Search by Patent Identification

---

Patent: (prefix with "US" like US6078908)

Patent	Data	Compounds	HGNC (for human-derived proteins)	Patent Title	Organization	Deposition	Downloads
US10738015	84	42	HGNC:8155 HGNC:8156	1,3-diaza-spiro-[3.4]-octane derivatives	GRÜNENTHAL GMBH	04/04/21	2D 3D TSV
US10738063	246	64		6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide compounds	Pfizer Inc.	04/04/21	2D 3D TSV
US10738007	130	97	HGNC:10251 HGNC:10252	Amide compounds as kinase inhibitors, compositions and methods of treatment	Translation Drug Development, LLC	04/04/21	2D 3D TSV
USRE48150	34	33	HGNC:6857	Apoptosis signal-regulating kinase inhibitors	Gilead Sciences, Inc.	04/04/21	2D 3D TSV
US10736881	141	96	HGNC:4852 HGNC:13315	Benzimidazole derivatives: preparation and pharmaceutical applications	MEI Pharma, Inc.	04/04/21	2D 3D TSV
US10738053	42	4	HGNC:1373 HGNC:10548	Bicyclic compounds as dual ATX/CA inhibitors	Hoffmann-La Roche Inc.	04/04/21	2D 3D TSV
US10738048	152	37	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	04/04/21	2D 3D TSV
US10738074	43	29		Cyclic di-nucleotide compounds as STING agonists	Merck Sharp & Dohme Corp.	04/04/21	2D 3D TSV
US10738052	205	204	HGNC:7029	Imidazotriaines and imidazopyrimidines as kinase inhibitors	INCYTE HOLDINGS CORPORATION; INCYTE CORPORATION	04/04/21	2D 3D TSV
US10738026	17	11	HGNC:10597	Isoquinoline derivatives and use thereof	Purdue Pharma L.P.	04/04/21	2D 3D TSV
US10736890	75	37	HGNC:8156	Methods for treating depressive symptoms	ALKERMES PHARMA IRELAND LIMITED	04/04/21	2D 3D TSV
US10738056	510	501		Pyrazolopyrimidinone compounds and uses thereof	Aduro BioTech Inc.	04/04/21	2D 3D TSV
US10738009	160	158	HGNC:10582	Pyridone amides as modulators of sodium channels	VERTEX PHARMACEUTICALS INCORPORATED	04/04/21	2D 3D TSV
US10736974	64	35	HGNC:3788	Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy	THE JOHNS HOPKINS UNIVERSITY	04/04/21	2D 3D TSV
US10738057	246	118	HGNC:8978 HGNC:8977	Tertiary alcohols as PI3K-γ inhibitors	Incyte Corporation	04/04/21	2D 3D TSV
US10736883	326	315	HGNC:339	Triazole furan compounds as agonists of the APJ receptor	AMGEN INC.	04/04/21	2D 3D TSV
US10723742	270	242	HGNC:29079	Biphenyl compound or salt thereof	Taiho Pharmaceutical Co., Ltd.	03/30/21	2D 3D TSV
US10730902	10	5	HGNC:6561 HGNC:6563	1,1 ′-sulfanediyl-di-beta-D-galactopyranosides as inhibitors of galectins	GALECTO BIOTECH AB	03/28/21	2D 3D TSV
US10730889	403	381	HGNC:30092	Amido spirocyclic amide and sulfonamide derivatives	FORMA TM, LLC; Genentech, Inc.	03/28/21	2D 3D TSV
US10723734	237	230	HGNC:19679	Biaryl kinase inhibitors	Bristol-Myers Squibb Company	03/28/21	2D 3D TSV
US10722495	51	51	HGNC:6863	Cyanoindazole compounds and uses thereof	Incyte Corporation	03/28/21	2D 3D TSV
US10722597	33	4	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:19086 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:4854 HGNC:4853 HGNC:18128	Cyclodextrin-panobinostat adduct	MIDATECH LTD.	03/28/21	2D 3D TSV
US10722489	10	10	HGNC:8923	D-3-phosphoglycerate dehydrogenase allosteric inhibitor and use thereof	Peking University	03/28/21	2D 3D TSV
US10723705	206	204	HGNC:13315	Heterocyclic compounds and uses thereof	Incyte Corporation	03/28/21	2D 3D TSV
US10723709	26	6	HGNC:2536 HGNC:2537 HGNC:2545	Protease inhibitors	MEDIVIR AB	03/28/21	2D 3D TSV
US10723723	220	173	HGNC:6255	Substituted bicycle heterocyclic derivatives useful as ROMK channel inhibitors	Bristol-Myers Squibb Company	03/28/21	2D 3D TSV
US10730882	34	34	HGNC:10436	2-aminoquinazoline derivatives as P70S6 kinase inhibitors	SENTINEL ONCOLOGY LIMITED	03/27/21	2D 3D TSV
US10730880	867	199	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	4,6-substituted-pyrazolo[1,5-a]pyrazines as Janus kinase inhibitors	Array BioPharma Inc.; Celgene Corporation	03/27/21	2D 3D TSV
US10730877	3210	841	HGNC:15633 HGNC:15631 HGNC:15632	4-Azaindole compounds	Bristol-Myers Squibb Company	03/27/21	2D 3D TSV
US10730868	104	95	HGNC:3540	Bicyclic heteroaryl substituted compounds	Bristol-Myers Squibb Company	03/27/21	2D 3D TSV
US10730870	267	140	HGNC:12687	Compounds and methods for the enhanced degradation of targeted proteins	ARVINAS OPERATIONS, INC.; YALE UNIVERSITY	03/27/21	2D 3D TSV
US10730865	49	49		Compounds for modulating aquaporins	APOGLYX AB	03/27/21	2D 3D TSV
US10730860	3	2	HGNC:13575	Diaminopyrimidine benzenesulfone derivatives and uses thereof	Dana-Farber Cancer Institute, Inc.	03/27/21	2D 3D TSV
US10730881	28	28	HGNC:620	Fused pyrimidine derivatives	HOFFMANN-LA ROCHE, INC.	03/27/21	2D 3D TSV
US10730866	84	72	HGNC:10597	Indole derivatives and use thereof	Purdue Pharma L.P.	03/27/21	2D 3D TSV
US10730874	328	296	HGNC:6371	Inhibitors of plasma kallikrein and uses thereof	Shire Human Genetic Therapies, Inc.	03/27/21	2D 3D TSV
US10730875	135	31	HGNC:6190 HGNC:6192 HGNC:12440	Substituted imidazo[1,2-A]pyridin-2-ylamine compounds, and pharmaceutical compositions and methods of use thereof	JN Therapeutics	03/27/21	2D 3D TSV
US10729680	63	63		5-substituted 2-(morpholin-4-yl)-1,7-naphthyridines	BAYER PHARMA AKTIENGESELLSCHAFT	03/21/21	2D 3D TSV
US10730832	130	130		Aliphatic prolinamide derivatives	ORION OPHTHALMOLOGY LLC	03/21/21	2D 3D TSV
US10729684	24	12	HGNC:10597	Alkynyl dihydroquinoline sulfonamide compounds	AMGEN INC.	03/21/21	2D 3D TSV
US10729695	29	29	HGNC:320	Amino, amido and heterocyclic compounds as modulators of RAGE activity and uses thereof	The Research Foundation for the State University of New York; New York University	03/21/21	2D 3D TSV
US10730856	12	12	HGNC:9596	Benzimidazole derivatives as EP4 ligands	BAYER PHARMA AKTIENGESELLSCHAFT	03/21/21	2D 3D TSV
US10730849	95	51		Benzo[b]thiophene compounds as STING agonists	Merck Sharp & Dohme Corp.	03/21/21	2D 3D TSV
US10730863	435	427	HGNC:7967	Bridged bicyclic compounds as farnesoid X receptor modulators	Bristol-Myers Squibb Company	03/21/21	2D 3D TSV
US10729710	17	6	HGNC:3023 HGNC:3020	Catecholamine prodrugs for use in the treatment of Parkinson's disease	H. Lundbeck A/S	03/21/21	2D 3D TSV
US10717746	178	86	HGNC:1780	Chemical compounds	ASTRAZENECA AB	03/21/21	2D 3D TSV
US10730853	36	17	HGNC:5184	Compounds as neuronal histamine receptor-3 antagonists and uses thereof	XW LABORATORIES INC.	03/21/21	2D 3D TSV
US10717737	116	115	HGNC:29079	Cyclopropylamines as LSD1 inhibitors	Incyte Corporation	03/21/21	2D 3D TSV
US10717733	462	116	HGNC:6834 HGNC:550 HGNC:6666	Haloallylamine indole and azaindole derivative inhibitors of lysyl oxidases and uses thereof	Pharmaxis Ltd.	03/21/21	2D 3D TSV
US10717734	176	44	HGNC:6834 HGNC:550 HGNC:6666	Indole and azaindole haloallylamine derivative inhibitors of lysyl oxidases and uses thereof	Pharmaxis Ltd.	03/21/21	2D 3D TSV
US10716791	42	17	HGNC:18367 HGNC:18368	Inhibitors of peptidyl arginine deiminase (PAD) enzymes and uses thereof	University Health Network	03/21/21	2D 3D TSV
US10730826	181	68	HGNC:2531 HGNC:2538 HGNC:2527 HGNC:2536 HGNC:2547 HGNC:2537 HGNC:2545 HGNC:2535	Ketone inhibitors of lysine gingipain	CORTEXYME, INC.	03/21/21	2D 3D TSV
US10717708	62	31	HGNC:3827 HGNC:3826	Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists	Bristol-Myers Squibb Company	03/21/21	2D 3D TSV
US10730850	106	106	HGNC:550	Pyridinylmethyl carbamimidoylcarbamate derivatives and their use as AOC3 inhibitors	Boehringer Ingelheim International GmbH	03/21/21	2D 3D TSV
US10717738	29	29	HGNC:3529	Pyrimidinone and its derivatives inhibiting factor XIa	ONO PHARMACEUTICAL CO., LTD.	03/21/21	2D 3D TSV
US10717742	148	137		Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors	Boehringer Ingelheim International GmbH	03/21/21	2D 3D TSV
US10730833	9	9	HGNC:348	Synthesis of diindolylmethanes and indolo[3,2-b]carbazoles, compounds formed thereby, and pharmaceutical compositions containing them	Wisconsin Alumni Research Foundation	03/21/21	2D 3D TSV
US10730830	51	25	HGNC:3165 HGNC:14299	Tetrahydronaphthalene derivative	ONO PHARMACEUTICAL CO., LTD.	03/21/21	2D 3D TSV
US10717764	402	207		Therapeutically active compounds and their methods of use	Agios Pharmaceuticals, Inc.	03/21/21	2D 3D TSV
US10729691	118	59	HGNC:11005	Treatment of infectious diseases with glucose uptake inhibitors	KADMON CORPORATION, LLC	03/21/21	2D 3D TSV
US10711036	87	87	HGNC:6819	MALT1 inhibitors and uses thereof	Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation	03/15/21	2D 3D TSV
US10711006	65	28	HGNC:4840 HGNC:3697 HGNC:1057 HGNC:1133 HGNC:6193 HGNC:6171 HGNC:2444 HGNC:3765	Selective Bruton's tyrosine kinase inhibitor and use thereof	HANGZHOU HERTZ PHARMACEUTICAL CO., LTD.	03/15/21	2D 3D TSV
US10711007	49	49	HGNC:10894	Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)	Prelude Therapeutics Incorporated	03/15/21	2D 3D TSV
US10711020	881	783		Tricyclic sulfones as RORγ modulators	Bristol-Myers Squibb Company	03/15/21	2D 3D TSV
US10709688	40	16	HGNC:3559 HGNC:3557	Agent for treating synucleinopathy	Tohoku University; National University Corporation Okayama University	03/14/21	2D 3D TSV
US10710980	616	88		Aminopyridine derivatives and their use as selective ALK-2 inhibitors	Novartis AG	03/14/21	2D 3D TSV
US10709712	2614	1072	HGNC:9829	Biaryl amide compounds as kinase inhibitors	NOVARTIS AG	03/14/21	2D 3D TSV
US10709695	2	2		Compounds as rearranged during transfection (RET) inhibitors	GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED	03/14/21	2D 3D TSV
US10709718	28	28	HGNC:2843	Inhibitors of diacylglycerol O-acyltransferase 1 (DGAT-1) and uses thereof	Metabasis Therapeutics, Inc.	03/14/21	2D 3D TSV
US10710994	297	150	HGNC:497	Oxadiazole transient receptor potential channel inhibitors	Genentech, Inc.	03/14/21	2D 3D TSV
US10711004	455	275	HGNC:497	Oxadiazole transient receptor potential channel inhibitors	Genentech, Inc.	03/14/21	2D 3D TSV
US10710986	657	656		PD-1/PD-L1 inhibitors	Gilead Sciences, Inc.	03/14/21	2D 3D TSV
US10710967	299	294	HGNC:9599	Pyrimidine derivative	ASKA PHARMACEUTICAL CO., LTD.	03/14/21	2D 3D TSV
US10710978	234	59	HGNC:11403 HGNC:11408 HGNC:18174 HGNC:11406	STK4 inhibitors for treatment of hematologic malignancies	DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE	03/14/21	2D 3D TSV
US10709719	42	10	HGNC:3167 HGNC:3165	Substituted bicyclic compounds	Bristol-Myers Squibb Company	03/14/21	2D 3D TSV
US10709709	212	203	HGNC:10894	Substituted carbonucleoside derivatives useful as anticancer agents	Pfizer Inc.	03/14/21	2D 3D TSV
US10676499	33	17	HGNC:3287	3′ end caps, 5′ end caps and combinations thereof for therapeutic RNA	NOVARTIS AG	03/11/21	2D 3D TSV
US10676464	43	43		5-hydroxytryptamine receptor 7 activity modulators and their method of use	Temple University Of The Commonwealth System of Higher Education	03/11/21	2D 3D TSV
US10676458	17	11	HGNC:4498	Antidiabetic bicyclic compounds	Merch Sharp & Dohne Corp. Rahway	03/11/21	2D 3D TSV
US10676467	113	58	HGNC:3169 HGNC:3167 HGNC:3165 HGNC:14299 HGNC:3170	Compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof	Washington University	03/11/21	2D 3D TSV
US10676457	130	129	HGNC:29079	Cyclopropylamines as LSD1 inhibitors	Incyte Corporation	03/11/21	2D 3D TSV
US10676465	188	94	HGNC:4324	GLP-1 receptor agonists and uses thereof	Pfizer Inc.	03/11/21	2D 3D TSV
US10676479	360	118	HGNC:17101	Imidazolepyridine compounds and uses thereof	Novartis AG	03/11/21	2D 3D TSV
US10676470	36	34		Inhibitors of lysine gingipain	CORTEXYME, INC.	03/11/21	2D 3D TSV
US10676469	383	182	HGNC:8154 HGNC:8156	Kappa opioid receptor antagonists and products and methods related thereto	BLACKTHORN THERAPEUTICS, INC.; THE SCRIPPS RESEARCH INSTITUTE	03/11/21	2D 3D TSV
US10676485	106	53	HGNC:6943	Macrocyclic MCL-1 inhibitors and methods of use	AbbVie Inc.	03/11/21	2D 3D TSV
US10676460	56	3	HGNC:9077 HGNC:11283 HGNC:11584 HGNC:14552 HGNC:17967 HGNC:12434 HGNC:11724 HGNC:6735 HGNC:2451 HGNC:5465 HGNC:4617 HGNC:2459 HGNC:6112 HGNC:2457 HGNC:3767 HGNC:6190 HGNC:6192 HGNC:6193 HGNC:6171 HGNC:11390 HGNC:12440 HGNC:1079 HGNC:1771 HGNC:1133 HGNC:6860 HGNC:7972 HGNC:6524 HGNC:1775	Quinazolines as potassium ion channel inhibitors	Bristol-Myers Squibb Company	03/11/21	2D 3D TSV
US10676476	30	14	HGNC:3430 HGNC:5253	Small-molecule HSP90 inhibitors	Sloan-Kettering Institute for Cancer Research	03/11/21	2D 3D TSV
US10676446	190	190	HGNC:3357	Bicyclic quinazolinone derivatives	Hoffmann-La Roche Inc.	03/10/21	2D 3D TSV
US10676434	200	178	HGNC:1133	Carbazole derivatives	Bristol-Myers Squibb Company	03/10/21	2D 3D TSV
US10675286	612	109	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Heterocyclic compounds and uses thereof	Infinity Pharmaceuticals, Inc.	03/10/21	2D 3D TSV
US10676433	355	196	HGNC:5992 HGNC:8537	Indole derivatives and their use in neurodegenerative diseases	Merck Patent GmbH	03/10/21	2D 3D TSV
US10676438	16	10	HGNC:6251	KCNQ2-5 channel activator	Ono Pharmaceutical Co., Ltd.	03/10/21	2D 3D TSV
US10676431	270	127	HGNC:3827 HGNC:3826	Phenylpyrrolidinone formyl peptide 2 receptor agonists	Bristol-Myers Squibb Company	03/10/21	2D 3D TSV
US10675268	284	169	HGNC:11330 HGNC:11331 HGNC:11334 HGNC:11332 HGNC:11333	Somatostatin receptor subtype 4 (SSTR4) agonists	Centrexion Therapeutics Corporation	03/10/21	2D 3D TSV
US10675284	37	37	HGNC:6190 HGNC:8977	Treatment of B-cell malignancies by a combination JAK and PI3K inhibitors	Incyte Corporation	03/10/21	2D 3D TSV
US10703751	36	7	HGNC:6192 HGNC:6193	Amino-imidazopyridine derivatives as Janus kinase inhibitors and pharmaceutical use thereof	Leo Pharma A/S	03/08/21	2D 3D TSV
US10703741	26	16	HGNC:18368	Covalent inhibitors of PAD4	Padlock Therapeutics, Inc.	03/08/21	2D 3D TSV
US10702504	21	21	HGNC:11812	Degradation of tripartite motif-containing protein 24 (TRIM24) by conjugation of TRIM24 inhibitors with E3 ligase ligand and methods of use	DANA-FARBER CANCER INSTITUTE, INC.	03/08/21	2D 3D TSV
US10703733	457	445		MCL-1 inhibitors	Gilead Sciences, Inc.	03/08/21	2D 3D TSV
US10702498	27	15	HGNC:8154 HGNC:8156	MU opioid receptor modulators	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; FRIEDRICH-ALEXANDER-UNIVERSITAT ERLANGEN-NÜRNBERG; THE BOARD OF TRUSTEES OFTHE LELAND STANFORD JUNIOR UNIVERSITY; THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	03/08/21	2D 3D TSV
US10703749	843	289	HGNC:8537	P2X7 modulators	Janssen Pharmaceutica NV	03/08/21	2D 3D TSV
US10708263	5	1		Salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders	GALAPAGOS NV	03/08/21	2D 3D TSV
US10703740	14	14	HGNC:13575	Substituted benzimidazoles, their preparation and their use as pharmaceuticals	Neomed Institute	03/08/21	2D 3D TSV
US10703755	351	337	HGNC:15631	Substituted purine derivative	SUMITOMO DAINIPPON PHARMA CO., LTD.	03/08/21	2D 3D TSV
US10696692	374	308	HGNC:30092	Amido-benzyl sulfone and sulfoxide derivates	TBA	03/02/21	2D 3D TSV
US10696672	157	152	HGNC:6161	Amino acid compounds and methods of use	Pliant Therapeutics, Inc.	03/02/21	2D 3D TSV
US10696682	44	44	HGNC:1771	CDK inhibitors	G1 Therapeutics, Inc.	03/02/21	2D 3D TSV
US10696661	70	69	HGNC:11305	Compounds	Exonate Limited	03/02/21	2D 3D TSV
US10696638	48	43	HGNC:10251 HGNC:10252	Compounds for inhibiting AGC kinase and pharmaceutical compositions comprising the same	INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE	03/02/21	2D 3D TSV
US10695334	98	57	HGNC:6371 HGNC:11830	Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors	Boehringer Ingelheim International GmbH	03/02/21	2D 3D TSV
US10696678	154	64	HGNC:1722	Kinase inhibitor, and preparing method and pharmaceutical use thereof	GAN & LEE PHARMACEUTICALS	03/02/21	2D 3D TSV
US10696665	61	23	HGNC:5382	Mutant IDH1 inhibitors	Eli Lilly and Company	03/02/21	2D 3D TSV
US10695337	794	388		Piperidin-4-yl azetidine derivatives as JAK1 inhibitors	Incyte Holdings Corporation; Incyte Corporation	03/02/21	2D 3D TSV
US10695347	84	40	HGNC:427	Pyrimidine derivative and use thereof	HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC.	03/02/21	2D 3D TSV
US10696660	91	36	HGNC:10251 HGNC:10252	Rho kinase inhibitors	Kadmon Corporation, LLC	03/02/21	2D 3D TSV
US10696689	23	23	HGNC:11331	Somatostatin modulators and uses thereof	CRINETICS PHARMACEUTICALS, INC.	03/02/21	2D 3D TSV
US10696655	125	125	HGNC:2348	Therapeutic compounds and uses thereof	GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.	03/02/21	2D 3D TSV
US10689373	308	149	HGNC:4849 HGNC:4848	1,2-substituted cyclopentanes as orexin receptor antagonists	TAKEDA PHARMACEUTICAL COMPANY LIMITED	02/22/21	2D 3D TSV
US10689345	273	269		1-cyano-pyrrolidine compounds as USP30 inhibitors	Mission Therapeutics Limited	02/22/21	2D 3D TSV
US10689401	50	25	HGNC:934 HGNC:933	C5-C6-oxacyclic fused iminothiazine dioxide compounds bearing an ether linker as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp.	02/22/21	2D 3D TSV
US10689705	212	71	HGNC:3690 HGNC:3689 HGNC:3688	FGFR3 fusion gene and pharmaceutical drug targeting same	Chugai Seiyaku Kabushiki Kaisha	02/22/21	2D 3D TSV
US10689346	302	246	HGNC:6371	Human plasma kallikrein inhibitors	BioCryst Pharmaceuticals, Inc.	02/22/21	2D 3D TSV
US10688100	52	13	HGNC:10261	Macrocylic compounds as ROS1 kinase inhibitors	Array BioPharma Inc.	02/22/21	2D 3D TSV
US10688093	708	647	HGNC:4037	Methods, compositions, and uses of novel Fyn kinase inhibitors	TBA	02/22/21	2D 3D TSV
US10689357	43	43	HGNC:736	N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and use thereof	NORTHEASTERN UNIVERSITY	02/22/21	2D 3D TSV
US10689398	91	89	HGNC:8157	OXA-Diazaspiro compounds having activity against pain	ESTEVE PHARMACEUTICALS, S.A.	02/22/21	2D 3D TSV
USRE48059	122	64		Piperazine-substituted benzothiophenes for treatment of mental disorders	Otsuka Pharmaceutical Co., Ltd.	02/22/21	2D 3D TSV
US10689327	30	15	HGNC:4595 HGNC:4594	Prodrug amino acid derivative	TAISHO PHARMACEUTICAL CO., LTD.	02/22/21	2D 3D TSV
US10689339	69	69	HGNC:2545	Pyrrolidine derivatives	Hoffmann-La Roche Inc.	02/22/21	2D 3D TSV
US10689362	508	124	HGNC:8804 HGNC:6342 HGNC:3765	Quinoxaline compounds as type III receptor tyrosine kinase inhibitors	Development Center for Biotechnology	02/22/21	2D 3D TSV
US10689399	23	23	HGNC:9213	Substituted 3,4,5,6,8,10,14,14a-octahydro-2h-2,6-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazocines and methods for treating viral infections	Gilead Sciences, Inc.	02/22/21	2D 3D TSV
US10689369	149	127		Substituted indazole compounds as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp.	02/22/21	2D 3D TSV
US10689376	39	39	HGNC:3356	Substituted-3H-imidazo [4,5-c] pyridine and 1H-pyrrolo[2,3-c]pyridine series of novel ectonucleotide pyrophosphatase/phosphodiesterase-1 (ENPP1) and stimulator for interferon genes (STING) modulators as cancer immunotherapeutics	Stingray Therapeutics, Inc.; The University of Utah	02/22/21	2D 3D TSV
US10689414	404	206		Therapeutically active compounds and their methods of use	Agios Pharmaceuticals, Inc.	02/22/21	2D 3D TSV
US10689367	327	233	HGNC:339	Triazole pyridyl compounds as agonists of the APJ receptor	AMGEN INC.	02/22/21	2D 3D TSV
US10689390	18	18	HGNC:13575	Tricyclic fused derivatives of 1-(cyclo)alkyl pyridin-2-one useful for the treatment of cancer	JUBILANT BIOSYS LIMITED	02/22/21	2D 3D TSV
US10689395	14	14	HGNC:13575	Tricyclic fused pyridin-2-one derivatives and their use as BRD4 inhibitors	JUBILANT BIOSYS LIMITED	02/22/21	2D 3D TSV
US10669240	500	242	HGNC:3091	5-substituted indazole-3-carboxamides and preparation and use thereof	Samumed, LLC	02/21/21	2D 3D TSV
US10669246	153	115	HGNC:8803 HGNC:76 HGNC:6342	Benzothiazol compounds and methods using the same for treating neurodegenerative disorders	1ST Biotherapeutics, Inc.	02/21/21	2D 3D TSV
US10669268	343	306	HGNC:10548	Bicyclic derivatives	Hoffmann-La Roche Inc.	02/21/21	2D 3D TSV
US10669289	209	104	HGNC:9542 HGNC:9545	Boronic acid derivatives	MERCK PATENT GMBH	02/21/21	2D 3D TSV
US10669245	37	37	HGNC:2528	Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides dipeptidyl peptidase 1 inhibitors	ASTRAZENECA AB	02/21/21	2D 3D TSV
US10669285	43	43	HGNC:10548	Condensed [1,4] diazepine compounds as autotaxin (ATX) and lysophosphatidic acid (LPA) production inhibitors	Hoffmann-La Roche Inc.	02/21/21	2D 3D TSV
US10669276	48	48		Fused pyrimidine derivatives	HOFFMANN-LA ROCHE INC.	02/21/21	2D 3D TSV
US10669271	94	30	HGNC:7794 HGNC:9644	Heterocyclic compounds as immunomodulators	Incyte Corporation	02/21/21	2D 3D TSV
US10669279	372	104	HGNC:8780 HGNC:8781 HGNC:8783	Imidazopyridazine compounds	Pfizer Inc.	02/21/21	2D 3D TSV
US10669243	10	10		Isoxazole carboxamides as irreversible SMYD inhibitors	EPIZYME, INC.	02/21/21	2D 3D TSV
US10669296	8	4		LXR agonists and uses thereof	Rgenix, Inc.	02/21/21	2D 3D TSV
US10669265	142	72	HGNC:6307 HGNC:8804 HGNC:9437	Pyridyl benzothiophenes as kinase inhibitors	ALLERGAN, INC.	02/21/21	2D 3D TSV
US10669267	65	39	HGNC:8537	Substituted N-[2-(4-phenoxypiperidin-1-yl)-2-(1,3-thiazol-5-yl)ethyl]benzamide and N-[2-(4-benzyloxypiperidin-1-yl)-2-(1,3-thiazol-5-yl)ethyl]benzamide derivatives P2X7 receptor antagonists	Axxam S.P.A.	02/21/21	2D 3D TSV
US10669273	42	36	HGNC:6059	Use of aza-tryptanthrin derivatives as inhibitors of IDO1 and/or TDO	Peking University	02/21/21	2D 3D TSV
US10683294	67	67	HGNC:1338	5-5 fused rings as C5a inhibitors	ChemoCentryx, Inc.	02/16/21	2D 3D TSV
US10683295	59	29	HGNC:11526 HGNC:6251 HGNC:11527 HGNC:11528	Chiral N-acyl-5,6,7(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-A]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor mediated disorders and chiral synthesis thereof	Ogeda SA	02/16/21	2D 3D TSV
US10683291	3	3	HGNC:3165	Heterocyclic compounds for the treatment of disease	OPPILAN PHARMA LTD.	02/16/21	2D 3D TSV
US10683290	84	80		Tricyclic compounds as anticancer agents	Bristol-Myers Squibb Company	02/16/21	2D 3D TSV
US10683309	84	42	HGNC:12008 HGNC:20692	Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same	MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN; FORSCHUNGSVERBUND BERLIN E.V.	02/16/21	2D 3D TSV
US10668071	105	100		(Aza)pyridopyrazolopyrimidinones and indazolopyrimidinones and their use	BAYER PHARMA AKTIENGESELLSCHAFT	02/15/21	2D 3D TSV
US10667515	17	17		(S)-5-ethynyl-anabasine, derivatives thereof, and related compositions and methods of making and using	Iowa State University Research Foundation, Inc.	02/15/21	2D 3D TSV
US10683279	71	68	HGNC:6857	Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	02/15/21	2D 3D TSV
US10683289	23	23	HGNC:6857	Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	02/15/21	2D 3D TSV
US10682352	117	100	HGNC:5382	Compound having mutant IDH inhibitory activity, preparation method and use thereof	SHANGHAI HAIHE PHARMACEUTICAL CO., LTD.; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES	02/15/21	2D 3D TSV
US10669227	24	9	HGNC:7175 HGNC:7176 HGNC:7166 HGNC:7159	Curcumin analogues as zinc chelators and their uses	THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK	02/15/21	2D 3D TSV
US10669234	193	147	HGNC:12513	Cyanopyrrolidines as dub inhibitors for the treatment of cancer	MISSION THERAPEUTICS LIMITED	02/15/21	2D 3D TSV
US10668167	176	62	HGNC:7978 HGNC:644 HGNC:3467 HGNC:8910	Glucocorticoid receptor agonist and immunoconjugates thereof	AbbVie Inc.	02/15/21	2D 3D TSV
US10683287	96	45	HGNC:934 HGNC:933	Heterocyclic derivatives and their use in the treatment of neurological disorders	Novartis AG	02/15/21	2D 3D TSV
US10669235	336	55	HGNC:8803 HGNC:3763 HGNC:6307 HGNC:8804 HGNC:3690 HGNC:3688	Indole derivatives and their use as protein kinase inhibitors	RESPIVERT LIMITED	02/15/21	2D 3D TSV
US10668051	56	56	HGNC:25896	Modulators of calcium release-activated calcium channel	RHIZEN PHARMACEUTICALS SA	02/15/21	2D 3D TSV
US10668033	4	4	HGNC:9602	Modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto	ARENA PHARMACEUTICALS, INC.	02/15/21	2D 3D TSV
US10668067	135	135	HGNC:10597	Pyridine sulfonamides	AMGEN INC.	02/15/21	2D 3D TSV
US10668094	92	21		Selective inhibitors of Alpha2-containing isoforms of Na,K-ATPase and use thereof for reduction of intraocular pressure	Yeda Research and Development Co. Ltd.	02/15/21	2D 3D TSV
US10669239	74	68	HGNC:8031	Tetrahydronaphthyl urea derivative	MOCHIDA PHARMACEUTICAL CO., LTD.	02/15/21	2D 3D TSV
US10660877	2542	841	HGNC:15633 HGNC:15631 HGNC:15632	Pyridyl substituted indole compounds	Bristol-Myers Squibb Company	02/08/21	2D 3D TSV
US10662159	204	60	HGNC:3553 HGNC:17038 HGNC:21398	ABHD6 and dual ABHD6/MGL inhibitors and their uses	MAKSCIENTIFIC, LLC	02/07/21	2D 3D TSV
US10660876	90	89	HGNC:2771	Amino compounds for treatment of medical disorders	Achillion Pharmaceuticals, Inc.	02/07/21	2D 3D TSV
US10662184	150	83	HGNC:10593 HGNC:10585 HGNC:10596	Benzenesulfonamide compounds and their use as therapeutic agents	Xenon Pharmaceuticals Inc.	02/07/21	2D 3D TSV
US10660898	27	27	HGNC:8972	Benzimidazole derivatives as PI3 kinase inhibitors	GLAXOSMITHKLINE LLC	02/07/21	2D 3D TSV
US10662187	134	124	HGNC:6735 HGNC:1057 HGNC:1133 HGNC:3236 HGNC:6524	Bruton's tyrosine kinase inhibitors	Zibo Biopolar Changsheng Pharmaceutical Co. Ltd.; Shanghai Institute of Materia Medica, Chinese Academy of Sciences	02/07/21	2D 3D TSV
US10662156	94	90	HGNC:6819	Guanidine derivative and medical use thereof	Toray Industries, Inc.	02/07/21	2D 3D TSV
US10662189	84	78	HGNC:8781	PDE4 inhibitor	SHIJIAZHUANG SAGACITY NEW DRUG DEVELOPMENT CO., LTD.	02/07/21	2D 3D TSV
US10662186	650	137	HGNC:1780 HGNC:1771 HGNC:1778 HGNC:1722 HGNC:1777 HGNC:1774 HGNC:1773	Substituted pyrimidines as cyclin-dependent kinase inhibitors	SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.	02/07/21	2D 3D TSV
US10654833	96	90	HGNC:6857	ASK1 isoindolin-1-one inhibitors and methods of use thereof	Hepatikos Therapeutics, LLC	02/01/21	2D 3D TSV
US10654857	68	7	HGNC:10555	Bicyclic compounds as autotaxin (ATX) and lysophosphatidic acid (LPA) production inhibitors	Hoffman-La Roche Inc.	02/01/21	2D 3D TSV
US10654835	207	69		Compounds and methods for inhibiting JAK	Dizal (Jiangsu) Pharmaceutical Co., Ltd.	02/01/21	2D 3D TSV
US10654856	20	17	HGNC:15631 HGNC:15632	Method for preparing pyrrolo[3,2-D]pyrimidine compound, and intermediates thereof	CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.	02/01/21	2D 3D TSV
US10654855	73	73	HGNC:391	Protein kinase B inhibitors	AstraZeneca AB	02/01/21	2D 3D TSV
US10654836	40	10	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Pyrimidine derivative, method for preparing same and use thereof in medicine	Zhejiang Hisun Pharmaceutical Co., Ltd.	02/01/21	2D 3D TSV
US10654866	44	21	HGNC:3467	Selective estrogen receptor degraders	Eli Lilly and Company	02/01/21	2D 3D TSV
US10654853	147	145		Spiro-condensed pyrrolidine derivatives as deubiquitylating enzymes (DUB) inhibitors	MISSION THERAPEUTICS LIMITED	02/01/21	2D 3D TSV
US10654860	35	31	HGNC:10252	Tricyclic rho kinase inhibitors	Bristol-Myers Squibb Company	02/01/21	2D 3D TSV
US10653688	302	143	HGNC:4617 HGNC:3091	6-(6-membered heteroaryl and aryl)isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	01/31/21	2D 3D TSV
US10654831	85	14	HGNC:1780 HGNC:1771 HGNC:1774 HGNC:1773 HGNC:1775	Antiproliferative pyrimidine-based compounds	G1 Therapeutics, Inc.	01/31/21	2D 3D TSV
US10654814	240	127	HGNC:4852 HGNC:14064 HGNC:13315 HGNC:4854 HGNC:4853	Bicyclic hydroxamic acids useful as inhibitors of mammalian histone deacetylase activity	KANCERA AB	01/31/21	2D 3D TSV
US10653701	103	52	HGNC:6307 HGNC:1133 HGNC:6193 HGNC:3689 HGNC:3236 HGNC:3688	Substituted quinazolines for inhibiting kinase activity	NEUPHARMA, INC.	01/31/21	2D 3D TSV
US10647665	39	33		Biaryl urea derivative or salt thereof and preparation process and use for the same	Fudan University	01/25/21	2D 3D TSV
US10647719	107	5	HGNC:10555 HGNC:1373	Bicyclic compounds as dual ATX/CA inhibitors	Hoffmann-La Roche Inc.	01/25/21	2D 3D TSV
US10647706	40	14	HGNC:6026 HGNC:6027	Chemokine CXCR1 and CXCR2 receptor antagonist compounds, and use thereof in the treatment of chemokine-mediated pathologies	GALDERMA RESEARCH & DEVELOPMENT	01/25/21	2D 3D TSV
US10647694	45	40	HGNC:427	Diphenylaminopyrimidine and triazine compound, and pharmaceutical composition and use thereof	ARROMAX PHARMATECH CO., LTD.	01/25/21	2D 3D TSV
US10647700	14	14		EZH2 inhibitor and use thereof	TARAPEUTICS SCIENCE INC.	01/25/21	2D 3D TSV
US10646575	3	3	HGNC:2717	Heterocyclic degronimers for target protein degradation	C4 Therapeutics, Inc.	01/25/21	2D 3D TSV
US10646492	366	342	HGNC:8977	Heterocyclylamines as PI3K inhibitors	Incyte Corporation; Incyte Holdings Corporation	01/25/21	2D 3D TSV
US10647720	614	333	HGNC:6192 HGNC:11491	Pyrimido-pyridazinone compounds and methods of use thereof	Asan BioSciences, LLC	01/25/21	2D 3D TSV
US10647727	66	47	HGNC:8777	Substituted pyrazolo/imidazolo bicyclic compounds as PDE2 inhibitors	Merck Sharp & Dohme Corp.	01/25/21	2D 3D TSV
US10647686	82	50	HGNC:11396 HGNC:11395	Substituted pyrimidines for preventing or treating cancer and inflammatory diseases	KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY	01/25/21	2D 3D TSV
US10647713	620	601		TYK2 inhibitors and uses thereof	Nimbus Lakshmi, Inc.	01/25/21	2D 3D TSV
US10647708	46	46	HGNC:10894	Tetrahydroisoquinoline derived PRMT5-inhibitors	CTXT PTY. LTD	01/25/21	2D 3D TSV
US10639286	194	172		Alkoxy compounds for disease treatment	ACUCELA INC.	01/18/21	2D 3D TSV
US10640498	69	68		Compounds	MISSION THERAPEUTICS LIMITED	01/18/21	2D 3D TSV
US10640533	114	19	HGNC:2524 HGNC:24059 HGNC:9537	Epoxyketone compounds for enzyme inhibition	CENTRAX INTERNATIONAL, INC.	01/18/21	2D 3D TSV
US10640486	86	85	HGNC:1133	Heteroarylcarboxamide derivatives as plasma kallikrein inhibitors	Boehringer Ingelheim International GmbH	01/18/21	2D 3D TSV
US10640495	646	615	HGNC:8031	Heterocycle derivatives having TrkA inhibitory activity	Shionogi & Co., Ltd.	01/18/21	2D 3D TSV
US10640503	158	158	HGNC:29079	Imidazopyridines and imidazopyrazines as LSD1 inhibitors	Incyte Corporation	01/18/21	2D 3D TSV
US10639284	329	312	HGNC:17635	Immunomodulator compounds	ChemoCentryx, Inc.	01/18/21	2D 3D TSV
US10640491	20	20	HGNC:1133	Inhibitors of bruton's tyrosine kinase	HOFFMANN-LA ROCHE INC.	01/18/21	2D 3D TSV
US10640534	402	205		Therapeutically active compositions and their methods of use	Agios Pharmaceuticals, Inc.	01/18/21	2D 3D TSV
US10633384	113	113	HGNC:10555	Diazaspirocycloalkane and azaspirocycloalkane	Hoffmann-La Roche Inc.	01/12/21	2D 3D TSV
US10632126	676	168	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	01/10/21	2D 3D TSV
US10633379	264	130		Bromodomain inhibitors	AbbVie Inc.	01/10/21	2D 3D TSV
US10633389	1029	1023	HGNC:23393	CARM1 inhibitors and uses thereof	Epizyme, Inc.	01/10/21	2D 3D TSV
US10632122	116	115		Compositions and methods for treating toxoplasmosis, cryptosporidiosis and other apicomplexan protozoan related diseases	University of Washington	01/10/21	2D 3D TSV
US10633345	302	248	HGNC:6371	Human plasma kallikrein inhibitors	BioCryst Pharmaceuticals, Inc.	01/10/21	2D 3D TSV
US10632171	152	130	HGNC:6932 HGNC:4479	Melanocortin receptor-specific peptides	Palatin Technologies, Inc.	01/10/21	2D 3D TSV
US10633348	39	16	HGNC:4840 HGNC:1133 HGNC:4195 HGNC:7972	Methods to treat lymphoplasmacytic lymphoma	Dana-Farber Cancer Institute, Inc.	01/10/21	2D 3D TSV
US10633375	111	107	HGNC:3529	Oxopicolinamide derivative, preparation method therefor and pharmaceutical use thereof	Jinagsu Hengrui Medicine Co., Ltd; Shanghai Hengrui Pharmaceutical Co., Ltd.	01/10/21	2D 3D TSV
US10633388	19	14	HGNC:4421	Pyrazolopyrimidone derivatives and methods of use thereof	Shanghai Hengrui Pharmaceutical Co., ltd.; Jiangsu Hangrui Medicine Co., Ltd.	01/10/21	2D 3D TSV
US10633373	123	72	HGNC:6307 HGNC:8804 HGNC:9437	Pyridyl benzothiophenes as kinase inhibitors	Allergan, Inc.	01/10/21	2D 3D TSV
US10604514	334	150	HGNC:4617 HGNC:3091	6-(5-membered heteroaryl)isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	12/21/20	2D 3D TSV
US10604534	38	19	HGNC:934 HGNC:933	C5-C6-oxacyclic fused iminothiadiazine dioxide compounds bearing an ether linker as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp.	12/21/20	2D 3D TSV
US10604535	251	240		Compounds, compositions and methods	Denali Therapeutics Inc.	12/21/20	2D 3D TSV
US10604531	11	11	HGNC:3527	Enhancer of zeste homolog 2 inhibitors	GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED	12/21/20	2D 3D TSV
US10604536	59	54	HGNC:8772	Substituted cyclopropanes as PDE-10 inhibitors	Sunovion Pharamaceuticals Inc.	12/21/20	2D 3D TSV
US10604508	11	11	HGNC:1133	2,3-dihydro-isoindole-1-one derivative as BTK kinase suppressant, and pharmaceutical composition including same	CrystalGenomics, Inc.	12/20/20	2D 3D TSV
US10603310	14	12	HGNC:933	2-amino-6-(difluoromethyl)-5,5-difluoro-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors	H. Lundbeck A/S	12/20/20	2D 3D TSV
US10618929	21	20	HGNC:15631	3-substituted 5-amino-6H-thiazolo[4,5-D]pyrimidine-2, 7-dione compounds for the treatment and prophylaxis of virus infection	Hoffmann-La Roche Inc.	12/20/20	2D 3D TSV
US10618900	52	27	HGNC:4597 HGNC:4593	5-aromatic alkynyl substituted benzamide compound and preparation method, pharmaceutical composition, and use thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	12/20/20	2D 3D TSV
US10618914	79	43	HGNC:11364 HGNC:11362	6-aryl-7-substituted-3-(1H-pyrazol-5-yl)-7H-[1,2,4]triazolo[3,4-B][1,3,4]thiadiazines as inhibitors of the STAT3 pathway with anti-proliferative activity	University of Pittsburgh—Of the Commonwealth System of Higher Education	12/20/20	2D 3D TSV
US10603330	131	65	HGNC:663 HGNC:664	Arginase inhibitors as therapeutics	Mars, Incorporated	12/20/20	2D 3D TSV
US10618886	36	17	HGNC:5184	Compounds as neuronal histamine receptor-3 antagonists and uses thereof	XW LABORATORIES INC.	12/20/20	2D 3D TSV
US10604489	172	171	HGNC:8156	Compounds for the treatment of pain	Alkermes, Inc.	12/20/20	2D 3D TSV
US10603320	9	3	HGNC:10258	Compounds useful for inhibiting ROR-gamma-t	Eli Lilly and Company	12/20/20	2D 3D TSV
US10618884	16	1	HGNC:427	Deuterated diaminopyrimidine compounds and pharmaceutical compositions comprising such compounds	Suzhou Zelgen Biopharmaceuticals Co., Ltd.	12/20/20	2D 3D TSV
US10618912	55	18	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:8031 HGNC:8032 HGNC:8033 HGNC:427 HGNC:10261 HGNC:11397	Diaryl macrocycles as modulators of protein kinases	Turning Point Therapeutics, Inc.	12/20/20	2D 3D TSV
US10618903	287	262	HGNC:17967	Heteroaryl substituted aminopyridine compounds	Bristol-Myers Squibb Company	12/20/20	2D 3D TSV
US10618916	68	68		Heterocyclic compounds as immunomodulators	Incyte Corporation	12/20/20	2D 3D TSV
US10604504	262	222	HGNC:1133	Indole carboxamide compounds	Bristol-Myers Squibb Company	12/20/20	2D 3D TSV
US10618913	114	37	HGNC:8775 HGNC:8774 HGNC:8776	Macrocycles as PDE1 inhibitors	H. Lundbeck A/S	12/20/20	2D 3D TSV
US10618897	168	161	HGNC:2730	Spiroindolinones as DDR1 inhibitors	Hoffmann-La Roche Inc.	12/20/20	2D 3D TSV
US10604502	112	111	HGNC:29079	Substituted 5-cyanoindole compounds and uses thereof	Novartis AG	12/20/20	2D 3D TSV
US10618902	256	249	HGNC:3691	Substituted pyrido[2,3-d]pyrimidines as inhibitors of protein kinases	Celgene CAR LLC; Sanofi	12/20/20	2D 3D TSV
US10618910	58	29		Tricyclic heterocycles as BET protein inhibitors	Incyte Corporation	12/20/20	2D 3D TSV
US10597383	35	35		Bicyclic proline compounds	Genentech, Inc.	12/14/20	2D 3D TSV
US10597387	19	8	HGNC:4840 HGNC:1133 HGNC:7972	Methods to treat lymphoplasmacytic lymphoma	Dana-Farber Cancer Institute, Inc.	12/14/20	2D 3D TSV
US10597399	40	39	HGNC:270	Substituted triazolopiperazine PARP inhibitor, preparation method therefor and use thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	12/14/20	2D 3D TSV
US10597382	16	15	HGNC:6857	Tetrazole containing apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	12/14/20	2D 3D TSV
US10596172	747	259	HGNC:1079 HGNC:1133 HGNC:6193 HGNC:6171 HGNC:3236	2,4-disubstituted pyrimidines useful as kinase inhibitors	Celgene CAR LLC	12/13/20	2D 3D TSV
US10597366	413	325	HGNC:12680 HGNC:3374	Aryl ethers and uses thereof	Peloton Therapeutics, Inc.	12/13/20	2D 3D TSV
US10596184	158	76	HGNC:8978 HGNC:8977	Aza-heteroaryl compounds as PI3K-gamma inhibitors	Incyte Corporation	12/13/20	2D 3D TSV
US10617673	8	8		Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes	Jenrin Discovery, LLC	12/13/20	2D 3D TSV
US10617706	43	42	HGNC:17768	Compounds for cancer chemotherapeutic sensitization	REGENTS OF THE UNIVERSITY OF MINNESOTA; THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES	12/13/20	2D 3D TSV
US10597367	724	191		Metabotropic glutamate receptor negative allosteric modulators (NAMs) and uses thereof	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	12/13/20	2D 3D TSV
US10610125	24	5	HGNC:5382 HGNC:6541 HGNC:6535	Methods and compositions for cell-proliferation-related disorders	Agios Pharmaceuticals, Inc.	12/13/20	2D 3D TSV
US10617692	4	4	HGNC:6192	Pyrrolopyrimidine comprising cyclopentyl substituent	CENTAURUS BIOPHARMA CO.; CHIA TAI TIANQING PHARMACEUTICAL GROUP CO.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.	12/13/20	2D 3D TSV
US10597377	268	258	HGNC:11331	Somatostatin modulators and uses thereof	CRINETICS PHARMACEUTICALS, INC.	12/13/20	2D 3D TSV
US10617676	596	594	HGNC:4586	Substituted 1H-imidazo[4,5-b]pyridin-2(3H)-ones and their use as GluN2B receptor modulators	JANSSEN PHARMACEUTICA NV	12/13/20	2D 3D TSV
US10617680	423	397	HGNC:2348	Therapeutic compounds	CELGENE QUANTICEL RESEARCH, INC.	12/13/20	2D 3D TSV
US10617654	78	26	HGNC:286	Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas	The USA, as represented by the Secretary, Department of Health and Human Services; SRI International	12/13/20	2D 3D TSV
US10590106	12	6	HGNC:6307	Certain chemical entities, compositions, and methods	NeuPharma, Inc.	12/08/20	2D 3D TSV
US10590105	56	56		1,3-dihydroxy-phenyl derivatives useful as immunomodulators	Bristol-Meyers Squibb Company	12/07/20	2D 3D TSV
US10611727	18	18		1-[1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives	UNIVERSITAT DE BARCELONA; FUNACIÓ INSTITUT DE RECERCA BIOMÉDICA; IPROTEOS S.L.	12/07/20	2D 3D TSV
US10611730	212	212	HGNC:13628	Benzimidazolone and benzothiazolone compounds and their use as AMPA receptor modulators	Janssen Pharmaceutica NV	12/07/20	2D 3D TSV
US10610539	14	14		Cardiac glycoside analogs and their use in methods for inhibition of viral infection	The John Hopkins University	12/07/20	2D 3D TSV
US10590130	121	63	HGNC:6251	Chemical compounds	AstraZeneca AB	12/07/20	2D 3D TSV
US10590114	215	161	HGNC:18618	Compounds, compositions, and methods	Denali Therapautics Inc.	12/07/20	2D 3D TSV
US10611770	26	26	HGNC:427	Condensed-ring pyrimidylamino derivative, preparation method therefor, and intermediate, pharmaceutical composition and applications thereof	GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD.	12/07/20	2D 3D TSV
US10590075	29	29		Cyanopyrrolidine derivatives as inhibitors for DUBs	MISSION THERAPEUTICS LIMITED	12/07/20	2D 3D TSV
US10611751	15	15	HGNC:3020	Dopamine D1 receptor positive allosteric modulators	Eli Lilly and Company	12/07/20	2D 3D TSV
US10590109	85	24		Heterocyclic compounds used as FGFR inhibitors	Nanjing InnoCare Pharma Tech Co., Ltd.	12/07/20	2D 3D TSV
US10611763	116	114	HGNC:17071	Histone demethylase inhibitors	Celgene Quanticel Research, Inc.	12/07/20	2D 3D TSV
US10611777	156	69	HGNC:8979 HGNC:8978 HGNC:8980 HGNC:8977	Imidazopyridazine compounds and their use	HUTCHISON MEDIPHARMA LIMITED	12/07/20	2D 3D TSV
US10611728	246	97	HGNC:6251 HGNC:8157	Isoindoline compositions and methods for treating neurodegenerative disease	COGNITION THERAPEUTICS, INC.	12/07/20	2D 3D TSV
US10590139	60	60	HGNC:8031	Method of treatment using substituted imidazo[1,2b]pyridazine compounds	Array BioPharma Inc.	12/07/20	2D 3D TSV
US10611766	279	95	HGNC:1133 HGNC:3236	Pyrazolopyrimidine derivatives as BTK inhibitors for the treatment of cancer	Loxo Oncology Inc.	12/07/20	2D 3D TSV
US10590132	289	159	HGNC:6251	Selective estrogen receptor down-regulators	AstraZeneca AB	12/07/20	2D 3D TSV
US10590077	7	7	HGNC:18083	TRPV4 antagonists	GlaxoSmithKline Intellectual Property Development Limited	12/07/20	2D 3D TSV
US10590140	785	438	HGNC:11048	Tetrahydropyrimidodiazepine and dihydropyridodiazepine compounds for treating pain and pain related conditions	ESTEVE PHARMACEUTICALS, S.A.	12/07/20	2D 3D TSV
US10570125	40	16	HGNC:2160 HGNC:2159	(Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles	Centrexion Therapeutics Corporation	11/30/20	2D 3D TSV
US10570116	153	53	HGNC:270 HGNC:11941 HGNC:15677	1,4-dicarbonyl-piperidyl derivatives	Merck Patent GmbH	11/30/20	2D 3D TSV
US10568884	22	22		Compounds and compositions as protein kinase inhibitors	Array BioPharma Inc.	11/30/20	2D 3D TSV
US10570167	249	149	HGNC:8021	Ectonucleotidase inhibitors and methods of use thereof	Calithera Biosciences, Inc.	11/30/20	2D 3D TSV
US10570155	21	8	HGNC:9829 HGNC:1097	Imidazooxazole derivative having antitumor effect, and pharmaceutical composition including same	KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY	11/30/20	2D 3D TSV
US10570118	43	40	HGNC:1133	Isoquinolones as BTK inhibitors	Boehringer Ingelheim International GmbH	11/30/20	2D 3D TSV
US10570123	100	51	HGNC:10251 HGNC:10252	Pharmacokinetically improved compounds	SURFACE LOGIX, LLC	11/30/20	2D 3D TSV
US10570140	42	42	HGNC:29652	Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)	Prelude Therapeutics Incorporated	11/30/20	2D 3D TSV
US10570077	7	7	HGNC:3467	Substituted (4'-hydroxyphenyl)cyclohexane compounds and uses thereof as selective agonists of the estrogen receptor beta isoform	Marquette University; Concordia University Inc.	11/30/20	2D 3D TSV
US10570121	412	114	HGNC:3527	Substituted dihydroisoquinolinone compounds	Pfizer Inc.	11/30/20	2D 3D TSV
US10570156	42	42	HGNC:8772	Substituted imidazo[1,2-a]pyridines as PDE-10 inhibitors	SUNOVION PHARMACEUTICALS INC.	11/30/20	2D 3D TSV
US10570141	14	7	HGNC:1777 HGNC:1773	Substituted pyrrolopyrimidine CDK inhibitor, pharmaceutical composition containing same and use thereof	CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; CENTAURUS BIOPHARMA CO., LTD.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.	11/30/20	2D 3D TSV
US10568876	141	138	HGNC:16940	Tetrahydroisoquinoline derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2	Merck Sharp & Dohme Corp.	11/30/20	2D 3D TSV
US10568888	26	13	HGNC:8781 HGNC:8783	Tricyclic compounds as modulators of TNF-alpha synthesis and as PDE4 inhibitors	vTv Therapeutics LLC	11/30/20	2D 3D TSV
US10584127	26	11	HGNC:4586 HGNC:6251 HGNC:2625	3,3-difluoropiperidine carbamate heterocyclic compounds as NR2B NMDA receptor antagonists	Rugen Holdings (Cayman) Limited	11/29/20	2D 3D TSV
US10584111	25	22	HGNC:4597	4-(3-cyanophenyl)-6-pyridinylpyrimidine mGlu5 modulators	Heptares Therapeutics Limited	11/29/20	2D 3D TSV
US10577368	81	61	HGNC:268 HGNC:262 HGNC:263	A3 adenosine receptor agonists	The United States of America, as represented by the Secretary, Department of Health and Human Services; Saint Louis University	11/29/20	2D 3D TSV
US10584120	58	58	HGNC:9753	Benzimidazole compounds and use thereof for treating Alzheimer's Disease or Huntington's Disease	National Health Research Institutes; Academia Sinica	11/29/20	2D 3D TSV
US10577374	360	356	HGNC:1133	Bruton's tyrosine kinase inhibitors	Sunesis Pharmaceuticals, Inc.; Biogen MA Inc.	11/29/20	2D 3D TSV
US10584104	18	18	HGNC:17989	Carboxylic acid URAT1 inhibitor containing diarylmethane structure, preparation method and use thereof	TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH CO., LTD.	11/29/20	2D 3D TSV
US10584121	10	10		Heteroaryl substituted benzoic acids as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp.	11/29/20	2D 3D TSV
US10584116	51	51	HGNC:497	Heterocyclic sulfonamide derivative and medicine containing same	EA Pharma Co., Ltd.	11/29/20	2D 3D TSV
US10568874	8	8	HGNC:17635	Indane-amines as PD-L1 antagonists	ChemoCentryx, Inc.	11/29/20	2D 3D TSV
US10583140	12	12		Ingenol analogs, pharmaceutical compositions and methods of use thereof	GlaxoSmithKline Intellectual Property Development Limited	11/29/20	2D 3D TSV
US10584114	82	41	HGNC:9967	Inhibitors of RET	BLUEPRINT MEDICINES CORPORATION	11/29/20	2D 3D TSV
US10577383	78	37	HGNC:7218	Macrocyclic inhibitors of myeloperoxidase	Bristol-Myers Squibb Company	11/29/20	2D 3D TSV
US10584098	12	12		Quinolone-3-diarylethers	Oregon Health & Science University	11/29/20	2D 3D TSV
US10584132	20	12	HGNC:10852 HGNC:10850	SHMT inhibitors	The Trustees of Princeton University	11/29/20	2D 3D TSV
US10584103	224	211	HGNC:8039	Small molecule agonists of neurotensin receptor 1	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	11/29/20	2D 3D TSV
US10584135	348	174	HGNC:3023 HGNC:3024	Substituted 3,6-diazabicyclo[3.2.0]heptanes	INDIVIOR UK LIMITED	11/29/20	2D 3D TSV
US10577373	1366	1143		TYK2 inhibitors and uses thereof	Nimbus Lakshimi, Inc.	11/29/20	2D 3D TSV
US10583137	116	56	HGNC:1165 HGNC:28923	Triazole DAGLα inhibitors	THE SCRIPPS RESEARCH INSTITUTE; LEIDEN UNIVERSITY	11/29/20	2D 3D TSV
US10584134	79	69	HGNC:17961	Use of physiological cooling active ingredients, and agents containing such active ingredients	SYMRISE AG; BASF SE	11/29/20	2D 3D TSV
US10561662	73	73	HGNC:19995	4-oxo-3,4-dihydro-1,2,3-benzotriazine modulators of GPR139	Takeda Pharmaceutical Company Limited	11/22/20	2D 3D TSV
US10562893	49	22	HGNC:6171 HGNC:11719 HGNC:12434	Benzimidazoles derivatives as Tec kinases family inhibitors	GB005, INC.	11/22/20	2D 3D TSV
US10562890	16	15	HGNC:10471	Cancer therapeutics	UNIVERSITY OF VIRGINIA PATENT FOUNDATION	11/22/20	2D 3D TSV
US10562861	41	14	HGNC:6251 HGNC:15631 HGNC:15632	Carboxylic acid compounds	Sumitomo Dainippon Pharma Co., Ltd.	11/22/20	2D 3D TSV
US10562853	189	63	HGNC:3023 HGNC:5286 HGNC:277	Compounds for treating disorders sensitive to serotoninergic regulation controlled by the 5-HT1A receptors	NEUROLIXIS; UNIVERSITE JAGELLONE	11/22/20	2D 3D TSV
US10562888	6	1	HGNC:3682 HGNC:3690 HGNC:3689 HGNC:3688	Crystalline FGFR4 inhibitor compound and uses thereof	Eisai R&D Management Co., LTD.	11/22/20	2D 3D TSV
US10562878	1149	222	HGNC:11050 HGNC:11049	Cycloalkylamines as monoamine reuptake inhibitors	SUNOVION PHARAMCEUTICALS INC.	11/22/20	2D 3D TSV
US10562844	14	14		HYPDH inhibitors and methods of use for the treatment of kidney stones	Wake Forest University Health Sciences; UAB Research Foundation	11/22/20	2D 3D TSV
US10562850	103	100	HGNC:6371	Human plasma kallikrein inhibitors	BioCryst Pharmaceuticals, Inc.	11/22/20	2D 3D TSV
US10562902	175	164	HGNC:17967	IRAK4 inhibitor and use thereof	Beijing Hanmi Pharmaceutical Co., Ltd.	11/22/20	2D 3D TSV
US10562900	131	57	HGNC:6307 HGNC:3690 HGNC:3689 HGNC:3688	Indazole compounds as FGFR kinase inhibitor, preparation and use thereof	Shanghai Haihe Pharmaceutical Co., Ltd.; Shanghai Institute of Materia Medica, Chinese Academy of Sciences	11/22/20	2D 3D TSV
US10562910	9	9	HGNC:7967	Nitrogen-containing tricyclic compounds and uses thereof in medicine	NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED	11/22/20	2D 3D TSV
US10561656	9	5	HGNC:8775 HGNC:8774	Organic compounds	INTRA-CELLULAR THERAPIES, INC.	11/22/20	2D 3D TSV
US10562882	43	41		Piperidine derivatives for use in the treatment or prevention of psychiatric and neurological conditions	Takeda Pharmaceutical Company Limited	11/22/20	2D 3D TSV
US10562854	32	16	HGNC:1232 HGNC:12680	Prolyl hydroxylase inhibitors	AERPIO THERAPEUTICS, INC.	11/22/20	2D 3D TSV
US10561657	26	23	HGNC:6192	Pyrrolopyrimidine compound	Centaurus Biophrama Co., Ltd.; Chia Tai Tianqing Pharmaceutical Group Co., Ltd.; Lianyungang Runzhong Pharmaceutical Co., Ltd.	11/22/20	2D 3D TSV
US10562891	435	427		Quinazolinones as PARP14 inhibitors	Ribon Therapeutics Inc.	11/22/20	2D 3D TSV
US10561655	27	27	HGNC:9644	SHP2 inhibitors and uses thereof	SYNBLia Therapeutics, Inc.	11/22/20	2D 3D TSV
US10562916	209	206	HGNC:8772	Substituted quinoxalines as PDE-10 inhibitors	Sunovion Pharmaceuticals, Inc.	11/22/20	2D 3D TSV
US10562887	182	177	HGNC:10252	Triazolones and tetrazolones as inhibitors of ROCK	Bristol-Myers Squibb Company	11/22/20	2D 3D TSV
US10577367	528	508	HGNC:17967	IRAK4 inhibiting agents	BIOGEN MA INC.	11/21/20	2D 3D TSV
US10550117	11	11	HGNC:6853	2-azabicyclo[3.1.0]hexan-3-one derivatives and methods of use	Genentech, Inc.	11/20/20	2D 3D TSV
US10577353	28	27		5-(n-[6,5]-fused bicyclic aryl tetrahydroisoquinolin-6-yl) pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication	ViiV HEALTHCARE UK (NO.5) LIMITED	11/20/20	2D 3D TSV
US10577360	308	153	HGNC:8156 HGNC:1399	Arylamide derivatives having multimodal activity against pain	ESTEVE PHARMACEUTICALS, S.A.	11/20/20	2D 3D TSV
US10577354	6	6		Bis-pyridazine compounds and their use in treating cancer	Cancer Research Technology Limited	11/20/20	2D 3D TSV
US10577352	67	37	HGNC:3236	Cot modulators and methods of use thereof	Gilead Sciences, Inc.	11/20/20	2D 3D TSV
US10577361	69	33	HGNC:3023 HGNC:3024	Dopamine D3 receptor antagonists having a morpholine moiety	INDIVIOR UK LIMITED	11/20/20	2D 3D TSV
US10550140	43	43	HGNC:2771	Ether compounds for treatment of complement mediated disorders	Achillion Pharmaceuticals, Inc.	11/20/20	2D 3D TSV
US10576087	116	58		Fused tricyclic compounds as Raf kinase inhibitors	BEIGENE, LTD.	11/20/20	2D 3D TSV
US10550102	161	159		Indane and indoline derivatives and the use thereof as soluble guanylate cyclase activators	NOVARTIS AG	11/20/20	2D 3D TSV
US10550127	20	20	HGNC:4498	Indanylaminoazadihydrobenzofuranylacetic acids, pharmaceutical compositions for the treatment of diabetes	Boehringer Ingelheim International GmbH	11/20/20	2D 3D TSV
US10550118	56	24	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	JAK inhibitors containing a 4-membered heterocyclic amide	Theravance Biopharma R&D IP, LLC	11/20/20	2D 3D TSV
US10550114	65	21	HGNC:391	Kinase inhibitors and their use in cancer therapy	TECHNISCHE UNIVERSITÄT DORTMUND	11/20/20	2D 3D TSV
US10577330	196	28	HGNC:6160 HGNC:6161 HGNC:6163 HGNC:6141 HGNC:6156	Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists	Saint Louis University	11/20/20	2D 3D TSV
US10577336	169	87	HGNC:11330 HGNC:11331 HGNC:11334 HGNC:11332 HGNC:11333	Morpholine and 1,4-oxazepane amides as somatostatin receptor subtype 4 (SSTR4) agonists	Boehringer Ingelheim International GmbH	11/20/20	2D 3D TSV
US10544150	223	221	HGNC:11528	NK-3 receptor selective antagonist compounds, pharmaceutical composition and methods for use in NK-3 receptors mediated disorders	Ogeda SA	11/20/20	2D 3D TSV
US10550125	10	5	HGNC:2459 HGNC:2457	Prodrugs of imidazotriazine compounds as CK2 inhibitors	Bristol-Myers Squibb Company	11/20/20	2D 3D TSV
US10550105	855	803		Pyridazinones as PARP7 inhibitors	Ribon Therapeutics Inc.	11/20/20	2D 3D TSV
US10577308	216	36	HGNC:10588 HGNC:10596	Sodium channel modulators	The Florey Institute; The University of Melbourne	11/20/20	2D 3D TSV
US10576064	115	107		Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors	Boehringer Ingelheim International GmbH	11/20/20	2D 3D TSV
US10577363	985	980		Substituted piperidine compounds	EPIZYME, INC.	11/20/20	2D 3D TSV
US10550096	5	3	HGNC:10894	Tetrahydroisoquinolines as PRMT5 inhibitors	CTXT PTY LTD	11/20/20	2D 3D TSV
US10556883	18	9	HGNC:195 HGNC:7155	Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine and cosmetics	GALDERMA RESEARCH & DEVELOPMENT	11/13/20	2D 3D TSV
US10556902	124	122	HGNC:7056	Glycosidase inhibitors	Asceneuron SA	11/13/20	2D 3D TSV
US10556885	634	302	HGNC:4617 HGNC:3091	Isoquinolin-3-YL carboxamides and preparation and use thereof	Samumed, LLC	11/13/20	2D 3D TSV
US10556892	65	37	HGNC:736	Piperazinyl methanone NAAA inhibitors	The Regents of the University of California; Fondazione Istituto Italiano di Technologia	11/13/20	2D 3D TSV
US10556908	120	119	HGNC:29079	Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors	Incyte Corporation	11/13/20	2D 3D TSV
US10556914	100	100	HGNC:4507	Substituted isoxazolopyridazinones and isothiazolopyridazinones and methods of use	ABBVIE INC.; ABBVIE DEUTSCHLAND GMBH & CO. KG	11/13/20	2D 3D TSV
US10555944	1229	556		Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors	Eli Lilly and Company	11/13/20	2D 3D TSV
US10556900	75	71	HGNC:8031	TrkA kinase inhibitors, compositions and methods thereof	Merck Sharp & Dohme Corp.	11/13/20	2D 3D TSV
US10538491	153	153		4,5-substituted picolinamide and picolinonitrile metabotropic glutamate receptor 2 negative allosteric modulators	Vanderbilt University	11/09/20	2D 3D TSV
US10538523	3	3	HGNC:4076	4-(biphen-3-yl)-1H-pyrazolo[3,4-c]pyridazine derivatives of formula (I) as GABA receptor modulators for use in the treatment of epilepsy and pain	PFIZER LIMITED	11/09/20	2D 3D TSV
US10538528	107	46	HGNC:391 HGNC:10430	5H-pyrrolo[2,3-D]pyrimidin-6(7H)-one derivative	Taiho Pahrmaceutical Co., Ltd.	11/09/20	2D 3D TSV
US10538497	213	208	HGNC:6059	Compounds as indoleamine 2,3-dioxygenase inhibitors	Merck Sharp & Dohme Corp.	11/09/20	2D 3D TSV
US10538496	192	188	HGNC:19086	Methods using HDAC11 inhibitors	FORMA Therapeutics, Inc.; H. Lee Moffitt Cancer Center and Research Institute, Inc.	11/09/20	2D 3D TSV
US10537571	140	66	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Pyrimidine FGFR4 inhibitors	EISAI R&D MANAGEMENT CO., LTD.	11/09/20	2D 3D TSV
US10538517	40	39	HGNC:3688	Quinolone derivatives as FGFR inhibitors	Principia Biopharma, Inc.	11/09/20	2D 3D TSV
US10538508	126	61	HGNC:17432 HGNC:1936	Substituted amino triazoles useful as human chitinase inhibitors	OncoArendi Therapeutics S.A.	11/09/20	2D 3D TSV
US10550091	176	87	HGNC:7968	1,4,5-substituted 1,2,3-triazole analogues as antagonists of the pregnane X receptor	St. Jude Children''s Research Hospital	11/07/20	2D 3D TSV
US10550100	455	114	HGNC:7160 HGNC:195 HGNC:7159 HGNC:221	5-[3-[piperzin-1-yl]-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS 4 and 5 inhibitors for treating E.G. osteoarthritis	GALAPAGOS NV	11/07/20	2D 3D TSV
US10548313	35	34		Acetyl-CoA carboxylase modulators	Monsanto Technology LLC	11/07/20	2D 3D TSV
US10550080	137	49	HGNC:10593 HGNC:10597	Acyl sulfonamide NaV1.7 inhibitors	Bristol-Myers Squibb Company	11/07/20	2D 3D TSV
US10550073	35	25	HGNC:2623 HGNC:6876	Benzamide derivative	CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd.	11/07/20	2D 3D TSV
US10550089	124	62	HGNC:3538	Inhibitors of protease-activated receptor-2	Heptares Therapeutics Limited	11/07/20	2D 3D TSV
US10544132	133	130	HGNC:6973	Isoindolinone inhibitors of the MDM2-p53 interaction having anticancer activity	ASTEX THERAPEUTICS LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED	11/07/20	2D 3D TSV
US10548897	8	8		KSR antagonists	Icahn School of Medicine at Mount Sinai	11/07/20	2D 3D TSV
US10544136	207	163	HGNC:3167 HGNC:3165	Modulators of sphingosine phosphate receptors	The Scripps Research Institute	11/07/20	2D 3D TSV
US10550099	297	182		Quinolinone pyrimidines compositions as mutant-isocitrate dehydrogenase inhibitors	Forma Therapeutics, Inc.	11/07/20	2D 3D TSV
US10548896	122	119	HGNC:29079	Treatment of relapsed and/or refractory solid tumors and non-Hodgkin's lymphomas	Celgene Quanticel Research, Inc.	11/07/20	2D 3D TSV
US10544143	3210	878	HGNC:15633 HGNC:15631 HGNC:15632	4-azaindole compounds	Bristol-Myers Squibb Company	11/02/20	2D 3D TSV
US10544152	10	9	HGNC:5295	5-HT2CR agonist analogs	The Board of Regents of The University of Texas System; University of Houston System	11/02/20	2D 3D TSV
US10544146	4	1		Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors	FEDORA PHARMACEUTICALS INC.	11/02/20	2D 3D TSV
US10544151	11	11	HGNC:6307	Compounds and uses thereof	Kala Pharmaceuticals, Inc.	11/02/20	2D 3D TSV
US10544141	90	76		Derivatives and methods of treating hepatitis B infections	NOVIRA THERAPEUTICS, INC.	11/02/20	2D 3D TSV
US10544133	168	150	HGNC:17967	Heteroaryl substituted pyridyl compounds useful as kinase modulators	Bristol-Myers Squibb Company	11/02/20	2D 3D TSV
US10533001	238	213	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:11491	Inhibitors of protein kinases	PORTOLA PHARMACEUTICALS, INC.	11/02/20	2D 3D TSV
US10544128	732	235	HGNC:4617 HGNC:3091	Isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	11/02/20	2D 3D TSV
US10544130	1497	489		Metallo-beta-lactamase inhibitors	Merck Sharp & Dohme Corp.	11/02/20	2D 3D TSV
US10544147	185	117	HGNC:8977	Purine inhibitors of human phosphatidylinositol 3-kinase delta	Merck Sharp & Dohme Corp.	11/02/20	2D 3D TSV
US10533010	416	376	HGNC:6943 HGNC:992 HGNC:990	Substituted indole Mcl-1 inhibitors	Vanderbilt University	11/02/20	2D 3D TSV
US10544126	111	107		Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases	TAKEDA PHARMACEUTICAL COMPANY LIMITED	11/02/20	2D 3D TSV
US10532048	12	12	HGNC:1113	Tetrahydroisoquinolin-1-one derivative or salt thereof	Seldar Pharma Inc.	11/02/20	2D 3D TSV
US10544095	38	38	HGNC:11708	3-indol substituted derivatives, pharmaceutical compositions and methods for use	Pfizer Inc.; iTeos Therapeutics	11/01/20	2D 3D TSV
US10544117	30	30	HGNC:5302	5-hydroxytryptamine receptor 7 activity modulators and their method of use	Temple University—Of The Commonwealth System of Higher Education	11/01/20	2D 3D TSV
US10543221	20	13		Beta-lactamase inhibitors, formulations, and uses thereof	University of South Florida; The Regents of the University of California	11/01/20	2D 3D TSV
US10544120	343	331	HGNC:19679	Biaryl kinase inhibitors	Bristol-Myers Squibb Company	11/01/20	2D 3D TSV
US10544106	98	96	HGNC:1133	Certain chemical entities, compositions, and methods	NEUPHARMA, INC.	11/01/20	2D 3D TSV
US10544104	437	141	HGNC:4840 HGNC:11283 HGNC:76	Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases	UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR CO	11/01/20	2D 3D TSV
US10543207	74	73		Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders	ARDELYX, INC.	11/01/20	2D 3D TSV
US10544075	8	4	HGNC:11799 HGNC:11796	Derivatives of sobetirome	OREGON HEALTH & SCIENCE UNIVERSITY	11/01/20	2D 3D TSV
US10543198	75	75	HGNC:29079	Inhibitor of lysine specific demethylase-1	Celgene Quanticel Research, Inc.	11/01/20	2D 3D TSV
US10543199	18	5	HGNC:427	Macrocycle and composition comprising thereof	Shenzhen TargetRx, Inc.	11/01/20	2D 3D TSV
US10543194	6	6		Organic compounds	INTRA-CELLULAR THERAPIES, INC.	11/01/20	2D 3D TSV
US10544110	36	35	HGNC:644	Small molecule inhibitors of the nuclear translocation of androgen receptor for the treatment of castration-resistant prostate cancer	University of Pittsburgh—Of the Commonwealth System of Higher Education	11/01/20	2D 3D TSV
US10544113	206	201	HGNC:5302	Thiazolidinone compounds and use thereof	National Health Research Institute; Regents of the University of Minnesota	11/01/20	2D 3D TSV
US10543183	12	6	HGNC:7966 HGNC:7965	Treatment and diagnosis of melanoma	The Rockefeller University	11/01/20	2D 3D TSV
US10543213	122	118	HGNC:29079	Treatment of relapsed and/or refractory solid tumors and non-hodgkin's lymphomas	Celgene Quanticel Research, Inc.	11/01/20	2D 3D TSV
US10526325	98	57	HGNC:8810	Bicyclic heterocyclic derivatives	Merck Patent GmbH	10/25/20	2D 3D TSV
US10526329	367	214	HGNC:3357	Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders	GALAPAGOS NV	10/25/20	2D 3D TSV
US10526336	212	98	HGNC:4849 HGNC:4848	Fused heteroaryl derivatives as orexin receptor antagonists	Merck, Sharp & Dohme Corp.	10/25/20	2D 3D TSV
US10526330	112	16	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	JAK kinase inhibitor compounds for treatment of respiratory disease	Theravance Biopharma R&D IP, LLC	10/25/20	2D 3D TSV
US10525036	90	58	HGNC:6877 HGNC:6871	Spirocyclic compounds	Recurium IP Holdings, LLC	10/25/20	2D 3D TSV
US10513534	17	11		2′-chloro nucleoside analogs for HCV infection	IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER	10/24/20	2D 3D TSV
US10513522	84	41	HGNC:6190 HGNC:6192	Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as JAK inhibitors	Incyte Corporation; Incyte Holdings Corporation	10/24/20	2D 3D TSV
US10512634	132	40	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:19086 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:4854 HGNC:4853 HGNC:18128	Benzimidazole derivates useful as inhibitors of mammalian histone deacetylase activity	KANCERA AB	10/24/20	2D 3D TSV
US10513493	31	31	HGNC:29079	Cyclopropylamines as LSD1 inhibitors	Incyte Corporation	10/24/20	2D 3D TSV
US10513512	7	7	HGNC:3023	Flavanone derivatives, and preparation method and use thereof	Xuanwu Hospital of Capital Medical University	10/24/20	2D 3D TSV
US10513523	249	246	HGNC:4571	Imidazopyrazines and pyrazolopyrimidines and their use as AMPA receptor modulators	Janssen Pharmaceutica NV	10/24/20	2D 3D TSV
US10513499	22	22	HGNC:19288	Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase	TES Pharma S.r.l.	10/24/20	2D 3D TSV
US10513518	46	38	HGNC:6255	Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp.	10/24/20	2D 3D TSV
US10512644	125	47	HGNC:8153 HGNC:8154 HGNC:8156	Oligomer-opioid agonist conjugates	Inheris Pharmaceuticals, Inc.	10/24/20	2D 3D TSV
US10513524	10	5	HGNC:8795 HGNC:8775	PDE9 inhibitors with imidazo triazinone backbone and imidazo pyrazinone backbone for treatment of peripheral diseases	H. LUNDBECK A/S	10/24/20	2D 3D TSV
US10513514	34	32	HGNC:20001	Piperidine compounds as PCSK9 inhibitors	SHENZHEN SALUBRIS PHARM CO LTD.	10/24/20	2D 3D TSV
US10513507	13	11	HGNC:12630	Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors	FORMA Therapeutics, Inc.	10/24/20	2D 3D TSV
US10513520	6	6	HGNC:4912	Sulfamide and sulfamate inhibitors of hHint1	Regents of the University of Minnesota	10/24/20	2D 3D TSV
US10519167	3	3	HGNC:10894	3-oxa-8-azabicyclo[3.2.1]octane derivatives and their use in the treatment of cancer and hemoglobinopathies	CTXT PTY LTD	10/19/20	2D 3D TSV
US10519153	34	11	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Fused imidazo-piperidine JAK inhibitors	Theravance Biopharma R&D IP, LLC	10/19/20	2D 3D TSV
US10519177	802	696		Heterocyclic compounds and uses thereof	Plexxikon Inc.	10/19/20	2D 3D TSV
US10519118	167	165	HGNC:29079	KDM1A inhibitors for the treatment of disease	Imago Biosciences, Inc.	10/19/20	2D 3D TSV
US10517849	9	9	HGNC:29079	LSD1 inhibitors and medical uses thereof	Constellation Pharmaceuticals, Inc.	10/19/20	2D 3D TSV
US10517872	30	15	HGNC:17967	Pyridazinone macrocycles as IRAK inhibitors and uses thereof	Merck Patent GmbH	10/19/20	2D 3D TSV
US10519163	252	89	HGNC:7027 HGNC:12446	Pyrrolopyrimidine derivatives as TAM inhibitors	Incyte Corporation	10/19/20	2D 3D TSV
US10517878	110	106	HGNC:6871	Serine/threonine kinase inhibitors	GENENTECH, INC.	10/19/20	2D 3D TSV
US10517858	327	107	HGNC:19310 HGNC:8987	Thiazolecarboxamides and pyridinecarboxamide compounds useful as PIM kinase inhibitors	Incyte Holdings Corporation; Incyte Corporation	10/19/20	2D 3D TSV
US10512632	603	190	HGNC:8775 HGNC:8774 HGNC:8776	1 H-pyrazolo[4,3-B]pyridines as PDE1 inhibitors	H. Lundbeck A/S	10/18/20	2D 3D TSV
US10508119	51	49	HGNC:436	Pyrazole derivatives useful as 5-lipdxygenase activating protein (FLAP) inhibitors	ASTRAZENECA AB	10/18/20	2D 3D TSV
US10508120	1366	1156		TYK2 inhibitors and uses thereof	Nimbus Lakshimi, Inc.	10/18/20	2D 3D TSV
US10508115	134	73	HGNC:15631 HGNC:6018	Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor	Bristol-Myers Squibb Company	10/18/20	2D 3D TSV
US10508104	531	514	HGNC:339	6-hydroxy-5-(phenyl/heteroarylsulfonyl)pyrimidin-4(1H)-one as APJ agonists	Bristol-Myers Squibb Company	10/12/20	2D 3D TSV
US10501438	16	16	HGNC:13575	Aryl-substituted dihydroquinolinones, their preparation and their use as pharmaceuticals	Neomed Institute	10/12/20	2D 3D TSV
US10508103	138	51	HGNC:11892	Benzimidazole-linked indole compound acting as novel divalent IAP antagonist	MEDSHINE DISCOVERY INC.	10/12/20	2D 3D TSV
US10508109	306	303	HGNC:17287	Bicyclic compound and use thereof for inhibiting SUV39H2	ONCOTHERAPY SCIENCE, INC.	10/12/20	2D 3D TSV
US10501436	207	36	HGNC:171 HGNC:1076 HGNC:172 HGNC:175	Compounds and methods of use	Medivation Technologies LLC	10/12/20	2D 3D TSV
US10500194	30	30		Covalent small molecule DCN1 inhibitors and therapeutic methods using the same	THE REGENTS OF THE UNIVERSITY OF MICHIGAN	10/12/20	2D 3D TSV
US10501473	12	12		Fused heterocyclic ring compounds and method of treating retinal disease using same	THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC)	10/12/20	2D 3D TSV
US10501467	122	66	HGNC:270 HGNC:272 HGNC:15677 HGNC:273	Fused tetra or penta-cyclic dihydrodiazepinocarbazolones as PARP inhibitors	BEIGENE, LTD.	10/12/20	2D 3D TSV
US10501440	42	26	HGNC:6371	Heteroarylcarboxamide derivatives as plasma kallikrein inhibitors	Boehringer Ingelheim International GmbH	10/12/20	2D 3D TSV
US10508105	148	117	HGNC:4596	Indazole compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction	Vanderbilt University	10/12/20	2D 3D TSV
US10508102	28	13	HGNC:11892	Inhibitors of cellular necrosis and related methods	President and Fellows of Harvard College; Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences	10/12/20	2D 3D TSV
US10508099	951	303	HGNC:4617 HGNC:3091	Isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	10/12/20	2D 3D TSV
US10501452	149	37	HGNC:3023	Lactam compound derivative and application thereof	NHWA PHARMA. CORPORATION	10/12/20	2D 3D TSV
US10508107	58	20	HGNC:6251 HGNC:17734 HGNC:11049	Morpholine derivative	Hoffmann-La Roche Inc.	10/12/20	2D 3D TSV
US10501451	28	15		Selective NR2B antagonists	Bristol-Myers Squibb Company	10/12/20	2D 3D TSV
US10501411	555	283		Substituted benzamides	Hoffmann-La Roche Inc.	10/12/20	2D 3D TSV
US10501458	72	37	HGNC:11708 HGNC:6059	Substituted bicyclic fused ring compounds as indoleamine-2,3-dioxygenase inhibitors	Iomet Pharma Ltd.; Merck Sharp & Dohme Corp.	10/12/20	2D 3D TSV
US10501449	69	68	HGNC:6255	Substituted nitrogen containing compounds	Bristol-Myers Squibb Company	10/12/20	2D 3D TSV
US10501435	18	5	HGNC:4177	Substituted quinazoline compounds and uses thereof for modulating glucocerebrosidase activity	Northwestern University	10/12/20	2D 3D TSV
US10508108	131	121		Tricyclic compounds as inhibitors of mutant IDH enzymes	Merck Sharp & Dohme Corp.	10/12/20	2D 3D TSV
US10501466	33	33	HGNC:12757	WDR5 inhibitors and modulators	Vanderbilt University	10/12/20	2D 3D TSV
US10507215	42	14	HGNC:6833 HGNC:6834 HGNC:404	Compounds for the treatment of addiction	Amygdala Neurosciences, Inc.	10/02/20	2D 3D TSV
US10508088	214	193	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:19086 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:4854 HGNC:4853 HGNC:18128	Methods using HDAC11 inhibitors	FORMA Therapeutics, Inc.	10/02/20	2D 3D TSV
US10494380	32	31	HGNC:2623	Nitrogen-containing tricyclic derivatives having HIV replication inhibitory activity	Shionogi & Co., Ltd.	10/02/20	2D 3D TSV
US10508086	253	218	HGNC:8605 HGNC:270	PARG inhibitory compounds	Cancer Research Technology Limited	10/02/20	2D 3D TSV
US10507209	33	11	HGNC:3432 HGNC:3430 HGNC:3236	Quinazoline derivatives substituted by aniline, preparation method and use thereof	XUANZHU PHARMA CO, LTD.	10/02/20	2D 3D TSV
US10508098	13	13	HGNC:12630	Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors	FORMA Therapeutics, Inc.	10/02/20	2D 3D TSV
US10493060	92	59	HGNC:6877 HGNC:6871	Spirocyclic compounds	Recurium IP Holdings, LLC	10/02/20	2D 3D TSV
US10508083	266	256	HGNC:4849	Substituted piperidine compound and use thereof	Takeda Pharmaceutical Company Limited	10/02/20	2D 3D TSV
US10494376	120	118	HGNC:10894	Tetrahydroisoquinoline derived PRMT5-inhibitors	CTXT PTY. LTD.	10/02/20	2D 3D TSV
US10479795	816	404	HGNC:8978 HGNC:8977	Substituted imidazo[2,1-f][1,2,4]triazines, substituted imidazo[1,2-a]pyridines and substituted imidazo[1,2-b]pyridazines as PI3K-gamma inhibitors	Incyte Corporation	09/26/20	2D 3D TSV
US10479803	38	29	HGNC:6190 HGNC:8977	Bicyclic heteroarylaminoalkyl phenyl derivatives as PI3K inhibitors	Incyte Corporation	09/25/20	2D 3D TSV
US9975885	182	31		Broad-spectrum non-covalent coronavirus protease inhibitors	PURDUE RESEARCH FOUNDATION	09/25/20	2D 3D TSV
US10479788	156	155	HGNC:12401	Compounds that inhibit MPS1 kinase	Cancer Research Technology Limited	09/25/20	2D 3D TSV
US10479794	202	66	HGNC:8772	Cyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxyamide	Boehringer Ingelheim International GmbH	09/25/20	2D 3D TSV
US10478426	8	7		Enhancer of Zeste Homolog 2 inhibitors	GLAXOSMITHKLINE LLC	09/25/20	2D 3D TSV
US10479798	32	32	HGNC:3009	Six-membered ring benzo derivatives as DPP-4 inhibitor and use thereof	EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES	09/25/20	2D 3D TSV
US10479784	603	576	HGNC:882	Substituted pyrazin-2-amines as inhibitors of ATR kinase	VERTEX PHARMACEUTICALS INCORPORATED	09/25/20	2D 3D TSV
US10478424	2922	955	HGNC:15633	[1,2,4]triazolo[1,5-a]pyridinyl substituted indole compounds	Bristol-Myers Squibb Company	09/24/20	2D 3D TSV
USRE47740	6	6	HGNC:6027	Aminopyridinecarboxamides as CXCR2 modulators	Syntrix Biosystems Inc.	09/20/20	2D 3D TSV
US10487111	12	12	HGNC:10906	IBAT inhibitors for the treatment of liver diseases	Albireo AB	09/20/20	2D 3D TSV
US10487086	77	77	HGNC:3529	Macrocycles as factor XIa inhibitors	Bristol-Myers Squibb Company	09/20/20	2D 3D TSV
US10485800	204	202	HGNC:6850	Mixed lineage kinase inhibitors for HIV/AIDS therapies	The University of Rochester; Board of Regents of the University of Nebraska	09/20/20	2D 3D TSV
US10487087	38	25	HGNC:4324	Positive allosteric modulators of the GLP-1 receptor	Vanderbilt University	09/20/20	2D 3D TSV
US10487092	126	124		Pyrazolopyridinamines as MKNK1 and MKNK2 inhibitors	BAYER PHARMA AKTIENGESELLSCHAFT	09/20/20	2D 3D TSV
US10485803	106	42	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyrimidine compounds as JAK kinase inhibitors	THERAVANCE BIOPHARMA R&D IP, LLC	09/20/20	2D 3D TSV
US10487083	60	15		Small molecule inhibitors of the JAK family of kinases	Janssen Pharmaceutica NV	09/20/20	2D 3D TSV
US10478423	74	37	HGNC:6342 HGNC:3765	Substituted indazole derivatives active as kinase inhibitiors	NERVIANO MEDICAL SCIENCES S.R.L.	09/20/20	2D 3D TSV
US10487084	22	13	HGNC:15631 HGNC:6018	Toll-like receptor 7 (TLR7) agonists having a heterobiaryl moiety, conjugates thereof, and methods and uses therefor	Bristol-Myers Squibb Company	09/20/20	2D 3D TSV
US10472354	838	389	HGNC:8534	1,3-thiazol-2-yl substituted benzamides	Bayer Aktiengesellschaft	09/14/20	2D 3D TSV
US10472358	196	86		1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins	Incyte Corporation	09/14/20	2D 3D TSV
US10472324	9	9		2-cyano-3-cyclopropyl-3-hydroxy-N-aryl-thioacrylamide derivatives	ALGIAX PHARMACEUTICALS GMBH	09/14/20	2D 3D TSV
US10472364	86	80	HGNC:8021	Ectonucleotidase inhibitors and methods of use thereof	Calithera Biosciences, Inc.	09/14/20	2D 3D TSV
US10472344	12	7	HGNC:3529 HGNC:6357	Factor XIa inhibitors	Merck Sharp & Dohme Corp.	09/14/20	2D 3D TSV
US10472367	5	5	HGNC:7029	Imidazo[1,2-B][1,2,4]triazines as c-Met inhibitors	INCYTE INCORPORATION; INCYTE HOLDINGS CORPORATION	09/14/20	2D 3D TSV
US10464947	570	277	HGNC:13575	Tricyclic heterocycles as BET protein inhibitors	Incyte Holdings Corporation; Incyte Corporation	09/09/20	2D 3D TSV
US10464911	88	76	HGNC:4852 HGNC:14064	1,3,4-oxadiazole sulfamide derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same	Chong Kun Dang Pharmaceutical Corp.	09/08/20	2D 3D TSV
US10464927	98	49	HGNC:1777 HGNC:1773	2,4-disubstituted pyrimidines as CDK inhibitors	Shanghai Xunhe Pharmaceutical Technology Co. Ltd.	09/08/20	2D 3D TSV
US10464928	3	3	HGNC:550	Amino pyrimidine SSAO inhibitors	Eli Lilly and Company	09/08/20	2D 3D TSV
US10463675	468	113	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Aminopyrimidinyl compounds	Pfizer Inc.	09/08/20	2D 3D TSV
US10457703	240	234	HGNC:7967	Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof	Enanta Pharmaceuticals, Inc.	09/08/20	2D 3D TSV
US10464907	29	29		Compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof, and medical use thereof	INDUSTRY ACADEMIC COOPERATION FOUNDATION KEIMYUNG UNIVERSITY	09/08/20	2D 3D TSV
US10464902	10	10	HGNC:6307	Multi-tyrosine kinase inhibitors derivatives and methods of use	Ontogenesis, LLC	09/08/20	2D 3D TSV
US10464918	11	11	HGNC:11331	Process of making somatostatin modulators	CRINETICS PHARMACEUTICALS, INC.	09/08/20	2D 3D TSV
US10463663	68	66	HGNC:2671	Pyridazinone compounds and their use as DAAO inhibitors	Takeda Pharmaceutical Company Limited	09/08/20	2D 3D TSV
US10464919	346	184	HGNC:270 HGNC:19297 HGNC:11940	Tricyclic derivative compound, method for preparing same, and pharmaceutical composition comprising same	Je Il Pharmaceutical Co., Ltd.	09/08/20	2D 3D TSV
US10457637	170	120	HGNC:5981	Benzenesulfonamide derivatives as inverse agonists of retinoid-related orphan receptor gamma (RORγ(T))	GALDERMA RESEARCH & DEVELOPMENT	09/07/20	2D 3D TSV
US10457678	10	10	HGNC:195	Substituted pyrrolo[2,3-b]pyridines as inhibitors of cellular necroptosis	Institut National de la Sante et de la Recherche Medicale (INSERM); Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Universite Claude Bernard Lyon 1	09/07/20	2D 3D TSV
US10457681	16	11	HGNC:15631 HGNC:6018	Toll-like receptor 7 (TLR7) agonists having a tricyclic moiety, conjugates thereof, and methods and uses therefor	Bristol_Myers Squibb Company	09/07/20	2D 3D TSV
US10457686	14	7	HGNC:2160 HGNC:2159	[1,2,3]triazolo[4,5-D]pyrimidine derivatives	Hoffmann-La Roche Inc.	09/07/20	2D 3D TSV
US10457685	76	38	HGNC:2160 HGNC:2159	[1,2,3]triazolo[4,5-D]pyrimidine derivatives with affinity for the type-2 cannabinoid receptor	Hoffmann-La Roche Inc.	09/07/20	2D 3D TSV
US10457684	30	15	HGNC:2160 HGNC:2159	[1,2,3]triazolo[4,5-d]pyrimidine derivatives	Hoffmann-La Roche Inc.	09/07/20	2D 3D TSV
US10450301	191	190	HGNC:6857	Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	08/31/20	2D 3D TSV
US10450313	162	54	HGNC:3690 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR inhibitors	Incyte Holdings Corporation	08/31/20	2D 3D TSV
US10450298	7	6	HGNC:3357	PET Imaging agents	Novartis AG	08/31/20	2D 3D TSV
US10450297	341	328		Sulfonyl amide derivatives for the treatment of abnormal cell growth	Pfizer, Inc.	08/31/20	2D 3D TSV
US10450321	14	7	HGNC:2160 HGNC:2159	[1,2,3]triazolo[4,5-D]pyrimidine derivatives	Hoffmann-La Roche Inc.	08/31/20	2D 3D TSV
US10450296	510	168	HGNC:19310 HGNC:8987	Heterocyclic compounds useful as Pim kinase inhibitors	Incyte Corporation	08/30/20	2D 3D TSV
US10457672	128	128	HGNC:15983	γ-diketones as Wnt/β-catenin signaling pathway activators	Samumed, LLC	08/24/20	2D 3D TSV
US10323028	67	55		1,3,4-thiadiazole compounds and their use in treating cancer	AstraZeneca AB	08/24/20	2D 3D TSV
US10442759	21	21		1-sulfonamido-4-aryloxy compounds, and preparation method and medicinal application thereof	CHINA PHARMACEUTICAL UNIVERSITY	08/24/20	2D 3D TSV
US10457647	40	40	HGNC:1133	Amino pyrimidine derivatives	Novartis AG	08/24/20	2D 3D TSV
US10323037	118	118	HGNC:1133	Aminopyridazinone compounds as protein kinase inhibitors	JIANGSU HENGRUI MEDICINE CO., LTD.	08/24/20	2D 3D TSV
US10435408	19	19	HGNC:5302	Azepine derivatives as 5-HT7 receptor modulators	Korea Institute of Science and Technology	08/24/20	2D 3D TSV
US10377755	15	15	HGNC:990	BCL-2 inhibitors	Newave Pharmaceutical Inc.	08/24/20	2D 3D TSV
US10442772	248	182		Benzimidazol-2-amines as mIDH1 inhibitors	BAYER PHARMA AKTIENGESELLSCHAFT	08/24/20	2D 3D TSV
US10457669	927	912	HGNC:6871	Benzolactam compounds as protein kinase inhibitors	OTSUKA PHARMACEUTICAL CO., LTD.	08/24/20	2D 3D TSV
US10307425	116	115		Compositions and methods for treating toxoplasmosis, cryptosporidiosis and other apicomplexan protozoan related diseases	University of Washington	08/24/20	2D 3D TSV
US10376513	368	348	HGNC:8977	Heterocyclylamines as PI3K inhibitors	Incyte Holdings Corporation	08/24/20	2D 3D TSV
US10457675	96	86	HGNC:14065	Histone deacetylase inhibitors and compositions and methods of use thereof	CHDI Foundation, Inc.	08/24/20	2D 3D TSV
US10329260	302	298	HGNC:6371	Human plasma kallikrein inhibitors	BioCryst Pharmaceuticals, Inc.	08/24/20	2D 3D TSV
US10457677	471	137	HGNC:8979 HGNC:8978 HGNC:795 HGNC:3942	Imidazolonylquinolines and the use thereof as ATM kinase inhibitors	Merck Patent GmbH	08/24/20	2D 3D TSV
US10323013	21	21	HGNC:3449	Inhibitors of the IRE-1/XBP-1 pathway and methods of using thereof	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.	08/24/20	2D 3D TSV
US10441590	9	2	HGNC:5302 HGNC:5301 HGNC:3023 HGNC:5286 HGNC:5294	Methods for treating pulmonary hypertension	Reviva Pharmaceuticals, Inc.	08/24/20	2D 3D TSV
US10399948	138	60		Negative allosteric modulators of metabotropic glutamate receptor 3	Vanderbilt University	08/24/20	2D 3D TSV
US10456385	31	31	HGNC:1960	Pharmaceutical composition comprising pyridone derivatives	SK BIOPHARMACEUTICALS CO., LTD.	08/24/20	2D 3D TSV
US10399980	544	539	HGNC:12607	Purinones as ubiquitin-specific protease 1 inhibitors	FORMA Therapeutics, Inc.	08/24/20	2D 3D TSV
US10442808	127	124		Pyrazolo pyrimidine derivatives and their use as MALT1 inhbitors	Novartis AG	08/24/20	2D 3D TSV
US10329300	80	80	HGNC:3430	Pyrazolo[3,4-d]pyrimidine compound or salt thereof	TAIHO PHARMACEUTICAL CO., LTD.	08/24/20	2D 3D TSV
US10442810	438	145	HGNC:7027 HGNC:12446	Pyrrolotriazine compounds as TAM inhibitors	Incyte Corporation	08/24/20	2D 3D TSV
US10301261	220	104	HGNC:10260	Substituted indoles as modulators of ROR-gamma	Vitae Pharmaceuticals, LLC	08/24/20	2D 3D TSV
US10441581	2116	815		Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors	Array Biopharma Inc.	08/24/20	2D 3D TSV
US10456394	62	18	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:19086 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:4854 HGNC:4853 HGNC:18128	Tetrahydroquinoline substituted hydroxamic acids as selective histone deacetylase 6 inhibitors	THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS	08/24/20	2D 3D TSV
US10457654	393	239	HGNC:10597	Therapeutic compounds and methods of use thereof	GENENTECH, INC.	08/24/20	2D 3D TSV
US10442819	556	509		Tricyclic compounds as inhibitors of mutant IDH enzymes	Merck Sharp & Dohme Corp.	08/24/20	2D 3D TSV
US10442803	546	273	HGNC:13575	Tricyclic heterocycles as bet protein inhibitors	Incyte Corporation	08/24/20	2D 3D TSV
US9951068	213	154	HGNC:6251 HGNC:550	Imidazo[4,5-C]pyridine and pyrrolo[2,3-C]pyridine derivatives as SSAO inhibitors	PROXIMAGEN LIMITED	08/19/20	2D 3D TSV
US10428066	213	155	HGNC:6251 HGNC:550	Imidazo[4,5-C]pyridine and pyrrolo[2,3-C]pyridine derivatives as SSAO inhibitors	PROXIMAGEN, LLC	08/19/20	2D 3D TSV
US10428044	491	480	HGNC:1148	3-amino-1,5,6,7-tetrahydro-4H-indol-4-ones	Bayer Pharma Aktiengesellschaft	08/17/20	2D 3D TSV
US10428063	47	46		4H-pyrrolo[3,2-C]pyridin-4-one derivatives	Bayer Pharma Aktiengesellschaft	08/17/20	2D 3D TSV
US10435406	8	5	HGNC:8154 HGNC:8156	6,7-cyclicmorphinan derivatives and use thereof	Purdue Pharma L.P.	08/17/20	2D 3D TSV
US10428108	98	93		Difluoroketamide derivatives	Hoffmann-La Roche Inc.	08/17/20	2D 3D TSV
US10428068	73	62	HGNC:5253 HGNC:1735	Fused amino pyridine as HSP90 inhibitors	Curis, Inc.	08/17/20	2D 3D TSV
US10428028	43	15	HGNC:4852 HGNC:4854 HGNC:4853	HDAC inhibitors	BIOMARIN PHARMACEUTICAL INC.	08/17/20	2D 3D TSV
US10428083	23	6	HGNC:268 HGNC:262 HGNC:263 HGNC:264	Heterocyclylmethyl-thienouracile as antagonists of the adenosine-A2B-receptor	BAYER PHARMA AKTIENGESELLSCHAFT	08/17/20	2D 3D TSV
US10426135	104	104		Methyl- and trifluromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof	Pfizer Inc.	08/17/20	2D 3D TSV
US10428024	85	52	HGNC:8810	Piperidinyl derivatives	MERCK PATENT GMBH	08/17/20	2D 3D TSV
US10428087	125	82	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Pyrimidinones as PI3K inhibitors	Incyte Corporation	08/17/20	2D 3D TSV
US10428074	130	69	HGNC:6190 HGNC:6192 HGNC:6193	Pyrrole heteroaryl ring derivative and method of use thereof	Jiangsu Hengrui Medicine Co., Ltd.	08/17/20	2D 3D TSV
US10428076	247	231		Soluble guanylate cyclase stimulators	Merck Sharp & Dohme Corp.	08/17/20	2D 3D TSV
US10428104	118	117	HGNC:10894	Substituted nucleoside derivatives useful as anticancer agents	Pfizer Inc.	08/17/20	2D 3D TSV
USRE47636	27	27	HGNC:2528	Substituted spirocycles	Boehringer Ingelheim International GmbH	08/17/20	2D 3D TSV
US10435415	152	43	HGNC:6192 HGNC:1133	Substituted tetrahydrocarbazole and carbazole carboxamide compounds	Bristol-Myers Squibb Company	08/17/20	2D 3D TSV
US10435407	170	169	HGNC:2730	Triaza-spirodecanones as DDR1 inhibitors	Hoffmann-La Roche Inc.	08/17/20	2D 3D TSV
US10435414	215	214	HGNC:8979	Tricyclic PI3K inhibitor compounds and methods of use	Genentech, Inc.	08/17/20	2D 3D TSV
US10435400	122	57	HGNC:3236	2,4-disubstituted phenylene-1,5-diamine derivatives and applications thereof, and pharmaceutical compositions and pharmaceutically acceptable compositions prepared therefrom	SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO. LTD.	08/16/20	2D 3D TSV
US10435396	47	47	HGNC:17967	2-substituted indazoles, methods for producing same, pharmaceutical preparations that contain same, and use of same to produce drugs	Bayer Pharma Aktiegesellschaft	08/16/20	2D 3D TSV
US10435392	28	13		Bipyrazole derivatives as JAK inhibitors	Incyte Corporation	08/16/20	2D 3D TSV
US10434101	94	47	HGNC:3236	Heterocyclic compounds and uses thereof	Celgene CAR LLC	08/16/20	2D 3D TSV
US10435355	26	13	HGNC:3553	Inhibitors of fatty acid amide hydrolase (FAAH) enzyme with improved oral bioavailability and their use as medicaments	The Regents of the University of California	08/16/20	2D 3D TSV
US10435361	318	118	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6876	Kinase inhibitors	Topivert Pharma Limited	08/16/20	2D 3D TSV
US10434085	15	14	HGNC:6859	Non-aromatic difluoro analogues of resorcylic acid lactones	University of North Carolina at Greensboro	08/16/20	2D 3D TSV
US10435398	70	33	HGNC:4849 HGNC:4848	Oxazole orexin receptor antagonists	Merck Sharp & Dohme Corp.	08/16/20	2D 3D TSV
US10435405	241	235	HGNC:6863	Pyrazolopyridine compounds and uses thereof	Incyte Corporation	08/16/20	2D 3D TSV
US10435369	304	268		Tricyclic sulfones as ROR gamma modulators	Bristol-Myers Squibb Company	08/16/20	2D 3D TSV
US10434112	188	179	HGNC:3827	Use of agonists of formyl peptide receptor 2 for treating dermatological diseases	ALLERGAN, INC.	08/16/20	2D 3D TSV
US10435379	9	9	HGNC:6018	[4-(1,3,3-trimethyl-2-OXO-3,4-dihydro-1H-quinoxalin-7-yl)phenoxy]ethyloxy compound or salt thereof	SANTEN PHARMACEUTICAL CO., LTD.	08/16/20	2D 3D TSV
US10421756	152	74	HGNC:4852 HGNC:4853	Heterobicyclic N-aminophenyl-amides as inhibitors of histone deacetylase	Rodin Therapeutics, Inc.	08/12/20	2D 3D TSV
US10421760	61	20	HGNC:6190 HGNC:6192 HGNC:6193	Pyrrolo[2,3-d]pyrimidine compound or salt thereof	TAIHO PHARMACEUTICAL CO., LTD.	08/12/20	2D 3D TSV
US10420768	72	22	HGNC:4586 HGNC:6251 HGNC:2625	Pyrrolopyrimidine derivatives as NR2B NMDA receptor antagonists	Rugen Holdings (Cayman) Limited	08/12/20	2D 3D TSV
US10421747	35	7	HGNC:6307 HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Quinoxaline derivatives useful as FGFR kinase modulators	ASTEX THERAPEUTICS LTD	08/12/20	2D 3D TSV
US10421750	47	47	HGNC:8157	Substituted morpholine derivatives having activity against pain	ESTEVE PHARMACEUTICALS, S.A.	08/12/20	2D 3D TSV
US10421742	516	252	HGNC:6371 HGNC:3529	Substituted oxopyridine derivatives	BAYER PHARMA AKTIENGESELLSCHAFT	08/12/20	2D 3D TSV
US10421722	9	9	HGNC:10936	Sulfur-containing compounds targeting vesicular acetylcholine transporter	Washington University	08/12/20	2D 3D TSV
US10421743	3	3	HGNC:10894	Tetrahydroisoquinolines as PRMT5 inhibitors	CTXT PTY LTD	08/12/20	2D 3D TSV
US10421765	101	99		Tetrahydropyrido[4,3-d]pyrimidine inhibitors of ATR kinase	Board of Regents, The University of Texas System	08/12/20	2D 3D TSV
US10414734	32	27		5-hydroxyalkylbenzimidazoles as mIDH1 inhibitors	BAYER PHARMA AKTIENGESELLSCHAFT	08/02/20	2D 3D TSV
US10413562	298	295	HGNC:1133	Compositions and methods for the production of pyrimidine and pyridine compounds with BTK inhibitory activity	Merck Patent GmbH	08/02/20	2D 3D TSV
US10414761	375	111	HGNC:6833 HGNC:6834 HGNC:29079	Cyclopropanamine compound and use thereof	Takeda Pharmaceutical Company Limited	08/02/20	2D 3D TSV
US10414797	100	23	HGNC:7173 HGNC:7174 HGNC:7176 HGNC:7155	Gelatinase inhibitors and use thereof	Iproteos S.L	08/02/20	2D 3D TSV
US10413545	98	97	HGNC:3594	Imidazolin-5-one derivative useful as FASN inhibitors for the treatment of cancer	Janssen Pharmaceutica NV	08/02/20	2D 3D TSV
US10413550	137	136		Isoxazole compounds as inhibitors of heat shock proteins	The Institute of Cancer Research	08/02/20	2D 3D TSV
US10414731	16	16	HGNC:3529	Substituted oxopyridine derivatives	BAYER PHARMA AKTIENGESELLSCHAFT	08/02/20	2D 3D TSV
US10414765	104	48	HGNC:6283 HGNC:6278	Substituted perhydropyrrolo[3,4-c]pyrrole derivatives and the use of same	BAYER PHARMA AKTIENGESELLSCHAFT	08/02/20	2D 3D TSV
US10399985	41	41	HGNC:8772	(Hetero)aryl imidazoles/pyrazoles for treatment of neurological disorders	Hoffmann-La Roche Inc.	07/27/20	2D 3D TSV
US10407409	426	417		6-(5-hydroxy-1H-pyrazol-1-yl)nicotinamide inhibitors of PHD	Takeda Pharmaceutical Company Limited	07/27/20	2D 3D TSV
US10407446	78	13	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:11393 HGNC:11390 HGNC:12401	Amino-triazolopyridine compounds and their use in treating cancer	AstraZeneca AB	07/27/20	2D 3D TSV
US10406136	18	9		Composition for suppressing neuraminidase activity comprising geranylated flavonoid derived from Paulownia tomentosa as active ingredient	INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY	07/27/20	2D 3D TSV
US10407441	14	7		Compositions and methods for treating neoplasia, inflammatory disease and other disorders	Dana-Farber Cancer Institute, Inc.	07/27/20	2D 3D TSV
US10399973	27	27	HGNC:550	Compounds I	BENEVOLENTAI CAMBRIDGE LIMITED	07/27/20	2D 3D TSV
US10407431	34	34	HGNC:15631	Compounds and compositions as toll-like receptor 7 agonists	Novartis AG	07/27/20	2D 3D TSV
US10407423	40	23	HGNC:2976 HGNC:14129	Compounds as inhibitors of DNA methyltransferases	FUNDACIÓN PARA LA INVESTIGACIÓN MÉDICA APLICADA	07/27/20	2D 3D TSV
US10399967	143	139	HGNC:6001	Compounds for inflammation and immune-related uses	PRCL RESEARCH INC.	07/27/20	2D 3D TSV
US10399976	220	153		Dihydropyrrolopyridine inhibitors of ROR-gamma	Vitae Pharmaceuticals, LLC	07/27/20	2D 3D TSV
US10398702	108	27		Dimeric compounds	Hoffmann-La Roche Inc.	07/27/20	2D 3D TSV
US10399961	15	15	HGNC:6371	Heteroarylcarboxamide derivatives as plasma kallikrein inhibitors	Boehringer Ingelheim International GmbH	07/27/20	2D 3D TSV
US10398706	9	7		Heteroaryldiazepine derivatives as RSV inhibitors	Enanta Pharmaceuticals, Inc.	07/27/20	2D 3D TSV
US10399979	92	23	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Janus kinase inhibitors and uses thereof	Purdue Research Foundation	07/27/20	2D 3D TSV
US10399991	64	64	HGNC:6221	Kv1.3 inhibitors and their medical applications	4SC AG	07/27/20	2D 3D TSV
US10399974	57	57	HGNC:12401	N2-phenyl-pyrido[3,4-D]pyrimidine-2, 8-diamine derivatives and their use as Mps1 inhibitors	Cancer Research Technology Limited	07/27/20	2D 3D TSV
US10399958	21	21	HGNC:9235	PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof	Mitobridge, Inc.	07/27/20	2D 3D TSV
US10399989	279	96	HGNC:1133 HGNC:3236	Pyrazolopyrimidine derivatives as BTK inhibitors for the treatment of cancer	Loxo Oncology, Inc.	07/27/20	2D 3D TSV
US10407433	124	111	HGNC:9922	Substituted 4-phenylpiperidines, their preparation and use	The Trustees of Columbia University In The City of New York	07/27/20	2D 3D TSV
US10399987	98	49	HGNC:11773	TGF beta receptor antagonists	Bristol-Myer Squibb Company	07/27/20	2D 3D TSV
US10399939	40	40	HGNC:3467	Tetrahydronaphthalene estrogen receptor modulators and uses thereof	Genentech, Inc.	07/27/20	2D 3D TSV
US10399945	74	68	HGNC:8031	Tetrahydronaphthyl urea derivative	MOCHIDA PHARMACEUTICAL CO., LTD.	07/27/20	2D 3D TSV
US10406157	4	2	HGNC:4515	Tetrahydropyridopyrazine modulators of GPR6	Takeda Pharmaceutical Company Limited	07/27/20	2D 3D TSV
US10398703	23	23	HGNC:6307	Therapeutic compounds and uses thereof	Kala Pharmaceuticals, Inc.	07/27/20	2D 3D TSV
US10407422	9	9	HGNC:7218	Triazolopyridine inhibitors of myeloperoxidase	Bristol-Myers Squibb Company	07/27/20	2D 3D TSV
US10399972	70	66		Tricyclic compounds as inhibitors of mutant IDH enzymes	Merck Sharp & Dohme Corp.	07/27/20	2D 3D TSV
US10392391	570	547	HGNC:882	Compounds useful as inhibitors of ATR kinase	Vertex Pharmaceuticals Incorporated	07/20/20	2D 3D TSV
US10392402	22	11	HGNC:10251 HGNC:10252	Heterocyclic compounds as kinase inhibitors	Translational Drug Development, LLC	07/20/20	2D 3D TSV
US10392376	131	119		Heterocyclic inhibitors of ATR kinase	Board of Regents, The University of Texas System	07/20/20	2D 3D TSV
US10392346	187	72	HGNC:11491 HGNC:11283 HGNC:4616	Kinase inhibitors	Topivert Pharma Limited	07/20/20	2D 3D TSV
US10392405	25	25	HGNC:17635	Macrocyclic immunomodulators	ChemoCentryx, Inc.	07/20/20	2D 3D TSV
US10391089	334	330	HGNC:29652	PRMT5 inhibitors and uses therof	Epizyme, Inc.	07/20/20	2D 3D TSV
US10392392	120	103	HGNC:6251	Substituted imidazo[1,2-B]pyridazines as protein kinase inhibitors	Tolero Pharmaceuticals, Inc.	07/20/20	2D 3D TSV
US10385022	323	323	HGNC:19680	3-amino-pyridines as GPBAR1 agonists	HOFFMANN-LA ROCHE INC.	07/13/20	2D 3D TSV
US10383871	19	19	HGNC:3553	Azetidine derivatives	Vernalis (R&D) Ltd.	07/13/20	2D 3D TSV
US10383880	247	237	HGNC:8846	Carbazole-containing sulfonamides as cryptochrome modulators	Synchronicity	07/13/20	2D 3D TSV
US10385066	36	35	HGNC:2843	Compounds as diacylglycerol acyltransferase inhibitors	GlaxoSmithKline LLC	07/13/20	2D 3D TSV
US10383850	23	23		Indazole and indole derivatives as inhibitors of retinoic acid related orphan receptor gamma (ROR gamma) for the treatment of immune-related diseases	ORCA PHARMACEUTICALS LIMITED	07/13/20	2D 3D TSV
US10377772	63	63	HGNC:18618	Macrocyclic LRRK2 kinase inhibitors	Oncodesign S.A.	07/13/20	2D 3D TSV
US10377763	48	23	HGNC:4849 HGNC:4848	Morphinan derivative and medical usage thereof	UNIVERSITY OF TSUKUBA	07/13/20	2D 3D TSV
US10385031	171	56	HGNC:4852 HGNC:4854 HGNC:4853	Substituted piperazines as selective HDAC1,2 inhibitors	REGENACY PHARMACEUTICALS, LLC	07/13/20	2D 3D TSV
US10385036	35	35		Sulfonamide-substituted indole modulators of RORC2 and methods of use thereof	Pfizer Inc.	07/13/20	2D 3D TSV
US10377768	112	91		Tetrahydronaphthyridine and related bicyclic compounds for inhibition of RORgamma activity and the treatment of disease	Lycera Corporation	07/13/20	2D 3D TSV
US10383835	72	25	HGNC:3401	Treatment of inflammatory disorders in non-human mammals	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA	07/13/20	2D 3D TSV
US10385052	28	7	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Tricyclic compound and JAK inhibitor	Nissan Chemical Corporation	07/13/20	2D 3D TSV
US10377770	457	419		Tricyclic compounds and compositions as kinase inhibitors	Novartis AG	07/13/20	2D 3D TSV
US10377742	493	490	HGNC:9377	AMPK-activating heterocyclic compounds and methods for using the same	Rigel Pharmaceuticals, Inc.	07/06/20	2D 3D TSV
US10370370	89	58	HGNC:5297 HGNC:1960	Aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors	Axovant Sciences GmbH	07/06/20	2D 3D TSV
US10370368	11	9	HGNC:6713	Aryl acylsulfonamides as BLT1 antagonists	Merck Sharp & Dohme Corp.	07/06/20	2D 3D TSV
US10370338	50	25	HGNC:15631 HGNC:15632	Benzazepine dicarboxamide compounds with tertiary amide function	Hoffmann-La Roche Inc.	07/06/20	2D 3D TSV
US10377729	5	5	HGNC:12405	Bis-furan derivatives as transthyretin (TTR) stabilizers and amyloid inhibitors for the treatment of familial amyloid polyneuropathy (FAP)	BSIM Therapeutics, S.A.	07/06/20	2D 3D TSV
US10370379	25	25	HGNC:8031	Compounds and compositions useful for treating disorders related to NTRK	BLUEPRINT MEDICINES CORPORATION	07/06/20	2D 3D TSV
US10370352	7	7	HGNC:6857	Cyclobutyl-imidazolidinone compounds	ELI LILLY AND COMPANY	07/06/20	2D 3D TSV
US10377717	104	104	HGNC:7967	Farnesoid X receptor agonists and uses thereof	METACRINE, INC.	07/06/20	2D 3D TSV
US10370388	85	82	HGNC:338	Heterocyclic compounds and methods of their use	NOVARTIS AG	07/06/20	2D 3D TSV
US10370375	84	28		Heterocyclyl-substituted cyclohexylsulfonamides as JAK inhibitors	Elanco Tiergesundheit AG	07/06/20	2D 3D TSV
US10377746	20	20		Indolin-2-one derivatives	Hoffmann-La Roche Inc.	07/06/20	2D 3D TSV
US10370339	48	47		N-Methylbenzimidazoles as mIDH1 inhibitors	BAYER PHARMA AKTIENGESELLSCHAFT	07/06/20	2D 3D TSV
US10370337	5	5		Oxy-cyanoquinolinone PDE9 inhibitors	Merck, Sharp & Dohme Corp.	07/06/20	2D 3D TSV
US10370336	6	5		Phenyl-cyanoquinolinone PDE9 inhibitors	Merck Sharp & Dohme Corp.	07/06/20	2D 3D TSV
US10377744	62	55	HGNC:3402	Potent soluble epdxide hydrolase inhibitors	Eicosis, LLC	07/06/20	2D 3D TSV
US10369153	249	142	HGNC:6190 HGNC:6192 HGNC:6193	Pyrrolopyrimidine compounds and uses thereof	HUTCHISON MEDIPHARMA LIMITED	07/06/20	2D 3D TSV
US10370360	160	40	HGNC:6342 HGNC:2730 HGNC:2731	Small-molecule inhibitors targeting discoidin domain receptor 1 and uses thereof	The Board of Regents of the University of Texas System	07/06/20	2D 3D TSV
US10377753	634	628	HGNC:4586	Substituted 4-azaindoles and their use as GluN2B receptor modulators	JANSSEN PHARMACEUTICA NV	07/06/20	2D 3D TSV
US10376531	17	17	HGNC:742	Substituted-6,8-dioxabicyclo[3.2.1]octane-2,3-diol compounds as targeting agents of ASGPR	Pfizer Inc.	07/06/20	2D 3D TSV
US10370333	169	163	HGNC:438	Sulfonamide compounds and uses as TNAP inhibitors	SANFORD-BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	07/06/20	2D 3D TSV
US10370387	196	96		Tricyclic fused thiophene derivatives as JAK inhibitors	Incyte Holdings Corporation	07/06/20	2D 3D TSV
US10376502	20	20		Alkylated imino sugars exhibiting glucosidase inhibition and their method of use	TBA	06/29/20	2D 3D TSV
US10364255	43	41		Heteroaromatic compounds as Vanin inhibitors	Boehringer Ingleheim International GmbH	06/29/20	2D 3D TSV
US10364242	3	1	HGNC:3553 HGNC:736 HGNC:735	Modulation of N-acylethanolamine-hydrolysing acid amidase (NAAA) for disease treatment	Fondazione Istituto Italiano di Tecnologia	06/29/20	2D 3D TSV
US10364238	188	92	HGNC:6371 HGNC:6357	N-((het) arylmethyl)-heteroaryl-carboxamides compounds as plasma kallikrein inhibitors	Kalvista Pharmaceuticals Limited	06/29/20	2D 3D TSV
US10364234	5	2	HGNC:6251 HGNC:6255	Pyridinecarboxamide derivatives, preparation method thereof and pharmaceutical uses thereof	Jiangsu Hengrui Medicine Co., Ltd.	06/29/20	2D 3D TSV
US10376504	6	6		Substituted quinolinones as PDE9 inhibitors	Merck Sharp & Dohme Corp	06/29/20	2D 3D TSV
US10376514	304	300	HGNC:8775	Therapeutic thiophene-, furan-, and pyridine-fused azolopyrimidin-5-(6H)-ones	Dart NeuroScience (Cayman) Ltd	06/29/20	2D 3D TSV
US10336729	95	95	HGNC:550	4-cyano-benzyl carbamimidoylcarbamate derivatives and their use as AOC3 inhibitors	Boehringer Ingelheim International GmbH	06/21/20	2D 3D TSV
US10336739	253	250	HGNC:339	4-hydroxy-3-(heteroaryl)pyridine-2-one APJ agonists	Bristol-Myers Squibb Co.	06/21/20	2D 3D TSV
US10357546	20	10	HGNC:7175 HGNC:7176	Acceleration of diabetic wound healing	University of Notre Dame du Lac	06/21/20	2D 3D TSV
US10336733	50	46	HGNC:6713	Aryl acylsulfonamides as BLT1 antagonists	Merk Sharp & Dohme Corp.	06/21/20	2D 3D TSV
US10358446	67	16	HGNC:6735 HGNC:1057 HGNC:1133 HGNC:6524	Bruton's tyrosine kinase inhibitors	ZIBO BIOPOLAR CHANGSHENG PHARMACEUTICAL CO., LTD.	06/21/20	2D 3D TSV
US10336724	38	19	HGNC:2671	D-amino acid oxidase inhibitors and therapeutic uses thereof	SyneuRx International (Taiwan) Corp.	06/21/20	2D 3D TSV
US10336755	23	23	HGNC:1133	Fused pyrazole derivatives, preparation method thereof, and use thereof in treatment of cancers, inflammation and immune diseases	Beijing Innocare Pharma Tech Co., Ltd.	06/21/20	2D 3D TSV
US10336775	181	174	HGNC:7056	Glycosidase inhibitors	Asceneuron SA	06/21/20	2D 3D TSV
US10358451	19	13	HGNC:11708 HGNC:6059	Heterocycles useful as IDO and TDO inhibitors	Hangzhou Innogate Pharma Co., Ltd.	06/21/20	2D 3D TSV
US10336727	237	79	HGNC:9886 HGNC:17071 HGNC:18039	Histone demethylase inhibitors	Celgene Quanticel Research Inc	06/21/20	2D 3D TSV
US10336734	12	3	HGNC:6192 HGNC:19297 HGNC:11283 HGNC:427	Inhibitors of ACK1/TNK2 tyrosine kinase	H. Lee Moffitt Cancer Center and Research Institute Inc	06/21/20	2D 3D TSV
US10358436	643	201	HGNC:11393 HGNC:11390 HGNC:3765	Kinase inhibitors and method of treating cancer	University Health Network	06/21/20	2D 3D TSV
US10357493	402	201	HGNC:4852 HGNC:14064	Metalloenzyme inhibitor compounds	Selenity Therapeutics (Bermuda), Ltd.	06/21/20	2D 3D TSV
US10336774	68	64	HGNC:9644	N-azaspirocycloalkane substituted N-heteroaryl compounds and compositions for inhibiting the activity of SHP2	Novartis AG	06/21/20	2D 3D TSV
US10336754	22	8	HGNC:6371 HGNC:3529	Pyrimidinones as factor XIa inhibitors	Bristol-Myers Squibb Co.	06/21/20	2D 3D TSV
US10336762	1932	935	HGNC:11892 HGNC:17967	Pyrrolo[1,2-b]pyridazine derivatives	Gilead Sciences Inc	06/21/20	2D 3D TSV
US10336759	26	26	HGNC:6190	Salts and processes of preparing a PI3K inhibitor	Incyte Corporation	06/21/20	2D 3D TSV
US10336731	14	14	HGNC:6059	Substituted 1H-indole-2-carboxamide compounds as indoleamine-2,3-dioxygenase inhibitors	Merck Sharp & Dohme Corp	06/21/20	2D 3D TSV
US10358416	288	286	HGNC:4501	Substituted pyrrolidines as G-protein coupled receptor 43 agonists	Epics Therapeutics	06/21/20	2D 3D TSV
US10336741	56	18	HGNC:3528 HGNC:3529 HGNC:3535	Substituted pyrrolidines as factor XIa inhibitors for the treatment thromboembolic diseases	Ono Pharmaceutical Co., Ltd	06/21/20	2D 3D TSV
US10336761	682	341	HGNC:11773	TGFβ receptor antagonist	Bristol-Myers Squibb Co.	06/21/20	2D 3D TSV
US10336752	15	11	HGNC:12440	TYK2 inhibitors, uses, and methods for production thereof	Nimbus Lakshmi, Inc.	06/21/20	2D 3D TSV
US10336757	25	25	HGNC:1735	Treatment of neurodegenerative diseases through inhibition of HSP90	Sloan-Kettering Institute for Cancer Research	06/21/20	2D 3D TSV
US10358435	116	66		Triazolyl pyrimidinone compounds as PDE2 inhibitors	Merck Sharp & Dohme Corp	06/21/20	2D 3D TSV
US10358449	5	5	HGNC:3009	Xanthine derivative	Jiangsu Tasly Diyi Pharmaceutical Co, LTD.	06/21/20	2D 3D TSV
US10351548	11	11	HGNC:8816	2-oxo-1,2-dihydropyridine-3-carboxamide compounds and their use as inhibitors of PDK1	International Society for Drug Development S.R.L.	06/12/20	2D 3D TSV
US10351563	236	233	HGNC:19679	Biaryl kinase inhibitors	Bristol-Myers Squibb Co.	06/12/20	2D 3D TSV
US10351575	161	158	HGNC:8031	Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain	Array BioPharma Inc	06/12/20	2D 3D TSV
US10351570	11	10	HGNC:6307	Compounds and uses thereof	Kala Pharmaceuticals, Inc.	06/12/20	2D 3D TSV
US10351558	215	212	HGNC:3551	Factor IXa inhibitors	Merck Sharp & Dohme Corp	06/12/20	2D 3D TSV
US10351547	267	263	HGNC:11331	Somatostatin modulators and uses thereof	CRINETICS PHARMACEUTICALS, INC.	06/12/20	2D 3D TSV
US10343992	273	268		1-cyano-pyrrolidine compounds as USP30 inhibitors	Missions Therapeutics Limited	06/09/20	2D 3D TSV
USRE47493	273	267	HGNC:3309	Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity	Boehringer Ingelheim International GmbH	06/09/20	2D 3D TSV
US10344000	39	35		Substituted bicyclic pyrazole compounds as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp	06/09/20	2D 3D TSV
US10344025	605	595		GLS1 inhibitors for treating disease	The University of Texas System	06/08/20	2D 3D TSV
US10344004	1	1		Inhibitor of the mutated isocitrate dehydrogenase IDH1 R132H	Bayer Pharma Aktiengesellschaft	06/08/20	2D 3D TSV
US10344034	19	13	HGNC:4421	Pyrazolopyrimidone or Pyrrolotriazone derivatives, method of preparing same, and pharmaceutical applications thereof	Shanghai Hengrui Pharmaceutical Co., Ltd	06/08/20	2D 3D TSV
US10342794	7	7	HGNC:11491	Substituted imidazo[1,2-a]pyrazines as Syk inhibitors	Gilead Sciences Inc	06/08/20	2D 3D TSV
US10016430	30	15	HGNC:7218 HGNC:12015	1-[2-(aminomethyl)benzyl]-2-thioxo-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-ones as inhibitors of myeloperoxidase	AstraZeneca AB	06/01/20	2D 3D TSV
USRE46942	106	38	HGNC:270 HGNC:11941 HGNC:272 HGNC:15677	4-piperidinyl compounds for use as tankyrase inhibitors	Novartis AG	06/01/20	2D 3D TSV
US10017516	326	67	HGNC:171 HGNC:1076 HGNC:172 HGNC:175	BMP inhibitors and methods of use thereof	The Brigham and Women's Hospital, Inc.	06/01/20	2D 3D TSV
US10017501	84	42		Benzimidazole derivatives as bromodomain inhibitors	Gilead Sciences Inc	06/01/20	2D 3D TSV
US10017502	22	18		Benzoxazinone amides as mineralocorticoid receptor modulators	AstraZeneca AB	06/01/20	2D 3D TSV
US10016438	200	37	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	06/01/20	2D 3D TSV
US10016439	11	11	HGNC:4079	Fused imidazole compounds	Ono Pharmaceutical Co., Ltd	06/01/20	2D 3D TSV
US10017504	140	68	HGNC:4849 HGNC:4848	Piperidine isoxazole and isothiazole orexin receptor antagonists	Merck Sharp & Dohme Corp	06/01/20	2D 3D TSV
US10016420	14	14	HGNC:3357	Substituted pyridazines for the treatment of pain	Inhibitaxin Limited	06/01/20	2D 3D TSV
US10017468	277	276	HGNC:4501	Substituted pyrrolidines as G-protein coupled receptor 43 agonists	Ogeda SA	06/01/20	2D 3D TSV
US10336710	12	12	HGNC:17989	Benzimidazole derivatives, preparation method therefor, and applications thereof	TBA	05/31/20	2D 3D TSV
US10336721	35	35	HGNC:7097	Biaryltriazole inhibitors of macrophage migration inhibitory factor	Yale University	05/31/20	2D 3D TSV
US10329302	370	361	HGNC:17967	Bicyclic-fused heteroaryl or aryl compounds	Pfizer Inc	05/31/20	2D 3D TSV
US10329291	53	27	HGNC:934 HGNC:933	C5-C6-carbocyclic fused iminothiadiazine dioxides as BACE inhibitors, compositions, and their use	TBA	05/31/20	2D 3D TSV
US10335399	59	59	HGNC:4594	Chromane, isochromane and dihydroisobenzofuran derivatives as mGluR2—negative allosteric modulators, compositions, and their use	TBA	05/31/20	2D 3D TSV
US10335392	43	41	HGNC:11892	Cyclic compounds useful as modulators of TNF α	Bristol-Myers Squibb Co.	05/31/20	2D 3D TSV
US10329286	11	11		FXR (NR1H4) modulating compounds	Gilead Sciences Inc	05/31/20	2D 3D TSV
US10329299	436	107	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Heterocyclic compounds and uses thereof	Infinity Pharmaceuticals Inc	05/31/20	2D 3D TSV
US10329307	74	70		Heterocyclic compounds as inhibitors of platelet aggregation	Universite de Montreal	05/31/20	2D 3D TSV
US10329303	52	52	HGNC:23357	Heterocyclic inhibitors of monocarboxylate transporter	The Scripps Research Institute	05/31/20	2D 3D TSV
US10336717	549	510	HGNC:933	Inhibitors of beta-secretase	Vitae Pharmaceuticals, LLC	05/31/20	2D 3D TSV
US10335409	178	86		Inhibitors of hepatitis C virus	Gilead Pharmasset LLC	05/31/20	2D 3D TSV
US10329320	66	61		Neuroactive steroids, compositions, and uses thereof	Sage Therapeutics, Inc.	05/31/20	2D 3D TSV
US10335401	95	94	HGNC:7045	Non-aromatic heterocyclic derivative having MGAT2 inhibitory activity	Shionogi & Co., Ltd	05/31/20	2D 3D TSV
US10336684	60	53	HGNC:19061	Phenyl-(aza)cycloalkyl carboxylic acid GPR120 modulators	Bristol=Myers Squibb Company	05/31/20	2D 3D TSV
US10329294	290	280	HGNC:17967	Pyrazolopyrimidine inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	05/31/20	2D 3D TSV
US10329295	163	162	HGNC:17967	Pyrrolotriazine inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	05/31/20	2D 3D TSV
US10329282	123	123		Rho-associated protein kinase inhibitor, pharmaceutical composition comprising the same, as well as preparation method and use thereof	Beijing Tide Pharmaceutical Co., Ltd	05/31/20	2D 3D TSV
US10335402	23	23		Sulfonyl piperidine derivatives and their use for treating prokineticin mediated gastrointestinal disorders	Takeda Pharmaceutical Co., Ltd	05/31/20	2D 3D TSV
USRE47451	45	9	HGNC:2730 HGNC:2731	Thieno[3,2-D]pyrimidine derivatives having inhibitory activity for protein kinases	Hanmi Pharm. Co., Ltd	05/31/20	2D 3D TSV
US10011588	308	149	HGNC:4849 HGNC:4848	1,2-substituted cyclopentanes as orexin receptor antagonists	Takeda Pharmaceutical Co., Ltd	05/26/20	2D 3D TSV
US10011627	18	9	HGNC:11037 HGNC:11036	C-aryl glucoside derivative, preparation methods thereof, and medical applications thereof	YOUNGENE THERAPEUTICS CO., LTD	05/26/20	2D 3D TSV
US10011599	101	99	HGNC:6840	Compounds and compositions as inhibitors of MEK	Novartis AG	05/26/20	2D 3D TSV
US10011568	40	21	HGNC:11526 HGNC:2637	Cyclohexyl pyridine derivative	Kissei Pharmaceutical Co., Ltd	05/26/20	2D 3D TSV
US10011595	242	120	HGNC:4849 HGNC:4848	Ethyldiamine orexin receptor antagonists	Merck Sharp & Dohme Corp	05/26/20	2D 3D TSV
US10011607	111	111	HGNC:4596	Ethynyl derivatives	Hoffman-La Roche Inc	05/26/20	2D 3D TSV
US10011593	16	13	HGNC:6307 HGNC:8804 HGNC:9437	Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitors	Allergan Inc	05/26/20	2D 3D TSV
US10011611	44	4	HGNC:4852 HGNC:14064 HGNC:19086 HGNC:14068 HGNC:13315 HGNC:4853 HGNC:18128	Histone deacetylase inhibitors and methods for use thereof	Reaction Biology Corp	05/26/20	2D 3D TSV
US10011604	60	60	HGNC:8031	Method of treatment using substituted imidazo[1,2b]pyridazine compounds	Array BioPharma Inc	05/26/20	2D 3D TSV
US10010547	147	147	HGNC:1925	Pharmaceutical compounds	Cascadian Therapeutics, Inc.	05/26/20	2D 3D TSV
US10011571	26	3	HGNC:6190 HGNC:3763 HGNC:6192 HGNC:1057 HGNC:6193 HGNC:6171 HGNC:11584 HGNC:12440 HGNC:3767	Preparation method for aromatic heterocyclic compound used as selective JAK3 and/or JAK1 kinase inhibitor and application of aromatic heterocyclic compound	SHENZHEN CHIPSCREEN BIOSCIENCES, LTD.	05/26/20	2D 3D TSV
US10010539	216	108	HGNC:4848	Pyrazole, triazole and tetrazole orexin receptor antagonists	Merck Sharp & Dohme Corp	05/26/20	2D 3D TSV
US10005769	79	78	HGNC:3092	2,3-dihydrobenzofuran-5YL compounds as DYRK kinase inhibitors	4SC AG	05/18/20	2D 3D TSV
US10005792	140	135	HGNC:10894	Aminoindane-, aminotetrahydronaphthalene- and aminobenzocyclobutane-derived PRMT5-inhibitors	CTXT PTY. LTD.	05/18/20	2D 3D TSV
US10005788	52	24	HGNC:7027 HGNC:12446	Bicyclic fused pyrimidine compounds as TAM inhibitors	Incyte Corporation	05/18/20	2D 3D TSV
US10005768	136	135	HGNC:10597	Carboxamide derivatives and use thereof	Purdue Pharma LP	05/18/20	2D 3D TSV
US10004738	49	48	HGNC:933	Combination treatment comprising administration of 2-amino-3,5,5-trifluoro-3,4,5,6-tetrahydropyridines	H. Lundbeck A/S	05/18/20	2D 3D TSV
US10005735	104	40	HGNC:2240 HGNC:16889	Inhibitors of RPN11	California Institute of Technology	05/18/20	2D 3D TSV
US10005783	105	105	HGNC:8031	Method of treatment using substituted pyrazolo[1,5-a] pyrimidine compounds	Array BioPharma Inc	05/18/20	2D 3D TSV
US10005762	159	80	HGNC:6656	Pyridine derivatives	Astellas Pharma Inc	05/18/20	2D 3D TSV
US10005756	77	76	HGNC:16672	Pyrrolidinone derivatives as MetAP-2 inhibitors	Merck Patent GmbH	05/18/20	2D 3D TSV
US10005739	214	213	HGNC:2730	Quinazolinone and isoquinolinone derivative	Chugai Seiyaku Kabushiki Kaisha	05/18/20	2D 3D TSV
US10005782	218	200	HGNC:1133	Substituted pyrazolo[1,5-a]pyrimidines as bruton's tyrosine kinase modulators	BeiGene, Ltd	05/18/20	2D 3D TSV
US10004755	149	40	HGNC:7027 HGNC:12446 HGNC:3765	Therapeutic uses of selected pyrrolopyrimidine compounds with anti-mer tyrosine kinase activity	University of North Carolina at Chapel Hill	05/18/20	2D 3D TSV
US10329256	159	43	HGNC:6833 HGNC:6834 HGNC:29079	(Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors	Oryzon Genomics, S.A.	05/11/20	2D 3D TSV
US10323042	246	64	HGNC:8781	6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide compounds	Pfizer Inc	05/11/20	2D 3D TSV
US10323060	37	34	HGNC:7967	Benzoic acid derivatives of bile acid as FXR/TGR5 agonists and methods of use thereof	Enanta Pharmaceuticals Inc	05/11/20	2D 3D TSV
US10000483	117	27	HGNC:1079 HGNC:1057 HGNC:1133 HGNC:6193 HGNC:11719 HGNC:7972 HGNC:3942	Bone marrow on X chromosome kinase (BMX) inhibitors and uses thereof	Dana-Farber Cancer Institute Inc	05/11/20	2D 3D TSV
US9999624	8	8	HGNC:933	Combination Alzheimer therapy using anti-N3pGlu Abeta antibodies + a BACE inhibitor	Eli Lilly and Company	05/11/20	2D 3D TSV
US10000507	426	142	HGNC:19310 HGNC:8987	Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors	Incyte Corporation	05/11/20	2D 3D TSV
US10000487	21	13	HGNC:7110 HGNC:7111	Heterocyclic compounds that inhibit the kinase activity of Mnk useful for treating various cancers	eFFECTOR Therapeutics Inc	05/11/20	2D 3D TSV
US10323032	332	111	HGNC:8537	P2X7 Modulators	Janssen Pharmaceutica NV	05/11/20	2D 3D TSV
US9999619	794	387		Piperidin-4-yl azetidine derivatives as JAK1 inhibitors	Incyte Holdings Corporation	05/11/20	2D 3D TSV
USRE47437	55	24	HGNC:1232 HGNC:12680 HGNC:14661	Prolyl hydroxylase inhibitors and methods of use	Akebia Therapeutics, Inc.	05/11/20	2D 3D TSV
US10000468	22	21	HGNC:4515	Pyrazines as modulators of GPR6	Takeda Pharmaceutical Co., Ltd	05/11/20	2D 3D TSV
US10323038	290	143		Pyrazole compounds and methods of making and using same	ABIDE THERAPEUTICS, INC.	05/11/20	2D 3D TSV
US10000476	229	150	HGNC:7160 HGNC:195 HGNC:7173 HGNC:7163 HGNC:7175 HGNC:7176 HGNC:7155 HGNC:7166 HGNC:7159	Pyridone derivative, pharmaceutical containing the same and methods of use thereof	Kaken Pharmaceutical Co., Ltd	05/11/20	2D 3D TSV
US10328074	61	61		Substituted [1,2,4]triazolo[4,3-a]pyrazines as BRD4 inhibitors	Boehringer Ingelheim International GmbH	05/11/20	2D 3D TSV
US10328054	69	69		Substituted pyrrolidines as mGluR5 antagonists	Hua Medicine (Shanghai) Ltd.	05/11/20	2D 3D TSV
US10328053	138	135	HGNC:10905	Substituted pyrrolizine compounds and uses thereof	Gilead Sciences Inc	05/11/20	2D 3D TSV
US10323036	218	217		TYK2 inhibitors and uses thereof	Nimbus Lakshmi, Inc.	05/11/20	2D 3D TSV
US10329273	24	22	HGNC:7045	Tetrazolone-substituted dihydropyridinone MGAT2 inhibitors	Bristol-Myers Squibb Co.	05/11/20	2D 3D TSV
US10328077	121	118	HGNC:29079	Treatment of relapsed and/or refractory solid tumors and non-hodgkin's lymphomas	Celgene Corporation	05/11/20	2D 3D TSV
US10000475	14	14	HGNC:10597	Triazine carboxamides as sodium channel blockers	Purdue Pharma LP	05/11/20	2D 3D TSV
US10329280	3	3	HGNC:6307	Urea derivatives and uses thereof	Kala Pharmaceuticals, Inc.	05/11/20	2D 3D TSV
US10322118	24	21	HGNC:3402	Compounds and methods for inhibiting Cif virulence factor	Dartmouth College	05/10/20	2D 3D TSV
US10323016	48	24	HGNC:19680	Imidazol- or 1,2,4-triazol-derivatives and their use	UNIVERSITE DE LILLE 2 DROIT ET SANTE	05/10/20	2D 3D TSV
US10323000	355	196	HGNC:5992 HGNC:8537	Indole derivatives and their use in neurodegenerative diseases	Merck Patent GmbH	05/10/20	2D 3D TSV
US10322143	63	61	HGNC:220 HGNC:221	Inhibitors of ADAMTS4 or ADAMTS5 for use in preventing or treating cardiac remodeling and chronic heart failure	UNIVERSITETET I OSLO	05/10/20	2D 3D TSV
US10322108	46	46		N-benzoate group substituted benzopyrroline-2-one derivative and use thereof	Beijing Hanmi Pharmaceutical Co., Ltd.	05/10/20	2D 3D TSV
US10322140	24	13	HGNC:2637 HGNC:3537	Preparation and use of 7a-heterocycle substituted-6,6-difluoro bicyclic himbacine derivatives as PAR-1 receptor antagonists	TBA	05/10/20	2D 3D TSV
US10323019	18	6	HGNC:6190 HGNC:6192 HGNC:6193	Pyrazolylaminobenzimidazole derivatives as JAK inhibitors	Eli Lilly and Company	05/10/20	2D 3D TSV
US10323022	648	638	HGNC:8031	Pyrrolidinyl urea, pyrrolidinyl thiourea and pyrrolidinyl guanidine compounds as TrkA kinase inhibitors	Array BioPharma Inc	05/10/20	2D 3D TSV
US10323018	229	227	HGNC:30092	Quinazoline and quinoline compounds and uses thereof	Millennium Pharmaceuticals Inc	05/10/20	2D 3D TSV
US10323023	19	19	HGNC:10252	Rho-associated protein kinase inhibitor, pharmaceutical composition comprising the same, as well as preparation method and use thereof	Beijing Tide Pharmaceutical Co., Ltd	05/10/20	2D 3D TSV
US10323029	995	365	HGNC:3169 HGNC:3167 HGNC:3165 HGNC:14299 HGNC:3170	Sphinogosine-1-phosphate receptor modulators for treatment of cardiopulmonary disorders	The Scripps Research Institute	05/10/20	2D 3D TSV
US10323020	15	13	HGNC:283	Substituted piperidinyl tetrahydroquinolines	Bayer Pharma Aktiengesellschaft	05/10/20	2D 3D TSV
US10323021	206	114	HGNC:6251	Triazoles as NR2B receptor inhibitors	JANSSEN PHARMACEUTICALS, INC.	05/10/20	2D 3D TSV
US9994571	22	11	HGNC:8154 HGNC:8156	10-substituted morphinan hydantoins	Purdue Pharma LP	05/07/20	2D 3D TSV
US9993478	104	32	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6874 HGNC:6876	1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl) oxy) napththalen-1-yl) ureas as P38 MAP knase inhibitors	Respivert Ltd	05/05/20	2D 3D TSV
US9993465	57	10		2,5-disubstituted-pyridyl nicotinic ligands, and methods of use thereof	Georgetown University	05/05/20	2D 3D TSV
US9994552	278	138	HGNC:6342	Compositions useful for treating disorders related to kit	BLUEPRINT MEDICINES CORPORATION	05/05/20	2D 3D TSV
US9994546	130	129	HGNC:29079	Cyclopropylamines as LSD1 inhibitors	Incyte Corporation	05/05/20	2D 3D TSV
US9994525	16	16		H3 antagonists containing phenoxypiperidine core structure	Richter Gedeon Nyrt.	05/05/20	2D 3D TSV
US9994547	150	149	HGNC:11584	Heteroarylamide inhibitors of TBK1	Takeda Pharmaceutical Co., Ltd	05/05/20	2D 3D TSV
US9994550	8	8	HGNC:3594	Heterocyclic modulators of lipid synthesis for use against cancer and viral infections	3-V Biosciences, Inc.	05/05/20	2D 3D TSV
US9994590	59	54	HGNC:8772	Substituted [1,2,4]triazolo[1,5-a]pyrazines as phosphodiesterase inhibitors	Sunovion Pharmaceuticals Inc	05/05/20	2D 3D TSV
US9994576	33	33	HGNC:1133	Substituted pyrazolo[3,4-d]pyrimidines as kinase inhibitors	Principia Biopharma Inc	05/05/20	2D 3D TSV
US9993479	43	43	HGNC:8031	Trk-inhibiting compound	Ono Pharmaceutical Co., Ltd	05/05/20	2D 3D TSV
US9988392	21	13	HGNC:8154 HGNC:8156	7-beta-alkyl analogs of orvinols	Purdue Pharma LP	04/30/20	2D 3D TSV
US9987274	135	47	HGNC:11526 HGNC:11527 HGNC:11528	N-acyl-(3-substituted)-(8-substituted)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists	Ogeda SA	04/30/20	2D 3D TSV
US9987255	48	24	HGNC:4849 HGNC:4848	5,5-bicyclic oxazole orexin receptor antagonists	Merck Sharp & Dohme Corp	04/25/20	2D 3D TSV
US9987253	8	8		Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes	Jenrin Discovery Inc	04/25/20	2D 3D TSV
US9988375	36	33		Inhibitors of lysine gingipain	CORTEXYME, INC.	04/25/20	2D 3D TSV
US9987259	31	31	HGNC:1960	Pharmaceutical composition comprising pyridone derivatives	SK Biopharmaceuticals Co. Ltd	04/25/20	2D 3D TSV
US9987278	41	41		Pharmaceutical composition for treating FLT3 mutation-positive cancer, mutant FLT3 inhibitor and uses thereof	FUJIFILM Corporation	04/25/20	2D 3D TSV
US9987252	5	5		Primary amines and derivitves thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto	Arena Pharmaceuticals Inc	04/25/20	2D 3D TSV
US9987276	467	239	HGNC:1079 HGNC:6193 HGNC:6171 HGNC:3236	Substituted 2,4-diaminopyrimidines as kinase inhibitors	Celgene CAR LLC	04/25/20	2D 3D TSV
US9981963	29	29	HGNC:1974	3-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-c]pyridine derivatives as NIK inhibitors	Janssen Pharmaceutica NV	04/18/20	2D 3D TSV
US9981944	245	124	HGNC:11773	GDF-8 inhibitors	Rigel Pharmaceuticals, Inc	04/18/20	2D 3D TSV
US9981901	75	73	HGNC:3449	IRE-1α inhibitors	FOSUN ORINOVE PHARMATECH, INC.	04/18/20	2D 3D TSV
US9981975	438	146	HGNC:7027 HGNC:12446	Pyrrolotriazine compounds as tam inhibitors	Incyte Corporation	04/18/20	2D 3D TSV
US9981909	592	296	HGNC:5301 HGNC:11050 HGNC:5295 HGNC:5294	Serotonin receptor modulators	Janssen Pharmaceutica NV	04/18/20	2D 3D TSV
US9981925	150	74	HGNC:391 HGNC:10436	Substituted benzo[d][1,2,3]triazines as p70S6K inhibitors	Merck Patent GmbH	04/18/20	2D 3D TSV
US9981950	116	116	HGNC:6251	Triazoles as NR2B receptor inhibitors	JANSSEN PHARMACEUTICALS, INC.	04/18/20	2D 3D TSV
US9981973	20	10	HGNC:11708 HGNC:6059	Tricyclic compounds as inhibitors of immunosuppression mediated by tryptophan metabolization	NewLink Genetics Corporation	04/18/20	2D 3D TSV
US9980929	73	73		Trifluoromethylpropanamide derivatives	Hoffman-La Roche Inc	04/18/20	2D 3D TSV
US10314832	18	17	HGNC:2514	β- and γ-diketones and γ-hydroxyketones as Wnt/β-catenin signaling pathway activators	Samumed, LLC	04/15/20	2D 3D TSV
US10308635	23	23		1-sulfonyl piperidine derivatives as modulators of prokineticin receptors	Takeda Pharmaceutical Co., Ltd	04/15/20	2D 3D TSV
US10308629	47	40	HGNC:1148	1H-pyrrol-3-amines	Bayer Pharma Aktiengesellschaft	04/15/20	2D 3D TSV
US10307427	23	18	HGNC:6857	Apoptosis signal-regulating kinase inhibitors	Gilead Sciences Inc	04/15/20	2D 3D TSV
US10308636	80	80	HGNC:2843	Aromatic heterocyclic compound	Mitsubishi Tanabe Pharma Corporation	04/15/20	2D 3D TSV
US10308660	171	170	HGNC:9644	Compounds and compositions for inhibiting the activity of SHP2	Novartis AG	04/15/20	2D 3D TSV
US10308607	3	3	HGNC:4006	Fucosidase inhibitors	HORIZON ORPHAN LLC	04/15/20	2D 3D TSV
US10308628	10	10	HGNC:338	Heterocyclic compounds and methods for their use	Novartis AG	04/15/20	2D 3D TSV
US10308644	271	267		Heterocyclic compounds as immunomodulators	Incyte Corporation	04/15/20	2D 3D TSV
US10308615	344	163		Heterocyclic compounds as inhibitors of Vanin-1 enzyme	Pfizer Inc	04/15/20	2D 3D TSV
US10308663	3	3	HGNC:9636	Inhibitors of PTP4A3 for the treatment of cancer	University of Virginia Patent Foundation	04/15/20	2D 3D TSV
US10308648	15	15	HGNC:1778	Inhibitors of cyclin-dependent kinase 7 (CDK7)	Syros Pharmaceuticals, Inc.	04/15/20	2D 3D TSV
US10314827	21	18	HGNC:441	Methods of use of cyclopamine analogs	Infinity Pharmaceuticals Inc	04/15/20	2D 3D TSV
US10308620	74	74	HGNC:1950	Muscarinic M1 receptor positive allosteric modulators	Suven Life Sciences Limited	04/15/20	2D 3D TSV
US10308667	168	167	HGNC:32311	Oxadiazolopyridine derivatives for use as ghrelin O-acyl transferase (GOAT) inhibitors	Boehringer Ingelheim International GmbH	04/15/20	2D 3D TSV
US10308645	86	43	HGNC:4849 HGNC:4848	Piperidine oxadiazole and thiadiazole orexin receptor antagonists	Merck Sharp & Dohme Corp	04/15/20	2D 3D TSV
US10308654	32	18	HGNC:1722	Preparation and use of kinase inhibitor	CHANGZHOU LONGTHERA PHARMACEUTICALS INC.	04/15/20	2D 3D TSV
US10308605	14	14		Proton pump inhibitors	Takeda Pharmaceutical Co., Ltd	04/15/20	2D 3D TSV
US10308659	246	121	HGNC:2160 HGNC:2159	Pyridine derivatives	Hoffmann-La Roche Inc	04/15/20	2D 3D TSV
US10307414	35	34	HGNC:1133	Pyridinyl and fused pyridinyl triazolone derivatives	Takeda Pharmaceutical Co., Ltd	04/15/20	2D 3D TSV
US10308634	22	22	HGNC:17967	Substituted indazoles, methods for the production thereof, pharmaceutical preparations that contain said new substituted indazoles, and use of said new substituted indazoles to produce drugs	Bayer Pharma Aktiengesellschaft	04/15/20	2D 3D TSV
US10307413	679	673		Tetrahydro- and dihydro-isoquinoline PRMT5 inhibitors and uses thereof	Epizyme Inc	04/15/20	2D 3D TSV
US10307426	36	16	HGNC:6190 HGNC:6192	Therapeutic compounds and compositions, and methods of use thereof	Genentech Inc	04/15/20	2D 3D TSV
US10308614	304	238		Therapeutic compounds and uses thereof	Genentech Inc	04/15/20	2D 3D TSV
US10308637	319	310	HGNC:6863	Therapeutic inhibitory compounds	LIFESCI PHARMACEUTICALS, INC.	04/15/20	2D 3D TSV
US10308662	114	28	HGNC:8979 HGNC:8978 HGNC:8980 HGNC:8977	Thienopyranones as kinase and epigenetic inhibitors	Signal Rx Pharmaceuticals Inc	04/15/20	2D 3D TSV
US10308652	64	60	HGNC:11892	Tricyclic heterocyclic compounds useful as inhibitors of TNF	Bristol-Myers Squibb Co.	04/15/20	2D 3D TSV
US9975876	63	31	HGNC:4849 HGNC:4848	2-pyridyloxy-3-ester-4-ether orexin receptor antagonists	Merck Sharp & Dohme Corp	04/10/20	2D 3D TSV
US9974785	36	36	HGNC:5301	Aromatic heterocyclic derivatives and pharmaceutical applications thereof	Sunshine Lake Pharma Co., Ltd	04/10/20	2D 3D TSV
US9975862	12	2	HGNC:3023 HGNC:5286	Arylpiperazine derivatives and methods of utilizing same	Reviva Pharmaceuticals Inc	04/10/20	2D 3D TSV
US9975858	10	10	HGNC:10597	Benzimidazole derivatives and use thereof	Purdue Pharma LP	04/10/20	2D 3D TSV
US9975854	3	3	HGNC:8154	Benzomorphan analogs and use thereof	Purdue Pharma LP	04/10/20	2D 3D TSV
US9975902	13	11	HGNC:9257	Compounds for the inhibition of cyclophilins and uses thereof	Merck Patent GmbH	04/10/20	2D 3D TSV
US9975861	11	4	HGNC:933 HGNC:4617	Dual inhibitor compounds for use in the treatment of neurodegenerative disorders and alzheimer''s disease	FONDAZIONE ISTITUTO ITAIANO DI TECNOLOGIA	04/10/20	2D 3D TSV
US9975874	86	44	HGNC:6371 HGNC:3529	Factor XIa inhibitors	Merck Sharp & Dohme Corp	04/10/20	2D 3D TSV
US9975882	212	63	HGNC:1079 HGNC:1133 HGNC:11719 HGNC:12434	Heteroaromatic compounds as BTK inhibitors	Boehringer Ingelheim International GmbH	04/10/20	2D 3D TSV
US9975907	123	80	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Pyrimidinones as PI3K inhibitors	Incyte Holdings Corporation	04/10/20	2D 3D TSV
US9969723	53	50	HGNC:4498	3-(4-(benzyloxy)phenyl)hex-4-ynoic acid derivative, method of preparing same and pharmaceutical composition for preventing and treating metabolic disease including same as effective ingredient	HYUNDAI PHARM CO., LTD	04/06/20	2D 3D TSV
US9969687	122	122	HGNC:1610	Compounds useful as CCR9 modulators	Norgine B.V.	04/06/20	2D 3D TSV
US9969724	53	53	HGNC:3551	Factor IXa inhibitors	Merck Sharp & Dohme Corp	04/06/20	2D 3D TSV
US9969749	169	166	HGNC:17967	Inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	04/06/20	2D 3D TSV
US9969726	724	190		Metabotropic glutamate receptor negative allosteric modulators (NAMS) and uses thereof	Sanford-Burnham Medical Research Institute	04/06/20	2D 3D TSV
US9969738	28	6	HGNC:11526 HGNC:11527 HGNC:11528	N-acyl-(3-substituted)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor-mediated disorders	Ogeda SA	04/06/20	2D 3D TSV
US9969700	8	8	HGNC:8535	P2X4 receptor antagonist	Nippon Chemiphar Co., Ltd	04/06/20	2D 3D TSV
US9968610	15	10	HGNC:6251 HGNC:2625	Pyrrolopyrimidine derivatives as NR2B NMDA receptor antagonists	Rugen Holdings (Cayman) Limited	04/06/20	2D 3D TSV
US9969686	9	9	HGNC:348	Synthesis of diindolylmethanes and indolo[3,2-b]carbazoles, compounds formed thereby, and pharmaceutical compositions containing them	Wisconsin Alumni Research Foundation	04/06/20	2D 3D TSV
US9969743	260	130	HGNC:3023 HGNC:3024	Urea and amide derivatives of aminoalkylpiperazines and use thereof	Southern Research Institute	04/06/20	2D 3D TSV
US9963460	3	1	HGNC:8153 HGNC:8154 HGNC:8156	Morphinan derivative	University of Tsukuba	03/30/20	2D 3D TSV
US9963444	117	117	HGNC:736	N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and their use thereof	Northeastern University	03/30/20	2D 3D TSV
US9963434	220	220		N-arylmethyl sulfonamide negative modulators of NR2A	Luc Therapeutics, Inc.	03/30/20	2D 3D TSV
US9963446	26	26		Oxepan-2-yl-pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use	Genentech Inc	03/30/20	2D 3D TSV
US9963456	40	40	HGNC:1373	Pyrrolopyrimidine compound or salt thereof and compositions containing the pyrrolopyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd	03/30/20	2D 3D TSV
US9962388	45	45	HGNC:15631	Pyrrolopyrimidine compounds used as TLR7 agonist	Chia Tai Tianqing Pharmaceutical Group Co., Ltd	03/30/20	2D 3D TSV
US9963443	13	13		Radiolabeled compounds	Takeda Pharmaceutical Co., Ltd	03/30/20	2D 3D TSV
US9963439	46	18	HGNC:2637 HGNC:20581 HGNC:2603 HGNC:2622 HGNC:2623	Specific inhibitors of cytochrome P450 26 retinoic acid hydroxylase	University of Washington Through its Center for Commercialization	03/30/20	2D 3D TSV
US9963453	45	43	HGNC:8157	Substituted pyrazino[1,2-a]indoles as sigma receptor activity modulators	LABORATORIOS DEL DR. ESTEVE S.A.	03/30/20	2D 3D TSV
US9962398	60	15	HGNC:1373 HGNC:1383 HGNC:1371 HGNC:1368	Sulfonamide compounds for inhibition of metastatic tumor growth	Welichem Biotech Inc.	03/30/20	2D 3D TSV
US9962362	18	12	HGNC:3521 HGNC:9642	Use of small molecule inhibitors targeting EYA tyrosine phosphatase	Children''s Hospital Medical Center	03/30/20	2D 3D TSV
US10301320	27	25	HGNC:5154	Compositions and methods of modulating 15-PGDH activity	University of Kentucky Research Foundation	03/26/20	2D 3D TSV
US10301305	252	63		Heteroaromatic derivatives and their use as pharmaceuticals	Mutabilis	03/26/20	2D 3D TSV
US10301323	183	61	HGNC:4852 HGNC:4854 HGNC:4853	Histone deacetylase inhibitors	BioMarin Pharmaceutical Inc	03/26/20	2D 3D TSV
US10301291	31	31	HGNC:6872	Imidazole derivative having JNK inhibitory activity and use thereof	SAMJIN PHARMACEUTICAL CO., LTD.	03/26/20	2D 3D TSV
US10301317	373	365	HGNC:6871	Inhibitors of ERK and methods of use	Kura Oncology Inc	03/26/20	2D 3D TSV
US10301288	61	15	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6876	Kinase inhibitors	Topivert Pharma Limited	03/26/20	2D 3D TSV
US10301336	33	33	HGNC:2771	Phosphonate compounds for treatment of complement mediated disorders	Achillion Pharmaceuticals Inc	03/26/20	2D 3D TSV
US10301286	79	33	HGNC:6932 HGNC:6929 HGNC:6931	Piperazine derivative	Astellas Pharma Inc	03/26/20	2D 3D TSV
US10301306	185	180	HGNC:10021	Substituted dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-ones as RIPK3 inhibitors	Bristol-Myers Squibb Co.	03/26/20	2D 3D TSV
US10301297	63	62	HGNC:1133	Substituted nicotinimide inhibitors of BTK and their preparation and use in the treatment of cancer, inflammation and autoimmune disease	Guangzhou Innocare Pharma Tech Co., Ltd.	03/26/20	2D 3D TSV
US10301284	141	139	HGNC:6371	Therapeutic inhibitory compounds	LIFESCI PHARMACEUTICALS, INC.	03/26/20	2D 3D TSV
US10301278	58	54	HGNC:9644	1-(triazin-3-yl/pyridazin-3-yl)-piper(-azine)idine derivatives and compositions therefor for inhibiting the activity of SHP2	Novartis AG	03/25/20	2D 3D TSV
US10300056	14	14	HGNC:9843	CGRP receptor antagonists	Heptares Therapeutics Limited	03/25/20	2D 3D TSV
US10301272	844	306		Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ]	Phenex Pharmaceuticals AG	03/25/20	2D 3D TSV
US10301280	257	153	HGNC:6342	Compounds and methods for kinase modulation, and indications therefor	Plexxikon Inc.	03/25/20	2D 3D TSV
US10300051	61	61	HGNC:29079	Cyclopropylamines as LSD1 inhibitors	Incyte Corporation	03/25/20	2D 3D TSV
US10301269	41	41	HGNC:3827	Imidazole derivatives as formyl peptide receptor modulators	Allergan Inc	03/25/20	2D 3D TSV
US10300066	119	118	HGNC:1133	Polyfluorinated compounds acting as bruton tyrosine kinase inhibitors	Zhejiang DTRM Biopharma Co. Ltd	03/25/20	2D 3D TSV
US10300067	53	53	HGNC:644	Tetrahydropyridopyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd	03/25/20	2D 3D TSV
US10301253	203	87	HGNC:29079	Therapeutic compounds and uses thereof	Genentech Inc	03/25/20	2D 3D TSV
US10300048	73	53	HGNC:3553	Thiazolidinones as cellular anandamide uptake inhibitors and their use in the treatment of psychiatric or neurological disorders and inflammation, in particular neuroinflammation	UNIVERSITAT BERN	03/25/20	2D 3D TSV
US10300060	43	43	HGNC:8031	Trk-inhibiting compound	Ono Pharmaceutical Co., Ltd	03/25/20	2D 3D TSV
US10300058	50	18	HGNC:3236	Tyrosine kinase inhibitor and uses thereof	Xuanzhu Pharma Co., Ltd	03/25/20	2D 3D TSV
US10300074	114	40	HGNC:13702	Use of inhibitor of apoptosis protein (IAP) antagonists in HIV therapy	Sanford Burnham Prebys Medical Discovery Institute	03/25/20	2D 3D TSV
US9957268	196	88		1H-pyrrolo[2,3,c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins	Incyte Corporation	03/23/20	2D 3D TSV
US9956214	208	103		5-aminopyrazole-4-carboxamide inhibitors of CDPK1 from T. gondii and C. parvum	University of Washington Through its Center for Commercialization	03/23/20	2D 3D TSV
US9957261	118	59		6-amino-5,6,7,8-tetrahydronaphthalen-2-yl or 3-aminochroman-7-yl derivatives	Hoffman-La Roche Inc	03/23/20	2D 3D TSV
US9957235	248	139		Benzimidazol-2-amines as mIDH1 inhibitors	Bayer Pharma Aktiengesellschaft	03/23/20	2D 3D TSV
US9957263	371	184	HGNC:13575	Bromodomain inhibitors	AbbVie Inc	03/23/20	2D 3D TSV
US9957276	44	44	HGNC:1771	CDK inhibitors	GI Therapeutics, Inc.	03/23/20	2D 3D TSV
US9956208	4	4	HGNC:1133	Compounds for the treatment of cancer and inflammatory diseases	TBA	03/23/20	2D 3D TSV
US9957264	938	423	HGNC:6190 HGNC:6192	Geminally substituted cyanoethylpyrazolo pyridones as Janus kinase inhibitors	Merck Sharp & Dohme Corp	03/23/20	2D 3D TSV
US9957265	226	75	HGNC:6190 HGNC:6192	N-(2-cyano heterocyclyl) pyrazolo pyridones as janus kinase inhibitors	Merck Sharp & Dohme Corp	03/23/20	2D 3D TSV
US9956192	42	21	HGNC:4852 HGNC:14064	Selective histone deactylase 6 inhibitors	H. Lee Moffitt Cancer Center and Research Institute Inc	03/23/20	2D 3D TSV
US9951056	63	61	HGNC:1133	Substituted nicotinamide inhibitors of BTK and their preparation and use in the treatment of cancer, inflammation and autoimmune disease	Beijing Innocare Pharma Tech Co., Ltd.	03/18/20	2D 3D TSV
US9951063	147	147	HGNC:4540	8-(piperazin-1-yl)-1,2,3,4-tetrahydro-isoquinoline derivatives	IDORSIA PHARMACEUTICALS Ltd	03/16/20	2D 3D TSV
US9951077	118	116	HGNC:1133	Aminopyridazinone compounds as protein kinase inhibitors	Jiangsu Hengrui Medicine Co., Ltd.	03/16/20	2D 3D TSV
US9951027	390	346		Benzimidazol-2-amines as MIDH1 inhibitors	Bayer Pharma Aktiengesellschaft	03/16/20	2D 3D TSV
US9951071	443	219	HGNC:6371 HGNC:3529	Dihydropyridone P1 as factor XIa inhibitors	Bristol-Myers Squibb Co.	03/16/20	2D 3D TSV
US9951026	13	13	HGNC:3357	Heterocyclic vinyl autotaxin inhibitor compounds	PharmAkea Inc	03/16/20	2D 3D TSV
US9951086	310	305	HGNC:17967	Indazolecarboxamides, processes for their preparation, pharmaceutical preparations comprising them and their use for producing medicaments	Bayer Pharma Aktiengesellschaft	03/16/20	2D 3D TSV
US9949975	25	25	HGNC:933	Inhibitors of beta-secretase	Vitae Pharmaceuticals Inc	03/16/20	2D 3D TSV
US9951048	488	236	HGNC:4617 HGNC:3091	Isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	03/16/20	2D 3D TSV
US9951014	113	35	HGNC:7872 HGNC:7873	Mammalian and bacterial nitric oxide synthase inhibitors	Northwestern University	03/16/20	2D 3D TSV
US9949951	29	28	HGNC:6059	Pyrrolidine-2, 5-dione derivatives, pharmaceutical compositions and methods for use as IDO1 inhibitors	iTeos Therapeutics	03/16/20	2D 3D TSV
US9951035	6	3	HGNC:7175 HGNC:7176	Selective matrix metalloproteinase inhibitors	University of Notre Dame du Lac	03/16/20	2D 3D TSV
US9951029	63	63	HGNC:3765	Styryl quinazoline derivatives as pharmaceutically active agents	Vichem Chemie Kutató	03/16/20	2D 3D TSV
US9951033	23	23		Tertiary amines for use in the treatment of cardiac disorders	UNIVERSITETET I OSLO	03/16/20	2D 3D TSV
US9944601	159	43	HGNC:6833 HGNC:6834 HGNC:29079	(Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors	Oryzon Genomics, S.A.	03/12/20	2D 3D TSV
US9944646	114	109	HGNC:8977	Bicyclic azaheterocyclobenzylamines as PI3K inhibitors	Incyte Holdings Corporation	03/12/20	2D 3D TSV
US9944606	9	5	HGNC:2160 HGNC:2159	Cannabinoid receptor modulators	Arena Pharmaceuticals Inc	03/12/20	2D 3D TSV
US9944643	8	8	HGNC:3529	Factor XIa inhibitors	Merck Sharp & Dohme Corp	03/12/20	2D 3D TSV
US9944647	138	138	HGNC:29079	Heterocyclic compounds as LSD1 inhibitors	Incyte Corporation	03/12/20	2D 3D TSV
US9944645	205	205	HGNC:7029	Imidazotriazines and imidazopyrimidines as kinase inhibitors	Incyte Corporation	03/12/20	2D 3D TSV
US9944618	940	167	HGNC:6251 HGNC:11050 HGNC:2637 HGNC:2625 HGNC:11048 HGNC:11049	Inhibiting neurotransmitter reuptake	Mayo Foundation	03/12/20	2D 3D TSV
US9943516	19	17	HGNC:17967	Inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	03/12/20	2D 3D TSV
USRE46792	103	103	HGNC:8783	Oxazole compound and pharmaceutical composition	Otsuka Pharmaceutical Co., Ltd	03/12/20	2D 3D TSV
US9944624	126	61	HGNC:17432 HGNC:1936	Substituted amino triazoles useful as human chitinase inhibitors	OncoArendi Therapeutics SA	03/12/20	2D 3D TSV
US10294221	63	57		1, 3, 4-thiadiazole compounds and their use in treating cancer	AstraZeneca AB	03/10/20	2D 3D TSV
US10294230	48	11	HGNC:4586 HGNC:6251 HGNC:2625	3,3-difluoropiperidine carbamate heterocyclic compounds as NR2B NMDA receptor antagonists	Rugen Holdings (Cayman) Limited	03/10/20	2D 3D TSV
US10294218	165	150	HGNC:1780	4,6-disubstituted aminopyrimidine derivatives have anti-HIV activity	VIROSTATICS SRL	03/10/20	2D 3D TSV
US10294227	332	21	HGNC:11283 HGNC:12841 HGNC:9617 HGNC:8803 HGNC:4840 HGNC:6735 HGNC:3697 HGNC:4037 HGNC:1057 HGNC:76 HGNC:6342 HGNC:3955 HGNC:3942 HGNC:9967 HGNC:6524	Compounds	UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH	03/10/20	2D 3D TSV
US10292975	2	2		Compounds as rearranged during transfection (RET) inhibitors	GlaxoSmithKline	03/10/20	2D 3D TSV
US10294217	35	27	HGNC:1950	Fluoroindole derivatives as muscarinic M1 receptor positive allosteric modulators	Suven Life Sciences Limited	03/10/20	2D 3D TSV
US10294229	444	398	HGNC:17967	Heteroaryl substituted aminopyridine compounds	Bristol-Myers Squibb Co.	03/10/20	2D 3D TSV
US10294212	277	273	HGNC:27269 HGNC:6059	Inhibitors of the kynurenine pathway	CURADEV PHARMA, PVT. LTD.	03/10/20	2D 3D TSV
US10292981	53	47	HGNC:6001	Oxazoline and isoxazoline derivatives as CRAC modulators	LUPIN LIMITED	03/10/20	2D 3D TSV
US10294259	6	3	HGNC:11037 HGNC:11036	Phenyl c-glucoside derivative containing deoxyglucose structure, preparation method and use thereof	Tianjin Institute of Pharmaceutical Research	03/10/20	2D 3D TSV
US10294214	80	80	HGNC:6932	Positive allosteric modulators of human melanocortin-4 receptor	Vanderbilt University	03/10/20	2D 3D TSV
US10294223	197	129	HGNC:3689 HGNC:3688	Quinolone derivatives as fibroblast growth factor receptor inhibitors	Principia Biopharma Inc	03/10/20	2D 3D TSV
US10294226	60	15	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Small molecule inhibitors of the JAK family of kinases	Janssen Pharmaceutica NV	03/10/20	2D 3D TSV
US10294246	271	135	HGNC:9542 HGNC:9545	Substituted boronic acids and boronate esters as immunoproteasome inhibitors	Merck Patent GmbH	03/10/20	2D 3D TSV
US10292985	72	36	HGNC:11773	TGF beta receptor antagonists	Bristol-Myers Squibb Co.	03/10/20	2D 3D TSV
US9938265	43	33		1,3,4-thiadiazole compounds and their use in treating cancer	AstraZeneca AB	03/02/20	2D 3D TSV
US9938276	164	81	HGNC:4849 HGNC:4848	6,5-bicyclic octahydropyrrolopyridine orexin receptor antagonists	Merck Sharp & Dohme Corp	03/02/20	2D 3D TSV
US9938268	34	34	HGNC:11393	C-ring modified tricyclic benzonaphthiridinone protein kinase inhibitors and use thereof	Merck Patent GmbH	03/02/20	2D 3D TSV
US9938222	129	116	HGNC:19061	Cyclopropanecarboxylic acid GPR120 modulators	Bristol-Myers Squibb Co.	03/02/20	2D 3D TSV
US9938267	694	668		Heterocyclic inhibitors of glutaminase	Calithera Biosciences Inc	03/02/20	2D 3D TSV
US9938272	109	34	HGNC:9475 HGNC:3528 HGNC:3535	Hydrazine compound as blood coagulation factor Xa inhibitor	North China Pharmaceutical Company., Ltd.	03/02/20	2D 3D TSV
US9938274	44	22	HGNC:6307 HGNC:7029	Naphthyridine compounds, medical combinations and use thereof	NANJING NATINEFY PHARMATECH CO., LTD.	03/02/20	2D 3D TSV
US9938257	57	25	HGNC:6190 HGNC:6192 HGNC:11393 HGNC:11390 HGNC:3765	Substituted heteroaryl compounds and methods of use	CALITOR SCIENCES, LLC	03/02/20	2D 3D TSV
US9938289	9	9		Therapeutic pyrazolyl thienopyridines	FBM THERAPEUTICS, LLC	03/02/20	2D 3D TSV
US9938290	52	13	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors	Karus Therapeutics Limited	03/02/20	2D 3D TSV
US10287286	262	260	HGNC:14660	Compounds	Takeda Pharmaceutical Co., Ltd	02/29/20	2D 3D TSV
US9931340	68	66	HGNC:2671	Pyridazinone compounds and their use as DAAO inhibitors	Takeda Pharmaceutical Co., Ltd	02/29/20	2D 3D TSV
US10285983	70	70		3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-B] pyridines and therapeutic uses thereof	Samumed, LLC	02/27/20	2D 3D TSV
US10285982	66	66		3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof	Samumed, LLC	02/27/20	2D 3D TSV
US10287274	43	43	HGNC:5302	5-hydroxytryptamine receptor 7 activity modulators and their method of use	TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	02/27/20	2D 3D TSV
US10287270	3	3	HGNC:550	Amino pyrimidine SSAO inhibitors	Eli Lilly and Company	02/27/20	2D 3D TSV
US10287301	719	698	HGNC:2771	Aryl, heteroaryl, and heterocyclic compounds for treatment of medical disorders	Achillion Pharmaceuticals Inc	02/27/20	2D 3D TSV
US10287293	45	22		Bicyclic heterocyclic compounds as PDE2 inhibitors	Merck Sharp & Dohme Corp	02/27/20	2D 3D TSV
US10287292	184	129	HGNC:23692	CXCR7 antagonists	ChemoCentryx, Inc.	02/27/20	2D 3D TSV
US10287258	37	37	HGNC:2528	Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides as dipeptidyl peptidase 1 inhibitors	AstraZeneca AB	02/27/20	2D 3D TSV
US10287278	40	14	HGNC:6026 HGNC:6027	Chemokine CXCR1 and CXCR2 receptor antagonist compounds, and use thereof in the treatment of chemokine-mediated pathologies	Galderma Research & Development	02/27/20	2D 3D TSV
US10285988	30	30	HGNC:15983	Compounds for treatment of fibrosis diseases	CUREGENIX, INC.	02/27/20	2D 3D TSV
US10287300	130	64	HGNC:28426	Heterocyclic derivatives as modulators of kinase activity	Merck Patent GmbH	02/27/20	2D 3D TSV
US10287268	8	4	HGNC:4840 HGNC:1133	Imidazolyl kinase inhibitors and uses thereof	Dana-Farber Cancer Institute Inc	02/27/20	2D 3D TSV
US10287279	42	39	HGNC:433	Inhibitors of human 12/15-lipoxygenase	THE CHILDREN'S HOSPITAL CORPORATION	02/27/20	2D 3D TSV
US10287267	951	304	HGNC:4617 HGNC:3091	Isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	02/27/20	2D 3D TSV
US10287250	110	35	HGNC:8156	Morphan and morphinan analogues, and methods of use	ALKERMES PHARMA IRELAND LIMITED	02/27/20	2D 3D TSV
US10285989	371	197		Pyrimidinone amide compounds as PDE2 inhibitors	Merck Sharp & Dohme Corp	02/27/20	2D 3D TSV
US10287272	149	126		Substituted indazole compounds as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp	02/27/20	2D 3D TSV
US10287305	266	261	HGNC:4849	Substituted piperidine compound and use thereof	Takeda Pharmaceutical Co., Ltd	02/27/20	2D 3D TSV
US10287253	52	51	HGNC:15631	Substituted pyrimidines containing acidic groups as TLR7 modulators	APROS THERAPEUTICS, INC.	02/27/20	2D 3D TSV
US10287295	605	303	HGNC:11773	TGF-β inhibitors	Rigel Pharmaceuticals, Inc	02/27/20	2D 3D TSV
US10280166	126	125		2-(1H-indazol-3-yl)-3H-imidazo[4,5-B]pyridine and therapeutic uses thereof	Samumed, LLC	02/24/20	2D 3D TSV
US9932329	28	14	HGNC:6171 HGNC:12434	Benzimidazole derivatives as RLK and ITK inhibitors	Principia Biopharma Inc	02/24/20	2D 3D TSV
US9932325	215	166		Compounds, compositions, and methods	Denali Therapeutics Inc.	02/24/20	2D 3D TSV
US9932332	2	2	HGNC:7967	FXR (NR1H4) modulating compounds	Gilead Sciences Inc	02/24/20	2D 3D TSV
US10280171	183	98	HGNC:3255	Heterocyclic inhibitors of PTPN11	The University of Texas System	02/24/20	2D 3D TSV
US10280184	71	69	HGNC:1133	Heterocyclic kinase inhibitors	AbbVie Inc	02/24/20	2D 3D TSV
US9932350	108	101	HGNC:17967	Inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	02/24/20	2D 3D TSV
US10280167	39	39		Purine derivatives for the treatment of viral infections	Janssen Ireland	02/24/20	2D 3D TSV
US9932327	10	5	HGNC:1780 HGNC:1771	Rohitukine analogs as cyclin-dependent kinase inhibitors and a process for the preparation thereof	The Council of Scientific & Industrial Research	02/24/20	2D 3D TSV
US9931338	7	7	HGNC:11491	Syk inhibitors	Gilead Sciences Inc	02/24/20	2D 3D TSV
US9932341	125	112	HGNC:8977	Use of pyrazolopyrimidine derivatives for the treatment of PI3K-delta related disorders	Incyte Corporation	02/24/20	2D 3D TSV
US10278968	15	15		Combination therapy with glutaminase inhibitors	Calithera Biosciences Inc	02/21/20	2D 3D TSV
US10278929	41	36	HGNC:12405	Identification of stabilizers of multimeric proteins	The Board of Trustees of the Leland Stanford Junior University	02/21/20	2D 3D TSV
US10280160	31	26	HGNC:1884	Phthalazinone compounds and methods for the treatment of cystic fibrosis	Flatley Discovery Lab LLC	02/21/20	2D 3D TSV
US10280164	16	16	HGNC:6863	Pyrazolopyridone compounds and uses thereof	Incyte Corporation	02/21/20	2D 3D TSV
US10280144	213	213		Pyridazine derivatives as RORc modulators	Genentech Inc	02/21/20	2D 3D TSV
US10280165	40	40		Pyridopyrimidinones and methods of use thereof	Genentech Inc	02/21/20	2D 3D TSV
US10280150	297	183		Quinolinone pyrimidines compositions as mutant-isocitrate dehydrogenase inhibitors	FORMA TM2, INC.	02/21/20	2D 3D TSV
US10280174	3	2	HGNC:1133 HGNC:3236	Salt of fused pyrimidine compound and crystal thereof	Taiho Pharmaceutical Co., Ltd	02/21/20	2D 3D TSV
US10278975	186	172	HGNC:6871	Serine/threonine kinase inhibitors	Genentech Inc	02/21/20	2D 3D TSV
US10280149	220	219	HGNC:13610	Therapeutic compounds and uses thereof	Genentech Inc	02/21/20	2D 3D TSV
US10278962	24	11	HGNC:11177 HGNC:11178	Tricyclic analogues, preparation method and uses thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	02/21/20	2D 3D TSV
US10273234	26	26	HGNC:3357	Compounds that are S1P modulating agents and/or ATX modulating agents	BIOGEN MA INC.	02/20/20	2D 3D TSV
US10273222	604	163	HGNC:22978 HGNC:9886 HGNC:17071 HGNC:18039 HGNC:13610	Histone demethylase inhibitors	CELGENE QUANTSCEL RESEARCH, INC.	02/20/20	2D 3D TSV
US10272074	477	475	HGNC:7978	Inhibitors of glucocorticoid receptor translocation	Sanford Burnham Prebys Medical Discovery Institute	02/20/20	2D 3D TSV
US10273211	24	5	HGNC:3763 HGNC:6307 HGNC:11390 HGNC:3767 HGNC:7029 HGNC:9967 HGNC:3765	Metabolites of N-{4-([6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide	Exelixis Inc	02/20/20	2D 3D TSV
US10272079	361	180	HGNC:11073	NHE3-binding compounds and methods for inhibiting phosphate transport	ARDELYX, INC.	02/20/20	2D 3D TSV
US10272095	87	83	HGNC:2874	NRF2 regulators	GlaxoSmithKline	02/20/20	2D 3D TSV
US10272077	14	14		Piperidinone carboxamide azaindane CGRP receptor antagonists	Merck Sharp & Dohme Corp	02/20/20	2D 3D TSV
US10272087	50	8	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Pteridines as FGFR inhibitors	Astex Therapeutics Ltd	02/20/20	2D 3D TSV
US10273225	22	21	HGNC:4515	Pyrazines as modulators of GPR6	Takeda Pharmaceutical Co., Ltd	02/20/20	2D 3D TSV
US10273223	391	389	HGNC:3527	Substituted 6,5-fused bicyclic heteroaryl compounds	Epizyme Inc	02/20/20	2D 3D TSV
US10273244	348	173	HGNC:3023 HGNC:3024	Substituted hexahydropyrrolo[3,4-b]pyrroles and hexahydrocyclopenta[c]pyrroles as dopamine receptor modulators	Indivior UK Limited	02/20/20	2D 3D TSV
US10273230	16	15	HGNC:19061	Substituted phenyl alkanoic acid compounds as GPR120 agonists and uses thereof	Piramal Enterprises Limited	02/20/20	2D 3D TSV
US10273214	78	39	HGNC:4588 HGNC:4587 HGNC:4586	Subunit selective NMDA receptor potentiators for the treatment of neurological conditions	Emory University	02/20/20	2D 3D TSV
US10273259	881	804		Tricyclic sulfones as RORγ modulators	Bristol-Myers Squibb Co.	02/20/20	2D 3D TSV
US9890168	32	15	HGNC:3236	2,4-disubstituted 7H-pyrrolo[2,3-d]pyrimidine derivative, preparation method and medicinal use thereof	Shanghai Haiyan Pharmaceutical Technology Co., Ltd.	02/16/20	2D 3D TSV
US9890171	200	130	HGNC:2592	Aldosterone synthase inhibitors	Boehringer Ingelheim International GmbH	02/16/20	2D 3D TSV
US9890124	46	23	HGNC:15631 HGNC:15632	Benzazepine sulfonamide compounds	Hoffmann-La Roche Inc	02/16/20	2D 3D TSV
US9890162	156	52	HGNC:19310 HGNC:8987	Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors	Incyte Corporation	02/16/20	2D 3D TSV
US9890156	152	37	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	02/16/20	2D 3D TSV
US9890160	3	3	HGNC:550	Compounds I	Proximagen Limited	02/16/20	2D 3D TSV
US9890166	638	168	HGNC:13575 HGNC:1103 HGNC:2348 HGNC:1104	Imidazopyrrolidine derivatives and their use in the treatment of disease	Novartis AG	02/16/20	2D 3D TSV
US9890185	468	169	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6876	Urea derivatives useful as kinase inhibitors	Respivert Limited	02/16/20	2D 3D TSV
US9926281	1937	451	HGNC:7160 HGNC:195 HGNC:7155 HGNC:7166 HGNC:7159 HGNC:221	5-[(piperazin-1-yl)-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS inhibitors for the treatment of osteoarthritis	Galapagos NV	02/10/20	2D 3D TSV
US9926301	28	13		Bipyrazole derivatives as JAK inhibitors	Incyte Corporation	02/10/20	2D 3D TSV
US9926306	34	33		Inhibition of MCL-1 and/or BFL-1/A1	Dana-Farber Cancer Institute Inc	02/10/20	2D 3D TSV
US9926330	55	53	HGNC:17967	Inhibitors of IRAK4 activity	Merck Sharp & Dohme Corp	02/10/20	2D 3D TSV
US9926299	34	34	HGNC:1133	Inhibitors of bruton's tyrosine kinase	Centaurus BioPharma Co., Ltd	02/10/20	2D 3D TSV
US9926282	826	401	HGNC:10251 HGNC:10252	Phthalazinones and isoquinolinones as rock inhibitors	Bristol-Myers Squibb Co.	02/10/20	2D 3D TSV
US9926318	58	53	HGNC:3357	Tetracyclic autotaxin inhibitors	PharmAkea Inc	02/10/20	2D 3D TSV
USRE47351	11	11		2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists	Gilead Sciences Inc	02/07/20	2D 3D TSV
US10266528	23	22	HGNC:1133	2-oxo-imidazopyridines as reversible BTK inhibitors and uses thereof	Merck Patent GmbH	02/07/20	2D 3D TSV
US10266537	116	27	HGNC:6613 HGNC:3763 HGNC:11724 HGNC:6735 HGNC:4037 HGNC:3386 HGNC:5960 HGNC:6859 HGNC:9829 HGNC:3689 HGNC:6873 HGNC:7027 HGNC:3767 HGNC:2730 HGNC:7029 HGNC:3688 HGNC:2731 HGNC:6192 HGNC:8031 HGNC:12841 HGNC:9617 HGNC:8803 HGNC:4840 HGNC:3430 HGNC:6307 HGNC:1079 HGNC:1057 HGNC:1133 HGNC:3395 HGNC:77 HGNC:1097 HGNC:76 HGNC:3393 HGNC:3955 HGNC:3236 HGNC:2444 HGNC:1974 HGNC:6524	3-acetylenyl-pyrazole-pyrimidine derivative, and preparation method therefor and uses thereof	St. Chuan University	02/07/20	2D 3D TSV
US10265310	158	71	HGNC:3827 HGNC:3826	6-membered cyclic amines or lactames substituted with urea and phenyl	GRÜNENTHAL GMBH	02/07/20	2D 3D TSV
US10266550	64	26	HGNC:11986 HGNC:11989	Bacterial topoisomerase I inhibitors with antibacterial activity	THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES	02/07/20	2D 3D TSV
US10259818	114	109	HGNC:8977	Bicyclic azaheterocyclobenzylamines as PI3K inhibitors	Incyte Corporation	02/07/20	2D 3D TSV
US10266560	65	64	HGNC:7967	Bile acid analogs as FXR/TGR5 agonists and methods of use thereof	Enanta Pharmaceuticals Inc	02/07/20	2D 3D TSV
US10259776	16	13	HGNC:4685	Branched 3-phenylpropionic acid derivatives and their use	Bayer Intellectual Property GmbH	02/07/20	2D 3D TSV
US10266513	190	134	HGNC:1133 HGNC:3236	Bruton's tyrosine kinase inhibitors	Pfizer Inc	02/07/20	2D 3D TSV
US10266491	200	168	HGNC:1133	Carbazole derivatives	Bristol-Myers Squibb Co.	02/07/20	2D 3D TSV
US10266496	160	118	HGNC:12805 HGNC:17989	Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereof	Sunshine Lake Pharma Co., Ltd	02/07/20	2D 3D TSV
US10259816	26	26	HGNC:427	Condensed-ring pyrimidylamino derivative, preparation method therefor, and intermediate, pharmaceutical composition and applications thereof	GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD.	02/07/20	2D 3D TSV
US10266542	19	18	HGNC:3527	EZH2 inhibitors	Mirati Therapeutics Inc	02/07/20	2D 3D TSV
US10266535	56	29	HGNC:1133 HGNC:3765	Inhibitor of FLT3 kinase and use thereof	HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCES	02/07/20	2D 3D TSV
US10259786	8	4	HGNC:3023	Psychotropic agents and uses thereof	LB PHARMACEUTICALS INC.	02/07/20	2D 3D TSV
US10266526	956	932	HGNC:20982	Substituted 1,2,3-triazoles as SMYD inhibitors for treating cancer	Epizyme Inc	02/07/20	2D 3D TSV
US10266548	211	187	HGNC:1148	Substituted benzylindazoles for use as Bub1 kinase inhibitors in the treatment of hyperproliferative diseases	Bayer Intellectual Property GmbH	02/07/20	2D 3D TSV
US10259811	517	258	HGNC:11584 HGNC:14552	Tank-binding kinase inhibitor compounds	Gilead Sciences Inc	02/07/20	2D 3D TSV
US10266515	202	144	HGNC:6371	Therapeutic inhibitory compounds	LIFESCI PHARMACEUTICALS, INC.	02/07/20	2D 3D TSV
US10265307	324	106	HGNC:19310 HGNC:8987	Thiazolecarboxamides and pyridinecarboxamide compounds useful as Pim kinase inhibitors	Incyte Corporation	02/07/20	2D 3D TSV
US10266493	71	70	HGNC:17989	Thioacetate compounds, compositions and methods of use	Ardea Biosciences, Inc.	02/07/20	2D 3D TSV
US10266549	345	343	HGNC:12558	ULK1 inhibitors and methods using same	Salk Institute	02/07/20	2D 3D TSV
US9918985	181	155		Compounds and their use as BACE inhibitors	AstraZeneca AB	02/04/20	2D 3D TSV
US9920047	375	109	HGNC:6833 HGNC:6834 HGNC:29079	Cyclopropanamine compound and use thereof	Takeda Pharmaceutical Co., Ltd	02/04/20	2D 3D TSV
US9920032	510	168	HGNC:19310 HGNC:8987	Heterocyclic compounds useful as pim kinase inhibitors	Incyte Corporation	02/04/20	2D 3D TSV
US9920031	261	218	HGNC:1133	Indole carboxamide compounds	Bristol-Myers Squibb Co.	02/04/20	2D 3D TSV
US9920038	62	30	HGNC:4849	Methyl oxazole orexin receptor antagonists	Merck Sharp & Dohme Corp	02/04/20	2D 3D TSV
US9920054	104	104		Methyl- and trifluoromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof	Pfizer Inc	02/04/20	2D 3D TSV
US9920053	130	35	HGNC:6251 HGNC:11050 HGNC:11048 HGNC:11049	N-(hetero)aryl-substituted heteroyclic derivatives useful for the treatment of diseases or conditions related to the central nervous system	CHRONOS THERAPEUTICS LIMITED	02/04/20	2D 3D TSV
US9920060	80	79	HGNC:3430	Pyrazolo[3,4-d]pyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd	02/04/20	2D 3D TSV
US9918974	2	2		Pyridone derivatives as rearranged during transfection (RET) kinase inhibitors	GlaxoSmithKline	02/04/20	2D 3D TSV
US9918969	16	14	HGNC:3529	Substituted oxopyridine derivatives and use thereof as factor XIa/plasma	Bayer Pharma Aktiengesellschaft	02/04/20	2D 3D TSV
US9918990	226	111	HGNC:13575 HGNC:1103	Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors	Incyte Corporation	02/04/20	2D 3D TSV
US9914735	391	78	HGNC:11491 HGNC:11390 HGNC:4617 HGNC:3765	Heteroaryl Syk inhibitors	Boehringer Ingelheim International GmbH	01/30/20	2D 3D TSV
US9914707	30	30	HGNC:6307	Naphthylamide compound, preparation method and use thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	01/30/20	2D 3D TSV
US9914731	293	156	HGNC:7029	Pyrazolo[1,5-a]pyridine derivatives and methods of their use	IGNYTA, INC.	01/30/20	2D 3D TSV
US9914736	114	113	HGNC:8031	TrKA kinase inhibitors, compositions and methods thereof	Merck Sharp & Dohme Corp	01/30/20	2D 3D TSV
US9914740	420	404	HGNC:10252	Tricyclic pyrido-carboxamide derivatives as rock inhibitors	Bristol-Myers Squibb Co.	01/30/20	2D 3D TSV
US9914721	22	11	HGNC:4849 HGNC:4848	Use of benzimidazole-proline derivatives	IDORSIA PHARMACEUTICALS Ltd	01/30/20	2D 3D TSV
US9908875	45	45	HGNC:6857	Apoptosis signal-regulating kinase inhibitors	Gilead Sciences Inc	01/27/20	2D 3D TSV
US9908845	68	65	HGNC:12680	Aryl ethers and uses thereof	PELOTON THERAPEUTICS, INC.	01/27/20	2D 3D TSV
US9908886	266	132	HGNC:7110 HGNC:7111	Bicyclic heterocyclic derivatives as MNK1 and MNK2 modulators and uses thereof	Agency for Science, Technology and Research	01/27/20	2D 3D TSV
US9908899	143	48	HGNC:4852 HGNC:4854 HGNC:4853	Histone deacetylase inhibitors	BioMarin Pharmaceutical Inc	01/27/20	2D 3D TSV
US9908865	511	154	HGNC:22978 HGNC:9886 HGNC:17071 HGNC:18039 HGNC:13610	Histone demethylase inhibitors	Celgene Quanticel Research Inc	01/27/20	2D 3D TSV
US9907800	460	198	HGNC:11393 HGNC:11390 HGNC:11397 HGNC:3765	Kinase inhibitors and method of treating cancer	University Health Network	01/27/20	2D 3D TSV
US9908872	19	8	HGNC:1133 HGNC:4195 HGNC:7972	Methods to treat lymphoplasmacytic lymphoma	Dana-Farber Cancer Institute Inc	01/27/20	2D 3D TSV
US9908897	306	84	HGNC:6251 HGNC:11050 HGNC:11048 HGNC:11049	Spirocyclic derivatives	CHRONOS THERAPEUTICS LIMITED	01/27/20	2D 3D TSV
US9908895	196	88	HGNC:6190 HGNC:6192	Tricyclic fused thiophene derivatives as JAK inhibitors	Incyte Corporation	01/27/20	2D 3D TSV
US10246444	134	32	HGNC:3432 HGNC:3430 HGNC:3236	1,2-dithiolane and dithiol compounds useful in treating mutant EGFR-mediated diseases and conditions	SABILA BIOSCIENCES LLC	01/21/20	2D 3D TSV
US10246442	135	135		4-Aminoquinazolin compounds as prolyl hydroxylase inhibitors	Janssen Pharmaceutica NV	01/21/20	2D 3D TSV
US10253018	41	41	HGNC:6857	Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals Inc	01/21/20	2D 3D TSV
US9896418	68	65	HGNC:12680	Aryl ethers and uses thereof	PELOTON THERAPEUTICS, INC.	01/21/20	2D 3D TSV
US9903855	20	5	HGNC:5960 HGNC:11584 HGNC:14552 HGNC:1974	Assays for screening for or identifying an agent or molecule that can block or inhibit AVB3 integrin from forming a complex with KRAS	The Regents of the University of California	01/21/20	2D 3D TSV
US9896444	175	101		Benzamide derivatives for inhibiting the activity of ABL1, ABL2 and BCR-ABL1	Novartis AG	01/21/20	2D 3D TSV
US10246453	1146	330	HGNC:10593 HGNC:10585 HGNC:10596	Benzenesulfonamide compounds and their use as therapeutic agents	Xenon Pharmaceuticals Inc	01/21/20	2D 3D TSV
US9902722	237	234	HGNC:19679	Biaryl kinase inhibitors	Bristol-Myers Squibb Co.	01/21/20	2D 3D TSV
US10251892	856	186	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	01/21/20	2D 3D TSV
US10246462	92	88	HGNC:1605	Chemokine receptor modulators and uses thereof	FLX BIO, INC.	01/21/20	2D 3D TSV
US9896458	251	243		Compounds, compositions and methods	Denali Therapeutics Inc.	01/21/20	2D 3D TSV
US10253017	22	9	HGNC:7856 HGNC:263 HGNC:264	Derivatives of 2-aminopyridine as adenosine A2B receptor antagonists and ligands of the melatonin MT3 receptors	Palobiofarma, S.L.	01/21/20	2D 3D TSV
US10246466	54	18	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:8031 HGNC:8032 HGNC:8033 HGNC:427	Diaryl macrocycles as modulators of protein kinases	TP Therapeutics, Inc.	01/21/20	2D 3D TSV
US9895376	116	57		Fused tricyclic compounds as Raf kinase inhibitors	BeiGene, Ltd	01/21/20	2D 3D TSV
US9896436	329	106	HGNC:29012 HGNC:13606 HGNC:17071 HGNC:18039 HGNC:20672 HGNC:13610	Histone demethylase inhibitors	Celgene Quanticel Research Inc	01/21/20	2D 3D TSV
US10246456	686	509	HGNC:17967	IRAK4 inhibiting agents	BIOGEN MA INC.	01/21/20	2D 3D TSV
US10253004	54	53	HGNC:4498	Indanylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof	Boehringer Ingelheim International GmbH	01/21/20	2D 3D TSV
US10246457	56	28	HGNC:1133	Indazole and azaindazole Btk inhibitors	Merck Sharp & Dohme Corp	01/21/20	2D 3D TSV
US10252984	51	51	HGNC:4545	Inhibiting G protein coupled receptor 6 kinase polypeptides	Mayo Foundation	01/21/20	2D 3D TSV
US9902719	31	31	HGNC:29079	Inhibitors of lysine specific demethylase-1	Celgene Quanticel Research Inc	01/21/20	2D 3D TSV
US9902741	68	46	HGNC:8031	Macrocyclic compounds as TRK kinase inhibitors	Array BioPharma Inc	01/21/20	2D 3D TSV
US10251893	230	227	HGNC:15983	N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as Wnt signaling modulators	Novartis AG	01/21/20	2D 3D TSV
US9896435	31	31	HGNC:8031	N-pyrrolidinyl,N′-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors	Array BioPharma Inc	01/21/20	2D 3D TSV
US9902709	13	13	HGNC:6307	Polysubstituted pyridine compound, preparation method, use and pharmaceutical composition	PEKING UNIVERSITY FOUNDER GROUP CO., LTD.	01/21/20	2D 3D TSV
US10253015	169	85		Pyridinyl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors	FORMA TM2, INC.	01/21/20	2D 3D TSV
US9902726	5	4	HGNC:8154 HGNC:8156	Pyridone-sulfone morphinan analogs as opioid receptor ligands	Purdue Pharma LP	01/21/20	2D 3D TSV
US9902714	35	7	HGNC:6307 HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Quinoxaline derivatives useful as FGFR kinase modulators	Astex Therapeutics Ltd	01/21/20	2D 3D TSV
US10246467	67	57		Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-p53 inhibitors	Boehringer Ingelheim International GmbH	01/21/20	2D 3D TSV
US9902710	169	168	HGNC:8772	Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (PDE 10A)	Exonhit Therapeutics, SA	01/21/20	2D 3D TSV
US9896452	703	365	HGNC:4849 HGNC:4848	Substituted prolines/piperidines as orexin receptor antagonists	EOLAS THERAPEUTICS, INC.	01/21/20	2D 3D TSV
US10251889	530	232	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:8031 HGNC:12440	Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors	Array BioPharm Inc.	01/21/20	2D 3D TSV
US10253019	1854	609	HGNC:6192 HGNC:11584 HGNC:14552	Tank-binding kinase inhibitor compounds	Gilead Sciences Inc	01/21/20	2D 3D TSV
US9896447	46	46	HGNC:8031	TrkA kinase inhibitors, compositions and methods thereof	Merck Sharp & Dohme Corp	01/21/20	2D 3D TSV
US10238658	120	32	HGNC:4840 HGNC:11491 HGNC:11283 HGNC:4617 HGNC:4616 HGNC:6874 HGNC:6876	1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl) oxy) napththalen-1-yl) ureas as p38 MAP kinase inhibitors	Respivert Limited	12/30/19	2D 3D TSV
US10239843	681	620	HGNC:8605 HGNC:270	2,4-dioxo-quinazoline-6-sulfonamide derivatives as inhibitors of PARG	Cancer Research Technology Limited	12/30/19	2D 3D TSV
US10246425	16	16	HGNC:10593	3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2-carboxamide compounds	Parion Sciences Inc	12/30/19	2D 3D TSV
US10246432	25	22	HGNC:4597	4-(3-cyanophenyl)-6-pyridinylpyrimidine mGlu5 modulators	Heptares Therapeutics Limited	12/30/19	2D 3D TSV
US10239883	665	132	HGNC:6735 HGNC:4037 HGNC:1133 HGNC:11283 HGNC:6524	4-imidazopyridazin-1-yl-benzamides as BTK inhibitors	Merck Sharp & Dohme B.V.	12/30/19	2D 3D TSV
US10239868	43	43	HGNC:5302	5-hydroxytryptamine receptor 7 activity modulators and their method of use	TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	12/30/19	2D 3D TSV
US10239840	22	22		Benzoazepine derivatives	ViiV HEALTHCARE UK LIMITED	12/30/19	2D 3D TSV
US10238638	48	48		Benzothiazole and benzothiophene compounds	Universite de Montreal	12/30/19	2D 3D TSV
US10245267	2564	1057	HGNC:9829	Biaryl amide compounds as kinase inhibitors	Novartis AG	12/30/19	2D 3D TSV
US10238743	98	49	HGNC:934 HGNC:933	C5-C6-fused tricyclic iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use	TBA	12/30/19	2D 3D TSV
US10239870	462	190	HGNC:3023	Dopamine D3 receptor antagonists	Indivior UK Limited	12/30/19	2D 3D TSV
US10239838	106	53	HGNC:4849 HGNC:4848	Heteroaryl orexin receptor antagonists	Merck Sharp & Dohme Corp	12/30/19	2D 3D TSV
US10246419	13	12	HGNC:7965	Liver X receptor (LXR) modulators	RALEXAR THERAPEUTICS, INC.	12/30/19	2D 3D TSV
US10238633	584	357	HGNC:2528 HGNC:2536	Methods for treating pulmonary emphysema using substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of Cathepsin C	Boehringer Ingelheim International GmbH	12/30/19	2D 3D TSV
US10239835	142	141		N-alkylaryl-5-oxyaryl-octahydro-cyclopenta[c]pyrrole negative allosteric modulators of NR2B	CADENT THERAPEUTICS, INC.	12/30/19	2D 3D TSV
US10239887	97	75	HGNC:1953	Positive allosteric modulators of the muscarinic acetylcholine receptor M4	Vanderbilt University	12/30/19	2D 3D TSV
US10239881	26	25	HGNC:10020	RIPK2 inhibitors and method of treating cancer with same	University Health Network	12/30/19	2D 3D TSV
US10239882	86	86		Substituted 5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine compounds as PDE2 inhibitors	Dart NeuroScience (Cayman) Ltd	12/30/19	2D 3D TSV
US10239869	405	243	HGNC:10593 HGNC:10597	Sulfonamide compounds as voltage-gated sodium channel modulators	LUPIN LIMITED	12/30/19	2D 3D TSV
US10239861	60	58	HGNC:8638	Therapeutic compounds and uses thereof	Genetech, Inc	12/30/19	2D 3D TSV
US10239876	170	169	HGNC:3020	Triaza-spirodecanones as DDR1 inhibitors	Hoffman-La Roche Inc	12/30/19	2D 3D TSV
US10246426	240	240	HGNC:1395	Triazole compounds as T-type calcium channel blockers	IDORSIA PHARMACEUTICALS Ltd	12/30/19	2D 3D TSV
US10245275	158	76		Triterpenoids with HIV maturation inhibitory activity	VIIV HEALTHCARE UK (NO. 4) LIMITED	12/30/19	2D 3D TSV
US10246429	755	248	HGNC:934 HGNC:2529 HGNC:933	Vinyl fluoride cyclopropyl fused thiazin-2-amine compounds as beta-secretase inhibitors and methods of use	Amgen Inc	12/30/19	2D 3D TSV
US10227299	295	287	HGNC:1148	3-amino-1,5,6,7-tetrahydro-4H-indol-4-ones	Bayer Pharma Aktiengesellschaft	12/27/19	2D 3D TSV
US10233156	57	57	HGNC:85	9-membered fused ring derivative	Shionogi & Co., Ltd	12/27/19	2D 3D TSV
US10233178	24	8	HGNC:6833 HGNC:6834 HGNC:29079	Arylcyclopropylamine based demethylase inhibitors of LSD1 and their medical use	Oryzon Genomics, S.A.	12/27/19	2D 3D TSV
US10226452	45	45	HGNC:735	Benzoxazolone derivatives as acid ceramidase inhibitors, and their use as medicaments	University of California	12/27/19	2D 3D TSV
US10233188	433	221	HGNC:1771	CDK2/4/6 inhibitors	Pfizer Inc	12/27/19	2D 3D TSV
US10227357	1107	650	HGNC:6342	Compounds and methods for kinase modulation, and indications therefor	Plexxikon Inc.	12/27/19	2D 3D TSV
US10231967	323	159	HGNC:620	Compounds and their use as BACE inhibitors	AstraZeneca AB	12/27/19	2D 3D TSV
US10227360	50	49	HGNC:19061	Compounds for use as GPR120 agonists	Piramal Enterprises Limited	12/27/19	2D 3D TSV
US10227329	268	130	HGNC:9967	Compounds useful for treating disorders related to RET	BLUEPRINT MEDICINES CORPORATION	12/27/19	2D 3D TSV
US10227314	13	13	HGNC:2501	Cystathionine-gamma-lyase (CSE) inhibitors	SOVA PHARMACEUTICALS, INC.	12/27/19	2D 3D TSV
US10227373	6	6		Enantiomers of the 1′,6′-isomer of neplanocin A	Auburn University	12/27/19	2D 3D TSV
US10227334	8	8	HGNC:3467	Estrogen receptor modulators and uses thereof	Genentech Inc	12/27/19	2D 3D TSV
US10233187	49	47	HGNC:7967	Fused bicyclic compounds for the treatment of disease	AKARNA THERAPEUTICS, LTD.	12/27/19	2D 3D TSV
US10233189	78	76	HGNC:9967	Fused pyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd	12/27/19	2D 3D TSV
US10227310	6	6	HGNC:32311	Ghrelin 0-acyl transferase inhibitors	Eli Lilly and Company	12/27/19	2D 3D TSV
US10227312	46	46	HGNC:12524	Glucosylceramide synthase inhibitors for the treatment of diseases	BioMarin Pharmaceutical Inc	12/27/19	2D 3D TSV
US10227342	400	99	HGNC:3236	Heteroaryl compounds for kinase inhibition	ARIAD Pharmaceuticals Inc	12/27/19	2D 3D TSV
US10226449	595	337	HGNC:3594	Heterocyclic modulators of lipid synthesis and combinations thereof	3-V Biosciences, Inc.	12/27/19	2D 3D TSV
US10231957	21	21	HGNC:17071	Histone demethylase inhibitors	Celgene Quanticel Research Inc	12/27/19	2D 3D TSV
US10233190	160	157	HGNC:6059	IDO inhibitors	NewLink Genetics Corporation	12/27/19	2D 3D TSV
US10227341	146	145	HGNC:1133	Inhibiting agents for bruton's tyrosine kinase	BIOGEN MA INC.	12/27/19	2D 3D TSV
US10227327	27	11		Inhibitors of metallo-beta-lactamase (MBL) comprising a zinc chelating moiety	Universitetet | Oslo	12/27/19	2D 3D TSV
US10227343	112	109	HGNC:4596	Isoquiniline and napthalene-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction	Vanderbilt University	12/27/19	2D 3D TSV
US10233152	161	158	HGNC:29079	LSD1 inhibitors	Mirati Therapeutics Inc	12/27/19	2D 3D TSV
US10227331	1137	369		Metallo-β-lactamase inhibitors	Merck Sharp & Dohme Corp	12/27/19	2D 3D TSV
US10231963	109	39	HGNC:8156	Methods for treating depressive symptoms	ALKERMES PHARMA IRELAND LIMITED	12/27/19	2D 3D TSV
US10227346	104	104		Methyl- and trifluoromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use therof	Pfizer Inc	12/27/19	2D 3D TSV
US10227350	167	129	HGNC:8980	Phosphatidylinositol 3-kinase inhibitors	Gilead Sciences Inc	12/27/19	2D 3D TSV
US10227336	32	16	HGNC:4849 HGNC:4848	Pyrazole orexin receptor antagonists	Merck Sharp & Dohme Corp	12/27/19	2D 3D TSV
US10227295	48	24	HGNC:4852 HGNC:14064	Selective histone deactylase 6 inhibitors	H. Lee Moffitt Cancer Center and Research Institute Inc	12/27/19	2D 3D TSV
US10226464	150	75	HGNC:7794	Small molecule NF-κB inhibitors	ImmuneTarget, Inc.	12/27/19	2D 3D TSV
US10233173	647	642		Substituted 1,2,3-triazoles as NR2B-selective NMDA modulators	Janssen Pharmaceutica NV	12/27/19	2D 3D TSV
US10227338	181	136	HGNC:10593 HGNC:10597	Substituted benzenesulfonamides as sodium channel blockers	Daewoong Pharmaceutical Co., Ltd.	12/27/19	2D 3D TSV
US10233160	150	75	HGNC:391 HGNC:10436	Substituted pyrido[3,4-d]pyrimidines and pyrido[4,3-d]pyrimidines as p70S6K inhibitors	Merck Patent GmbH	12/27/19	2D 3D TSV
US10233182	245	243	HGNC:3357	Substituted spirocyclic inhibitors of autotaxin	X-Rx, Inc.	12/27/19	2D 3D TSV
US10227332	8	4	HGNC:2160	T-type calcium channel modulator and uses thereof	UTI LIMITED PARTNERSHIP	12/27/19	2D 3D TSV
US10233177	25	25		TRPV1 vanilloid receptor antagonists with a bicyclic portion	TBA	12/27/19	2D 3D TSV
US10227340	27	26	HGNC:17967	Thiazolyl- or thiadiazolyl-substituted pyridyl compounds useful as kinase inhibitors	Bristol-Myers Squibb Co.	12/27/19	2D 3D TSV
US10227359	58	28	HGNC:13575	Tricyclic heterocycles as bet protein inhibitors	Incyte Corporation	12/27/19	2D 3D TSV
US9872852	297	292	HGNC:17635	Compounds useful as immunomodulators	Bristol-Myers Squibb Co.	12/19/19	2D 3D TSV
US9873693	331	307		Methods of treatment using pyridinonyl PDK1 inhibitors	Sunesis Pharmaceuticals Inc	12/19/19	2D 3D TSV
US9873683	43	43	HGNC:8535	P2X4 receptor antagonist	Nippon Chemiphar Co., Ltd	12/19/19	2D 3D TSV
US9873709	1144	774	HGNC:6190 HGNC:6192	Triazolopyridine compounds, compositions and methods of use thereof	Genentech Inc	12/19/19	2D 3D TSV
US9867826	100	47	HGNC:391	Heterocycles as modulators of kinase activity	Merck Patent GmbH	12/12/19	2D 3D TSV
US9868726	123	72	HGNC:6307 HGNC:8804 HGNC:9437	Pyridyl benzothiophenes as kinase inhibitors	Allergan Inc	12/12/19	2D 3D TSV
US9868720	93	92	HGNC:6851	C-linked heterocycloaklyl substituted pyrimidines and their uses	Genentech Inc	12/10/19	2D 3D TSV
US9868738	102	51	HGNC:934 HGNC:933	Diazine-fused amidines as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp	12/10/19	2D 3D TSV
US9868744	23	19	HGNC:3020	Heteroaromatic compounds and their use as dopamine D1 ligands	Pfizer Inc	12/10/19	2D 3D TSV
US9868729	216	214	HGNC:11491	Inhibitors of protein kinases	Portola Pharmaceuticals Inc	12/10/19	2D 3D TSV
US9867833	197	185	HGNC:6871	Serine/threonine kinase inhibitors	Genentech Inc	12/10/19	2D 3D TSV
US9868748	113	110		Thiazolopyrrolidine inhibitors of ROR- γ	Vitae Pharmaceuticals Inc	12/10/19	2D 3D TSV
US9862688	47	7	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:76 HGNC:12440	Hydrophobically tagged janus kinase inhibitors and uses thereof	Dana-Farber Cancer Institute Inc	12/03/19	2D 3D TSV
US9862730	405	393	HGNC:3540	Imidazothiadiazole derivatives as protease activated receptor 4 (PAR4) inhibitors for treating platelet aggregation	Bristol-Myers Squibb Co.	12/03/19	2D 3D TSV
US9861612	9	7		Indolyl-containing RORγt inhibitors	ORCA PHARMACEUTICALS LIMITED	12/03/19	2D 3D TSV
US9862726	40	20	HGNC:8154 HGNC:8156	Opioid receptor modulating oxabicyclo[2.2.2]octane morphinans	Purdue Pharma LP	12/03/19	2D 3D TSV
US9862679	189	58		Potent and selective inhibitors of monoamine transporters; method of making; and use thereof	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH	12/03/19	2D 3D TSV
US9862711	91	13	HGNC:8978 HGNC:8984 HGNC:8975 HGNC:3942 HGNC:8974 HGNC:8977 HGNC:8976	Pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors	Novartis AG	12/03/19	2D 3D TSV
US9862721	13	13	HGNC:3357	Tetrahydrocarboline derivative	Ono Pharmaceutical Co., Ltd	12/03/19	2D 3D TSV
US9862707	103	83	HGNC:8031	TrkA kinase inhibitors, compositions and methods thereof	Merck Sharp & Dohme Corp	12/03/19	2D 3D TSV
US9856252	107	106	HGNC:10894	2-(hetero)aryl-benzimidazole and imidazopyridine derivatives as inhibitors of asparagime emethyl transferase	Cancer Therapeutics CRC Pty Ltd	11/21/19	2D 3D TSV
US9855269	345	340	HGNC:6866	Aminoquinazoline and pyridopyrimidine derivatives	Genentech Inc	11/21/19	2D 3D TSV
US9856239	42	38	HGNC:17989	Carboxylic acid compound, method for preparation thereof, and use thereof	InventisBio Shanghai Ltd.	11/21/19	2D 3D TSV
US9856263	41	39	HGNC:3020	Heteroaromatic compounds and their use as dopamine D1 ligands	Pfizer Inc	11/21/19	2D 3D TSV
US9856220	125	124	HGNC:8772	Inhibitor compounds of phosphodiesterase type 10A	AbbVie Deutschland GmbH & Co. KG	11/21/19	2D 3D TSV
US9856257	68	68	HGNC:16672	Pyrazolonaphthyridinone derivatives as MetAP2 inhibitors (methionine aminopeptidase type-2)	Sanofi	11/21/19	2D 3D TSV
US9856274	42	42	HGNC:8772	Substituted pyrazolo[1,5-a]pyridines as PDE-10 inhibitors	Sunovion Pharmaceuticals Inc	11/21/19	2D 3D TSV
US9856250	58	57	HGNC:1395	Substituted tropane derivatives	Toa Eiyo Ltd	11/21/19	2D 3D TSV
US9855229	11	11		Treatment of respiratory disorders using ROR-gamma inhibitors	GLENMARK PHARMACEUTICALS S.A.	11/21/19	2D 3D TSV
US9849138	10	5		1,4-benzodiazepone-2,5-diones and related compounds with therapeutic properties	The Regents of the University of Michigan	11/14/19	2D 3D TSV
US9850203	128	122	HGNC:3357	Autotaxin inhibitor compounds	PharmAkea Inc	11/14/19	2D 3D TSV
US9850225	378	375	HGNC:17635	Compounds useful as immunomodulators	Bristol-Myers Squibb Co.	11/14/19	2D 3D TSV
US9845313	167	151	HGNC:10597	Cycloalkane derivatives	Daiichi Sankyo Company, Limited	11/14/19	2D 3D TSV
US9850245	24	21	HGNC:6255	Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp	11/14/19	2D 3D TSV
US9845310	772	485	HGNC:339	Intermediates for preparing triazole agonists of the APJ receptor	Amgen Inc	11/14/19	2D 3D TSV
US9845308	66	62		Isoindoline inhibitors of ROR-gamma	Vitae Pharmaceuticals Inc	11/14/19	2D 3D TSV
US9844553	19	10	HGNC:2592 HGNC:2591	Pyrazolopyridyl compounds as aldosterone synthase inhibitors	Merck Sharp & Dohme Corp	11/14/19	2D 3D TSV
US9844535	28	27	HGNC:6080	SHP2 inhibitors and methods of treating autoimmune and/or glomerulonephritis-associated diseases using SHP2 inhibitors	Indiana University Research and Technology Corporation	11/14/19	2D 3D TSV
US9845333	164	47	HGNC:4848	Substituted 2-azabicycles and their use as orexin receptor modulators	TBA	11/14/19	2D 3D TSV
US9850258	152	43	HGNC:6192 HGNC:1133	Substituted tetrahydrocarbazole and carbazole carboxamide compounds	Bristol-Myers Squibb Co.	11/14/19	2D 3D TSV
US9850277	402	207		Therapeutically active compositions and their methods of use	Agios Pharmaceuticals Inc	11/14/19	2D 3D TSV
US9850257	26	13		Tricyclic heterocycles as BET protein inhibitors	Incyte Corporation	11/14/19	2D 3D TSV
US9840503	33	10	HGNC:7027 HGNC:12446	Heterocyclic compounds and uses thereof	Incyte Corporation	10/31/19	2D 3D TSV
US9840501	242	121		Morpholin-pyridine derivatives	Hoffmann-La Roche Inc	10/31/19	2D 3D TSV
US9840508	90	18	HGNC:11526 HGNC:11527 HGNC:11528	N-acyl-(3-substituted)-(8-methyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a] pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor-mediated disorders	OGED SA	10/31/19	2D 3D TSV
US9840498	95	32	HGNC:8978 HGNC:8975 HGNC:8977	Substituted quinazolin-4-one derivatives	Novartis AG	10/31/19	2D 3D TSV
US9834554	41	41	HGNC:1133	BTK inhibitors	Merck Sharp & Dohme Corp	10/28/19	2D 3D TSV
US9834513	249	125	HGNC:6371 HGNC:6357	Benzylamine derivatives	Kalvista Pharmceuticals Limited	10/28/19	2D 3D TSV
US9834543	16	12	HGNC:10597	Indazoles and use thereof	Purdue Pharma LP	10/28/19	2D 3D TSV
US9833448	14	14	HGNC:16709	Piperidinone carboxamide azaindane CGRP receptor antagonists	Merck Sharp & Dohme Corp	10/28/19	2D 3D TSV
US9834548	407	129	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyridazine compounds as JAK inhibitors	Portola Pharmaceuticals Inc	10/28/19	2D 3D TSV
US9834551	220	109	HGNC:6193 HGNC:6171	Substituted pyrrolo[2,3-b]pyrazines and substituted pyrazolo[3,4-b]pyridines as ITK and JAK kinase inhibitors	ARRIEN PHARMACEUTICALS LLC	10/28/19	2D 3D TSV
US9834564	209	209	HGNC:8772	Substituted quinolines as PDE-10 inhibitors	Sunovion Pharmaceuticals Inc	10/28/19	2D 3D TSV
US9833457	26	13	HGNC:8783	Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors	vTv Therapeutics LLC	10/28/19	2D 3D TSV
US9834565	58	29		Tricyclic heterocycles as bet protein inhibitors	Incyte Corporation	10/28/19	2D 3D TSV
US10221182	98	19	HGNC:4586 HGNC:6251 HGNC:2625	3,3-difluoro-piperidine derivatives as NR2B NMDA receptor antagonists	Rugen Holdings (Cayman) Limited	10/27/19	2D 3D TSV
US10221172	65	64	HGNC:4596	Benzothiazole and benzisothiazole-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction	Vanderbilt University	10/27/19	2D 3D TSV
US10221173	451	159	HGNC:6251 HGNC:3467	Chemical compounds	AstraZeneca AB	10/27/19	2D 3D TSV
US10221177	261	248	HGNC:497	Inhibiting the transient receptor potential A1 ion channel	Hydra Biosciences Inc	10/27/19	2D 3D TSV
US10221163	1497	492		Metallo-beta-lactamase inhibitors	Merck Sharp & Dohme Corp	10/27/19	2D 3D TSV
US10221174	46	22	HGNC:6943 HGNC:990	N-(phenylsulfonyl)benzamides and related compounds as BCL-2 inhibitors	The Regents of the University of Michigan	10/27/19	2D 3D TSV
US10221197	528	147	HGNC:8978 HGNC:8980 HGNC:8977	Phosphatidylinositol 3-kinase inhibitors	Gilead Sciences Inc	10/27/19	2D 3D TSV
US10221178	83	82	HGNC:8977	Purine inhibitors of human phosphatidylinositol 3-kinase delta	Merck Sharp & Dohme Corp	10/27/19	2D 3D TSV
US10221195	46	44	HGNC:438	Pyridine compounds	Daiichi Sankyo Company, Limited	10/27/19	2D 3D TSV
USRE47267	31	25	HGNC:6027	Pyridinecarboxamides as CXCR2 modulators	Syntrix Biosystems, Inc.	10/27/19	2D 3D TSV
US10221175	42	42	HGNC:1950	Substituted pyrrolo[3,4-e]indolizines, imidazo[1,2-a]pyrrolo[3,4-e]pyridines, pyrrolo[3,4-e][1,2,4]triazolo[1,5-a]pyridines and pyrrolo[3,4-e][1,2,4]triazolo[4,3-a]pyridines as positive allosteric modulators of muscarinic acetylcholine receptor M1	Vanderbilt University	10/27/19	2D 3D TSV
US9828368	146	64	HGNC:4849	Oxazole orexin receptor antagonists	Merck Sharp & Dohme Corp	10/24/19	2D 3D TSV
US9828396	92	92	HGNC:2771	Alkyne compounds for treatment of complement mediated disorders	Achillion Pharmaceuticals Inc	10/22/19	2D 3D TSV
US9828348	10	10	HGNC:10597	Benzimidazole derivatives and use thereof	Purdue Pharma LP	10/22/19	2D 3D TSV
US9828339	224	224	HGNC:1952	Biphenyl derivatives and methods for preparing same	DONG-A ST CO., LTD	10/22/19	2D 3D TSV
US9828343	199	93	HGNC:9886 HGNC:17071 HGNC:18039	Histone demethylase inhibitors	Celgene Quanticel Research Inc	10/22/19	2D 3D TSV
US9828369	167	166	HGNC:16940	Isoquinoline derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2	Merck Sharpe & Dohme Corp.	10/22/19	2D 3D TSV
US9828378	257	69	HGNC:8978 HGNC:8972 HGNC:8975 HGNC:8977	Kinase inhibitors and methods of use	Intellikine LLC	10/22/19	2D 3D TSV
US9828374	94	47		Substituted pyrazino[2,2-a]isoquinoline derivatives	Hoffmann-La Roche Inc	10/22/19	2D 3D TSV
US9828381	88	88		Substituted pyrazolopyrimidines and method of use	AbbVie Deutschland GmbH & Co. KG	10/22/19	2D 3D TSV