Affinity DataKi: 6nMAssay Description:His-tagged human RAR-related orphan receptor alpha (hRORa), human RAR-related orphan receptor beta (hRORb), and human RAR-related orphan receptor gam...More data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:His-tagged human RAR-related orphan receptor alpha (hRORa), human RAR-related orphan receptor beta (hRORb), and human RAR-related orphan receptor gam...More data for this Ligand-Target Pair
Affinity DataKi: 6.96nMAssay Description:His-tagged human RAR-related orphan receptor alpha (hRORa), human RAR-related orphan receptor beta (hRORb), and human RAR-related orphan receptor gam...More data for this Ligand-Target Pair
Affinity DataKi: 3.16E+3nMAssay Description:Binding affinity to 5HT2B receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.46E+3nMAssay Description:His-tagged human RAR-related orphan receptor alpha (hRORa), human RAR-related orphan receptor beta (hRORb), and human RAR-related orphan receptor gam...More data for this Ligand-Target Pair
Affinity DataKi: 5.68E+3nMAssay Description:His-tagged human RAR-related orphan receptor alpha (hRORa), human RAR-related orphan receptor beta (hRORb), and human RAR-related orphan receptor gam...More data for this Ligand-Target Pair
Affinity DataKi: >1.25E+4nMAssay Description:His-tagged human RAR-related orphan receptor alpha (hRORa), human RAR-related orphan receptor beta (hRORb), and human RAR-related orphan receptor gam...More data for this Ligand-Target Pair
Affinity DataKi: >1.25E+4nMAssay Description:His-tagged human RAR-related orphan receptor alpha (hRORa), human RAR-related orphan receptor beta (hRORb), and human RAR-related orphan receptor gam...More data for this Ligand-Target Pair
Affinity DataKi: >1.25E+4nMAssay Description:His-tagged human RAR-related orphan receptor alpha (hRORa), human RAR-related orphan receptor beta (hRORb), and human RAR-related orphan receptor gam...More data for this Ligand-Target Pair
Affinity DataKi: >2.04E+4nMAssay Description:His-tagged human RAR-related orphan receptor alpha (hRORa), human RAR-related orphan receptor beta (hRORb), and human RAR-related orphan receptor gam...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Negative allosteric modulation of human recombinant mGlu1 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Negative allosteric modulation of human recombinant mGlu5 receptor expressed in Syrian hamster AV12 cells assessed as receptor-mediated changes in in...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair