BDBM50024824 1,2,3,4-Tetrahydro-isoquinolin-5-ol::CHEMBL308021

SMILES Oc1cccc2CNCCc12

InChI Key InChIKey=OMZHCCXUVSEGAD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50024824   

LigandPNGBDBM50024824(1,2,3,4-Tetrahydro-isoquinolin-5-ol | CHEMBL308021)
Affinity DataKi:  2.22E+3nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50024824(1,2,3,4-Tetrahydro-isoquinolin-5-ol | CHEMBL308021)
Affinity DataKi:  1.76E+4nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylethanolamine N-methyltransferase(Bos taurus (bovine))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50024824(1,2,3,4-Tetrahydro-isoquinolin-5-ol | CHEMBL308021)
Affinity DataKi:  9.00E+4nMAssay Description:In vitro inhibition of bovine phenylethylamine N-methyl-transferase (PNMT) using radiochemical assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed