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Found 7 Enz. Inhib. hit(s) with Target = 'Histamine H2 receptor' and Ligand = 'BDBM50403559'
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Missouri

Curated by ChEMBL
LigandPNGBDBM50403559(Brumetadina | CIMETIDINE)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]Cimetidine from histamine H2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Missouri

Curated by ChEMBL
LigandPNGBDBM50403559(Brumetadina | CIMETIDINE)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]Cimetidine from histamine H2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Missouri

Curated by ChEMBL
LigandPNGBDBM50403559(Brumetadina | CIMETIDINE)
Affinity DataKi:  140nMAssay Description:Binding affinity to human histamine H2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50403559(Brumetadina | CIMETIDINE)
Affinity DataKi:  501nMAssay Description:Evaluated in vitro for Histamine H2 receptor inhibition using the dimaprit stimulated chronotropic response of the guinea pig atriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50403559(Brumetadina | CIMETIDINE)
Affinity DataKi:  501nMAssay Description:In vitro inhibition of Histamine H2 receptor by measuring its ability to block the histamine-stimulated adenylate cyclase of guinea pig hippocampal h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Missouri

Curated by ChEMBL
LigandPNGBDBM50403559(Brumetadina | CIMETIDINE)
Affinity DataIC50:  140nMAssay Description:Binding affinity to human histamine H2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Missouri

Curated by ChEMBL
LigandPNGBDBM50403559(Brumetadina | CIMETIDINE)
Affinity DataIC50:  270nMAssay Description:Binding affinity to human histamine H2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed