TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 3.80E+3nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 4.10E+3nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 4.40E+3nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 8.30E+3nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 1.30E+4nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 1.90E+4nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 2.40E+4nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 3.40E+4nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >3.60E+4nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >4.00E+4nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >4.00E+4nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >4.00E+4nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >4.00E+4nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 4.00E+4nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: >4.00E+4nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 6.30E+4nMAssay Description:Binding affinity to human ERG by dofetilide fluorescence polarization binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.108nMAssay Description:Inhibition of rabbit F10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.32nMAssay Description:Inhibition of rat F10aMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human Factor-10aMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrat...More data for this Ligand-Target Pair