BDBM5566 2,6-Diamino-4-cyclohexylmethoxy-5-nitrosopyrimidine::6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine::NU6027::pyrimidine deriv.

SMILES: C1CCC(CC1)COc2c(c(nc(n2)N)N)N=O

InChI Key: InChIKey=DGWXOLHKVGDQLN-UHFFFAOYSA-N

Data: 4 KI  8 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 5566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Spiny starfish)	BDBM5566 (6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
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Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Human)	BDBM5566 (6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Spiny starfish)	BDBM5566 (6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Human)	BDBM5566 (6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	7.5	30
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					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM5566 (6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM5566 (6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase ATR (Human)	BDBM5566 (6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM5566 (6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-A2 [171-432]/Cyclin-dependent kinase 2 (Human)	BDBM5566 (6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30E+3	-8.16	n/a	n/a	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM5566 (6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Spiny starfish)	BDBM5566 (6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		2.50E+3	-7.77	n/a	n/a	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM5566 (6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diam...) Show SMILES Show InChI	GoogleScholar	UniChem		2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair