Affinity DataKi: 8nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical
Curated by ChEMBL
Takeda Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 430nMAssay Description:ATP competitive inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 expressed in Escherichia coli BL21(DE3) ...More data for this Ligand-Target Pair
Affinity DataKi: 960nMAssay Description:Inhibition of human thrombin after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 6.20E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 7.50E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of human plasmin after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of tPA (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of human tPA after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 6.70E+4nMAssay Description:Inhibition of human tPAMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of recombinant human preprorenin expressed in human 293F cells using angiotensinogen as substrate preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of recombinant human preprorenin expressed in human 293F cells using angiotensinogen as substrate preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Inhibition of recombinant human preprorenin expressed in human 293F cells using angiotensinogen as substrate preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:Inhibition of recombinant human renin expressed in FreeStyle 293 expression system using recombinant human angiotensinogen as substrate preincubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.630nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.640nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.660nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.660nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.720nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.840nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.840nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of C-terminal biotin-labelled BCoR (Arg498 to 514Pro residues) binding to recombinant FLAG-tagged BCL6 BTB (5 to 129 residues) (unknown or...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of renin in monkey plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human renin using angiotensinogen as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair