BDBM50100414 1-(4-Hydroxy-5-hydroxymethyl-3-octyloxy-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione::BDBM50206490::CHEMBL400411

SMILES CCCCCCCCO[C@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cc(C)c(=O)[nH]c1=O

InChI Key InChIKey=KSJKYOFITYMQNA-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50100414   

TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Universit£

Curated by ChEMBL
LigandPNGBDBM50100414(1-(4-Hydroxy-5-hydroxymethyl-3-octyloxy-tetrahydro...)
Affinity DataIC50: >1.00E+6nMAssay Description:Compound was evaluated for inhibitory activity towards nicotinic acetylcholine receptor in rat P2 brain membranes using [3H]-nicotine as a radioligan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
Universit£

Curated by ChEMBL
LigandPNGBDBM50100414(1-(4-Hydroxy-5-hydroxymethyl-3-octyloxy-tetrahydro...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration against Drosophila melanogaster deoxyribonucleoside kinase (Dm-dNK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50100414(1-(4-Hydroxy-5-hydroxymethyl-3-octyloxy-tetrahydro...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration against cytosolic thymidine kinase (TK-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
Universit£

Curated by ChEMBL
LigandPNGBDBM50100414(1-(4-Hydroxy-5-hydroxymethyl-3-octyloxy-tetrahydro...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory concentration against Varicella- zoster virus thymidine kinase(VZV TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
Universit£

Curated by ChEMBL
LigandPNGBDBM50100414(1-(4-Hydroxy-5-hydroxymethyl-3-octyloxy-tetrahydro...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of VZV TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100414(1-(4-Hydroxy-5-hydroxymethyl-3-octyloxy-tetrahydro...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxynucleoside kinase(Drosophila melanogaster)
Universit£

Curated by ChEMBL
LigandPNGBDBM50100414(1-(4-Hydroxy-5-hydroxymethyl-3-octyloxy-tetrahydro...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Drosophila melanogaster dNK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100414(1-(4-Hydroxy-5-hydroxymethyl-3-octyloxy-tetrahydro...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of HSV1 TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase, cytosolic(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50100414(1-(4-Hydroxy-5-hydroxymethyl-3-octyloxy-tetrahydro...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human TK1 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase 2, mitochondrial(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50100414(1-(4-Hydroxy-5-hydroxymethyl-3-octyloxy-tetrahydro...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibitory concentration against mitochondrial thymidine kinase (TK-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed