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Found 42 with Last Name = 'donovan' and Initial = 'p'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50101075((2S,3S)-3-(3,4-Dichloro-phenyl)-2-methoxycarbonyl-...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in transfected cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50197471((2R,3S)-methyl 3-(3,4-dichlorophenyl)-8-thia-bicyc...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in transfected cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50101075((2S,3S)-3-(3,4-Dichloro-phenyl)-2-methoxycarbonyl-...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50197471((2R,3S)-methyl 3-(3,4-dichlorophenyl)-8-thia-bicyc...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50197486((2S,3S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)
Affinity DataIC50:  3.30nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in transfected cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50197486((2S,3S)-methyl 3-(3,4-dichlorophenyl)-8-oxa-bicycl...)
Affinity DataIC50:  4.70nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374510(CHEMBL255140)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in transfected cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374515(CHEMBL399740)
Affinity DataIC50:  11nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in transfected cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374519(CHEMBL256046)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in transfected cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374518(CHEMBL271707)
Affinity DataIC50:  17nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374516(CHEMBL257482)
Affinity DataIC50:  28nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in transfected cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374518(CHEMBL271707)
Affinity DataIC50:  31nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in transfected cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374515(CHEMBL399740)
Affinity DataIC50:  31nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374510(CHEMBL255140)
Affinity DataIC50:  53nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374512(CHEMBL270659)
Affinity DataIC50:  55nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in transfected cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374516(CHEMBL257482)
Affinity DataIC50:  56nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374513(CHEMBL401554)
Affinity DataIC50:  67nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in transfected cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374519(CHEMBL256046)
Affinity DataIC50:  106nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374514(CHEMBL403660)
Affinity DataIC50:  115nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in transfected cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374514(CHEMBL403660)
Affinity DataIC50:  140nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374513(CHEMBL401554)
Affinity DataIC50:  405nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374512(CHEMBL270659)
Affinity DataIC50:  593nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374517(CHEMBL407902)
Affinity DataIC50:  992nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374511(CHEMBL279331)
Affinity DataIC50:  1.54E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in transfected cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374511(CHEMBL279331)
Affinity DataIC50:  2.20E+3nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50374517(CHEMBL407902)
Affinity DataIC50:  2.96E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in transfected cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319090((E)-3-(4-Acetyl-phenyl)-N-[4-(1-hydroxy-6-nitro-1H...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa 388 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319080((E)-N-(4-(6-cyano-1-hydroxy-1H-benzo[d]imidazol-2-...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319088((E)-2-(2-(4-(3-(4-acetylphenyl)acrylamido)phenyl)-...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319089((E)-2-(2-(4-(3-(6-acetylpyridin-3-yl)acrylamido)ph...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319081((E)-N-(4-(1-hydroxy-6-nitro-1H-benzo[d]imidazol-2-...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319079((E)-N-(4-(1-hydroxy-6-nitro-1H-benzo[d]imidazol-2-...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319078((E)-N-(4-(6-cyano-1-hydroxy-1H-benzo[d]imidazol-2-...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319092((E)-3-(6-acetylpyridin-3-yl)-N-(4-(1-hydroxy-6-nit...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa 388 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319093((E)-N-(4-(1-hydroxy-6-nitro-1H-benzo[d]imidazol-2-...)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319091((E)-3-(4-acetylphenyl)-N-(4-(6-cyano-1-hydroxy-1H-...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa 388 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319082((E)-3-(6-(1H-imidazol-1-yl)pyridin-3-yl)-N-(4-(1-h...)
Affinity DataIC50:  3.12E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319085((E)-3-(4-acetylphenyl)-N-(2-amino-2-oxoethyl)-N-(4...)
Affinity DataIC50: >4.75E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319086((E)-3-(4-acetylphenyl)-N-(2-amino-2-oxoethyl)-N-(4...)
Affinity DataIC50: >4.90E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319087((E)-2-(3-(4-acetylphenyl)-N-(4-(6-cyano-1-hydroxy-...)
Affinity DataIC50: >5.10E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319083((E)-3-(6-(dimethylamino)pyridin-3-yl)-N-(4-(1-hydr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHTH-type transcriptional regulator ExsA(Pseudomonas aeruginosa)
Paratek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319084((E)-N-(4-(1-hydroxy-6-nitro-1H-benzo[d]imidazol-2-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 ExsA DNA binding activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed