BDBM629718 US20230340011, Example 10.::US20230340011, Example 12.

SMILES [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(=O)N(C)OCC

InChI Key InChIKey=MTPMZVFOMVXGMD-ZHHJOTBYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 629718   

TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Asteroid Therapeutics

US Patent
LigandPNGBDBM629718(US20230340011, Example 10. | US20230340011, Exampl...)
Affinity DataIC50:  125nMAssay Description:10,000 cells/well of the PathHunter U2OS SREBP-2 Nuclear Translocation Cell Line are plated in quadruplicate on 384 well plates in 20 μL of Assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Asteroid Therapeutics

US Patent
LigandPNGBDBM629718(US20230340011, Example 10. | US20230340011, Exampl...)
Affinity DataIC50:  625nMAssay Description:PathHunter NHR CHO cells stably transfected with tagged full-length human LXRβ and a nuclear fusion protein containing Steroid Receptor Co-activ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Asteroid Therapeutics

US Patent
LigandPNGBDBM629718(US20230340011, Example 10. | US20230340011, Exampl...)
Affinity DataIC50:  125nMAssay Description:PathHunter NHR CHO cells stably transfected with tagged full-length human LXRβ and a nuclear fusion protein containing Steroid Receptor Co-activ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent