Affinity DataKi: 1.45nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.45nM ΔG°: -50.4kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 1.55nMAssay Description:Binding affinity to rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Binding affinity of compound towards rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nM ΔG°: -49.0kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
Affinity DataKi: 2.63nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.69nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nM ΔG°: -48.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 2.70nM ΔG°: -48.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 3.24nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Binding affinity of compound towards rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nM ΔG°: -48.3kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 3.60nM ΔG°: -48.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 3.80nM ΔG°: -48.1kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 4.27nMAssay Description:Displacement of [3H]-histamine from rat H4R expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.47nMAssay Description:Displacement of [3H]-histamine from rat histamine H4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nM ΔG°: -47.6kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 4.70nM ΔG°: -47.5kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 4.80nM ΔG°: -47.5kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 5.10nM ΔG°: -47.3kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 5.40nM ΔG°: -47.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity to rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.60nM ΔG°: -46.3kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 9.20nM ΔG°: -45.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]histamine from rat histamine H4 receptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 12.3nMAssay Description:Displacement of [3H]-histamine from rat H4R expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 14nM ΔG°: -44.8kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 15.8nMAssay Description:Binding affinity to rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity to rat histamine H4 receptor expressed in human SK-N-MC cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity to rat histamine H4 receptor expressed in human SK-N-MC cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 24.6nMAssay Description:Binding affinity to rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Binding affinity to rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Binding affinity to rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 50.1nMAssay Description:Binding affinity to rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Binding affinity to rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Binding affinity to rat histamine H4 receptor expressed in human SK-N-MC cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 71nMAssay Description:Binding affinity to rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Binding affinity to rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 136nMAssay Description:Binding affinity to rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 138nMAssay Description:Binding affinity to rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 174nMAssay Description:Displacement of [3H]histamine from rat H4RMore data for this Ligand-Target Pair
Affinity DataKi: 188nMAssay Description:Displacement of [3H]histamine from rat recombinant histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 188nMAssay Description:Displacement of [3H]histamine from rat histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysisMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Binding affinity to rat histamine H4 receptor expressed in human SK-N-MC cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 275nM ΔG°: -37.4kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 275nM ΔG°: -37.4kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 316nMAssay Description:Binding affinity to rat histamine H4 receptor expressed in human SK-N-MC cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 339nM ΔG°: -36.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Affinity DataKi: 339nM ΔG°: -36.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
