BDBM244612 US10226449, cpd 221::US9428502, 221
SMILES Cc1ccc(cc1-c1[nH]c(CO)nc1C#N)C(=O)N1CC(C1)c1ccc(cc1)C#N
InChI Key InChIKey=PDYGVRQAMDQWBJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 244612
Affinity DataIC50: 43nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:The antiviral activities of the compounds were assessed using the HCV1b replicon system. The replicon was constructed using the ET (luc-ubi-neo/ET) c...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair