Affinity DataKi: 0.0140nMAssay Description:The compound was evaluated for its binding affinity towards human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Antagonist activity at human mu opioid receptor by GTP-gamma S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nM Kon: 4.90M-1s-1 Koff: 3.05E+4s-1Assay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:The compound was evaluated for its binding affinity towards human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Antagonist activity at human mu opioid receptor by GTP-gamma S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:The compound was evaluated for its binding affinity towards human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataKi: 0.310nM Kon: 0.00000207M-1s-1 Koff: 6.63E+3s-1Assay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.810nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:The compound was evaluated for its binding affinity towards human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataKi: 1.73nM Kon: 0.0000109M-1s-1 Koff: 6.31E+3s-1Assay Description:The compound was evaluated for its inhibitory activity against human neutrophil elastase (HNE) using whole blood assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -50.5kJ/moleT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Antagonist activity at human mu opioid receptor by GTP-gamma S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Antagonist activity at human mu opioid receptor by GTP-gamma S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -48.7kJ/molepH: 7.2 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 7.60nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 8.20nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 9.20nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 9.20nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 9.40nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 9.70nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 20nM ΔG°: -44.7kJ/moleT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair