Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 131 hits in this display
BDBM50179097((3R,4S,5R,6R)-4-(decyloxy)-6-(hydroxymethyl)-tetra...)
BDBM50179112((3R,4S,5R,6R)-6-(hydroxymethyl)-4-(undecyloxy)-tet...)
BDBM50179111((3R,4S,5R,6R)-4-(dodecyloxy)-6-(hydroxymethyl)-tet...)
BDBM50179091((3R,4S,5R,6R)-6-(hydroxymethyl)-4-(octyloxy)-tetra...)
BDBM50179094((3R,4S,5R,6R)-6-(hydroxymethyl)-4-(nonyloxy)-tetra...)
BDBM34103(D-glucose | dextrose | glucose)
BDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
BDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
BDBM20876((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-methoxyoxane-...)Ki: 3.70E+5nMAssay Description:Inhibition of Escherichia coli Heptosyltransferase I assessed as reduction in ADP release using ODLA and ADP-heptose substrates in presence of phosph...More data for this Ligand-Target Pair
BDBM50179096((3R,4S,5R,6R)-6-(hydroxymethyl)-4-(octadecyloxy)-t...)
BDBM50179101((3R,4S,5R,6R)-6-(hydroxymethyl)-4-(tetradecyloxy)-...)
Ki: 5.00E+5nMAssay Description:Inhibition of Escherichia coli Heptosyltransferase I assessed as reduction in ADP release using ODLA and ADP-heptose substrates in presence of phosph...More data for this Ligand-Target Pair
BDBM50454778(CHEBI:320055 | CHEMBL132186)Ki: 6.80E+5nMAssay Description:Inhibition of Escherichia coli Heptosyltransferase I assessed as reduction in ADP release using ODLA and ADP-heptose substrates in presence of phosph...More data for this Ligand-Target Pair
BDBM50102882(6-Hydroxymethyl-tetrahydro-pyran-2,3,4,5-tetraol |...)
BDBM34103(D-glucose | dextrose | glucose)
BDBM50147883((S)-6-Hydroxymethyl-tetrahydro-pyran-2,3,4,5-tetra...)
BDBM34103(D-glucose | dextrose | glucose)
Ki: 4.91E+6nM ΔG°: -13.7kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ki: 5.61E+6nM ΔG°: -13.4kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
BDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Ki: 6.70E+6nMAssay Description:Displacement of [125I]-Man30-BSA from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by gamma-counting analysisMore data for this Ligand-Target Pair
BDBM34103(D-glucose | dextrose | glucose)
BDBM34103(D-glucose | dextrose | glucose)
BDBM50240803(CHEMBL1614854 | Glucoside | beta-D-glucopyranose |...)
BDBM34103(D-glucose | dextrose | glucose)
BDBM34103(D-glucose | dextrose | glucose)
BDBM20876((2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-methoxyoxane-...)
Ki: 1.31E+7nMAssay Description:Displacement of [125I]-Man30-BSA from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by gamma-counting analysisMore data for this Ligand-Target Pair
BDBM50147907((S)-2,6-Bis-hydroxymethyl-tetrahydro-pyran-2,3,4,5...)
BDBM50147927((R)-2-Hydroxymethyl-6-methoxy-tetrahydro-pyran-3,4...)
BDBM50454778(CHEBI:320055 | CHEMBL132186)
BDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
IC50: 910nMAssay Description:Competitive inhibition of N-(fluorescein-5-yl)-N'-(alpha-L-fucopyranosyl ethylen)-thiocarbamide binding to Pseudomonas aeruginosa PA14 LecB after 8 t...More data for this Ligand-Target Pair
BDBM50591453(CHEBI:42589 | CHEMBL1230861)
BDBM50166886(CHEMBL195368 | methyl alpha-D-mannoside)
BDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
BDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
BDBM50591453(CHEBI:42589 | CHEMBL1230861)
IC50: 2.74E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa LecB expressed in Escherichia coli BL21 (DE3) incubated for 6 hrs by Tecan-INFINITE F500 plate reader analysisMore data for this Ligand-Target Pair
BDBM50166886(CHEMBL195368 | methyl alpha-D-mannoside)
IC50: 3.70E+4nMAssay Description:Competitive inhibition of N-(fluorescein-5-yl)-N'-(alpha-L-fucopyranosyl ethylen)-thiocarbamide binding to Pseudomonas aeruginosa PA14 LecB after 8 t...More data for this Ligand-Target Pair
BDBM50166886(CHEMBL195368 | methyl alpha-D-mannoside)
IC50: 4.68E+4nMAssay Description:Competitive binding affinity to recombinant Pseudomonas aeruginosa PA14 LecB expressed in Escherichia coli BL21(DE3) incubated for 4 to 8 hrs by fluo...More data for this Ligand-Target Pair
BDBM50034081(CHEBI:55507 | CHEMBL467773)
IC50: 5.20E+4nMAssay Description:Competitive inhibition of N-(fluorescein-5-yl)-N'-(alpha-L-fucopyranosyl ethylen)-thiocarbamide binding to Pseudomonas aeruginosa PA14 LecB after 8 t...More data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
BDBM50166886(CHEMBL195368 | methyl alpha-D-mannoside)
IC50: 1.04E+5nMAssay Description:Competitive binding affinity to recombinant Pseudomonas aeruginosa PAO1 LecB expressed in Escherichia coli BL21(DE3) incubated for 4 to 8 hrs by fluo...More data for this Ligand-Target Pair
BDBM50034081(CHEBI:55507 | CHEMBL467773)
BDBM50166886(CHEMBL195368 | methyl alpha-D-mannoside)
BDBM50166886(CHEMBL195368 | methyl alpha-D-mannoside)
BDBM103981(LecB Inhibitor Compound 1)
BDBM50166886(CHEMBL195368 | methyl alpha-D-mannoside)
BDBM50077229(CHEMBL300520 | beta-D-galactopyranose | beta-D-gal...)
BDBM50166886(CHEMBL195368 | methyl alpha-D-mannoside)
BDBM50580865(CHEBI:42548 | CHEMBL1232862)IC50: 2.48E+6nMAssay Description:Inhibition of DC-SIGN extracellular domain (unknown origin) binding to HIV gp120 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
BDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
BDBM50467903(CHEBI:28729 | CHEMBL365590)IC50: 3.39E+6nMAssay Description:Inhibition of DC-SIGN extracellular domain (unknown origin) binding to HIV gp120 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
BDBM50467903(CHEBI:28729 | CHEMBL365590)
BDBM50240803(CHEMBL1614854 | Glucoside | beta-D-glucopyranose |...)
IC50: >3.00E+7nMAssay Description:Inhibition of D-GalNAc-PAA binding to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by competitive sol...More data for this Ligand-Target Pair
BDBM120768(US8703720, Reference Compound 1)
BDBM120768(US8703720, Reference Compound 1)
Kd: 4.40E+6nMAssay Description:Compounds 7, 15-19, and 22 were evaluated for their efficiency in inhibiting galectin-1 and galectin-3 in a known fluorescence polarization-based ass...More data for this Ligand-Target Pair
BDBM50034081(CHEBI:55507 | CHEMBL467773)
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
BDBM50034081(CHEBI:55507 | CHEMBL467773)
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
BDBM50034081(CHEBI:55507 | CHEMBL467773)
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
BDBM50034081(CHEBI:55507 | CHEMBL467773)
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
BDBM50034081(CHEBI:55507 | CHEMBL467773)
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
BDBM50034081(CHEBI:55507 | CHEMBL467773)
BDBM50244377(CHEMBL502337 | methyl beta-D-talopyranoside)
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
BDBM50244377(CHEMBL502337 | methyl beta-D-talopyranoside)
BDBM50244377(CHEMBL502337 | methyl beta-D-talopyranoside)
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
BDBM50077229(CHEMBL300520 | beta-D-galactopyranose | beta-D-gal...)
BDBM50240803(CHEMBL1614854 | Glucoside | beta-D-glucopyranose |...)
Kd: >1.00E+7nMAssay Description:Binding affinity to human recombinant ASGPR1 carbohydrate recognition domain expressed in Escherichia coli AD494 by surface plasmon resonance spectro...More data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
BDBM50249032(CHEBI:28645 | Dietade Dietary Foods | Fructose | L...)
Jacalin(Artocarpus heterophyllus)University Of Delaware
Curated by ChEMBL
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 1.00E+7nMAssay Description:Binding affinity at recombinant human C-terminal Galectin 4 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 4.10E+6nMAssay Description:Binding affinity at recombinant human Galectin 3 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: >1.00E+7nMAssay Description:Binding affinity at recombinant human Galectin 1 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 6.60E+6nMAssay Description:Binding affinity at recombinant human N-terminal Galectin 4 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Kd: 1.10E+7nMAssay Description:Binding affinity at recombinant human C-terminal Galectin 4 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 4.80E+6nMAssay Description:Binding affinity at recombinant human Galectin 7 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 6.30E+6nMAssay Description:Binding affinity at recombinant human N-terminal Galectin 8 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 3.30E+6nMAssay Description:Binding affinity at recombinant human N-terminal Galectin 9 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 8.60E+6nMAssay Description:Binding affinity at recombinant human C-terminal Galectin 9 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 1.30E+7nMAssay Description:Binding affinity at recombinant human Galectin 2 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Kd: 1.00E+7nMAssay Description:Binding affinity at recombinant human Galectin 1 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Kd: 1.00E+7nMAssay Description:Binding affinity at recombinant human Galectin 2 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: >3.00E+7nMAssay Description:Binding affinity at recombinant human C-terminal Galectin 8 expressed in Escherichia coli BL21 incubated for 5 mins by fluorescence anisotropy assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 1.00E+6nMAssay Description:Binding affinity to human galectin-4 C terminal domain assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 6.30E+6nMAssay Description:Binding affinity to human galectin-8 N terminal domain assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: >3.00E+7nMAssay Description:Binding affinity to human galectin-8 C terminal domain assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 3.30E+6nMAssay Description:Binding affinity to human galectin-9 N terminal domain assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 8.60E+6nMAssay Description:Binding affinity to human galectin-9 C terminal domain assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: >1.00E+7nMAssay Description:Binding affinity to human galectin-1 assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 1.30E+7nMAssay Description:Binding affinity to human galectin-2 assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 4.40E+6nMAssay Description:Binding affinity to human galectin-3 assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 6.60E+6nMAssay Description:Binding affinity to human galectin-4 N terminal domain assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 6.30E+6nMAssay Description:Binding affinity to human galactin-8 N terminal domain assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
BDBM50243888(CHEMBL442951 | methyl beta-D-galactopyranoside | m...)
Kd: 4.40E+6nMAssay Description:Binding affinity to human galactin-3 assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
BDBM50166886(CHEMBL195368 | methyl alpha-D-mannoside)
Kd: 430nMAssay Description:Binding affinity to recombinant Pseudomonas aeruginosa LecA expressed in Escherichia coli BL21 (DE3) expression system assessed as dissociation const...More data for this Ligand-Target Pair
BDBM50166886(CHEMBL195368 | methyl alpha-D-mannoside)
BDBM50467903(CHEBI:28729 | CHEMBL365590)
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