BDBM50135800 (-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandelate::17-cyclopropylmethyl-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol::3-Hydroxy-N-cyclopropylmethylmorphinan::CHEMBL49269::CYCLORPHAN::US10231963, Table B.6::US10736890, Compound TABLE B.6::US11534436, Compound Table B.6::US9656961, Example 00123
SMILES Oc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CC3)c2c1
InChI Key InChIKey=NLBUEDSBXVNAPB-DFQSSKMNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50135800
Affinity DataIC50: 0.710nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as DAMGO-stimulated [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.710nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
Affinity DataIC50: 0.710nMAssay Description:The Ki (binding affinity) for opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Journal of ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.710nMAssay Description:The Ki (binding affinity) for μ opioid receptors was determined using a competitive displacement assay as previously described in Neumeyer (Jour...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity was determined in stimulating [35S]-GTP-gamma S binding mediated by the Opioid receptor mu 1 in chinese Hamster Ovary (CHO)membra...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding by scintillatio...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [33S]GTPgammaS binding after 60 mins b...More data for this Ligand-Target Pair