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Found 746 with Last Name = 'milne' and Initial = 'gw'
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50041389(Butyric acid (1aR,4aR,7aS,7bS,8R,9R,9aS)-9-butyryl...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity (Ki) towards Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049135((E)-3-{(S)-2-Hydroxymethyl-4-[(Z)-nonadec-10-en-(Z...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H-20]-PDBU from recombinant Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049142(Acetic acid (R)-2-hydroxymethyl-4-[(Z)-nonadec-10-...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H-20]-PDBU from recombinant Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049051(Acetic acid (R)-2-hydroxymethyl-4-[(Z)-octadec-9-e...)
Affinity DataKi:  12nMAssay Description:Displacement of phorbol 12,13-dibutyrate (PDBU) from Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049052(Acetic acid (R)-2-hydroxymethyl-4-[(Z)-octadec-9-e...)
Affinity DataKi:  13nMAssay Description:Displacement of phorbol 12,13-dibutyrate (PDBU) from Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049141(Acetic acid (R)-2-hydroxymethyl-4-[(Z)-nonadec-10-...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H-20]-PDBU from recombinant Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049143((S)-5-Hydroxymethyl-3-[(Z)-octadec-9-en-(Z)-yliden...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H-20]-PDBU from recombinant Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50041401((1S,3R,4S,9R,13S,14R)-13-Hydroxy-9-((R)-1-hydroxy-...)
Affinity DataKi:  20nMAssay Description:Binding affinity (Ki) towards Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049138((E)-3-{(S)-2-Hydroxymethyl-4-[(Z)-nonadec-10-en-(E...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H-20]-PDBU from recombinant Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50048885(Acetic acid 2-hydroxymethyl-4-[(Z)-octadec-9-en-(E...)
Affinity DataKi:  24nMAssay Description:Displacement of [H-20]phorbol12,13-dibutyrate (PDBU) from Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049050(Acetic acid 2-hydroxymethyl-4-[(Z)-octadec-9-en-(Z...)
Affinity DataKi:  24nMAssay Description:Displacement of phorbol 12,13-dibutyrate (PDBU) from Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049134((S)-5-Hydroxymethyl-3-[(Z)-octadec-9-en-(E)-yliden...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H-20]-PDBU from recombinant Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50048885(Acetic acid 2-hydroxymethyl-4-[(Z)-octadec-9-en-(E...)
Affinity DataKi:  28nMAssay Description:Displacement of phorbol 12,13-dibutyrate (PDBU) from Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50048882(Acetic acid 2-hydroxymethyl-5-oxo-4-[(Z)-tetradec-...)
Affinity DataKi:  28nMAssay Description:Displacement of [H-20]phorbol12,13-dibutyrate (PDBU) from Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50048888(Acetic acid 2-hydroxymethyl-5-oxo-4-tetradec-(Z)-y...)
Affinity DataKi:  35nMAssay Description:Displacement of [H-20]phorbol12,13-dibutyrate (PDBU) from Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50048890(Acetic acid 2-hydroxymethyl-5-oxo-4-tetradec-(E)-y...)
Affinity DataKi:  78nMAssay Description:Displacement of [H-20]phorbol12,13-dibutyrate (PDBU) from Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50048886((Z)-Octadec-9-enoic acid 2-hydroxymethyl-5-oxo-tet...)
Affinity DataKi:  96nMAssay Description:Displacement of [H-20]phorbol12,13-dibutyrate (PDBU) from Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049049(CHEMBL119907 | Tetradecanoic acid (R)-2-hydroxymet...)
Affinity DataKi:  96nMAssay Description:Displacement of phorbol 12,13-dibutyrate (PDBU) from Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049140((E)-3-((S)-2-Hydroxymethyl-5-oxo-tetrahydro-furan-...)
Affinity DataKi:  109nMAssay Description:Displacement of [3H-20]-PDBU from recombinant Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50048889(CHEMBL299225 | Tetradecanoic acid 2-hydroxymethyl-...)
Affinity DataKi:  138nMAssay Description:Displacement of phorbol 12,13-dibutyrate (PDBU) from Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50048889(CHEMBL299225 | Tetradecanoic acid 2-hydroxymethyl-...)
Affinity DataKi:  138nMAssay Description:Displacement of [H-20]phorbol12,13-dibutyrate (PDBU) from Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049133(3-((S)-2-Hydroxymethyl-5-oxo-tetrahydro-furan-2-yl...)
Affinity DataKi:  260nMAssay Description:Displacement of [3H-20]-PDBU from recombinant Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049145(3-(2-Hydroxymethyl-5-oxo-tetrahydro-furan-2-yl)-pr...)
Affinity DataKi:  489nMAssay Description:Displacement of [3H-20]-PDBU from recombinant Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50041403((2R,3R,4R)-2-Hydroxymethyl-5-oxo-4-tetradecyl-tetr...)
Affinity DataKi:  500nMAssay Description:Binding affinity (Ki) towards Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049137((S)-5-Hydroxymethyl-3-[(Z)-octadec-9-en-(Z)-yliden...)
Affinity DataKi:  746nMAssay Description:Displacement of [3H-20]-PDBU from recombinant Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50280897(CHEMBL281660 | Tetradecanoic acid (2S,3R)-2-(2-hyd...)
Affinity DataKi:  880nMAssay Description:Inhibition of [20-3H]phorbol-12,13-dibutyrate(PDBU) binding to purified PK-C alphaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50041391(CHEMBL13259 | Tetradecanoic acid (S)-2-acetoxy-3-h...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity (Ki) towards Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50280896(CHEMBL276429 | Tetradecanoic acid (2S,3R)-2-hydrox...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of [20-3H]phorbol-12,13-dibutyrate(PDBU) binding to purified PK-C alphaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049139((S)-5-Hydroxymethyl-3-[(Z)-octadec-9-en-(E)-yliden...)
Affinity DataKi:  2.02E+3nMAssay Description:Displacement of [3H-20]-PDBU from recombinant Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50041390((R)-5-Hydroxymethyl-4-tetradecanoyl-dihydro-furan-...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity (Ki) towards Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50280896(CHEMBL276429 | Tetradecanoic acid (2S,3R)-2-hydrox...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of [3H]phorbol-12,13-dibutyrate binding to PK-CMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50041399(CHEMBL26734 | Undecanoic acid (2S,3R)-2-hydroxymet...)
Affinity DataKi:  4.10E+3nMAssay Description:Binding affinity (Ki) towards Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50041397(CHEMBL13044 | Tetradecanoic acid (2R,3S)-2-hydroxy...)
Affinity DataKi:  5.30E+3nMAssay Description:Binding affinity (Ki) towards Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50048883(Acetic acid 3-hydroxy-5-oxo-4-tetradec-(E)-ylidene...)
Affinity DataKi:  6.50E+3nMAssay Description:Displacement of [H-20]phorbol12,13-dibutyrate (PDBU) from Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50048884(Acetic acid 3-hydroxymethyl-5-oxo-4-tetradec-(Z)-y...)
Affinity DataKi:  6.51E+3nMAssay Description:Displacement of [H-20]phorbol12,13-dibutyrate (PDBU) from Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50041402((3S,3aR,6aS)-3-Dodecyl-6a-hydroxymethyl-tetrahydro...)
Affinity DataKi:  7.60E+3nMAssay Description:Binding affinity (Ki) towards Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50041404((3S,3aR,6aR)-6a-Hydroxymethyl-3-undecyl-tetrahydro...)
Affinity DataKi:  7.70E+3nMAssay Description:Binding affinity (Ki) towards Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50035468(4-(4-Hydroxy-9,10-dioxo-9,10-dihydro-anthracen-1-y...)
Affinity DataKi:  7.80E+3nMAssay Description:Binding affinity of the compound with protein kinase C (PK-C) alpha bound to labeled [20-3H]-PDBU at a conc of 30 ug/mLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50041398(CHEMBL282101 | Nonadecanoic acid (2S,3R)-2-hydroxy...)
Affinity DataKi:  8.70E+3nMAssay Description:Binding affinity (Ki) towards Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50048887(CHEMBL96773 | Tetradecanoic acid 3-hydroxymethyl-5...)
Affinity DataKi:  9.81E+3nMAssay Description:Displacement of [H-20]phorbol12,13-dibutyrate (PDBU) from Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50035469(2-hydroxy-1-(2-hydroxy-1-phenylcarbonyloxyethyl)-3...)
Affinity DataKi:  1.29E+4nMAssay Description:Binding affinity of the compound with protein kinase C (PK-C) alpha bound to labeled [20-3H]-PDBU at a conc of 30 ug/mLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50041395((5R,6S)-9-Dodec-(E)-ylidene-6-hydroxymethyl-1,7-di...)
Affinity DataKi:  1.36E+4nMAssay Description:Binding affinity (Ki) towards Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50035466(2-[1-[Bis-(2-hydroxy-ethyl)-amino]-meth-(Z)-yliden...)
Affinity DataKi:  1.61E+4nMAssay Description:Binding affinity of the compound with protein kinase C (PK-C) alpha bound to labeled [20-3H]-PDBU at a conc of 30 ug/mLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50041393((3R,3aS,6aS)-6a-Hydroxymethyl-3-undecyl-tetrahydro...)
Affinity DataKi:  2.20E+4nMAssay Description:Binding affinity (Ki) towards Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50035467(3-(4-Hydroxy-9,10-dioxo-9,10-dihydro-anthracen-1-y...)
Affinity DataKi:  2.66E+4nMAssay Description:Binding affinity of the compound with protein kinase C (PK-C) alpha bound to labeled [20-3H]-PDBU at a conc of 30 ug/mLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049136((E)-3-((R)-2-Hydroxymethyl-5-oxo-tetrahydro-furan-...)
Affinity DataKi:  2.72E+4nMAssay Description:Displacement of [3H-20]-PDBU from recombinant Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50049144(3-((R)-2-Hydroxymethyl-5-oxo-tetrahydro-furan-2-yl...)
Affinity DataKi:  2.73E+4nMAssay Description:Displacement of [3H-20]-PDBU from recombinant Protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50041400((3S,3aR,6R,6aS)-6-Hydroxymethyl-3-undecyl-tetrahyd...)
Affinity DataKi:  2.78E+4nMAssay Description:Binding affinity (Ki) towards Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50041394(CHEMBL26372 | Tetradecanoic acid (2S,3S)-2-hydroxy...)
Affinity DataKi:  3.10E+4nMAssay Description:Binding affinity (Ki) towards Protein kinase CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50035470(Acetic acid 2-((1S,2R,4aR,5S,8aR)-6-acetoxy-5-acet...)
Affinity DataKi:  3.77E+4nMAssay Description:Binding affinity of the compound with protein kinase C (PK-C) alpha bound to labeled [20-3H]-PDBU at a conc of 30 ug/mLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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