BDBM50135800 (-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandelate::17-cyclopropylmethyl-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol::3-Hydroxy-N-cyclopropylmethylmorphinan::CHEMBL49269::CYCLORPHAN::US10231963, Table B.6::US10736890, Compound TABLE B.6::US11534436, Compound Table B.6::US9656961, Example 00123

SMILES Oc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CC3)c2c1

InChI Key InChIKey=NLBUEDSBXVNAPB-DFQSSKMNSA-N

Data  31 KI  9 IC50  12 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135800   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)
Affinity DataKi:  0.0340nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity against opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50135800((-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandel...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity against opioid receptor delta 1 using [3H]-naltrindole as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed