Affinity DataEC50: 0.0617nMAssay Description:Agonist activity at human melanocortin receptor 3 expressed in human T-REx-293 cells assessed as stimulation of intracellular cAMP accumulation incub...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0617nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0630nMAssay Description:Evaluated for agonist activity at cloned Melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: <0.100nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: <0.100nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: <0.100nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: <0.100nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: <0.100nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: <0.100nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: <0.100nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: <0.100nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: <0.100nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: <0.100nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as stimulation of intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 0.105nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.107nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.130nMAssay Description:Effective concentration required for the biological activity against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.132nMAssay Description:Evaluated for agonist activity at cloned Melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.151nMAssay Description:Agonist activity at human melanocortin receptor 3 expressed in human T-REx-293 cells assessed as stimulation of intracellular cAMP accumulation incub...More data for this Ligand-Target Pair
Affinity DataEC50: 0.151nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.158nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.182nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.191nMAssay Description:Evaluated for agonist activity at cloned Melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.204nMAssay Description:Agonist activity at human MC3R expressed in low doxycyclin-treated HEK293 cell membranes assessed as increase in cAMP production after 45 mins by HTR...More data for this Ligand-Target Pair
Affinity DataEC50: 0.229nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.240nMAssay Description:Effective concentration required for intracellular cAMP accumulation against Melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.240nMAssay Description:Effective concentration that was able to generate 50% maximal intracellular cAMP in L-cells transfected with Melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.270nMAssay Description:Effective concentration required for the biological activity against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.275nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.302nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.309nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.330nMAssay Description:Effective concentration for intracellular cAMP accumulation in human melanocortin 3 receptor expressing HEK 293 cells; (N = 4)More data for this Ligand-Target Pair
Affinity DataEC50: 0.330nMAssay Description:Effective concentration required for intracellular cAMP accumulation against Melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.331nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.347nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.360nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)More data for this Ligand-Target Pair
Affinity DataEC50: 0.360nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.398nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:Agonist activity at human MC3RMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at human MC3RMore data for this Ligand-Target Pair
Affinity DataEC50: 0.603nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.669nMAssay Description:Evaluated for agonist activity at cloned Melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.670nMAssay Description:Effective concentration required for the biological activity against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.676nMAssay Description:Agonist activity at human melanocortin receptor 3 expressed in human T-REx-293 cells assessed as stimulation of intracellular cAMP accumulation incub...More data for this Ligand-Target Pair
Affinity DataEC50: 0.676nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.680nMAssay Description:Agonist activity at human Melanocortin-3 receptor as peptide required for 50% maximal cAMP releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 0.692nMAssay Description:Agonist activity at human MC3R expressed in HEK2936E cells assessed as cAMP production in presence of IBMX by time resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.692nMAssay Description:Agonist activity at human MC3R expressed in low doxycyclin-treated HEK293 cell membranes assessed as increase in cAMP production after 45 mins by HTR...More data for this Ligand-Target Pair
Affinity DataEC50: 0.800nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.800nMAssay Description:Effective concentration for intracellular cAMP accumulation in human melanocortin 3 receptor expressing HEK 293 cells; (N = 4)More data for this Ligand-Target Pair