TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Flt4 (unknown origin) after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at VDR expressed in COS7 cells assessed as inhibition of 1,25-Dihydroxyvitamin D3-induced response by transient transcription ass...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of KDR (unknown origin) after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of GST-Flt1 kinase domain (unknown origin) expressed in baculovirus infected Sf9 cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Antagonist activity at VDR expressed in COS7 cells assessed as inhibition of 1,25-Dihydroxyvitamin D3-induced response by transient transcription ass...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PDGFR-alpha (unknown origin) after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of PDGFR-beta (unknown origin) after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of PDGFR-beta (unknown origin) after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of Flt4 (unknown origin) after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KDR (unknown origin) after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of EGFR (unknown origin) after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of GST-Flt1 kinase domain (unknown origin) expressed in baculovirus infected Sf9 cells after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of PDGFR-alpha (unknown origin) after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory activity against Syk C-terminal SH2 domain in in-silico screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibitory activity against Syk C-terminal SH2.More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory activity against Syk C-terminal SH2.More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibitory activity against Syk C-terminal SH2.More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibitory activity against Syk C-terminal SH2.More data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibitory activity against Syk C-terminal SH2.More data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibitory activity against Syk C-terminal SH2.More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Institute Of Microbial Chemistry (Bikaken)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFR (unknown origin) after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibitory activity against Syk C-terminal SH2.More data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+6nMAssay Description:Inhibitory activity against Syk C-terminal SH2.More data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+6nMAssay Description:Inhibitory activity against Syk C-terminal SH2.More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+6nMAssay Description:Inhibitory activity against Syk C-terminal SH2 (at 10 mM)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+7nMAssay Description:Inhibitory activity against Syk C-terminal SH2.More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at VDR assessed as receptor transactivation by transient transcription assayMore data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Agonist activity at VDR assessed as receptor transactivation by transient transcription assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0200nMAssay Description:Agonist activity at VDR assessed as receptor transactivation by transient transcription assayMore data for this Ligand-Target Pair