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Found 74 with Last Name = 'mugrage' and Initial = 'b'
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50280989(2,6-dimethyl-5-methyloxycarbonyl-4-(3-nitrophenyl)...)
Affinity DataIC50:  16nMAssay Description:Tested for its ability to inhibit the binding of [125I]-ET-1 to the Endothelin A receptor in porcine thoracic aorta membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM123744(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50206156(CHEMBL246240 | N-(2-(4-(2-oxo-2,3-dihydrobenzo[d]i...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50280989(2,6-dimethyl-5-methyloxycarbonyl-4-(3-nitrophenyl)...)
Affinity DataIC50:  295nMAssay Description:Tested for its ability to inhibit the binding of [125I]-ET-1 to the Endothelin B receptor in rat cerebellum membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50280990(2,6-dimethyl-5-methyloxycarbonyl-4-(3-nitrophenyl)...)
Affinity DataIC50:  422nMAssay Description:Tested for its inhibitory activity against Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280989(2,6-dimethyl-5-methyloxycarbonyl-4-(3-nitrophenyl)...)
Affinity DataIC50:  592nMAssay Description:Inhibition of [3H]PN-200-110 binding to L-type calcium channels in rat cortex membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50206153(CHEMBL246032 | N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50:  600nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50206155(CHEMBL246031 | N-(2-(4-(2-oxo-2,3-dihydrobenzo[d]i...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50206159(4-fluoro-N-(2-(4-(2-oxo-2,3-dihydrobenzo[d]imidazo...)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156655(US9023354, AD4-10315)
Affinity DataIC50:  1.50E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50206160(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50206154(CHEMBL245623 | N-(2-(4-(2-oxo-2,3-dihydrobenzo[d]i...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50206157(CHEMBL398568 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156660(US9023354, AD4-10963)
Affinity DataIC50:  2.00E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelin receptor type B(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50280990(2,6-dimethyl-5-methyloxycarbonyl-4-(3-nitrophenyl)...)
Affinity DataIC50:  2.70E+3nMAssay Description:Tested for its inhibitory activity against Endothelin B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50447144(CHEMBL3112895 | US9023354, AD4-12917)
Affinity DataIC50:  3.60E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47305(BDBM156659 | US9023354, AD4-10483)
Affinity DataIC50:  4.00E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156422(US9023354, AD4-12909)
Affinity DataIC50:  4.20E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156414(US9023354, AD4-1505)
Affinity DataIC50:  4.20E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156419(US9023354, AD4-12906)
Affinity DataIC50:  4.40E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47305(BDBM156659 | US9023354, AD4-10483)
Affinity DataIC50:  4.60E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156430(US9023354, AD4-12918)
Affinity DataIC50:  5.20E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156506(US9023354, AD4-13080)
Affinity DataIC50:  6.00E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156654(US9023354, AD4-10484)
Affinity DataIC50:  7.40E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156423(US9023354, AD4-12910)
Affinity DataIC50:  7.50E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156492(US9023354, AD4-13067)
Affinity DataIC50:  8.00E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156495(US9023354, AD4-13070)
Affinity DataIC50:  8.00E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47310(US9023354, AD4-13243)
Affinity DataIC50:  8.50E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156479(US9023354, AD4-13054)
Affinity DataIC50:  9.00E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156540(US9023354, AD4-13113)
Affinity DataIC50:  9.00E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156420(US9023354, AD4-12907)
Affinity DataIC50:  9.20E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156415(US9023354, AD4-12902)
Affinity DataIC50:  9.40E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156626(US9023354, AD4-13202)
Affinity DataIC50:  1.00E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156527(US9023354, AD4-13099)
Affinity DataIC50:  1.00E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156620(US9023354, AD4-13196)
Affinity DataIC50:  1.00E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156478(US9023354, AD4-13053)
Affinity DataIC50:  1.20E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156543(US9023354, AD4-13116)
Affinity DataIC50:  1.30E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156632(US9023354, AD4-13208)
Affinity DataIC50:  1.30E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156418(US9023354, AD4-12905)
Affinity DataIC50:  1.40E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156517(US9023354, AD4-13089)
Affinity DataIC50:  1.60E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47298(BDBM64616 | US9023354, AD4-10960)
Affinity DataIC50:  1.70E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47300(US9023354, AD4-10944)
Affinity DataIC50:  1.70E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156416(US9023354, AD4-12903)
Affinity DataIC50:  1.80E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47307(BDBM50339143 | US9023354, AD4-10942)
Affinity DataIC50:  1.80E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47303(US9023354, AD4-10482)
Affinity DataIC50:  1.80E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156621(US9023354, AD4-13197)
Affinity DataIC50:  1.80E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156635(US9023354, AD4-13210)
Affinity DataIC50:  2.00E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156528(US9023354, AD4-13101)
Affinity DataIC50:  2.00E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156639(US9023354, AD4-13214)
Affinity DataIC50:  2.00E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM156617(US9023354, AD4-13193)
Affinity DataIC50:  2.40E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
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