BDBM46667 2-phenyl-1,2-benzothiazol-3-one::2-phenyl-1,2-benzothiazol-3-one (1)::MLS-0107957.0001::acs.jmedchem.1c00409_ST.178::cid_164981

SMILES: O=c1n(sc2ccccc12)-c1ccccc1

InChI Key: InChIKey=KDMQSUUXKLZVNU-UHFFFAOYSA-N

Data: 1 KI  22 IC50  12 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 36 hits for monomerid = 46667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-lactamase (Pseudomonas aeruginosa)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glucose-6-phosphate 1-dehydrogenase (Leuconostoc mesenteroides)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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DNA dC->dU-editing enzyme APOBEC-3G (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	25
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DNA dC->dU-editing enzyme APOBEC-3A (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	25
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Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glucose-6-phosphate 1-dehydrogenase (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitochondrial peptide methionine sulfoxide reductase (Bovine)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.93E+4	n/a	n/a	n/a	n/a
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Regulator of G-protein signaling 19 (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
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Receptor-interacting serine/threonine-protein kinase 2 (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Genome polyprotein (Hepacivirus C)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	7.5	23
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Replicase polyprotein 1ab (2019-nCoV)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphoethanolamine/phosphocholine phosphatase (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphomannomutase 2 (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mannose-6-phosphate isomerase (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Eukaryotic translation initiation factor 4 gamma 1 (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mannose-6-phosphate isomerase (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphotransferase (Trypanosoma brucei brucei (strain 927/4 GUTat10.1))	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Phosphomannomutase 2 (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Phosphoethanolamine/phosphocholine phosphatase (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	941	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.11E+3	n/a	n/a	n/a	n/a
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Regulator of G-protein signaling 7 (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 19 (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 16 (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mannose-6-phosphate isomerase (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 4 (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
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Streptokinase A (Streptococcus pyogenes M1 GAS)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Phosphotransferase (Trypanosoma brucei brucei (strain 927/4 GUTat10.1))	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 4 (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	135	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 7 (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 16 (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 4 (Human)	BDBM46667 (2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...) Show SMILES Show InChI	GoogleScholar	UniChem		110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair