Compile Data Set for Download or QSAR
maximum 50k data
Found 29 Enz. Inhib. hit(s) with all data for entry = 50021099
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220966(1-[(3R,3aR)-8-fluoro-3-(3-morpholin-4-yl-propyl)-3...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220958(1-[(3R,3aR)-3-(3-amino-propyl)-8-fluoro-3-phenyl-3...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220964(1-[3-((3R,3aR)-2-acetyl-8-fluoro-3-phenyl-3a,4-dih...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220969(1-{(3R,3aR)-3-[3-(4-acetyl-piperazin-1-yl)-propyl]...)
Affinity DataIC50:  1nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220967(1-[(3R,3aR)-8-chloro-3-(3-dimethylamino-propyl)-3-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220970(1-[(3R,3aR)-8-methyl-3-(3-morpholin-4-yl-propyl)-3...)
Affinity DataIC50:  1nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220963(1-[3-((3R,3aR)-2-acetyl-8-fluoro-3-phenyl-3a,4-dih...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220960(1-[(3R,3aR)-3-(3-dimethylamino-propyl)-8-fluoro-3-...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM24104(1-[(5R,6R)-5-[3-(4-acetylpiperazin-1-yl)propyl]-12...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220957(1-[(3R,3aR)-3-(3-dimethylamino-propyl)-8-methyl-3-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220959(1-[(R)-8-chloro-3-(3-morpholin-4-yl-propyl)-3-phen...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220971(1-[(R)-4-[3-(4-acetyl-piperazin-1-yl)-propyl]-1-(2...)
Affinity DataIC50:  3nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220962(1-[(3R,3aR)-8-fluoro-3-phenyl-3-(3-piperazin-1-yl-...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220961(1-[(3R,3aR)-8-fluoro-3-(3-hydroxy-propyl)-3-phenyl...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220968(1-((3R,3aR)-8-fluoro-3-phenyl-3a,4-dihydro-3H-5-ox...)
Affinity DataIC50:  155nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220965(1-((3R,3aR)-3-phenyl-3a,4-dihydro-3H-5-oxa-1,9b-di...)
Affinity DataIC50:  800nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220958(1-[(3R,3aR)-3-(3-amino-propyl)-8-fluoro-3-phenyl-3...)
Affinity DataIC50:  940nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220967(1-[(3R,3aR)-8-chloro-3-(3-dimethylamino-propyl)-3-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220957(1-[(3R,3aR)-3-(3-dimethylamino-propyl)-8-methyl-3-...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220959(1-[(R)-8-chloro-3-(3-morpholin-4-yl-propyl)-3-phen...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220962(1-[(3R,3aR)-8-fluoro-3-phenyl-3-(3-piperazin-1-yl-...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220969(1-{(3R,3aR)-3-[3-(4-acetyl-piperazin-1-yl)-propyl]...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220960(1-[(3R,3aR)-3-(3-dimethylamino-propyl)-8-fluoro-3-...)
Affinity DataIC50:  5.94E+3nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220966(1-[(3R,3aR)-8-fluoro-3-(3-morpholin-4-yl-propyl)-3...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220970(1-[(3R,3aR)-8-methyl-3-(3-morpholin-4-yl-propyl)-3...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220964(1-[3-((3R,3aR)-2-acetyl-8-fluoro-3-phenyl-3a,4-dih...)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM24104(1-[(5R,6R)-5-[3-(4-acetylpiperazin-1-yl)propyl]-12...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220963(1-[3-((3R,3aR)-2-acetyl-8-fluoro-3-phenyl-3a,4-dih...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220961(1-[(3R,3aR)-8-fluoro-3-(3-hydroxy-propyl)-3-phenyl...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed