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Found 4 Enz. Inhib. hit(s) with Target = 'Dopamine beta-hydroxylase' and Ligand = 'BDBM50000439'
TargetDopamine beta-hydroxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50000439(5-Butyl-pyridine-2-carboxylic acid | 5-Butyl-pyrid...)
Affinity DataKi:  149nMpH: 4.5Assay Description:Binding affinity towards Dopamine beta hydroxylase using tyramine substrate at pH 4.5 in the absence of fumarateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50000439(5-Butyl-pyridine-2-carboxylic acid | 5-Butyl-pyrid...)
Affinity DataKi:  149nMAssay Description:Compound was evaluated for the inhibition of Dopamine beta hydroxylase at pH 4.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50000439(5-Butyl-pyridine-2-carboxylic acid | 5-Butyl-pyrid...)
Affinity DataIC50:  50nMAssay Description:Inhibition of bovine adrenal medulla DBH incubated for 25 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50000439(5-Butyl-pyridine-2-carboxylic acid | 5-Butyl-pyrid...)
Affinity DataIC50:  700nMAssay Description:Inhibition of Dopamine beta hydroxylase in spontaneously hypertensive rats; Value ranges from 0.4-1.1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed