Found 7 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1' and Ligand = 'BDBM50376383' TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Okayama University Graduate School Of Medicine
Curated by ChEMBL
Okayama University Graduate School Of Medicine
Curated by ChEMBL
3D Structure (crystal)TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Okayama University Graduate School Of Medicine
Curated by ChEMBL
Okayama University Graduate School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of PGH2 production using arachidonic acid as substrate by TMPD oxidation based colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ovine COX1 catalytic activity using arachidonic acid as substrate preincubated for 5 mins followed by substrate and hemin addition meas...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Okayama University Graduate School Of Medicine
Curated by ChEMBL
Okayama University Graduate School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human COX1 assessed as reduction in appearance of oxidized TMPD using arachidonic acid as substrate by colorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
