BDBM50420299 CHEMBL2089034

SMILES CC(C)n1cnc2c(NCc3ccc(cc3)-c3ccccn3)nc(nc12)N1C[C@H](O)C[C@H]1CO

InChI Key InChIKey=OQUWTJLQOZIRFA-VQTJNVASSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50420299   

TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420299(CHEMBL2089034)
Affinity DataIC50:  610nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50420299(CHEMBL2089034)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420299(CHEMBL2089034)
Affinity DataIC50:  390nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420299(CHEMBL2089034)
Affinity DataIC50:  450nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed