TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 0.00400nMAssay Description:Binding affinity of compound against rabbit lung angiotensin I-converting enzyme (ACE) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Compound was tested for inhibition of neutral endopeptidase (NEP).More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Binding affinity of compound against rabbit lung angiotensin I-converting enzyme (ACE) was determinedMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Binding affinity of compound against rabbit lung angiotensin I-converting enzyme (ACE) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Compound was tested for inhibition of neutral endopeptidase (NEP).More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in vitro.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by PDSP Ki Database
Aventis Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 0.600nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by PDSP Ki Database
Aventis Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 0.600nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Hoechst Marion Roussel
Curated by PDSP Ki Database
Hoechst Marion Roussel
Curated by PDSP Ki Database
Affinity DataKi: 1nMAssay Description:Binding affinity towards human Dopamine receptor D4.2 in CHO cellsMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of [3H]- LTB4 binding on human whole cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by PDSP Ki Database
Aventis Pharmaceuticals
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by PDSP Ki Database
Aventis Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 1.30nMAssay Description:Inhibition of human recombinant mTOR by FRET assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Hoechst Marion Roussel
Curated by PDSP Ki Database
Hoechst Marion Roussel
Curated by PDSP Ki Database
Affinity DataKi: 1.40nMAssay Description:Inhibition of human recombinant mTOR by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of human recombinant mTOR by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of human recombinant mTOR by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor (unknown origin) expressed in CHO cell membranes after 60 minsMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Tested for rate of substrate hydrolysis in the presence of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity of compound against rabbit lung angiotensin I-converting enzyme (ACE) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of human recombinant mTOR by FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of human recombinant mTOR by FRET assayMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of [3H]- LTB4 binding on human whole cellsMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of human recombinant mTOR by FRET assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by PDSP Ki Database
Aventis Pharmaceuticals
Curated by PDSP Ki Database
TargetNeutrophil elastase(Homo sapiens (Human))
Marion Merrell Dow Research Institute
Curated by ChEMBL
Marion Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in the presence of pig liver esterase, in vitro.More data for this Ligand-Target Pair