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Found 303 with Last Name = 'przytulinska' and Initial = 'm'
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50365695(CHEMBL1958408)
Affinity DataKi:  0.280nMAssay Description:Inhibition of human Cdc7 using biotin-C6linker-TPSDSLIYDDGLS as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300018(2-(4-(Oxazol-5-yl)phenyl)-1H-benzo[d]imidazole-4-c...)
Affinity DataKi:  0.760nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50426461(CHEMBL2322677)
Affinity DataKi:  0.900nMAssay Description:Inhibition of human Cdc7 using biotin-C6linker-TPSDSLIYDDGLS as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300015(2-(4-(Pyridin-3-yl)phenyl)-1H-benzo[d]imidazole-4-...)
Affinity DataKi:  0.950nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300008(2-(4-(1,3,4-Oxadiazol-2-yl)phenyl)-1H-benzo[d]imid...)
Affinity DataKi:  1nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300019(2-(4-(1H-Imidazol-5-yl)phenyl)-1H-benzo[d]imidazol...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50426464(CHEMBL2322674)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human Cdc7 using biotin-C6linker-TPSDSLIYDDGLS as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300009(2-(4-(5-Oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)pheny...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300021(2-(4-(Thiazol-4-yl)phenyl)-1H-benzo[d]imidazole-4-...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50426467(CHEMBL2322683)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human Cdc7 using biotin-C6linker-TPSDSLIYDDGLS as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300016(2-(4-(Pyridin-2-yl)phenyl)-1H-benzo[d]imidazole-4-...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300017(2-(biphenyl-4-yl)-1H-benzo[d]imidazole-4-carboxami...)
Affinity DataKi:  2nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300020(2-(4-(1H-Imidazol-2-yl)phenyl)-1H-benzo[d]imidazol...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300023(2-(4-(2-Aminothiazol-4-yl)phenyl)-1H-benzo[d]imida...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300022(2-(4-(2-Methyloxazol-4-yl)phenyl)-1H-benzo[d]imida...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26707(7-chloro-9-ethyl-6-hydroxy-1H,3H,4H,9H-quinolino[2...)
Affinity DataKi:  2.5nM ΔG°:  -48.6kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300005(2-(4-(Imidazo[1,2-a]pyridin-2-yl)phenyl)-1H-benzo[...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300014(2-(4-(Pyridin-4-yl)phenyl)-1H-benzimidazole-4-carb...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50426468(CHEMBL2322682)
Affinity DataKi:  3.20nMAssay Description:Inhibition of human Cdc7 using biotin-C6linker-TPSDSLIYDDGLS as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50426466(CHEMBL2322684)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human Cdc7 using biotin-C6linker-TPSDSLIYDDGLS as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300011(2-(4-(5-Thioxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)ph...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300007(2-(4-(3-Methyl-1,2,4-oxadiazol-5-yl)phenyl)-1H-ben...)
Affinity DataKi:  4nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300013(2-(4-(1-Methyl-1H-pyrazol-3-yl)phenyl)-1H-benzo[d]...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27135(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-1,3-benzodiazo...)
Affinity DataKi:  5nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300010(2-(4-(5-Oxo-4,5-dihydro-1,2,4-thiadiazol-3-yl)phen...)
Affinity DataKi:  5.20nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50426463(CHEMBL2322675)
Affinity DataKi:  5.5nMAssay Description:Inhibition of human Cdc7 using biotin-C6linker-TPSDSLIYDDGLS as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300006(2-(4-(7-(Trifluoromethyl)imidazo[1,2-a]pyridin-2-y...)
Affinity DataKi:  6.80nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50426465(CHEMBL2322673)
Affinity DataKi:  7.70nMAssay Description:Inhibition of human Cdc7 using biotin-C6linker-TPSDSLIYDDGLS as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM27119(2-(1-propylpiperidin-4-yl)-1H-1,3-benzodiazole-4-c...)
Affinity DataKi:  8nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50426472(CHEMBL2322678)
Affinity DataKi:  8.70nMAssay Description:Inhibition of human Cdc7 using biotin-C6linker-TPSDSLIYDDGLS as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300012(2-(4-(Isoxazol-5-yl)phenyl)-1H-benzo[d]imidazole-4...)
Affinity DataKi:  10nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26698(7-chloro-6-fluoro-9-(propan-2-yl)-1H,3H,4H,9H-quin...)
Affinity DataKi:  12.3nM ΔG°:  -44.7kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50426471(CHEMBL2322679)
Affinity DataKi:  13nMAssay Description:Inhibition of human Cdc7 using biotin-C6linker-TPSDSLIYDDGLS as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50426470(CHEMBL2322680)
Affinity DataKi:  15nMAssay Description:Inhibition of human Cdc7 using biotin-C6linker-TPSDSLIYDDGLS as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26699(9-butyl-7-chloro-6-fluoro-1H,3H,4H,9H-quinolino[2,...)
Affinity DataKi:  15nM ΔG°:  -44.2kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300025(2-(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)pheny...)
Affinity DataKi:  16nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50300024(2-(4-(1H-Tetrazol-5-yl)phenyl)-1H-benzo[d]imidazol...)
Affinity DataKi:  20nMAssay Description:Inhibition of PARP1 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26697(7-chloro-9-ethyl-6-fluoro-1H,3H,4H,9H-quinolino[2,...)
Affinity DataKi:  21.8nM ΔG°:  -43.3kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50426469(CHEMBL2322681)
Affinity DataKi:  27nMAssay Description:Inhibition of human Cdc7 using biotin-C6linker-TPSDSLIYDDGLS as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26700(9-benzyl-7-chloro-6-fluoro-1H,3H,4H,9H-quinolino[2...)
Affinity DataKi:  36.5nM ΔG°:  -42.0kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26707(7-chloro-9-ethyl-6-hydroxy-1H,3H,4H,9H-quinolino[2...)
Affinity DataKi:  43.5nM ΔG°:  -41.6kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26701(7-chloro-9-ethyl-6-fluoro-1-methyl-1H,3H,4H,9H-qui...)
Affinity DataKi:  50.1nM ΔG°:  -41.2kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50426461(CHEMBL2322677)
Affinity DataKi:  58nMAssay Description:Inhibition of human recombinant GSK3betaMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26698(7-chloro-6-fluoro-9-(propan-2-yl)-1H,3H,4H,9H-quin...)
Affinity DataKi:  62.8nM ΔG°:  -40.7kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50426462(CHEMBL2322676)
Affinity DataKi:  67nMAssay Description:Inhibition of human Cdc7 using biotin-C6linker-TPSDSLIYDDGLS as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26699(9-butyl-7-chloro-6-fluoro-1H,3H,4H,9H-quinolino[2,...)
Affinity DataKi:  165nM ΔG°:  -38.3kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26697(7-chloro-9-ethyl-6-fluoro-1H,3H,4H,9H-quinolino[2,...)
Affinity DataKi:  174nM ΔG°:  -38.2kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26703(7-chloro-9-ethyl-6-fluoro-1-[(3-hydroxyphenyl)meth...)
Affinity DataKi:  271nM ΔG°:  -37.1kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26700(9-benzyl-7-chloro-6-fluoro-1H,3H,4H,9H-quinolino[2...)
Affinity DataKi:  558nM ΔG°:  -35.3kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26705(7-chloro-9-ethyl-6-fluoro-1-(2-hydroxyethyl)-1H,3H...)
Affinity DataKi:  1.16E+3nM ΔG°:  -33.5kJ/molepH: 7.5 T: 2°CAssay Description:Assays were conducted in 384-well v-bottom polypropylene plates. Test compound was mixed with Pim and biotinylated peptide substrate, followed by imm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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