Found 105 Enz. Inhib. hit(s) with all data for entry = 50004459 Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.00145nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0427nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0525nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0537nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0646nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0741nMAssay Description:Antagonistic activity at human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.102nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.107nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.141nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.195nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.234nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.339nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.339nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.759nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 0.813nMAssay Description:Antagonistic activity at human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 107nMAssay Description:Antagonistic activity at human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 316nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 398nMAssay Description:Binding affinity to opioid receptor Sigma1More data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nMAssay Description:Binding affinity to alpha2B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nMAssay Description:Binding affinity to Histamine receptor H1More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 2.51E+3nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 2.51E+3nMAssay Description:Binding affinity to muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 3.16E+3nMAssay Description:Binding affinity to 5HT1D receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.16E+3nMAssay Description:Binding affinity to Histamine receptor H2More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 3.63E+3nMAssay Description:Antagonistic activity at human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: 6.31E+3nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5HT1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5HT1E receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5HT5A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Drug Discovery Laboratory
Curated by ChEMBL
Drug Discovery Laboratory
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5HT7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to alpha1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to alpha2B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to beta1 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to beta3 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to dopamine receptor D3More data for this Ligand-Target Pair
