BDBM31774 CHEMBL104::Canesten::Clotrimazole::Lotrimin::Mycelex::US9138393, Clotrimazole::cid_2812

SMILES: c1ccc(cc1)C(c2ccccc2)(c3ccccc3Cl)n4ccnc4

InChI Key: InChIKey=VNFPBHJOKIVQEB-UHFFFAOYSA-N

Data: 7 KI  54 IC50  10 Kd  3 EC50

PDB links: 9 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 74 hits for monomerid = 31774   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lanosterol 14-alpha demethylase (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
C-C chemokine receptor type 4 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histidine-rich protein PFHRP-II (malaria parasite P. falciparum)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mouse)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 2 (Mouse)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aromatase (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Mouse)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Mouse)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Heme oxygenase 1 (Rat)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli (strain K12))	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mycocyclosin synthase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 3 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 3 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 3 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C8 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	803	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	883	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Guinea pig)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 130 (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium-transporting ATPase alpha chain 1/subunit beta (Pig)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transitional endoplasmic reticulum ATPase (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bovine)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 130 (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid C26-monooxygenase (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroid C26-monooxygenase (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 144 (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)	BDBM31774 (cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair