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Compounds Sorted by Binding Targets per Compound

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304   310   315   323   339   369   370   371   372   373   374   375   376   377   378   380   381   383   384   
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429   443   447   515   
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Binding Targets
Enz. Inhib. Data
ITC Data
Alternate Compound Names
  • β-Carbonic anhydrase 2 (CA 2)
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Carbonate dehydratase
  • Carbonic Anhydrase (hpCA)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase (mtCA 3)
  • Carbonic Anhydrase 2 (Can2)
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Carbonic anhydrase, alpha family
  • beta-Carbonic Anhydrase
46 Ki
  • 5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide
  • CHEMBL360356
  • Chlorzolamide, CHL
  • JMC522226 Compound 19
  • JMC523116 Compound 19
  • aromatic/heteroaromatic sulfonamide 20
  • ABL Mutant (T315I)
  • Angiopoietin-1 receptor
  • Cyclin-dependent kinase 2
  • Cyclin-dependent kinase 3 (CDK3)
  • Cyclin-dependent kinase 7
  • Cyclin-dependent-like kinase 5
  • Epithelial discoidin domain-containing receptor 1
  • Homeodomain-interacting protein kinase 1
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 12
  • PITSLRE serine/threonine-protein kinase CDC2L1
  • Platelet-derived growth factor receptor (PDGFr)
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Serine/threonine-protein kinase 10
  • Serine/threonine-protein kinase B-raf
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 3
21 Kd
  • US8765747, 2
  • 72 kDa type IV collagenase
  • Bile salt export pump
  • Butyrophilin subfamily 3 member A1
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
  • Farnesyl Diphosphate Synthase (FPPS)
  • Farnesyl diphosphate synthase
  • Farnesyl pyrophosphate synthase
  • Geranylgeranyl Diphosphate Synthase (GGPPS)
  • Geranylgeranyl diphosphate synthase (GGPPS)
  • Geranylgeranyl diphosphate synthase mutant (GGPPS Y107A/F108A)
  • Matrix metalloproteinase-14 (MMP14)
  • Multidrug resistance-associated protein 4
  • Octaprenyl diphosphate synthase (OPPS)
  • Putative farnesyl pyrophosphate synthase
  • Vacuolar-type proton translocating pyrophosphatase 1
6 Ki 64 IC50 4 EC50
2 ΔG°
  • 2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosphonic acid
  • Bisphosphonate 3
  • CGP-42446
  • CHEMBL924
  • JMC515594 Compound 55
  • Reclast
  • ZOL
  • Zoledronate
  • Zometa
  • [1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl]phosphonic acid
  • zoledronic acid
  • 3',5'-cyclic phosphodiesterase
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
  • Phosphodiesterase (TcrPDEC)
  • Phosphodiesterase 1
  • Phosphodiesterase 2A
  • Phosphodiesterase 3
  • Phosphodiesterase 3 (PDE3)
  • Phosphodiesterase 4
  • Phosphodiesterase 8
  • Phosphodiesterase Type 10 (PDE10A)
  • Phosphodiesterase Type 11 (PDE11A)
  • Phosphodiesterase Type 2 (PDE2A)
  • Phosphodiesterase Type 3 (PDE3B)
  • Phosphodiesterase Type 4 (PDE4B)
  • Phosphodiesterase Type 4 (PDE4D)
  • Phosphodiesterase Type 5 (PDE5A)
  • Phosphodiesterase Type 7 (PDE7B)
  • Phosphodiesterase Type 9 (PDE9A)
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • cGMP-specific 3',5'-cyclic phosphodiesterase
32 IC50
  • 6-(3,4-Dimethoxy-phenyl)-4,5-dimethyl-4,5-dihydro-2H-pyridazin-3-one
  • 6-(4-(difluoromethoxy)-3-methoxyphenyl)pyridazin-3(2H)-one
  • 6-(4-Difluoromethoxy-3-methoxy-phenyl)-2H-pyridazin-3-one
  • 6-[4-(difluoromethoxy)-3-methoxyphenyl]-2,3-dihydropyridazin-3-one
  • CHEMBL313842
  • Zaradaverine
  • Zardaverine
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
  • Hepatocyte nuclear factor 4-alpha
  • Homo sapiens phosphodiesterase 2A (PDE2A)
  • Phosphodiesterase 11A (PDE11A)
  • Phosphodiesterase 5
  • Phosphodiesterase 6
  • Phosphodiesterase 8
  • Phosphodiesterase 9A
  • Phosphodiesterase Type 10 (PDE10A)
  • Phosphodiesterase Type 11 (PDE11A)
  • Phosphodiesterase Type 2 (PDE2A)
  • Phosphodiesterase Type 3 (PDE3B)
  • Phosphodiesterase Type 4 (PDE4B)
  • Phosphodiesterase Type 4 (PDE4D)
  • Phosphodiesterase Type 5 (PDE5A)
  • Phosphodiesterase Type 7 (PDE7B)
  • Phosphodiesterase Type 9 (PDE9A)
  • cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
  • cGMP-specific 3',5'-cyclic phosphodiesterase
  • perilipin-1
  • perilipin-5
2 Ki 24 IC50
  • 2-{2-ethoxy-5-[(4-ethylpiperazine-1-)sulfonyl]phenyl}-5-methyl-7-propyl-3H,4H-imidazo[1,5-a][1,2,4]triazin-4-one
  • CHEMBL1520
  • VARDENAFIL
  • Vardenafil
  • citric acid;2-[2-ethoxy-5-(4-ethylpiperazino)sulfonyl-phenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one
  • vardenafil
  • Axin-1/Glycogen synthase kinase-3 beta
  • CAMK2B
  • CaM-kinase kinase beta
  • Casein kinase I isoform alpha
  • Casein kinase II alpha (prime)
  • Casein kinase II subunit alpha
  • Myosin light chain kinase
  • Myosin light chain kinase, smooth muscle
  • PKA
  • Protein kinase C alpha type
  • Protein kinase Pfmrk
  • RAC-alpha serine/threonine-protein kinase
  • Rho-associated protein kinase 2
  • Rho-associated protein kinase 2 (ROCK II)
  • Ribosomal protein S6 kinase (P70S6K)
  • Ribosomal protein S6 kinase alpha 5
  • Serine/threonine-protein kinase AKT
  • Serine/threonine-protein kinase AKT2
  • cAMP-Dependent Protein Kinase (PKA)
  • cAMP-dependent protein kinase (PKA)
  • cGMP-dependent protein kinase
15 Ki 23 IC50 4 Kd
  • CHEMBL104264
  • H-89
  • H89
  • HT-89 (H-89)
  • N-(2-{[(2E)-3-(4-bromophenyl)prop-2-en-1-yl]amino}ethyl)isoquinoline-5-sulfonamide
  • N-[2-[[(E)-3-(4-bromophenyl)prop-2-enyl]amino]ethyl]isoquinoline-5-sulfonamide
  • 17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3)
  • Acid-sensing ion channel 5
  • Aldo-keto reductase family 1 member C1
  • Aldo-keto reductase family 1 member C2
  • Aldo-keto reductase family 1 member C4 (AK1C4)
  • Aldo-keto reductase family member 1B10 (AKR1B10)
  • Aldo-keto-reductase family 1 member C3
  • Aldose reductase (AR)
  • Androgen Receptor
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • Cytochrome c oxidase subunit 2
  • Intestinal fatty acid-binding protein (hIFABP)
  • Myeloperoxidase (MPO)
  • Potassium channel subfamily K member 18
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Transcription factor SOX-18 (SOX-18)
  • Transcriptional enhancer factor TEF-3
  • Transient receptor potential cation channel subfamily A member 1
  • Transthyretin
  • Twik-RElated Potassium (K+) channel 1 (TREK1)
3 Ki 41 IC50 2 Kd 8 EC50
  • 2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid
  • Arlef
  • CHEMBL23588
  • Flufenamic acid
  • Nichisedan
  • US9271961, Flufenamic Acid
  • Adrenergic Alpha
  • Beta-N-acetyl-D-hexosaminidase-A/B
  • Beta-hexosaminidase subunit alpha (HexA)
  • Beta-hexosaminidase subunit beta (Hex B)
  • Bile salt export pump
  • Cytochrome P450 2C9
  • Dihydrofolate Reductase (DHFR)
  • Dihydrofolate Reductase-Thymidylate Synthase (DHFR-TS)
  • Dihydrofolate Reductase-Thymidylate Synthase (DHFR-TS) Mutant KICB1
  • Dihydrofolate Reductase-Thymidylate Synthase (DHFR-TS) Mutant SP21
  • Dihydrofolate Reductase-Thymidylate Synthase (DHFR-TS) Mutant V1/S
  • Dihydrofolate reductase
  • Dihydrofolate reductase (DHFR)
  • Dihydrofolate reductase; T. gondii vs rat
  • Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
  • Low molecular weight phosphotyrosine protein phosphatase
  • Multidrug and toxin extrusion protein 1
  • Pteridine reductase 1
  • Solute carrier family 22 member 1
  • Trace amine-associated receptor 5
  • streptokinase A precursor
42 Ki 71 IC50 4 Kd 2 EC50
  • 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
  • CHEMBL36
  • Pyrimethamine (Pyr)
  • cid_4993
  • Cereblon/Histone deacetylase 6
  • Coagulation factor VII/tissue factor
  • Histone Deacetylase (pfHDAC-1)
  • Histone Deacetylase 6 (HDAC6)
  • Histone Lysine Demethylase
  • Histone deacetylase 1
  • Histone deacetylase 1/3/5/8
  • Histone deacetylase 10
  • Histone deacetylase 11
  • Histone deacetylase 2
  • Histone deacetylase 3
  • Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
  • Histone deacetylase 4
  • Histone deacetylase 5
  • Histone deacetylase 6
  • Histone deacetylase 7
  • Histone deacetylase 8
  • Histone deacetylase 9
  • Histone deacetylase HD1B
  • Histone deacetylase HD2
  • Histone deacetylase-like amidohydrolase
9 Ki 174 IC50 2 Kd 4 EC50
1 ΔG°
  • (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide
  • CHEMBL99
  • TSA
  • Trichostatin A (TSA)
  • Histone Lysine Demethylase
  • Homo sapiens lysine demethylase 2A (KDM2A)
  • Lysine-specific demethylase 2B
  • Lysine-specific demethylase 3A
  • Lysine-specific demethylase 4A
  • Lysine-specific demethylase 4B
  • Lysine-specific demethylase 4C
  • Lysine-specific demethylase 4D
  • Lysine-specific demethylase 5A
  • Lysine-specific demethylase 5A (KDM5A(aa 1-1090)-Flag)
  • Lysine-specific demethylase 5A (KDM5A(aa 1-588)ΔAP)
  • Lysine-specific demethylase 5A (KDM5A(aa 1-739)ΔAP(2C-2S))
  • Lysine-specific demethylase 5A/5B
  • Lysine-specific demethylase 5B
  • Lysine-specific demethylase 5B (KDM5B(aa 1-604)ΔAP)
  • Lysine-specific demethylase 5B (KDM5B(aa 1-755)ΔAP)
  • Lysine-specific demethylase 5C
  • Lysine-specific demethylase 5C (KDM5C(aa 1-789)ΔAP)
  • Lysine-specific demethylase 5D (KDM5D(aa 1-760)ΔAP)
  • Lysine-specific demethylase 6B
  • Lysine-specific histone demethylase 1A
41 IC50 2 Kd 1 EC50
  • 2-(5-((4-chloro-2-methylbenzyl)oxy)-1Hpyrazol-1-yl)isonicotinic acid (N19)
  • US10173996, Example 89
  • US9604961, Example 89
  • US9714230, 89
  • US9908865, Example 89
  • Arachidonate 5-lipoxygenase
  • Bile salt export pump
  • COX-1
  • COX-2
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • Cyclooxygenase-2
  • Cyclooxygenase-2 (COX-2)
  • Cytochrome c oxidase subunit 1
  • Cytochrome c oxidase subunit 2
  • Dipeptidyl peptidase 3
  • EBifunctional epoxide hydrolase 2
  • Leukotriene 2
  • Multidrug resistance-associated protein 4
  • PTGER2
  • Prostaglandin E synthase/G/H synthase 2
  • Prostaglandin E2 receptor EP2 subtype
  • Prostaglandin G/H synthase (Cyclooxygenase-2)
  • Prostaglandin G/H synthase (cyclooxygenase)
26 Ki 162 IC50
  • 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one
  • CHEMBL122
  • MK 0966
  • Rofecoxib
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • ADRA1B
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Alpha-1D adrenergic receptor
  • Cerebral cortex alpha adrenergic receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Dopamine receptor
  • HTR6
  • HTR7
  • Histamine H1 receptor
  • Histamine H4 receptor
  • Potassium channel subfamily K member 9
  • Serotonin (5-HT) receptor
  • Serotonin 2 (5-HT2) receptor
  • TRAR1
  • ubiquitin-conjugating enzyme E2 N
27 Ki 8 IC50
  • 1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)-4-methyl-piperazine;maleate
  • 1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-4-methylpiperazine
  • 1-{6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-9-yl}-4-methylpiperazine
  • CHEMBL64249
  • CLOROTEPINE (+)
  • CLOROTEPINE(-)
  • Clothepin
  • OCTOCLOTHEPIN,(+)
  • OCTOCLOTHEPIN,(-)
  • Octoclothepin
  • Octoclothepine
  • Dual specificity protein phosphatase (VHR)
  • Dual specificity protein phosphatase VHX (VHX)
  • Fas-associated protein-tyrosine phosphatase 1 (FAP1)
  • Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • Laforin
  • Leukocyte common antigen
  • Megakaryocyte protein-tyrosine phosphatase (PTP-MEG2)
  • Protein-tyrosine phosphatase
  • Protein-tyrosine phosphatase 1B
  • Protein-tyrosine phosphatase 1C
  • Receptor-type tyrosine-protein phosphatase F (LAR)
  • Receptor-type tyrosine-protein phosphatase beta (PTPβ)
  • Receptor-type tyrosine-protein phosphatase epsilon (PTPε)
  • Receptor-type tyrosine-protein phosphatase gamma
  • Receptor-type tyrosine-protein phosphatase mu (PTPμ)
  • Tyrosine-protein phosphatase non-receptor type 11
  • Tyrosine-protein phosphatase non-receptor type 12 (PTP-PEST)
  • Tyrosine-protein phosphatase non-receptor type 2
  • Tyrosine-protein phosphatase non-receptor type 3 (PTPH1)
  • Tyrosine-protein phosphatase non-receptor type 9 (PTP-MEG2)
1 Ki 21 IC50
  • US9340574, 7
  • Cytochrome P450 1A
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Cytoplasmic tyrosine-protein kinase BMX
  • Epidermal growth factor receptor
  • Receptor protein-tyrosine kinase erbB-4
  • Receptor tyrosine-protein kinase erbB-2
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase TEC
  • Tyrosine-protein kinase TXK
56 IC50
  • US9447106, 27b (peak 2)
  • US9556188, Compound 27a
  • Alpha-ketoglutarate-dependent dioxygenase FTO
  • Beta-lactamase
  • Egl nine homolog 1
  • Egl nine homolog 2
  • Histone Lysine Demethylase
  • Homo sapiens lysine demethylase 2A (KDM2A)
  • Hypoxia-inducible factor 1 (FIH)
  • Lysine-specific demethylase 3A
  • Lysine-specific demethylase 4A (KDM4A)
  • Lysine-specific demethylase 4C
  • Lysine-specific demethylase 4D
  • Lysine-specific demethylase 5A
  • Lysine-specific demethylase 5A (KDM5A)
  • Lysine-specific demethylase 5B
  • Lysine-specific demethylase 5C
  • Lysine-specific demethylase 5C (KDM5C)
  • Lysine-specific demethylase 5D (KDM5D)
  • Lysine-specific demethylase 6A (KDM6A)
  • Lysine-specific demethylase 6B
  • Prolyl 4-hydroxylase
  • Trypanosoma brucei RNA editing ligase 1
9 Ki 46 IC50 1 Kd
  • 2,4 PDCA
  • cid_10365
  • pyridine carboxylate, 6a
  • pyridine-2,4-dicarboxylic acid
  • α-Carbonic anhydrase (αCA)
  • β-Carbonic anhydrase (βCA)
  • 5'-nucleotidase
  • Alpha carbonic anhydrase
  • Alpha-carbonic anhydrase
  • Beta-carbonic anhydrase
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Ecto-5'-nucleotidase (e5'NT)
  • Gamma-carbonic anhydrase
  • beta-Carbonic Anhydrase
82 Ki 6 IC50
  • CHEMBL68253
  • H2NSO3H
  • sulfamic acid
  • Beta-adrenergic receptor kinase 1
  • Beta-adrenergic receptor kinase 2
  • Cyclic AMP-dependent protein kinase (PKA)
  • G protein-coupled receptor kinase 4
  • G protein-coupled receptor kinase 5
  • G protein-coupled receptor kinase 6
  • G protein-coupled receptor kinase 7
  • PKC alpha and beta-2
  • Protein Kinase C
  • Protein kinase C (PKC)
  • Protein kinase C alpha type
  • Protein kinase C delta type
  • Protein kinase C iota type/zeta type
  • Protein kinase C, PKC; classical/novel
  • Protein kinase C, epsilon
  • Protein kinase C, eta
  • Protein kinase C, gamma
  • Rhodopsin kinase
  • cAMP-Dependent Protein Kinase (PKA)
  • cAMP-dependent protein kinase (PKA)
  • cGMP-dependent protein kinase 1 beta
2 Ki 106 IC50 4 Kd
  • 2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzene)amido]azepan-4-yl]oxy}carbonyl)phenyl]carbonyl}-3-hydroxybenzoic acid
  • Acyclic Balanol Analog (-)-1
  • Balanol analog 1
  • Balanol, 1
  • CHEMBL60254
  • Cellular retinoic acid-binding protein I
  • Cellular retinoic acid-binding protein II
  • NR2B Channel Blocker
  • Nuclear receptor ROR-gamma (RORC)
  • Oxysterols receptor LXR-alpha
  • Oxysterols receptor LXR-beta
  • Retinoic Acid Receptor, alpha
  • Retinoic Acid Receptor, beta
  • Retinoic Acid Receptor, gamma
  • Retinoic acid receptor RXR-alpha
  • Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta
  • Retinoic acid receptor RXR-alpha/gamma
  • Retinoic acid receptor alpha
  • Retinoic acid receptor alpha/Retinoid X receptor alpha
  • Retinoic acid receptor beta
  • Retinoic acid receptor gamma
  • Retinoid X receptor alpha
  • Retinoid X receptor beta
  • Retinoid X receptor gamma
  • Retinoid X receptor gamma/retinoic acid receptor alpha
  • Retinoid receptor
18 Ki 10 IC50 43 Kd 69 EC50
  • 9-cis retinoic acid
  • 9C-RA
  • CHEMBL705
  • Panretin
  • alitretinoin
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • Adrenaline alpha1
  • Adrenaline alpha2
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Chloroquine resistance transporter
  • HRH3
  • Histamine H1 receptor
  • Histamine H4 receptor
  • Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1)
  • Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)
  • Lethal(3)malignant brain tumor-like protein 4
  • MBT domain-containing protein 1 (MBTD1)
  • Multidrug resistance-associated protein 4
  • Muscarinic acetylcholine receptor M2
  • Platelet activating factor receptor
  • Potassium voltage-gated channel subfamily H member 2
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sodium channel protein type I I alpha subunit
25 Ki 23 IC50
  • 1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine
  • 1-(p-chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane
  • 3-(p-chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine
  • 5-HT,N-ACETYL
  • CHEMBL505
  • CHLORPHENIRAMINE
  • CHLORPHENIRAMINE MALEATE
  • Polaramin
  • Polaramine
  • Polaronil
  • [3H]Chlorphenamine
  • [3H]Chlorpheniramine
  • chlorophenylpyridamine
  • chlorphenamine
  • clorfeniramina
  • d-Chlorpheniramine
  • gamma-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine
  • gamma-(4-chlorophenyl)-gamma-(2-pyridyl)propyldimethylamine
  • Beta lactamase
  • DNA dC->dU-editing enzyme APOBEC-3G
  • G protein signalling regulator 19
  • Glucose 6-phosphate dehydrogenase (G6PD)
  • MPI protein
  • MSRA protein
  • Mannose-6-phosphate isomerase
  • NS3
  • RGS7
  • Regulator of G-protein signaling 8
  • Serine/threonine-protein kinase RIPK2
  • eukaryotic translation initiation factor 4 gamma, 1 isoform 4
  • glucose-6-phosphate dehydrogenase
  • glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase
  • hexokinase
  • phosphatase, orphan 1
  • phosphomannomutase 2
  • probable DNA dC->dU-editing enzyme APOBEC-3A
  • regulator of G-protein signaling 4
  • regulator of G-protein signalling 16
  • streptokinase A precursor
1 Ki 20 IC50 12 EC50
  • 2-phenyl-1,2-benzothiazol-3-one
  • 2-phenyl-1,2-benzothiazol-3-one (1)
  • MLS-0107957.0001
  • cid_164981
  • BRAF
  • Dual specificity mitogen-activated protein kinase kinase 1/Mitogen-activated protein kinase 1/RAF proto-oncogene serine/threonine-protein kinase
  • Dual specificity mitogen-activated protein kinase kinase 5
  • Dual specificity mitogen-activated protein kinase kinase 6
  • Dual specificity mitogen-activated protein kinase kinase 7 (MAP2K7)
  • FLT3-ITD
  • Mast/stem cell growth factor receptor Kit
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Receptor protein-tyrosine kinase erbB-4
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Fyn (Y531F)
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
  • flt3
17 IC50 5 Kd
  • (3S,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-1,2-dithiolan-4-ol
  • US10844038, Example 46 A.
  • 12-Lipoxygenase (12-LOX)
  • 5-lipoxygenase/FLAP
  • Arachidonate 15-lipoxygenase
  • Arachidonate 5-lipoxygenase
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • Cytochrome P450 1A
  • EBifunctional epoxide hydrolase 2
  • Leukotriene A4 hydrolase
  • Leukotriene B4 receptor
  • Leukotriene B4 receptor 2
  • Multidrug resistance-associated protein 4
  • Phospholipase A2, membrane associated
  • Prostaglandin E synthase/G/H synthase 2
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Thromboxane-A synthase
  • Tumor necrosis factor ligand superfamily member 11
1 Ki 130 IC50 1 EC50
  • (+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea
  • 1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea
  • CHEMBL93
  • Leutrol
  • N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea
  • N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea
  • ZILEUTON
  • Zyflo (TN)
  • Excitatory amino acid transporter 1
  • Excitatory amino acid transporter 2
  • Excitatory amino acid transporter 3
  • GRIA1
  • GRIA2
  • GRIA3
  • GRIK1
  • GRIK4
  • Glutamate receptor 1
  • Glutamate receptor ionotropic AMPA
  • Glutamate receptor ionotropic, AMPA
  • Glutamate receptor ionotropic, AMPA 2
  • Glutamate receptor ionotropic, AMPA 4
  • Glutamate receptor ionotropic, NMDA 1
  • Glutamate receptor ionotropic, kainate
  • Glutamate receptor ionotropic, kainate 1
  • Glutamate receptor ionotropic, kainate 2
  • Ionotropic glutamate receptor kainate 2/5
  • Metabotropic glutamate receptor 1
  • Metabotropic glutamate receptor 5
  • NMDA receptor subunit 2C (GluN2C)
33 Ki 6 IC50 8 EC50
  • (R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-propionic acid
  • (RS)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)-propionicacid
  • 2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid
  • 2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid(DL-AMPA)
  • 2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)-propionic acid
  • 2-amino-3-(5-methyl-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic acid
  • 2-ammonio-3-(3-hydroxy-5-methylisoxazol-4-yl)propanoate
  • AMPA
  • CHEMBL13378
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cytochrome P450 3A
  • Histone deacetylase 1
  • Histone deacetylase 2
  • Histone deacetylase 3
  • Multidrug resistance-associated protein 4
  • P-glycoprotein (P-gp)
  • P-glycoprotein 1
  • P-glycoprotein 1 and 3 (MDR1a/MDR1b)
  • Reverse transcriptase
  • Serine/threonine-protein kinase pim-1
  • Similar to alpha-tubulin isoform 1
  • Solute carrier family 22 member 3
  • Steroidogenic Factor 1
  • Tubulin
  • Tubulin alpha chain /beta chain
  • Tubulin beta chain
  • Tubulin polymerization-promoting protein
  • nuclear receptor subfamily 0 group B member 1
5 Ki 70 IC50 2 Kd 1 EC50
  • (S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide
  • (S)-colchicine
  • 7alphaH-colchicine
  • CHEMBL107
  • COLCHICINE
  • N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide
  • colchicina
  • colchicinum
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • Adrenergic alpha1B
  • Alpha-1A adrenergic receptor
  • Alpha-1D adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • HTR7
  • Histamine H1 receptor
26 Ki 3 IC50
  • 1,1-Diethyl-3-(7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-urea
  • CHEMBL73151
  • Terguride
  • 3C-like proteinase
  • 3C-like proteinase (3CL-PRO)
  • 5-hydroxytryptamine receptor 1A
  • Adrenergic Alpha
  • Alpha-1A adrenergic receptor
  • Bile salt export pump
  • Calmodulin
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Chloroquine resistance transporter
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • DRD1
  • Histamine H1 receptor
  • Histamine H4 receptor
  • Multidrug resistance-associated protein 4
  • Pleiotropic ABC efflux transporter of multiple drugs
  • Prion protein
  • Sodium channel protein type I I alpha subunit
  • Spike glycoprotein
  • Trypanothione reductase
14 Ki 15 IC50 1 Kd 3 EC50
  • (2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine
  • 10-(2-Dimethylaminopropyl)phenothiazine
  • 10-[2-(dimethylamino)propyl]phenothiazine
  • CHEMBL643
  • N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamine
  • N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine
  • PROMETHAZINE
  • med.21724, Compound 16
  • proazamine
  • 15-Lipoxygenase (LoxA)
  • Bile salt export pump
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 2J2
  • Cytochrome P450 3A
  • D(2) dopamine receptor
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Potassium channel subfamily K member 2
  • Sodium channel protein type I I alpha subunit
  • Sodium channel protein type II alpha subunit
  • Twik-RElated Potassium (K+) channel 1 (TREK1)
  • Voltage-dependent L-type calcium channel subunit beta-1/alpha-1B/alpha-2/delta-1
  • Voltage-dependent T-type calcium channel subunit alpha-1H
  • Voltage-gated T-type calcium channel
  • Voltage-gated calcium channel subunit alpha Cav2.2
  • streptokinase A precursor
2 Ki 22 IC50 5 Kd 3 EC50
  • 1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine
  • 1-[Bis-(4-fluoro-phenyl)-methyl]-4-((E)-3-phenyl-allyl)-piperazine
  • 1-[Bis-(4-fluoro-phenyl)-methyl]-4-(3-phenyl-allyl)-piperazine
  • 1-[Bis-(4-fluoro-phenyl)-methyl]-4-(3-phenyl-allyl)-piperazine(flunarizine)
  • CHEMBL30008
  • CHEMBL539027
  • Flunarizine
  • NCGC00018102
  • cid_6365505
  • ALK tyrosine kinase receptor
  • Fibroblast growth factor receptor 1
  • Fibroblast growth factor receptor 3
  • Focal adhesion kinase 1
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
  • PTK2B protein tyrosine kinase 2 beta (PTK2B)
  • Phosphorylase kinase
  • Platelet-derived growth factor receptor beta
  • Potassium voltage-gated channel subfamily H member 2
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Serine/threonine-protein kinase Chk1/2
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase ABL2
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor UFO
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 3
20 Ki 1 IC50
  • CHEMBL3288854
  • 5-HT2
  • 5-HT5B
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • 5-hydroxytryptamine receptor 7 (5HT7)
  • HTR2B
  • HTR2C
  • HTR5A
  • HTR6
  • HTR7
  • Serotonin (5-HT) receptor
  • Serotonin 1B/1D receptor
  • Serotonin 2 (5-HT2) receptor
  • Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
86 Ki 2 IC50
  • 1H-imidazo[4,5-c]pyridine derivative
  • 2N-[4,7-dimethyl-(6aR,9S,10aR)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]-2-dimethylaminosulfonamide
  • 4,7-dimethyl-(6aR,9S,10aR)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-amino-N,N-dimethyl sulfonamide
  • 4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-amine-sulfonamide
  • 9-N,N-dimethylsulfamide-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline
  • CHEMBL12314
  • ChEMBL_10959
  • MESULERGINE
  • N'-4,7-Dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-N'-,N'-dimethyl-sulphonediamine
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • D(2) dopamine receptor
  • HTR6
  • Histamine H1 receptor
  • Histamine H2 receptor
  • Histamine H4 receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Potassium voltage-gated channel subfamily H member 2
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
32 Ki 4 IC50
  • (3E)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine(3Z)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine
  • CHEMBL101740
  • DOXEPIN
  • cis-doxepin
  • 1,3-beta-glucan synthase component GLS2
  • Cacna1b/Cacnb3
  • Calcium channel (Type L)
  • Calcium release-activated calcium channel
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • P-glycoprotein (P-gp)
  • P-glycoprotein 1
  • P-glycoprotein 1 and 3 (MDR1a/MDR1b)
  • Potassium voltage-gated channel subfamily H member 2
  • Sodium channel protein type 5 subunit alpha
  • Sodium channel protein type 7 subunit alpha
  • Sodium channel protein type 9 subunit alpha
  • Twik-RElated Potassium (K+) channel 1 (TREK1)
  • Voltage-dependent T-type calcium channel subunit alpha-1H
  • Voltage-gated L-type calcium channel
  • Voltage-gated T-type calcium channel
  • Voltage-gated calcium channel
  • Voltage-gated calcium channel subunit alpha Cav2.2
  • Voltage-gated sodium channel
  • Voltage-gated sodium channel subunit alpha Nav1.4
4 Ki 74 IC50 1 EC50
  • (1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)(methyl)amino)ethyl)-6-fluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-yl 2-methoxyacetate
  • 2-{2-[3-(1H-benzoimidazol-2-yl)-propylamino]-ethyl}-6-fluoro-1-isopropyl-1,2,3,4-tetrahydro-naphthalen-2-yl ester(Mibefradil)Methoxy-acetic acid
  • CHEMBL45816
  • MIBEFRADIL
  • Methoxy-acetic acid (1S,2S)-2-(2-{[3-(1H-benzoimidazol-2-yl)-propyl]-methyl-amino}-ethyl)-6-fluoro-1-isopropyl-1,2,3,4-tetrahydro-naphthalen-2-yl ester
  • Methoxy-acetic acid 2-(2-{[3-(1H-benzoimidazol-2-yl)-propyl]-methyl-amino}-ethyl)-6-fluoro-1-isopropyl-1,2,3,4-tetrahydro-naphthalen-2-yl ester
  • Mibefradil dihydrochloride
  • 5-HT1
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • DRD1
  • Dopamine D1 receptor
  • HTR6
  • Histamine H1 receptor
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Serotonin (5-HT) receptor
57 Ki
  • 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one
  • 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)
  • CHEMBL460
  • MOLINDONE
  • Moban
  • 3-hydroxy-3-methylglutaryl-coenzyme A reductase
  • 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
  • Acetylcholinesterase
  • Bile Salt Export Pump, BSEP
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cholinesterase
  • Cystic fibrosis transmembrane conductance regulator
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • HMG-CoA reductase
  • Multidrug resistance-associated protein 2 (MRP2)
  • Multidrug resistance-associated protein 4
  • P-glycoprotein 1
  • Solute carrier organic anion transporter family member 1B1 (OATP1B1)
8 Ki 31 IC50 1 EC50
  • (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
  • 2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one
  • MK-733
  • SIMVASTATIN LACTONE
  • Simvastatin
  • Zocor
  • cid_54454
  • β-Carbonic anhydrase 2 (CA 2)
  • β-Carbonic anhydrase 3 (CA 3)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 13 (CA XIII)
  • Carbonic anhydrase 15
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Dihydroorotate dehydrogenase (fumarate)
  • Nuclear factor NF-kappa-B (NF-kB)
  • Protein tyrosine phosphatase 1B (PTP1B)
  • Tyrosinase
  • Xanthine dehydrogenase
23 Ki 6 IC50
  • (2E)-3-(2-hydroxyphenyl)-2-propenoic acid
  • (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid
  • (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid (7)
  • (E)-2-hydroxycinnamic acid
  • (E)-3-(2-hydroxyphenyl)-2-propenoic acid
  • (E)-o-hydroxycinnamic acid
  • CHEMBL52564
  • o-Hydroxycinnamic acid (o-HCA)
  • o-hydroxy-trans-cinnamic acid
  • trans-2-coumaric acid
  • trans-o-hydroxycinnamic acid
  • Bile acid receptor
  • Cytochrome P450 1A
  • Cytochrome P450 2A6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Glucocorticoid
  • Nuclear receptor ROR-alpha
  • Nuclear receptor ROR-beta
  • Nuclear receptor ROR-gamma
  • Nuclear receptor ROR-gamma (RORC)
  • Oxysterols receptor LXR-alpha
  • Peroxisome proliferator-activated receptor
  • Peroxisome proliferator-activated receptor alpha (PPAR alpha)
  • Peroxisome proliferator-activated receptor delta
  • Progesterone receptor
  • Retinoic acid receptor RXR-alpha
  • Retinoid receptor
  • Steroidogenic Factor 1
  • Vitamin D3 receptor
6 IC50 18 EC50
  • CHEMBL3774855
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
21 Ki
  • 4-(4-Fluoro-phenyl)-piperazine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
  • CHEMBL194206
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
21 Ki
  • 4-(4-Chloro-phenyl)-piperazine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
  • CHEMBL372453
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
21 Ki
  • 4-(2-Fluoro-phenyl)-piperazine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
  • CHEMBL196169
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
21 Ki
  • 4-(4-Methylsulfanyl-phenyl)-piperazine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
  • CHEMBL197796
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
21 Ki
  • 4-(2-Chloro-phenyl)-piperazine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
  • CHEMBL370128
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
21 Ki
  • 4-Biphenyl-4-yl-piperazine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
  • CHEMBL197408
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
21 Ki
  • 4-(4-Trifluoromethyl-phenyl)-piperazine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
  • CHEMBL196598
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
25 Ki
  • 4-(2-Methoxy-phenyl)-piperazine-1-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
  • CHEMBL196370
  • CHEMBL430500
  • Angiopoietin-1 receptor
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • RAF proto-oncogene serine/threonine-protein kinase
  • Ribosomal protein S6 kinase (P70S6K)
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase CSK
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
  • Vascular endothelial growth factor receptor 2
2 Ki 28 IC50
  • 7-(2,6-dimethylphenyl)-5-methyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)benzo[e][1,2,4]triazin-3-amine
  • 7-(2,6-dimethylphenyl)-5-methyl-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1,2,4-benzotriazin-3-amine
  • CHEMBL436137
  • US8481536, 322
  • 1,3-beta-glucan synthase component GLS2
  • BDNF/NT-3 growth factors receptor
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Cytochrome P450 1A
  • Cytochrome P450 2B6
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Cytoplasmic tyrosine-protein kinase BMX
  • High affinity nerve growth factor receptor
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Receptor protein-tyrosine kinase erbB-4
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase TEC
  • Tyrosine-protein kinase TXK
38 IC50
  • CHEMBL3918580
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • CDK2/CycE
  • CDK7/Cyclin H/MNAT1
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 9 (CDK9)
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Cyclin-dependent kinase 4
  • Ephrin type-B receptor 3 (EPHB3)
  • Glycogen synthase kinase-3
  • Mitogen-activated protein kinase 1
  • Protein kinase C alpha type
  • Protein kinase C delta type
  • RAC-alpha serine/threonine-protein kinase
  • Ribosomal protein S6 kinase alpha-3
  • Serine/threonine-protein kinase AKT
  • Tyrosine-protein kinase Fyn
17 Ki 17 IC50
  • (5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one
  • (Z)-5-(quinolin-6-ylmethylene)-2-(thiophen-2-ylmethylamino)thiazol-4(5H)-one
  • CHEMBL261644
  • CHEMBL393929
  • Alpha-1A adrenergic receptor
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Bile salt export pump
  • Cytochrome P450 2A13
  • Cytochrome P450 2A6
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • D(3) dopamine receptor
  • G-protein subunit alpha-16
  • Histone Lysine Demethylase
  • Homo sapiens lysine demethylase 2A (KDM2A)
  • LSD1/CoREST complex
  • Lysine-specific demethylase 3A
  • Lysine-specific demethylase 4C
  • Lysine-specific demethylase 5C
  • Lysine-specific demethylase 6B
  • Lysine-specific histone demethylase 1A
  • Lysine-specific histone demethylase 1A/REST corepressor
  • Lysine-specific histone demethylase 1B
  • trace amine-associated receptor 1
8 Ki 75 IC50 4 Kd 2 EC50
  • (1R,2S)-(-)-2-phenylcyclopropylamine
  • (1R,2S)-2-phenylcyclopropanamine
  • (tranylcypromine)2-Phenyl-cyclopropylamine
  • 2-Phenyl-cyclopropylamine
  • CHEMBL1179
  • Parnate
  • TRANYLCYPROMINE
  • TRANYLCYPROMINE HYDROCHLORIDE
  • US10836743, Compound TCP
  • US8993808, Tranylcypromine
  • US9180183, Tranylcypromine
  • cid_2723716
  • rel-Tranylcypromine
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • D(2) dopamine receptor
  • Histamine H1 receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Norepinephrine transporter
  • Potassium voltage-gated channel subfamily C member 1
  • Potassium voltage-gated channel subfamily H member 2
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • Twik-RElated Potassium (K+) channel 1 (TREK1)
37 Ki 5 IC50 1 EC50
  • (S)-Norfluoxetine
  • CHEMBL465123
  • NORFLUOXETINE
  • Aurora kinase A/Targeting protein for Xklp2
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Ephrin type-A receptor 2
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 2
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Leukocyte tyrosine kinase receptor
  • Macrophage-stimulating protein receptor
  • Mast/stem cell growth factor receptor Kit
  • Protein kinase C alpha type
  • RAC-alpha serine/threonine-protein kinase
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Yes
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor UFO
21 IC50
  • 2-(6-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)cyclopropanecarboxamide
  • CHEMBL602472
  • Aurora kinase B
  • Axin-1/Glycogen synthase kinase-3 beta
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Fibroblast growth factor receptor 1
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit alpha
  • MAP kinase-activated protein kinase 2
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase kinase kinase kinase 2
  • Platelet-derived growth factor receptor alpha
  • Protein kinase C alpha type
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 1
  • Ribosomal protein S6 kinase alpha 1
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lyn
  • Vascular endothelial growth factor receptor 2
21 IC50
  • 4-(3-((4-hydroxy-3-oxobenzofuran-2(3H)-ylidene)methyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-N-(2-hydroxyethyl)benzamide
  • CHEMBL1092754
  • 5'-AMP-activated protein kinase catalytic subunit alpha-1
  • Apoptosis Signal-regulating Kinase 1 (ASK1)
  • Axin-1/Glycogen synthase kinase-3 beta
  • Cyclin-dependent kinase 2
  • Ephrin type-A receptor 3 (EPHA3)
  • Epidermal growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • Macrophage-stimulating protein receptor
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase 3
  • Mitogen-activated protein kinase 8
  • Mitogen-activated protein kinase kinase kinase 1
  • Mitogen-activated protein kinase kinase kinase 6
  • Nuclear receptor subfamily 2 group C member 2
  • Protein kinase C theta type
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Receptor protein-tyrosine kinase erbB-4
  • Rho-associated protein kinase 1
  • Serine/threonine-protein kinase B-raf
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase Mer
23 IC50
  • CHEMBL1642655
  • CHEMBL2205637
  • N-(6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl)-4-tert-butylbenzamide
  • 8-Oxoguanine DNA glycosylase-1 (OGG1)
  • Beta-ketoacyl-ACP synthase III (FabH)
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cytochrome P450 1A
  • Cytochrome P450 2A6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 3A
  • DNA Gyrase
  • DNA gyrase subunit B
  • Dihydrofolate reductase
  • Enoyl-[acyl-carrier-protein] reductase [NADH]
  • Isocitrate lyase (ICL)
  • Multidrug resistance-associated protein 4
  • Myeloperoxidase (MPO)
  • MymA
  • Pantothenate synthetase
  • Tyrosinase
7 Ki 22 IC50
  • 4-pyridinecarbohydrazide(Isoniazid)
  • CHEMBL64
  • Dow-isoniazid
  • Hyzyd
  • INH
  • ISONICOTINIC ACID HYDRAZIDE(ISONIAZIDE)
  • Isoniazid (INH)
  • Isonicotinic acid hydrazide (Isoniazid)
  • Isonicotinic acid hydrazide(Isoniazid)
  • Isonicotinylhydrazine
  • Laniazid
  • Nydrazid
  • Rimifon
  • Stanozide
  • isoniazid
  • isonicotinamide
  • isonicotinhydrazide
  • isonicotinohydrazide
  • isonicotinyl hydrazide
  • pyridine-4-carbohydrazide
  • Aurora kinase A/Targeting protein for Xklp2
  • BDNF/NT-3 growth factors receptor
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Ferrochelatase R115L (FECH)
  • Fibroblast growth factor receptor 1
  • Fibroblast growth factor receptor 2
  • Fibroblast growth factor receptor 3
  • Hepatocyte growth factor receptor
  • High affinity nerve growth factor receptor
  • Macrophage-stimulating protein receptor
  • Potassium voltage-gated channel subfamily H member 2
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 3
32 IC50 3 Kd
  • CHEMBL1802916
  • MK-2461
  • Axin-1/Glycogen synthase kinase-3 beta
  • Casein kinase I isoform delta
  • Cyclin-dependent kinase 2
  • Cytochrome P450 2D6 (2D6)
  • Fibroblast growth factor receptor 1
  • Hepatocyte growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • Inhibitor of nuclear factor kappa-B kinase subunit epsilon
  • MAP kinase-activated protein kinase 2
  • Protein kinase C (PKC)
  • Proto-oncogene tyrosine-protein kinase Src
  • Serine/threonine-protein kinase CHK2
  • Serine/threonine-protein kinase Chk1/2
  • Serine/threonine-protein kinase PAK 4
  • Serine/threonine-protein kinase pim-2
  • Syk protein
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase receptor UFO
  • [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
21 IC50
  • CHEMBL1933550
  • Cyclin-dependent kinase 2
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Dual specificity mitogen-activated protein kinase kinase 2
  • Fibroblast growth factor receptor 1
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase 14
  • Protein kinase C alpha type
  • Protein kinase C delta type
  • Protein kinase C iota (PKCι)
  • Protein kinase C, eta
  • RAC-alpha serine/threonine-protein kinase
  • RAF proto-oncogene serine/threonine-protein kinase
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase SYK
  • Vascular endothelial growth factor receptor 2
2 Ki 20 IC50
  • CHEMBL259922
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • CaM kinase IV
  • Epidermal growth factor receptor
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • High affinity nerve growth factor receptor
  • Insulin-like growth factor I receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 8
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2
  • Serine/threonine-protein kinase Chk1/2
  • Serine/threonine-protein kinase PLK4
  • Serine/threonine-protein kinase receptor R3
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
22 IC50
  • CHEMBL1990583
  • 3-phosphoinositide dependent protein kinase-1
  • Aurora kinase B
  • Cell division cycle 7-related protein kinase
  • Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • RAC-alpha serine/threonine-protein kinase
  • RAF proto-oncogene serine/threonine-protein kinase
  • Serine/threonine-protein kinase Chk1/2
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
23 IC50
  • CHEMBL2152253
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 7
  • Adrenergic alpha1B
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2C adrenergic receptor
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Sigma non-opioid intracellular receptor 1
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
21 Ki
  • CHEMBL2205836
  • Coagulation Factor VIII
  • Coagulation factor IX
  • Coagulation factor X
  • Coagulation factor XI
  • Complement C1r subcomponent
  • Complement C1s
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Factor XIIa
  • Kallikrein-1 (KLK1)
  • Plasma kallikrein
  • Plasminogen
  • Prothrombin
  • Tissue-type plasminogen activator
  • Trypsin
  • Trypsin-1
  • Urokinase-type plasminogen activator
  • Vitamin K-dependent protein C
16 Ki 5 IC50
  • CHEMBL2315243
  • Coagulation Factor VIII
  • Coagulation factor IX
  • Coagulation factor X
  • Coagulation factor XI
  • Complement C1r subcomponent
  • Complement C1s
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Factor XIIa
  • Kallikrein-1 (KLK1)
  • Plasma kallikrein
  • Plasminogen
  • Prothrombin
  • Tissue-type plasminogen activator
  • Trypsin
  • Trypsin-1
  • Urokinase-type plasminogen activator
  • Vitamin K-dependent protein C
16 Ki 5 IC50
  • CHEMBL2315239
  • Angiopoietin-1 receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • CDK2/Cyclin A/Cyclin A1
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 3
21 IC50
  • CHEMBL2333163
  • Sesquibastadin 1
  • 1,3-beta-glucan synthase component GLS2
  • 3',5'-cyclic phosphodiesterase
  • 5-hydroxytryptamine receptor 1A
  • Acetylcholinesterase
  • Amine oxidase (flavin-containing) A
  • Angiotensin-converting enzyme
  • Arginase-1
  • Cannabinoid receptor 1
  • Carbonic anhydrase 2
  • Cyclooxygenase
  • D-3-phosphoglycerate dehydrogenase
  • D-alanine--D-alanine ligase
  • GABA-A receptor; alpha-1/beta-2/gamma-2
  • Indoleamine 2,3-dioxygenase
  • L-lactate dehydrogenase A chain
  • Monoglyceride lipase
  • Muscarinic acetylcholine receptor M1
  • Peroxisome proliferator-activated receptor
  • Prothrombin
  • Secretory phospholipase A2
  • Tyrosine-protein kinase Lck
21 IC50
  • CHEMBL4476621
  • CAAX prenyl protease 1 homolog
  • Cytochrome P450 3A
  • HIV-1 Protease
  • HIV-1 Protease AE
  • HIV-1 Protease AE Mutant (V82F)
  • HIV-1 Protease AE-P
  • HIV-1 Protease AE-P Mutant (F82V)
  • HIV-1 Protease B Subtype
  • HIV-1 Protease B Subtype Mutant (V82F)
  • HIV-1 Protease Mutant (L10I/L90M)
  • HIV-1 Protease Mutant (M46I/I54V)
  • HIV-1 Protease Mutant (V82A/I84V)
  • HIV-1 Protease Mutant M1 (L10I, G48V, I54V, L63P, V82A)
  • HIV-1 Protease Mutant M2 (D30N, L63P, N88D)
  • HIV-1 Protease Mutant M3 (L10I, L63P, A71V, G73S, I84V, L90M)
  • HIV-1 Protease Mutant, MDR-HM
  • HIV-1 Protease Mutant, MDR-QM
  • HIV-1 protease
  • Human immunodeficiency virus type 1 protease
  • P-glycoprotein 1
  • Potassium voltage-gated channel subfamily H member 2
17 Ki 5 IC50 1 Kd
6 ΔG°
  • (2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
  • ABT-378
  • Aluviran
  • CHEMBL729
  • LPV
  • Lopinavir
  • Axin-1/Glycogen synthase kinase-3 beta
  • CDK2/CycE
  • CDK7/Cyclin H/MNAT1
  • CaM Kinase II
  • Casein kinase I delta
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 9 (CDK9)
  • Dual specificity protein kinase CLK3
  • Dual specificty protein kinase CLK1
  • ERK-2
  • Epidermal growth factor receptor
  • Glycogen Synthase Kinase-3, beta
  • Insulin receptor
  • Interferon-induced, double-stranded RNA-activated protein kinase
  • Platelet-derived growth factor receptor beta
  • VEGFR-2 (KDR)
  • Vascular endothelial growth factor receptor 2
  • cAMP-Dependent Protein Kinase (PKA)
24 IC50
  • 1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3n
  • 5-amino-N-(2,6-difluorophenyl)-3-[(4-sulfamoylphenyl)amino]-1H-1,2,4-triazole-1-carbothioamide
  • 10 kDa chaperonin
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 3A
  • 5-hydroxytryptamine receptor 4 (5-HT4)
  • 60 kDa chaperonin
  • Adenosine receptor A1
  • Adrenaline alpha1
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • HSP60/HSP10
  • HTR2C
  • HTR4
  • Serotonin (5-HT) receptor
  • Serotonin 1d (5-HT1d) receptor
  • Serotonin 4 (5-HT4) receptor
  • Thiosulfate sulfurtransferase
  • adrenergic Alpha2
28 Ki 8 IC50 1 Kd
  • CAS_121881
  • NSC_121881
  • SB204070
  • 5-hydroxytryptamine receptor 1A (5HT1B)
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 7
  • ADRA1B
  • Cytochrome P450 19A1
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • D(2) dopamine receptor
  • DRD3
  • HTR1D
  • HTR1E
  • HTR1F
  • HTR4
  • Serotonin (5-HT) receptor
  • Sodium-dependent serotonin transporter
  • Tyrosine-protein kinase Fyn
30 Ki 11 IC50
  • CAS_181632-25-7
  • CHEMBL14563
  • SB 242084
  • 5-HT3A Serotonin Receptor
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 3A
  • 5-hydroxytryptamine receptor 7
  • Alpha-1A adrenergic receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • Gamma-aminobutyric acid type B receptor subunit 1
  • HRH3
  • Histamine H1 receptor
  • Histamine H2 receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • adrenergic Alpha2
21 Ki
  • CAS_62865
  • Cyamemazine
  • NSC_62865
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Mammalian target of Rapamycin (mTORC1)
  • Multidrug resistance-associated protein 4
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Phosphatidylinositol 3-kinase catalytic subunit type 3
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
  • Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
  • Phosphoinositide 3-Kinase (PI3K), delta
  • Phosphoinositide 3-Kinase (PI3K), gamma
  • Serine-protein kinase ATM
  • Tyrosine-protein kinase JAK3
  • mTOR/FKBP12A/FKBP12B
  • mTORC2
  • p110α/p85α
  • p110β/p85α
2 Ki 100 IC50 8 EC50
  • US9284315, BEZ-235
  • mTOR Inhibitor, BEZ235
  • Cytoplasmic tyrosine-protein kinase BMX
  • Epidermal growth factor receptor
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor protein-tyrosine kinase erbB-4
  • Receptor tyrosine-protein kinase erbB-2
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase CSK
  • Tyrosine-protein kinase FER
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase TEC
  • Tyrosine-protein kinase Yes
54 IC50
  • US8476284, 40
  • US9133201, 10
  • US9181263, 9
  • US9278100, 9