Compile Data Set for Download or QSAR
maximum 50k data
Found 433 with Last Name = 'muto' and Initial = 't'
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50173539(1-(4-Hydroxy-5-trityloxymethyl-tetrahydro-furan-2-...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50094223(CHEMBL3586033)
Affinity DataIC50:  0.230nMAssay Description:Inverse agonist activity at rat ghrelin receptor expressed in HEK293 cells by NFAT-RE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096215(CHEMBL3593815)
Affinity DataIC50:  0.280nMAssay Description:Displacement of [125I]human ghrelin from rat ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096216(CHEMBL3593636)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [125I]human ghrelin from human ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096217(CHEMBL3593632)
Affinity DataIC50:  0.390nMAssay Description:Displacement of [125I]human ghrelin from human ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096220(CHEMBL3593635)
Affinity DataIC50:  0.420nMAssay Description:Displacement of [125I]human ghrelin from human ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096215(CHEMBL3593815)
Affinity DataIC50:  0.440nMAssay Description:Displacement of [125I]human ghrelin from human ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096217(CHEMBL3593632)
Affinity DataIC50:  0.960nMAssay Description:Displacement of [125I]human ghrelin from rat ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50094224(CHEMBL3586032)
Affinity DataIC50:  0.960nMAssay Description:Inverse agonist activity at rat ghrelin receptor expressed in HEK293 cells by NFAT-RE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096218(CHEMBL3593633)
Affinity DataIC50:  2.10nMAssay Description:Displacement of [125I]human ghrelin from rat ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096214(CHEMBL3593814)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]human ghrelin from human ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM134267(US8846660, 41)
Affinity DataIC50:  3nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the compounds of the present invention for recombinant human chymase was measured by the method of Pasztor et al. (Pasztor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM134262(US8846660, 30)
Affinity DataIC50:  4nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the compounds of the present invention for recombinant human chymase was measured by the method of Pasztor et al. (Pasztor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50094223(CHEMBL3586033)
Affinity DataIC50:  4.10nMAssay Description:Inverse agonist activity at rat ghrelin receptor expressed in HEK293 cells by NFAT-RE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50097492(CHEMBL3586019)
Affinity DataIC50:  5.20nMAssay Description:Inverse agonist activity at rat ghrelin receptor by inositol phosphate turnover assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096215(CHEMBL3593815)
Affinity DataIC50:  5.40nMAssay Description:Inverse agonist activity rat ghrelin receptor expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50094226(CHEMBL3586030)
Affinity DataIC50:  5.40nMAssay Description:Inverse agonist activity at rat ghrelin receptor expressed in HEK293 cells by NFAT-RE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096216(CHEMBL3593636)
Affinity DataIC50:  5.60nMAssay Description:Displacement of [125I]human ghrelin from rat ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096220(CHEMBL3593635)
Affinity DataIC50:  5.90nMAssay Description:Displacement of [125I]human ghrelin from rat ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096214(CHEMBL3593814)
Affinity DataIC50:  6.60nMAssay Description:Displacement of [125I]human ghrelin from rat ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50094229(CHEMBL3586027)
Affinity DataIC50:  6.90nMAssay Description:Inverse agonist activity at rat ghrelin receptor expressed in HEK293 cells by NFAT-RE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM134278(US8846660, 96)
Affinity DataIC50:  7nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the compounds of the present invention for recombinant human chymase was measured by the method of Pasztor et al. (Pasztor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50094227(CHEMBL3586029)
Affinity DataIC50:  7.20nMAssay Description:Inverse agonist activity at rat ghrelin receptor expressed in HEK293 cells by NFAT-RE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM50452609(CHEMBL4206099)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of recombinant human chymase pre-incubated for 10 mins before Suc-Ala-Ala-Pro-Phe-MCA substrate addition and measured after 10 mins by flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM134276(US8846660, 76)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the compounds of the present invention for recombinant human chymase was measured by the method of Pasztor et al. (Pasztor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096219(CHEMBL3593634)
Affinity DataIC50:  9.10nMAssay Description:Displacement of [125I]human ghrelin from rat ghrelin receptor expressed in CHO cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096220(CHEMBL3593635)
Affinity DataIC50:  9.40nMAssay Description:Inverse agonist activity rat ghrelin receptor expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096216(CHEMBL3593636)
Affinity DataIC50:  9.80nMAssay Description:Inverse agonist activity rat ghrelin receptor expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM134263(US8846660, 31)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the compounds of the present invention for recombinant human chymase was measured by the method of Pasztor et al. (Pasztor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM134266(US8846660, 40)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the compounds of the present invention for recombinant human chymase was measured by the method of Pasztor et al. (Pasztor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM134261(US8846660, 29)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the compounds of the present invention for recombinant human chymase was measured by the method of Pasztor et al. (Pasztor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50094233(CHEMBL3586023)
Affinity DataIC50:  11nMAssay Description:Binding affinity to ghrelin receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096215(CHEMBL3593815)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at ghrelin receptor in Sprague-Dawley rat primary pituitary cells assessed as inhibition of ghrelin-induced growth hormone secret...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096215(CHEMBL3593815)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at rat ghrelin receptor expressed in CHO cells assessed as blocking of human ghrelin-induced response by FLIPR based intracellula...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM50210107(7-chloro-3-(4-chlorophenylsulfonyl)quinazoline-2,4...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM100749(US8507714, 214)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity of the compounds for recombinant human chymase was measured by method of Pasztor et al. (Pasztor et al., Acta Biol. Hung. 42:285-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM100743(US8507714, 67)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity of the compounds for recombinant human chymase was measured by method of Pasztor et al. (Pasztor et al., Acta Biol. Hung. 42:285-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM134272(US8846660, 58)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the compounds of the present invention for recombinant human chymase was measured by the method of Pasztor et al. (Pasztor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM134269(US8846660, 44)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the compounds of the present invention for recombinant human chymase was measured by the method of Pasztor et al. (Pasztor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM134268(US8846660, 42)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the compounds of the present invention for recombinant human chymase was measured by the method of Pasztor et al. (Pasztor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM134253(US8846660, 103 | US8846660, 12)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the compounds of the present invention for recombinant human chymase was measured by the method of Pasztor et al. (Pasztor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM134256(US8846660, 18)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the compounds of the present invention for recombinant human chymase was measured by the method of Pasztor et al. (Pasztor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM134260(US8846660, 27)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the compounds of the present invention for recombinant human chymase was measured by the method of Pasztor et al. (Pasztor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM101748(CHEMBL2057911 | US8530490, 8)
Affinity DataIC50:  21nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM50210098(6-(4,5-dichloro-2-methoxybenzyl)-4-(4-chlorophenyl...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM100752(US8507714, 269)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity of the compounds for recombinant human chymase was measured by method of Pasztor et al. (Pasztor et al., Acta Biol. Hung. 42:285-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50094230(CHEMBL3586026)
Affinity DataIC50:  24nMAssay Description:Binding affinity to ghrelin receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50096214(CHEMBL3593814)
Affinity DataIC50:  26nMAssay Description:Inverse agonist activity rat ghrelin receptor expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM50210116(6-(5-fluoro-2-methoxybenzyl)-4-(4-chlorophenylsulf...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50391352(CHEMBL2147981)
Affinity DataIC50:  26nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 433 total ) | Next | Last >>
Jump to: