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Found 85 with Last Name = 'misko' and Initial = 'tp'
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064015(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)
Affinity DataKi:  90nMAssay Description:Inhibitory activity against L-arginine binding to Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064015(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)
Affinity DataIC50:  160nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064018(7-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064015(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)
Affinity DataIC50:  460nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50225106((2S)-2-amino-5-{[(E)-amino(nitroimino)methyl]amino...)
Affinity DataIC50:  500nMAssay Description:Tested for inhibition of mouse inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049252(2-Amino-5-(N-nitro-guanidino)-pentanoic acid | CHE...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064011(7-Butyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049252(2-Amino-5-(N-nitro-guanidino)-pentanoic acid | CHE...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50064018(7-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50:  600nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50064015(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)
Affinity DataIC50:  600nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064011(7-Butyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50:  850nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human nNeuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatogra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064018(7-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50:  870nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049255(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049255(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064010(3-Ethyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50064011(7-Butyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50:  1.60E+3nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049258(CHEMBL161118 | [1,3]Oxazinan-(2E)-ylideneamine)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory activity against human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064013(7-(2-Ethyl-butyl)-azepan-(2Z)-ylideneamine; hydroc...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Rattus norvegicus)
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50072297((S)-5-Acetimidoylamino-2-amino-pent | (S)-5-Acetim...)
Affinity DataIC50:  2.20E+3nMAssay Description:Tested for inhibition of rat brain inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064010(3-Ethyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatographyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049250(CHEMBL306541 | [1,3]Thiazinan-(2E)-ylideneamine | ...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibitory activity against human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049250(CHEMBL306541 | [1,3]Thiazinan-(2E)-ylideneamine | ...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50064013(7-(2-Ethyl-butyl)-azepan-(2Z)-ylideneamine; hydroc...)
Affinity DataIC50:  3.30E+3nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)
Affinity DataIC50:  3.30E+3nMAssay Description:Tested for inhibition of mouse inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049257(Azepan-(2Z)-ylideneamine | CHEMBL315857 | CHEMBL54...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50064010(3-Ethyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50:  3.50E+3nMAssay Description:The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049258(CHEMBL161118 | [1,3]Oxazinan-(2E)-ylideneamine)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064014((R)-6-Methyl-azepan-(2Z)-ylideneamine; hydrochlori...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human nNeuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatogra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50072297((S)-5-Acetimidoylamino-2-amino-pent | (S)-5-Acetim...)
Affinity DataIC50:  3.90E+3nMAssay Description:Tested for inhibition of mouse inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibitory activity against human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049255(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064013(7-(2-Ethyl-butyl)-azepan-(2Z)-ylideneamine; hydroc...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064019(5-Methyl-azepan-(2Z)-ylideneamine; hydrochloride |...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064012(3-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049254((2S)-2-amino-5-(N-methylcarbamimidamido)pentanoic ...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064017(7-Phenyl-azepan-(2Z)-ylideneamine; hydrochloride |...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049256(Azonan-(2Z)-ylideneamine | CHEMBL158641)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049250(CHEMBL306541 | [1,3]Thiazinan-(2E)-ylideneamine | ...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049252(2-Amino-5-(N-nitro-guanidino)-pentanoic acid | CHE...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibitory activity against human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50064014((R)-6-Methyl-azepan-(2Z)-ylideneamine; hydrochlori...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049258(CHEMBL161118 | [1,3]Oxazinan-(2E)-ylideneamine)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50030279(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Affinity DataIC50:  8.30E+3nMAssay Description:Tested for inhibition of mouse inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
G. D. Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50064015(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibitory activity evaluated from soluble cell extract of human endothelia constitutive enzyme (Endothelial nitric oxide synthase) and partially pur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049256(Azonan-(2Z)-ylideneamine | CHEMBL158641)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibitory activity against human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049249(Azocan-(2Z)-ylideneamine | CHEMBL329431)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049254((2S)-2-amino-5-(N-methylcarbamimidamido)pentanoic ...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049249(Azocan-(2Z)-ylideneamine | CHEMBL329431)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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