Compile Data Set for Download or QSAR
maximum 50k data
Found 265 of ec50 data for polymerid = 50000160,50001011,50001090,50001091
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50171900((S)-3-Phenyl-2-(4-thiophen-2-yl-phenoxy)-propionic...)
Affinity DataEC50:  0.150nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM28759((2S)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | ...)
Affinity DataEC50:  0.200nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50171898((S)-3-Phenyl-2-(4-trifluoromethyl-phenoxy)-propion...)
Affinity DataEC50:  0.270nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50171895((2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid | (...)
Affinity DataEC50:  0.350nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293851((2R)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  0.550nMAssay Description:Agonist activity at dog PPARalpha receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171996(2-Ethyl-5-[3-(2-propyl-4-trifluoromethylsulfanyl-p...)
Affinity DataEC50: <1nMAssay Description:Binding affinity of compound towards Factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172004((S)-5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethyl)-pheno...)
Affinity DataEC50: <1nMAssay Description:In vitro inhibitory activity against Factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172002(6-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-propoxy...)
Affinity DataEC50: <1nMAssay Description:In vitro inhibitory activity against Factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171993(5-[3-(2-Chloro-4-trifluoromethylsulfanyl-phenoxy)-...)
Affinity DataEC50: <1nMAssay Description:In vitro inhibitory activity against Factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172003((R)-5-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-pro...)
Affinity DataEC50: <1nMAssay Description:In vitro inhibitory activity against Factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50099491(2-(4-(2-(3-cyclohexyl-1-(4-cyclohexylbutyl)ureido)...)
Affinity DataEC50:  1nMAssay Description:Activation of murine PPAR alpha ligand binding domainMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50171897((2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid | ...)
Affinity DataEC50:  1.30nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171988((S)-5-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-pro...)
Affinity DataEC50:  2nMAssay Description:Effective concentration against canine PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50229206(CHEMBL253310 | N-(4-(trifluoromethylsulfonamido)be...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171997(5-{3-[2-Chloro-4-(2,2-dimethyl-propyl)-phenoxy]-pr...)
Affinity DataEC50:  2nMAssay Description:Effective concentration against canine PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171992((S)-5-{3-[2-Chloro-4-(3,3,3-trifluoro-propyl)-phen...)
Affinity DataEC50:  2nMAssay Description:Effective concentration against canine PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172006(2-tert-Butyl-5-{3-[2-chloro-4-(2,2,2-trifluoro-eth...)
Affinity DataEC50:  2nMAssay Description:Effective concentration against canine PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Rattus norvegicus)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50227669((R)-2-(2-(1-ethyl-3-(4-(trifluoromethoxy)phenyl)ur...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at rat PPARalpha in rat H4IIE cells assessed as gene inductionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50568100(CHEMBL4861761)
Affinity DataEC50:  3nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50568096(CHEMBL4866115)
Affinity DataEC50:  3nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM28799(2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...)
Affinity DataEC50:  5nMAssay Description:Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM28799(2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...)
Affinity DataEC50:  5nMAssay Description:Agonist activity for murine PPAR alpha receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171985(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]...)
Affinity DataEC50:  8nMAssay Description:Effective concentration against canine PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171995((R)-5-[2-(2-Chloro-4-trifluoromethoxy-phenoxy)-eth...)
Affinity DataEC50:  10nMAssay Description:Effective concentration against canine PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM28799(2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)a...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at Gal4-fused mouse PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50568102(CHEMBL4847453)
Affinity DataEC50:  10nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50568097(CHEMBL4879102)
Affinity DataEC50:  10nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50081223(2-(4-{2-[3-(2,4-Difluoro-phenyl)-1-heptyl-ureido]-...)
Affinity DataEC50:  10nMAssay Description:Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50584465(CHEMBL5084377)
Affinity DataEC50:  17nMAssay Description:Agonist activity at mouse PPARalpha transfected in Cos7 cells co-expressing with pBIND and pGL4.35 Gal4 UAS Luc reporter plasmid by measuring lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171991(5-[3-(4-tert-Butyl-2-chloro-phenoxy)-propoxy]-2-et...)
Affinity DataEC50:  20nMAssay Description:Effective concentration against canine PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM28706(2-methyl-2-phenoxypropanoic acid, 25a | 2-methyl-2...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50568103(CHEMBL4847989)
Affinity DataEC50:  20nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50568098(CHEMBL4877444)
Affinity DataEC50:  20nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50568099(CHEMBL4855604)
Affinity DataEC50:  20nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50319262(2-(4-(((2-(2,4-dimethylphenylamino)-2-oxoethyl)(fu...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at Gal4-fused mouse PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50229219(4'-chloro-biphenyl-4-carboxylic acid 4-trifluorome...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at mouse PPARalpha assessed as receptor activation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Rattus norvegicus)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50227674(2-(2-(1-ethyl-3-(4-(trifluoromethylthio)phenyl)ure...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at rat PPARalpha in rat H4IIE cells assessed as gene inductionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172000(5-{3-[2-Chloro-4-(2,2,2-trifluoro-ethyl)-phenoxy]-...)
Affinity DataEC50:  26nMAssay Description:Effective concentration against canine PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50244809((2R)-2-[3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50568101(CHEMBL4870407)
Affinity DataEC50:  30nMAssay Description:Agonist activity at Gal4-fused mouse PPARalpha co-expressed with RXRalpha in monkey CV1 cells assessed as PPRE transcriptional activation incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50373907(CHEMBL271394)
Affinity DataEC50:  30nMAssay Description:Agonist activity at mouse PPARalpha expressed in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50225835((2s,5s)-2-methyl-5-(4-(5-methyl-2-p-tolyloxazol-4-...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at mouse PPARalpha expressed in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Rattus norvegicus)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50227656(2-(2-(1-ethyl-3-(4-isopropylphenyl)ureido)-2,3-dih...)
Affinity DataEC50:  32nMAssay Description:Agonist activity at rat PPARalpha in rat H4IIE cells assessed as gene inductionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Rattus norvegicus)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50227664(2-(2-(1-ethyl-3-(4-(trifluoromethoxy)phenyl)ureido...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at rat PPARalpha in rat H4IIE cells assessed as gene inductionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50081225(2-(4-{2-[3-(4-Fluoro-phenyl)-1-heptyl-ureido]-ethy...)
Affinity DataEC50:  33nMAssay Description:Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM50293847((2R)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM24566(2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...)
Affinity DataEC50:  40nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM24566(2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...)
Affinity DataEC50:  40nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Università

Curated by ChEMBL
LigandPNGBDBM28699(2-(4-chlorophenoxy)-2-methylpropanoic acid | CHEMB...)
Affinity DataEC50:  42nMAssay Description:Effective concentration against murine PPARalpha in transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Canis familiaris)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50171994((R)-5-[3-(2-Chloro-5-trifluoromethyl-phenoxy)-prop...)
Affinity DataEC50:  42nMAssay Description:Effective concentration against canine PPAR-alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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