Compile Data Set for Download or QSAR
Report error Found 1374 of affinity data for UniProtKB/TrEMBL: P52732
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23773((2R)-2-amino-3-[(diphenylmethyl)sulfanyl]propanoic...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23782((chlorodiphenylmethyl)benzene | Triphenylmethyl-co...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23783((bromodiphenylmethyl)benzene | Triphenylmethyl-con...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23784(CHEMBL118166 | triphenylmethanol | Triphenylmethyl...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23785((methoxydiphenylmethyl)benzene | Triphenylmethyl-c...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23786(triphenylmethanamine | Triphenylmethyl-containing ...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23787((1,1-diphenylethyl)benzene | Triphenylmethyl-conta...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23788((1,1-diphenylpropyl)benzene | Triphenylmethyl-cont...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23789(2-methyl-4,4,4-triphenylbutan-2-ol | Triphenylmeth...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23790(4-(triphenylmethyl)aniline | p-Tritylaniline | Tri...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23791(triphenylmethanethiol | Triphenylmethyl-containing...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23792([(ethylsulfanyl)diphenylmethyl]benzene | Triphenyl...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23793([(benzylsulfanyl)diphenylmethyl]benzene | Tripheny...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23794(1-[(triphenylmethyl)sulfanyl]ethan-1-one | Triphen...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23795({[(2-chloroethyl)sulfanyl]diphenylmethyl}benzene |...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23796(4-[(triphenylmethyl)sulfanyl]butan-2-one | Triphen...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23797(2-[(triphenylmethyl)sulfanyl]ethan-1-ol | Tripheny...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23798(1-methyl-2-[(triphenylmethyl)sulfanyl]benzene | Tr...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23800(methyl 2-[(triphenylmethyl)sulfanyl]acetate | Trip...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23801(methyl 3-[(triphenylmethyl)sulfanyl]propanoate | T...)
Affinity DatapH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23803(3-[(triphenylmethyl)sulfanyl]propan-1-amine | Trip...)
Affinity DataT: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23804(4-[(triphenylmethyl)sulfanyl]butan-1-amine | Triph...)
Affinity DataT: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23806(3-[(triphenylmethyl)sulfanyl]propanoic acid | Trip...)
Affinity DataT: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23807(2-[(E)-(thiophen-2-ylmethylidene)amino]-3-[(triphe...)
Affinity DataT: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23808(CHEMBL415259 | (2R)-2-acetamido-3-[(triphenylmethy...)
Affinity DataT: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23809(CHEMBL398146 | N,S-ditrityl-L-cysteine | (2R)-2-[(...)
Affinity DataT: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23810(2-[(diphenylmethyl)amino]-3-[(triphenylmethyl)sulf...)
Affinity DataT: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23811(CHEMBL232727 | (2R)-2-{[(tert-butoxy)carbonyl]amin...)
Affinity DataT: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23834(cid_276215 | (2R)-2-amino-3-{[9-(4-chlorophenyl)-9...)
Affinity DataT: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23835((2R)-2-acetamido-3-[(9-phenyl-9H-fluoren-9-yl)sulf...)
Affinity DataT: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM50293756(KSP Inhibitor, 4a | CHEMBL561696 | 2-(4-(methylthi...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM50293753(KSP Inhibitor, 4b | CHEMBL565195 | 2-(4-(methylsul...)
Affinity DataKd:  2.50E+3nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM92864(KSP Inhibitor, 4c)
Affinity DataKd:  1.40E+4nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM92865(KSP Inhibitor, 4d)
Affinity DataKd:  5.00E+3nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM50293744(KSP Inhibitor, 4e | CHEMBL563643 | 2-(4-sulfamoylp...)
Affinity DataKd:  600nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM50293759(CHEMBL563846 | KSP Inhibitor, 4f | 2-(4-methoxyphe...)
Affinity DataKd:  1.20E+3nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM92866(KSP Inhibitor, 4g)
Affinity DataKd:  3.40E+3nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM50468755(CHEMBL4283764)
Affinity DataKd:  220nMAssay Description:Binding affinity to N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by isothermal titratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM50431886(CHEMBL1413473)
Affinity DataKd:  665nMAssay Description:Binding affinity to N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by isothermal titratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM50351253(CHEMBL1818528)
Affinity DataEC50:  160nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM50351254(CHEMBL1818529)
Affinity DataEC50:  115nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23772(STLC | Tritylcysteine | 3-Tritylthio-L-alanine | N...)
Affinity DataEC50:  1.72E+3nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM23823((2R)-2-amino-3-{[(4-methoxyphenyl)diphenylmethyl]s...)
Affinity DataEC50:  230nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM50351255(CHEMBL1818525)
Affinity DataEC50:  600nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM50351256(CHEMBL1818526)
Affinity DataEC50:  294nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM50351257(CHEMBL1818527)
Affinity DataEC50:  190nMAssay Description:Inhibition of KSP in human HeLa cells assessed as bipolar spindle formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM50382546(CHEMBL2022996)
Affinity DataEC50:  73nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM50382582(CHEMBL2022999)
Affinity DataEC50:  95nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM50427294(SB-743921 | CHEMBL2325429)
Affinity DataKd: >10nMAssay Description:Binding affinity to human wild type Eg5 at 250 uM by isothermal calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
Institut De Biologie Structurale

LigandPNGBDBM50068357(CHEMBL3402343)
Affinity DataEC50:  452nMAssay Description:Inhibition of KSP in human HCT116 cells assessed as phos-histone H3 level by immunofluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
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