Found 7 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha' and Ligand = 'BDBM50087812' TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.80E+3nMAssay Description:Displacement of FITC-geldanamycin from human HSP90alpha at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of human recombinant HSP90alpha expressed in Escherichia coli by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.32E+4nMAssay Description:Displacement of FITC-geldanamycin from human HSP90alpha at 277 K after 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Displacement of Cy3B-GM from recombinant Hsp90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Affinity DataKd: 620nMAssay Description:Inhibition of FITC-geldanamycin binding to HSP90alpha (unknown origin) incubated for 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Affinity DataKd: 620nMAssay Description:Binding affinity to human N-terminal 6His-tagged HSP90alpha (1 to 236 residues) expressed in Escherichia coli BL21star/Rosetta2 (DE3) at 298 K by ITC...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Hauptman-Woodward Medical Research Institute
Curated by ChEMBL
Affinity DataKd: 1.31E+4nMAssay Description:Apparent binding affinity to Hsp90alpha (unknown origin) after 24 hrs by fluorescence polarization assay using FITC-GDA as tracerMore data for this Ligand-Target Pair
