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Found 4 Enz. Inhib. hit(s) with Target = 'Pro-cathepsin H' and Ligand = 'BDBM453289'
TargetPro-cathepsin H(Homo sapiens (Human))
Cortexyme

US Patent
LigandPNGBDBM453289(US10730826, Compound 2a | US11325884, Compound 2a)
Affinity DataIC50:  1.55E+3nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPro-cathepsin H(Homo sapiens (Human))
Cortexyme

US Patent
LigandPNGBDBM453289(US10730826, Compound 2a | US11325884, Compound 2a)
Affinity DataIC50:  1.55E+3nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPro-cathepsin H(Homo sapiens (Human))
Cortexyme

US Patent
LigandPNGBDBM453289(US10730826, Compound 2a | US11325884, Compound 2a)
Affinity DataIC50:  1.55E+3nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of cathepsins B, H, K, L, and S were measured in similar assays. Boc-Leu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPro-cathepsin H(Homo sapiens (Human))
Cortexyme

US Patent
LigandPNGBDBM453289(US10730826, Compound 2a | US11325884, Compound 2a)
Affinity DataIC50:  1.55E+3nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent