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Found 4 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A2a' and Ligand = 'BDBM50266416'
TargetAdenosine receptor A2a(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50266416(CHEMBL458224 | N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50266416(CHEMBL458224 | N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50266416(CHEMBL458224 | N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]ZM241385 from rat adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50266416(CHEMBL458224 | N-[2-(3,5-Dimethylpyrazol-1-yl)-6-(...)
Affinity DataIC50:  85nMAssay Description:Antagonist activity at human adenosine A2A receptor assessed as inhibition of CGS-21680-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed