Found 9 Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 7' and Ligand = 'BDBM50465231'
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human USP7 using Ub-Rho110 as substrate by SPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of USP7 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of full-length USP7 (unknown origin) using ubiquitin-rhodamine 110 as substrate preincubated for 30 mins followed by substrate addition an...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged full length USP7 expressed in baculovirus infected Sf21 cells using monoubiquitinated ubiquiti...More data for this Ligand-Target Pair
Affinity DataIC50: <250nMAssay Description:USP7 activity was monitored in a fluorescence polarisation (FP) homogeneous assay using the isopeptide ubiquitin-Lys-TAMRA substrate (U-558, Boston B...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human USP7 using Ub-Rho110 as substrate by fluorescence based SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 42nMAssay Description:Binding affinity to USP7 (208 to 560 residues) (unknown origin) assessed as dissociation constant by biolayer interferometryMore data for this Ligand-Target Pair
Affinity DataKd: 53nMAssay Description:Binding affinity to human USP7 (208 to 560 residues) by SPR methodMore data for this Ligand-Target Pair
Affinity DataKd: 4.71E+5nMAssay Description:Inhibition of human USP7 using Ub-Rho110 as substrate assessed as dissociation constant by fluorescence based SPR analysisMore data for this Ligand-Target Pair