630nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50001786
(1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl...)
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Ki: 1.30nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50024204
(1H-imidazo[4,5-c]pyridine derivative | 2N-[4,7-dim...)
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Ki: 1.58nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50001775
((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
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Affinity Data
Ki: 2.10nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50031942
((6aR,9R)-4,6a,7-Trimethyl-4,6,6a,7,8,9-hexahydro-i...)
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Ki: 2.51nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50001775
((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
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Affinity Data
Ki: 2.51nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
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PDSP K
i
Database
Ligand
BDBM35255
(2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-t...)
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Ki: 2.90nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
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Affinity Data
Ki: 7.10nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM82088
(CAS_15574-96-6 | NSC_27400 | PIZOTIFEN)
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Affinity Data
Ki: 7.94nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
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i
Database
Ligand
BDBM84930
(CAS_60634-51-7 | LY 53857 | NSC_107989)
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Ki: 7.94nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Affinity Data
Ki: 9.5nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM35256
((S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+...)
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Affinity Data
Ki: 10nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Affinity Data
Ki: 11nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50048803
(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...)
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Affinity Data
Ki: 13nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Affinity Data
Ki: 13nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
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Affinity Data
Ki: 15.8nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM78940
(METHIOTHEPIN | MLS000859918 | Methiothepin mesylat...)
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Affinity Data
Ki: 25.1nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50252513
(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
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Affinity Data
Ki: 47nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
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Ki: 48nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
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Affinity Data
Ki: 63nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50252513
(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
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Affinity Data
Ki: 71nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50035057
((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...)
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Ki: 81nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM21395
(3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...)
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Ki: 100nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM82563
(CAS_182596 | NSC_182596 | S 15931)
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Ki: 115nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM81780
(CAS_6438382 | NSC_6438382 | SR 46349B)
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Ki: 120nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM81483
(CAS_1893-33-0 | NSC_4830 | PIPAMPERONE)
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Ki: 120nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM82505
(CAS_121881 | NSC_121881 | SB204070)
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Ki: 126nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM82562
(CAS_182595 | NSC_182595 | S 14489)
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Ki: 151nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50035057
((eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)...)
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Ki: 170nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM85672
(S33084)
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Ki: 200nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50026917
(8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...)
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Ki: 234nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
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i
Database
Ligand
BDBM50280934
(1-tert-Butylamino-3-(thiochroman-8-yloxy)-propan-2...)
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Ki: 363nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
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i
Database
Ligand
BDBM82518
(CAS_124756-23-6 | MDL 73005 EF)
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Ki: 427nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
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i
Database
Ligand
BDBM82564
(CAS_132787 | NSC_132787 | S 15535)
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Ki: 537nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
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i
Database
Ligand
BDBM79215
(CHEMBL15928 | GR 127935 | GR 127935 hydrochloride ...)
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Ki: 631nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
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i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Ki: 776nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
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Affinity Data
Ki: 977nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM84991
(CAS_3277600 | NSC_3277600 | SB204741)
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Ki: 1.00E+3nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM84991
(CAS_3277600 | NSC_3277600 | SB204741)
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Ki: 1.00E+3nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50240797
(6-((4-methoxyphenylsulfonyl)methyl)-N,N-dipropyl-1...)
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Affinity Data
Ki: 1.00E+3nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
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PDSP K
i
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Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
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Ki: 1.26E+3nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
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PDSP K
i
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Ligand
BDBM50013515
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
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Ki: 1.58E+3nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
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i
Database
Ligand
BDBM26948
(8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-tr...)
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Ki: 1.83E+3nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
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i
Database
Ligand
BDBM82369
(CAS_133025-23-7 | WAY 100,135 | WAY 100135)
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Ki: 3.47E+3nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
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i
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Ligand
BDBM50095890
(2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperaz...)
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Ki: 3.82E+3nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
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i
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Ligand
BDBM50056401
(2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]be...)
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Ki: 3.98E+3nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
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i
Database
Ligand
BDBM50050467
(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
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Ki: 3.98E+3nM
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5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
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i
Database
Ligand
BDBM25764
(ALPRENOLOL,(+) | ALPRENOLOL,(-) | Alfeprol | Alphe...)
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Ki: 4.47E+3nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Janssen Research Foundation
Curated by
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i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Ki: 5.00E+3nM
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