Compile Data Set for Download or QSAR
maximum 50k data
Found 279 with Last Name = 'etienne' and Initial = 'jb'
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50122928(5-{6-[5-Chloro-2-(3-methyl-isoxazol-5-ylmethoxy)-b...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182312((2S,3S,4R,5R)-5-(6-(3,5-dichlorobenzylamino)-9H-pu...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182322((2S,3S,4R,5R)-5-(6-(2,5-dimethoxybenzylamino)-9H-p...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50118812((2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylami...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50118812((2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylami...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50122927((2S,3S,4R,5R)-3,4-dihydroxy-N-methyl-5-(6-(methyla...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50122927((2S,3S,4R,5R)-3,4-dihydroxy-N-methyl-5-(6-(methyla...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50122926(3-Amino-5-{6-[5-chloro-2-(3-methyl-isoxazol-5-ylme...)
Affinity DataKi:  5.80nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182326((2S,3S,4R,5R)-5-(6-(2-(2-amino-2-oxoethoxy)-5-chlo...)
Affinity DataKi:  6.80nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182313((2S,3S,4R,5R)-5-(6-(5-chloro-2-(2-(4-(dimethylamin...)
Affinity DataKi:  9.10nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182324((2S,3S,4R,5R)-5-(6-(5-chloro-2-(2-oxo-2-(piperazin...)
Affinity DataKi:  9.40nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)
Affinity DataKi:  14nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182323((2S,3S,4R,5R)-5-(6-(5-chloro-2-methoxybenzylamino)...)
Affinity DataKi:  15nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182321((2S,3S,4R,5R)-5-(6-(2-(benzyloxy)-5-chlorobenzylam...)
Affinity DataKi:  16nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182311((2S,3S,4R,5R)-5-(6-(5-chloro-2-(2-oxo-2-(piperidin...)
Affinity DataKi:  18nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50118812((2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylami...)
Affinity DataKi:  20nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182318((2S,3S,4R,5R)-5-(6-(5-chloro-2-(2-morpholino-2-oxo...)
Affinity DataKi:  20nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182325((2S,3S,4R,5R)-5-(6-(3,5-dichlorobenzylamino)-9H-pu...)
Affinity DataKi:  25nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182320((2S,4R,5R)-4-hydroxy-N-methyl-5-(6-(methylamino)-9...)
Affinity DataKi:  59nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50122927((2S,3S,4R,5R)-3,4-dihydroxy-N-methyl-5-(6-(methyla...)
Affinity DataKi:  65nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50122928(5-{6-[5-Chloro-2-(3-methyl-isoxazol-5-ylmethoxy)-b...)
Affinity DataKi:  68nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50122929(3-Amino-4-hydroxy-5-[6-(3-iodo-benzylamino)-purin-...)
Affinity DataKi:  72nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182317((2S,3S,5R)-3-hydroxy-N-methyl-5-(6-(methylamino)-9...)
Affinity DataKi:  87nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM21221((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...)
Affinity DataKi:  99nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50122930((2S,3S,4R,5R)-3-amino-4-hydroxy-N-methyl-5-(6-(met...)
Affinity DataKi:  120nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50122930((2S,3S,4R,5R)-3-amino-4-hydroxy-N-methyl-5-(6-(met...)
Affinity DataKi:  120nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182319(2-(2-((9-((2R,3R,4S,5S)-4-amino-3-hydroxy-5-(methy...)
Affinity DataKi:  130nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182327((2S,3S,4R,5R)-5-(6-(2,5-dimethoxybenzylamino)-9H-p...)
Affinity DataKi:  160nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182316(1-ethyl-3-((2S,3S,4R,5R)-4-hydroxy-5-(6-(methylami...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182315((2S,3S,4R,5R)-4-hydroxy-N-methyl-5-(6-(methylamino...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50182314((2S,3S,4R,5R)-3-acetamido-4-hydroxy-N-methyl-5-(6-...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50122929(3-Amino-4-hydroxy-5-[6-(3-iodo-benzylamino)-purin-...)
Affinity DataKi:  4.60E+3nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50122926(3-Amino-5-{6-[5-chloro-2-(3-methyl-isoxazol-5-ylme...)
Affinity DataKi:  7.30E+3nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50122930((2S,3S,4R,5R)-3-amino-4-hydroxy-N-methyl-5-(6-(met...)
Affinity DataKi:  2.30E+4nMAssay Description:Binding affinity using [125I]-ABA against human Adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344013(CHEMBL1780094 | trans-(3R,5S)-N-((6-aminopyridin-2...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344014(CHEMBL1779987 | trans-(3R,5S)-1-((5-methyl-2-pheny...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50390333(CHEMBL2070733)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344015(CHEMBL1780096 | trans-(3S,5S)-5-ethyl-1-((5-methyl...)
Affinity DataIC50:  0.955nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50390334(CHEMBL2070735)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50390332(CHEMBL2070732)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344018(CHEMBL1779984 | trans-(3R,5R)-5-ethyl-1-((5-methyl...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344017(1-((5-methyl-2-phenyloxazol-4-yl)methyl)-N-((6-met...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344016(2-((5-methyl-2-phenyloxazol-4-yl)methyl)-N-((6-met...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50390334(CHEMBL2070735)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344019(CHEMBL1780085 | trans-(3R,5R)-5-(methoxymethyl)-1-...)
Affinity DataIC50:  1.96nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344020(CHEMBL1780116 | trans-(3R,5R)-5-ethyl-1-((5-methyl...)
Affinity DataIC50:  2.91nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344021(CHEMBL1779988 | trans-(3R,5R)-5-(methoxymethyl)-1-...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50390373(CHEMBL2070914)
Affinity DataIC50:  3.63nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344022(CHEMBL1780100 | trans-(3S,5S)-5-(3-methyl-1,2,4-ox...)
Affinity DataIC50:  3.86nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50344023(CHEMBL1780089 | trans-(3R,5R)-5-(3-methyl-1,2,4-ox...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 279 total ) | Next | Last >>
Jump to: