BDBM50204290 CHEMBL3979920::US11077111, Compound IIIa::US20230295171, Example 102

SMILES: Cn1cc(cn1)c2c3c(c(c(n2)N[C@@H]4CCCC[C@@H]4N)F)CNC3=O

InChI Key: InChIKey=MJHOMTRKVMKCNE-UHFFFAOYSA-N

Data: 20 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50204290   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PAK 4 (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ZAP-70 (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	226	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Fer (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
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Interleukin 1 receptor associated kinase 4 (Dog)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17.7	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	n/a
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Ephrin type-A receptor 1 (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.80	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.98	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.51	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase (Red fox)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase (Dog)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase (Dog)	BDBM50204290 (CHEMBL3979920 | US11077111, Compound IIIa | US2023...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
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