BDBM50009860 2-(6-Methoxy-naphthalen-2-yl)-propionic acid::2-(6-Methoxy-naphthalen-2-yl)-propionic acid(naproxen)::2-(6-methoxy-2-naphthyl)propanoic acid::2-(6-methoxynaphthalen-2-yl)propanoic acid::CHEMBL154::Naproxen::Naproxen2-(6-Methoxy-naphthalen-2-yl)-propionic acid

SMILES COc1ccc2cc(ccc2c1)C(C)C(O)=O

InChI Key InChIKey=CMWTZPSULFXXJA-UHFFFAOYSA-N

Data  5 KI  10 IC50

PDB links: 10 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50009860   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50009860(2-(6-Methoxy-naphthalen-2-yl)-propionic acid | 2-(...)Copy SMILESCopy InChI

Affinity DataIC50:  2.43E+4nMAssay Description:Compound was tested in vitro for inhibition of human umbilical cord endothelial cells(ECV-304 cell line) Prostaglandin G/H synthase 2 at 10 microMMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLKEGGMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticleMMDB
PDB3D Structure (crystal)
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TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50009860(2-(6-Methoxy-naphthalen-2-yl)-propionic acid | 2-(...)Copy SMILESCopy InChI

Affinity DataIC50:  350nMAssay Description:Compound was tested in vitro for inhibition of human platelet Prostaglandin G/H synthase 1 at 10 microMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLKEGGMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails Article
Copy BDB DOI