BDBM50207446 2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl)acetic acid::CHEMBL404108

SMILES: Cc1ccc(c(c1)CC(=O)O)Nc2c(cccc2Cl)F

InChI Key: InChIKey=KHPKQFYUPIUARC-UHFFFAOYSA-N

Data: 1 KI  13 IC50

PDB links: 6 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50207446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-binding cassette sub-family C member 4 (Human)	BDBM50207446 (2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50207446 (2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50207446 (2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50207446 (2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Mouse)	BDBM50207446 (2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM50207446 (2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM50207446 (2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50207446 (2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50207446 (2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50207446 (2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM50207446 (2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50207446 (2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50207446 (2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM50207446 (2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair