Search by Patent Identification

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Patent: (prefix with "US" like US6078908)

Patent	Data	Compounds	HGNC (for human-derived proteins)	Patent Title	Organization	Deposition	Downloads
US20200361871A1	233	229	HGNC:21625	COMPOUNDS	TBA	01/13/22	2D 3D TSV
US11124497	463	179		Inhibitors of cysteine proteases and methods of use thereof	Pardes Biosciences, Inc.	01/13/22	2D 3D TSV
US11072585	122	117	HGNC:6666	Fluorinated lysyl oxidase-like 2 inhibitors and uses thereof	PHARMAKEA, INC.	01/09/22	2D 3D TSV
US11071729	29	29	HGNC:4594	1′,3′-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2H,1′H-[1,4′]bipyridinyl-2′-ones	Addex Pharmaceuticals S.A.; Janssen Pharmaceuticals, Inc.	01/07/22	2D 3D TSV
US11071788	26	21	HGNC:6388	Antibody drug conjugates of kinesin spindel protein (KSP) inhibitors with antiB7H3-antibodies	BAYER PHARMA AKTIENGESELLSCHAFT	01/07/22	2D 3D TSV
US11071721	107	101		Bicyclic amide compounds and methods of use thereof	Genentech, Inc.	01/07/22	2D 3D TSV
US11072617	225	223		Bicyclic sulfones and sulfoxides and methods of use thereof	Genentech, Inc.	01/07/22	2D 3D TSV
US11072611	367	215	HGNC:3357	Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders	GALAPAGOS NV	01/07/22	2D 3D TSV
US11072607	46	41		Inhibitors of RIP1 kinase and methods of use thereof	Genentech, Inc.	01/07/22	2D 3D TSV
US11072619	39	13	HGNC:6190 HGNC:6192 HGNC:6193	Pyrazole[1,5-a] pyrimidine derivatives as kinase JAK inhibitors	Celon Pharma S.A.	01/07/22	2D 3D TSV
US11072626	31	31	HGNC:6563	Small molecule inhibitors of Galectin-3	Bristol-Myers Squibb Company	01/07/22	2D 3D TSV
US11071730	205	201	HGNC:6863	Substituted 6-azabenzimidazole compounds	Gilead Sciences, Inc.	01/07/22	2D 3D TSV
US11072582	277	275	HGNC:4501	Substituted pyrrolidines as G-protein coupled receptor 43 agonists	Epics Therapeutics	01/07/22	2D 3D TSV
US11046714	161	146	HGNC:263	2,2-difluorodioxolo A2A receptor antagonists	Merck Sharp & Dohme Corp.	12/28/21	2D 3D TSV
US11046713	40	19	HGNC:644	Androgen receptor modulating compounds	ORION CORPORATION	12/28/21	2D 3D TSV
US11046725	52	26	HGNC:6561 HGNC:6563	Galactoside inhibitor of galectins	GALECTO BIOTECH AB	12/28/21	2D 3D TSV
US11046712	181	175	HGNC:7056	Glycosidase inhibitors	Asceneuron SA	12/28/21	2D 3D TSV
US11046702	199	198	HGNC:4597	Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same	SK BIOPHARMACEUTICALS CO., LTD.	12/28/21	2D 3D TSV
US11046710	48	48	HGNC:438	Sulfonamide compounds	Daiichi Sankyo Company, Limited; Sanford Burnham Prebys Medical Discovery Institute	12/28/21	2D 3D TSV
US11046662	48	45	HGNC:12716 HGNC:497 HGNC:18083 HGNC:17961	2-aryl-4-hydroxy-1,3-thiazole derivatives useful as TRPM8-inhibitors in treatment of neuralgia, pain, COPD and asthma	DOMPÉ FARMACEUTICI S.P.A.	12/27/21	2D 3D TSV
US11046691	749	729		2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors	IDEAYA BIOSCIENCES, INC.	12/27/21	2D 3D TSV
US11046646	10	5	HGNC:3167 HGNC:3165	Alkylphenyl compounds	Bristol-Myers Squibb Company	12/27/21	2D 3D TSV
US11046658	260	127	HGNC:8978 HGNC:8977	Aminopyrazine derivatives as PI3K-γ inhibitors	Incyte Corporation	12/27/21	2D 3D TSV
US11045455	135	26	HGNC:6190 HGNC:2596 HGNC:6192 HGNC:6193 HGNC:6251 HGNC:2637 HGNC:2625 HGNC:12440	Azetidine derivative, preparation method therefor, and use thereof	SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.	12/27/21	2D 3D TSV
US11046649	149	148	HGNC:6059	Compounds useful as inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan dioxygenase	Board of Regents, The University of Texas System	12/27/21	2D 3D TSV
US11046671	26	12	HGNC:15631 HGNC:15632	Dihydropyrimidinyl benzazepine carboxamide compounds	Hoffmann-La Roche Inc.	12/27/21	2D 3D TSV
US11046682	39	39		Fused heterocyclic derivatives, their preparation methods thereof and medical uses thereof	Beijing Innocare Pharma Tech Co., Ltd	12/27/21	2D 3D TSV
US11046696	520	198	HGNC:9967	Fused pyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd.	12/27/21	2D 3D TSV
US11046680	486	436	HGNC:339	Heteroaryl-substituted triazoles as APJ receptor agonists	AMGEN INC.	12/27/21	2D 3D TSV
US11046652	39	36		Hydroxamic acids comprising pyrazole moiety and uses thereof	HAWAII BIOTECH, INC.	12/27/21	2D 3D TSV
US11046672	414	70	HGNC:8803 HGNC:3763 HGNC:6307 HGNC:8804 HGNC:3690 HGNC:3688	Indolinones compounds and their use in the treatment of fibrotic diseases	RespiVert Limited	12/27/21	2D 3D TSV
US11046688	205	202	HGNC:12401	Inhibitor compounds	Cancer Research Technology Limited	12/27/21	2D 3D TSV
US11046651	75	35	HGNC:3023 HGNC:5295 HGNC:5182	Piperazine substituted azapine derivatives and uses thereof	ALAIRION, INC.	12/27/21	2D 3D TSV
US11046670	63	27	HGNC:8157	Piperazinyl norbenzomorphan compounds and methods for using the same	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM	12/27/21	2D 3D TSV
US11045448	41	41	HGNC:7010	Piperidines as covalent menin inhibitors	THE REGENTS OF THE UNIVERSITY OF MICHIGAN	12/27/21	2D 3D TSV
US11045457	445	208	HGNC:11330 HGNC:11333	Piperidinyl-3-(aryloxy)propanamides and propanoates	Takeda Pharmaceutical Company Limited	12/27/21	2D 3D TSV
US11046689	289	159	HGNC:6251 HGNC:3467	Selective estrogen receptor down-regulators	AstraZeneca AB	12/27/21	2D 3D TSV
US11046675	8	8		Substituted isoquionline derivatives as immunomudulators	Bristol-Myers Squibb Company	12/27/21	2D 3D TSV
US11046681	33	33	HGNC:12630	Substituted piperidines for the treatment of cancer	LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD	12/27/21	2D 3D TSV
US11046698	1366	1145		TYK2 inhibitors and uses thereof	Nimbus Lakshmi, Inc.	12/27/21	2D 3D TSV
US11046686	30	30	HGNC:17967	Thiadiazole IRAK4 compounds	Gilead Sciences, Inc.	12/27/21	2D 3D TSV
US11066365	273	271		1-cyano-pyrrolidine compounds as USP30 inhibitors	Mission Therapeutics Limited	12/23/21	2D 3D TSV
US11066414	981	964	HGNC:3236	Cot modulators and methods of use thereof	Gilead Sciences, Inc.	12/23/21	2D 3D TSV
US11066413	60	57	HGNC:263	Aminopyrimidine five-membered heterocyclic compound, and intermediate, preparation method, pharmaceutical composition and application thereof	GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD.	12/20/21	2D 3D TSV
US11066409	217	211	HGNC:8537	Bicyclic nitrogen-containing heterocyclic derivatives and pharmaceutical composition comprising the same	SHIONOGI & CO., LTD.	12/20/21	2D 3D TSV
US11066404	6	6	HGNC:1771	Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors	Incyte Corporation	12/20/21	2D 3D TSV
US11066406	60	15		Small molecule inhibitors of the JAK family of kinases	Janssen Pharmaceutica NV	12/20/21	2D 3D TSV
US11066396	1453	478	HGNC:4852 HGNC:14064 HGNC:14068 HGNC:13315	3-aryl- heteroaryl substituted 5-trifluoromethyl oxadiazoles as histonedeacetylase 6 (HDAC6) inhibitors	MERCK SHARP & DOHME CORP.	12/19/21	2D 3D TSV
US11065253	471	329	HGNC:9413	Arylquinazolines	MERCK PATENT GMBH	12/19/21	2D 3D TSV
US11065231	55	55	HGNC:17967	Compounds and methods for the targeted degradation of interleukin-1 receptor- associated kinase 4 polypeptides	ARVINAS OPERATIONS, INC.	12/19/21	2D 3D TSV
US11065249	32	26	HGNC:16940	Diacylglycerol acyl transferase 2 inhibitor	Pfizer Inc.	12/19/21	2D 3D TSV
US11066360	104	102	HGNC:6371	Human plasma kallikrein inhibitors	BioCryst Pharmaceuticals, Inc.	12/19/21	2D 3D TSV
US11066363	22	13	HGNC:11305 HGNC:11306	Substituted 6,11-dihydro-5H-benzo[B]carbazoles as inhibitors of ALK and SRPK	DANA-FARBER CANCER INSTITUTE, INC.	12/19/21	2D 3D TSV
US11040966	1982	987	HGNC:4849 HGNC:4848	Benzimidazole-proline derivatives	IDORSIA PHARMACEUTICALS LTD	12/14/21	2D 3D TSV
US11040034	272	135	HGNC:2592 HGNC:2591	Metalloenzyme inhibitor compounds	PHASEBIO PHARMACEUTICALS, INC.	12/14/21	2D 3D TSV
US11041859	70	10	HGNC:17927 HGNC:30402 HGNC:23116	Methods of identifying SENP1 inhibitors	CITY OF HOPE	12/14/21	2D 3D TSV
US11040968	17	17	HGNC:6857	Pyridine derivative as ASK1 inhibitor and preparation method and use thereof	TBA	12/14/21	2D 3D TSV
US11040984	22	11	HGNC:3236	Quinazoline compound for EGFR inhibition	MEDSHINE DISCOVERY INC.	12/14/21	2D 3D TSV
US11040980	33	32	HGNC:1133	Substituted pyrazolo[3,4-d]pyrimidines as kinase inhibitors	Principia Biopharma Inc.	12/14/21	2D 3D TSV
US11040979	20	4	HGNC:6342	Substituted pyrrolo[1,2-b]pyridazines for treating disorders related to KIT and PDGFR	Blueprint Medicines Corporation	12/14/21	2D 3D TSV
US11040967	15	11	HGNC:12440	TYK2 inhibitors, uses, and methods for production thereof	Nimbus Lakshmi, Inc.	12/14/21	2D 3D TSV
US11040970	54	42	HGNC:10935	VMAT2 inhibitor compounds and compositions thereof	Neurocrine Biosciences, Inc.	12/14/21	2D 3D TSV
US11034715	248	146	HGNC:8021	Ectonucleotidase inhibitors and methods of use thereof	Calithera Biosciences, Inc.	12/06/21	2D 3D TSV
US11034717	33	11		Farnesoid X receptor modulators	Intercept Pharmaceuticals, Inc.	12/06/21	2D 3D TSV
US11034991	6	5	HGNC:29079	Methods to determine KDM1A target engagement and chemoprobes useful therefor	Oryzon Genomics S.A.	12/06/21	2D 3D TSV
US11034671	100	99	HGNC:6857	Apoptosis signal-regulating kinase inhibitors and uses thereof	SICHUAN HAISCO PHARMACEUTICAL CO., LTD.	12/05/21	2D 3D TSV
US11033547	127	100	HGNC:9644	Carboxamide-pyrimidine derivatives as SHP2 antagonists	Merck Patent GmbH	12/05/21	2D 3D TSV
US11033539	1210	551	HGNC:1954 HGNC:1953 HGNC:1950 HGNC:1952 HGNC:1951	Compounds of formulas (VII), (VIII), (IX), (XI), (XII), (XIII), and (XIV) as muscarinic receptor 4(M4) antagonists for treating neurological diseases	Neurocrine Biosciences, Inc.	12/05/21	2D 3D TSV
US11034678	17	16	HGNC:16940	Diacylglycerol acyl transferase 2 inhibitors	Pfizer Inc.	12/05/21	2D 3D TSV
US11034699	17	17	HGNC:4596	Ethynyl derivatives	Hoffmann-La Roche Inc.	12/05/21	2D 3D TSV
US11034705	52	52		Fused tricyclic ring derivatives as Src homology-2 phosphate inhibitors	Nikang Therapeutics, Inc.	12/05/21	2D 3D TSV
US11034692	420	390	HGNC:6863	Naphthyridines as inhibitors of HPK1	Genentech, Inc.	12/05/21	2D 3D TSV
US11034670	70	53	HGNC:270 HGNC:272	Poly-ADP ribose polymerase (PARP) inhibitors	Mitobridge, Inc.	12/05/21	2D 3D TSV
US11034698	115	94		Pyrazolo[ 1,5a]pyrimidine derivatives as IRAK4 modulators	Genentech, Inc.	12/05/21	2D 3D TSV
US11034658	65	65		Pyridinyl pyrazoles as modulators of RORγT	Janssen Pharmaceutica NV	12/05/21	2D 3D TSV
US11034691	995	366	HGNC:3169 HGNC:3167 HGNC:3165 HGNC:14299 HGNC:3170	Sphinogosine-1 -phosphate receptor modulators for treatment of cardiopulmonary disorders	THE SCRIPPS RESEARCH INSTITUTE	12/05/21	2D 3D TSV
US11034661	67	67	HGNC:6059	Substituted N′-hydroxycarbamimidoyl-1,2,5-oxadiazole compounds as indoleamine 2,3-dioxygenase IDO inhibitors	Merck Sharp & Dohme Corp.	12/05/21	2D 3D TSV
US11034694	837	825	HGNC:6863	Substituted isoindolin-1-ones and 2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-1-ones as HPK1 antagonists	Nimbus Saturn, Inc.	12/05/21	2D 3D TSV
US11028054	35	35	HGNC:2867	1, 4, 6-trisubstituted-2-alkyl-1H-benzo[d]imidazole derivatives as dihydroorotate oxygenase inhibitors	Merck Patent GmbH	11/29/21	2D 3D TSV
US11021493	720	166	HGNC:934 HGNC:2529 HGNC:933	1,4-thiazine dioxide and 1,2,4-thiadiazine dioxide derivatives as beta-secretase inhibitors and methods of use	Amgen Inc.	11/29/21	2D 3D TSV
US11026923	606	192	HGNC:8775 HGNC:8774 HGNC:8776	1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors	H. Lundbeck A/S	11/29/21	2D 3D TSV
US11028101	3	3	HGNC:10894	3-oxa-8-azabicyclo[3.2.1]octane derivatives and their use in the treatment of cancer and hemoglobinopathies	CTXT PTY LTD	11/29/21	2D 3D TSV
US11028093	867	205	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	4,6-substituted-pyrazolo[1,5-a]pyrazines as janus kinase inhibitors	ARRAY BIOPHARMA INC.; CELGENE CORPORATION	11/29/21	2D 3D TSV
US11021475	37	35		Amide-substituted heterocyclic compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses	Bristol-Myers Squibb Company	11/29/21	2D 3D TSV
US11021511	20	6		Cyclic dinucleotides as sting agonists	Janssen Biotech, Inc.	11/29/21	2D 3D TSV
US11028083	163	145	HGNC:23393 HGNC:18241	Ethanediamine-heterocycle derivatives as inhibitors of protein arginine methyltransferases	Board of Regents, The University of Texas System	11/29/21	2D 3D TSV
US11026937	134	134	HGNC:18368	Heteroaryl inhibitors of PAD4	Padlock Therapeutics, Inc.	11/29/21	2D 3D TSV
US11028067	15	7	HGNC:12437 HGNC:4623	Heteroarylsulfonyl-substituted pyridines and their use in the treatment of cancer	Oblique Therapeutics AB	11/29/21	2D 3D TSV
US11028058	12	12	HGNC:263	Heterocyclic compounds as adenosine antagonists	NUVATION BIO INC.	11/29/21	2D 3D TSV
US11021478	24	23	HGNC:1232	Indolizine derivatives and their application in medicine	KIND PHARMACEUTICAL	11/29/21	2D 3D TSV
US11028066	97	97	HGNC:29079	Inhibitors of lysine specific demethylase-1	Celgene Quanticel Research, Inc.	11/29/21	2D 3D TSV
US11021467	405	131	HGNC:8978 HGNC:8980 HGNC:8977	Phosphatidylinositol 3-kinase inhibitors	Gilead Sciences, Inc.	11/29/21	2D 3D TSV
US11026936	57	34	HGNC:8810	Piperidinyl-propanone derivatives	Merck Patent GmbH	11/29/21	2D 3D TSV
US11028041	36	18	HGNC:5253	Second generation GRP94-selective inhibitors	University of Kansas	11/29/21	2D 3D TSV
US11026958	41	36	HGNC:1960	Substituted 6-membered aryl or heteroaryl allosteric modulators of nicotinic acetylcholine receptors	Merck Sharp & Dohme Corp.	11/29/21	2D 3D TSV
US11021481	837	812	HGNC:6863	Substituted isoindolin-1-ones and 2,3-dihydro-1h-pyrrolo[3,4-c]pyridin-1-ones as HPK1 antagonists	Nimbus Saturn, Inc.	11/29/21	2D 3D TSV
US11028085	837	823	HGNC:6863	Substituted isoindolin-1-ones and 2,3-dihydro-1h-pyrrolo[3,4-c]pyridin-1-ones as hpk1 antagonists	Nimbus Saturn, Inc.	11/29/21	2D 3D TSV
US11028092	124	60	HGNC:8795	Substituted pyrazolo[3,4-d]pyrimidines as PDE9 inhibitors	Merck Sharp & Dohme Corp.	11/29/21	2D 3D TSV
US11028080	44	36		Substituted pyrimidines as LRKK2 inhibitors	DENALI THERAPEUTICS INC.	11/29/21	2D 3D TSV
US11028051	14	7		Tetrahydroquinoline-based bromodomain inhibitors	St. Jude Children''s Research Hospital	11/29/21	2D 3D TSV
US11028075	182	90	HGNC:10597	Therapeutic compounds and methods of use thereof	Genentech, Inc.	11/29/21	2D 3D TSV
US11021463	202	145	HGNC:6371	Therapeutic inhibitory compounds	ATTUNE PHARMACEUTICALS, INC.	11/29/21	2D 3D TSV
US11021515	404	207		Therapeutically active compounds and their methods of use	Agios Pharmaceuticals, Inc.	11/29/21	2D 3D TSV
US11028064	146	76	HGNC:6307	Tricyclic heterocyclic derivatives and uses thereof	AUCKLAND UNISERVICES LIMITED	11/29/21	2D 3D TSV
US11028104	83	42	HGNC:12008 HGNC:20692	Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same	MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN; FORSCHUNGSVERBUND BERLIN E.V.	11/29/21	2D 3D TSV
US11028090	505	491	HGNC:13575	[1,2,4]Triazolo[4,3-a]quinoxaline derivative, method for preparing same, and pharmaceutical composition for preventing or treating BET protein-related diseases, containing same as active ingredient	Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology	11/29/21	2D 3D TSV
US11020398	376	299	HGNC:1133	Amino-pyrrolopyrimidinone compounds and methods of use thereof	ArQule, Inc.	11/28/21	2D 3D TSV
US11020381	174	169	HGNC:10597	Biaryloxy derivatives as TTX-S blockers	RaQualia Pharma Inc.; XuanZhu Pharma Co., Ltd.	11/28/21	2D 3D TSV
US11021457	150	150		Class of isoindolone-imide ring-1,3-dione-2-ene compounds, composition and use thereof	WIGEN BIOMEDICINE TECHNOLOGY (SHANGHAI) CO., LTD.	11/28/21	2D 3D TSV
US11020397	70	44	HGNC:12805 HGNC:17989	Compounds and their use for reducing uric acid levels	Acquist LLC	11/28/21	2D 3D TSV
US11020395	154	115	HGNC:339	Cycloalkyl substituted triazole compounds as agonists of the APJ receptor	AMGEN INC.	11/28/21	2D 3D TSV
US11020380	410	396	HGNC:2348	Therapeutic compounds	CELGENE QUANTICEL RESEARCH, INC.	11/28/21	2D 3D TSV
US11021454	44	27	HGNC:12805	Type of aryl benzofuran amidated derivative and medical use thereof	CHINA PHARMACEUTICAL UNIVERSITY	11/28/21	2D 3D TSV
US11014905	114	36	HGNC:3023 HGNC:5286	2,6-disubstituted pyridine derivative	SUMITOMO DAINIPPON PHARMA CO., LTD.	11/22/21	2D 3D TSV
US11014923	152	37	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	11/22/21	2D 3D TSV
US11014911	1035	569	HGNC:1780 HGNC:1771 HGNC:4617 HGNC:1777 HGNC:1722 HGNC:1773	CDK2 inhibitors	Pfizer Inc.	11/22/21	2D 3D TSV
US11014912	68	68		Cyanopyrrolidine derivatives with activity as inhibitors of USP30	MISSION THERAPEUTICS LIMITED	11/22/21	2D 3D TSV
US11014920	36	35	HGNC:3530	Factor XIIa inhibitors	Merck Sharp & Dohme Corp.	11/22/21	2D 3D TSV
US11014930	78	78	HGNC:9967	Fused pyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd.	11/22/21	2D 3D TSV
US11014909	81	72	HGNC:3020	Heteroaromatic compounds and their use as dopamine D1 ligands	Pfizer Inc.	11/22/21	2D 3D TSV
US11013718	9	9	HGNC:29079	LSD1 inhibitors and medical uses thereof	Constellation Pharmaceuticals, Inc.	11/22/21	2D 3D TSV
US11014929	126	126	HGNC:6863	Pyrazolopyrimidine compounds and uses thereof	Incyte Corporation	11/22/21	2D 3D TSV
US11014913	855	800		Pyridazinones as PARP7 inhibitors	Ribon Therapeutics, Inc.	11/22/21	2D 3D TSV
US11014926	35	30	HGNC:7110 HGNC:7111	Pyrrolo-, pyrazolo-, imidazo-pyrimidine and pyridine compounds that inhibit MNK1 and MNK2	eFFECTOR Therapeutics, Inc.	11/22/21	2D 3D TSV
US11013745	80	79		Triazolopyrimidine, triazolopyridine compounds, and the composition thereof for treating PRC2-mediated diseases	SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES; SUZHOU SUPLEAD LIFE SCIENCES CO., LTD.	11/22/21	2D 3D TSV
US11014963	205	202		Trifluoromethylpropanamide derivatives as HTRA1 inhibitors	Hoffmann-La Roche Inc.	11/22/21	2D 3D TSV
US11008338	48	25	HGNC:934 HGNC:933	C5-C6-oxacyclic fused iminothiazine dioxide compounds bearing an ether linker as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp.	11/15/21	2D 3D TSV
US11008314	623	155	HGNC:1133 HGNC:6193 HGNC:6171 HGNC:12434	Compounds and methods for modulating interleukin-2-inducible t-cell kinase	Corvus Pharmaceuticals, Inc.	11/15/21	2D 3D TSV
US11008336	22	8	HGNC:10259 HGNC:10258	Compounds useful for inhibiting RORγt	Eli Lilly and Company	11/15/21	2D 3D TSV
US11007200	16	8	HGNC:8157	Cycloalkyl-diamines for the treatment of pain	MediSynergics, LLC	11/14/21	2D 3D TSV
US11008301	42	21	HGNC:3827 HGNC:3826	Piperidinone formyl peptide 2 receptor agonists	Bristol-Myers Squibb Company	11/14/21	2D 3D TSV
US11008312	373	359		Pyridazine derivatives as RORc modulators	Genentech, Inc.	11/14/21	2D 3D TSV
US11008308	435	420	HGNC:29232	Quinazolinones as PARP14 inhibitors	Ribon Therapeutics Inc.	11/14/21	2D 3D TSV
US11008304	85	85	HGNC:6857	Tetrazole containing apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	11/14/21	2D 3D TSV
US11000525	30	15	HGNC:7218 HGNC:12015	1-[2-(aminomethyl)benzyl]-2-thioxo-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-ones as inhibitors of myeloperoxidase	ASTRAZENECA AB	11/08/21	2D 3D TSV
US11001596	70	8	HGNC:5383 HGNC:5382	7-phenylethylamino-4H-pyrimido[4,5-d][1,3]oxazin-2-one compounds as mutant IDH1 and IDH2 inhibitors	Eli Lilly and Company	11/08/21	2D 3D TSV
US11001586	178	88	HGNC:7027 HGNC:12446	Alkyl pyrrolopyrimidine analogs and methods of making and using same	The University of North Carolina at Chapel Hill	11/08/21	2D 3D TSV
USRE48547	6	6	HGNC:6027	Aminopyrimidinecarboxamides as CXCR2 modulators	Syntrix Biosystems Inc.	11/08/21	2D 3D TSV
US11001575	923	899	HGNC:6871	Benzolactam compounds as protein kinase inhibitors	OTSUKA PHARMACEUTICAL CO., LTD.	11/08/21	2D 3D TSV
US11000528	26	11		Compound useful for the treatment of degenerative and inflammatory diseases	GALAPAGOS NV	11/08/21	2D 3D TSV
US10995099	93	59	HGNC:85 HGNC:84	Compounds and their uses as ACC inhibitors	Nanjing Ruijie Pharmatech Co., Ltd.	11/08/21	2D 3D TSV
US11000515	25	25		Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease	Shy Therapeutics LLC	11/08/21	2D 3D TSV
US11001555	22	22		Difluoroketamide derivatives as HTRA1 inhibitors	Hoffman-La Roche Inc.	11/08/21	2D 3D TSV
US11001583	16	16		Dihydropyrrolopyridine inhibitors of ROR-gamma	Vitae Pharmaceuticals, LLC	11/08/21	2D 3D TSV
US11001600	13	13	HGNC:2771	Disubstituted compounds for treatment of medical disorders	Achillion Pharmaceuticals, Inc.	11/08/21	2D 3D TSV
US11001568	170	44	HGNC:29012 HGNC:17071 HGNC:18039	Histone demethylase inhibitors	CELGENE QUANTICEL RESEARCH, INC.	11/08/21	2D 3D TSV
US11001578	188	92	HGNC:6371 HGNC:6357	N-((HET)arylmethyl)-heteroaryl-carboxamides compounds as plasma kallikrein inhibitors	KALVISTA PHARMACEUTICALS LIMITED	11/08/21	2D 3D TSV
US11001589	51	51	HGNC:3650	Pyrazole derivatives useful as 5-lipoxygenase activating protein (FLAP) inhibitors	ASTRAZENECA AB	11/08/21	2D 3D TSV
US11001595	32	13	HGNC:3763 HGNC:2861 HGNC:6307 HGNC:8804 HGNC:3236	Pyrimidine compounds and pyrimido indole compounds and methods of use	Duquesne University of The Holy Spirit	11/08/21	2D 3D TSV
US11001572	40	10	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Pyrimidine derivative, method for preparing same and use thereof in medicine	TBA	11/08/21	2D 3D TSV
US11001561	146	136	HGNC:9644	Pyrimidinone derivatives as SHP2 antagonists	Merck Patent GmbH	11/08/21	2D 3D TSV
US11001563	81	81	HGNC:550	SSAO inhibitor	TBA	11/08/21	2D 3D TSV
US10995070	15	15	HGNC:84	Acetyl-CoA carboxylase modulators	Monsanto Technology LLC	11/04/21	2D 3D TSV
US10994015	521	108	HGNC:3430 HGNC:3431 HGNC:3236	EGFR proteolysis targeting chimeric molecules and associated methods of use	ARVINAS OPERATIONS, INC.; YALE UNIVERSITY	11/04/21	2D 3D TSV
US10995072	124	57	HGNC:3538	Inhibitors of protease-activated receptor-2	Heptares Therapeutics Limited	11/04/21	2D 3D TSV
US10995088	309	162	HGNC:6833 HGNC:6834 HGNC:2671 HGNC:6664 HGNC:6666	Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer	THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL	11/04/21	2D 3D TSV
US10995073	253	218	HGNC:8605 HGNC:270	PARG inhibitory compounds	Cancer Research Technology Limited	11/04/21	2D 3D TSV
US10995084	192	116	HGNC:16709	Pyrrolidine derivative	KISSEI PHARMACEUTICAL CO., LTD.	11/04/21	2D 3D TSV
US10995090	21	19	HGNC:7056	Substituted dihydrobenzofuran glycosidase inhibitors	Asceneuron SA	11/04/21	2D 3D TSV
US10995089	92	92	HGNC:6871	Zaindole derivatives and their use as ERK kinase inhibitors	AGV DISCOVERY; INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS); UNIVERSITE DE MONTPELLIER	11/04/21	2D 3D TSV
US10988455	108	53	HGNC:262 HGNC:263	1,2,4-triazine-4-amine derivatives	Heptares Therapeutics Limited	11/01/21	2D 3D TSV
US10988502	64	32	HGNC:6561 HGNC:6563	Alpha-D-galactoside inhibitors of galectins	GALECTO BIOTECH AB	11/01/21	2D 3D TSV
US10988458	71	70	HGNC:6857	Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	11/01/21	2D 3D TSV
US10988459	91	77		Bicyclic lactams and methods of use thereof	Genentech, Inc.	11/01/21	2D 3D TSV
US10988445	310	136		Compounds	AstraZeneca AB	11/01/21	2D 3D TSV
US10988482	108	99	HGNC:17967	IRAK4 inhibitor and use thereof	BEIJING HANMI PHARMACEUTICAL CO., LTD.	11/01/21	2D 3D TSV
US10988507	2	2		Immunomodulators	bristol-myers squibb company	11/01/21	2D 3D TSV
US10987354	24	23		Inhibitors of influenza virus replication and uses thereof	SUNSHINE LAKE PHARMA CO., LTD.	11/01/21	2D 3D TSV
US10988451	457	440		MCL-1 inhibitors	Gilead Sciences, Inc.	11/01/21	2D 3D TSV
US10988481	66	20	HGNC:8153 HGNC:8154 HGNC:8156	Potent and selective mu opioid receptor modulators	Virginia Commonwealth University	11/01/21	2D 3D TSV
US10988462	37	37	HGNC:11036	Pyrazole compounds substituted with heteroaryl and pharmaceutical use thereof	Japan Tobacco Inc.	11/01/21	2D 3D TSV
US10988478	551	532	HGNC:17967	Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators	Genentech, Inc.	11/01/21	2D 3D TSV
US10988463	79	55		Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors	Pfizer Inc.	11/01/21	2D 3D TSV
US10988487	242	204	HGNC:6059	Substituted n′-hydroxycarbamimidoyl-1,2,5-oxadiazole compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors	Merck Sharp & Dohme Corp.	11/01/21	2D 3D TSV
US10988476	635	140	HGNC:1780 HGNC:1771 HGNC:1778 HGNC:1722 HGNC:1777 HGNC:1774 HGNC:1773	Substituted pyrimidines as cyclin-dependent kinase inhibitors	SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.	11/01/21	2D 3D TSV
US10981917	230	229	HGNC:9462	Heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same	Daewoong Pharmaceutical Co., Ltd.	10/27/21	2D 3D TSV
US10981916	25	25		Substituted pyrazolopyrimidinone compounds as PDE2 inhibitors	DART NEUROSCIENCE, LLC	10/27/21	2D 3D TSV
US10981926	3	1	HGNC:7978 HGNC:644	Substituted thiohydantoin derivatives as androgen receptor antagonists	Janssen Pharmaceutica NV	10/27/21	2D 3D TSV
US10981914	16	11	HGNC:15631 HGNC:6018	Toll-like receptor 7 (TLR7) agonists having a tricyclic moiety, conjugates thereof, and methods and uses therefor	Bristol-Myers Squibb Companay	10/27/21	2D 3D TSV
US10981904	67	61		1,3,4-thiadiazole compounds and their use in treating cancer	Cancer Research Technology Limited	10/26/21	2D 3D TSV
US10980781	21	18	HGNC:12630	6-amino-2,4-dihydropyrano [2,3-c] pyrazoles and methods of use	Purdue Research Foundation	10/26/21	2D 3D TSV
US10980815	468	113	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Aminopyrimidinyl compounds	Pfizer Inc.	10/26/21	2D 3D TSV
US10981887	50	25	HGNC:3467	Benzothiophene estrogen receptor modulators	G1 Therapeutics, Inc.	10/26/21	2D 3D TSV
US10981910	237	236	HGNC:19679	Biaryl kinase inhibitors	Bristol-Myers Squibb Company	10/26/21	2D 3D TSV
US10981882	19	19	HGNC:6059	Compound for inhibiting IDO, a manufacturing method and a use thereof	Shanghai JOYU Pharmatech Ltd.	10/26/21	2D 3D TSV
US10981881	16	8	HGNC:7967	FXR (NR1H4) modulating compounds	Gilead Sciences, Inc.	10/26/21	2D 3D TSV
US10981905	154	49	HGNC:10593 HGNC:10585 HGNC:10596	Heteroaryl-substituted sulfonamide compounds and their use as therapeutic agents	Xenon Pharmaceuticals Inc.	10/26/21	2D 3D TSV
US10981911	840	210		Imidazopyrrolopyridine as inhibitors of the JAK family of kinases	Janssen Pharmaceutica NV	10/26/21	2D 3D TSV
US10981896	43	22	HGNC:16870 HGNC:1925 HGNC:1470 HGNC:9377 HGNC:14311 HGNC:6871	Indolinone derivatives as inhibitors of maternal embryonic leucine zipper kinase	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM	10/26/21	2D 3D TSV
US10981899	9	5	HGNC:21285	Inhibitors of soluble adenylyl cyclase	Cornell University; Tri-Institutional Therapeutics Discovery Institute	10/26/21	2D 3D TSV
US10981898	89	85		Isoindolinone inhibitors of the MDM2-p53 interaction having anticancer activity	ASTEX THERAPEUTICS LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED	10/26/21	2D 3D TSV
US10980794	334	329		PRMT5 inhibitors and uses thereof	Epizyme, Inc.	10/26/21	2D 3D TSV
US10981906	110	51	HGNC:6190	Substituted pyrrolopyridine JAK inhibitors and methods of making and using the same	ACLARIS THERAPEUTICS, INC.	10/26/21	2D 3D TSV
US10981893	35	30	HGNC:6371	Therapeutic inhibitory compounds	ATTUNE PHARMACEUTICALS, INC.	10/26/21	2D 3D TSV
US10981879	189	164	HGNC:7218	Thioether triazolopyridine and triazolopyrimidine inhibitors of myeloperoxidase	Bristol-Myers Squibb Company	10/26/21	2D 3D TSV
US10980809	132	95	HGNC:6307 HGNC:9829 HGNC:1097	Urea-substituted aromatic ring-linked dioxane-quinazoline and -linked dioxane-quinoline compounds, preparation method therefor and use thereof	BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED	10/26/21	2D 3D TSV
US10975062	135	135		4-aminoquinazolinyl compounds as prolyl hydroxylase inhibitors	TBA	10/20/21	2D 3D TSV
US10975057	94	92		6-aminopyridin-3-yl pyrazoles as modulators of RORgT	Janssen Pharmaceutica NV	10/20/21	2D 3D TSV
US10975068	453	440		6-aminopyridin-3-yl thiazoles as modulators of RORγT	Janssen Pharmaceutica NV	10/20/21	2D 3D TSV
US10975066	25	25	HGNC:11138	Bis-heteroaryl derivatives as modulators of protein aggregation	UCB Biopharma SRL	10/20/21	2D 3D TSV
US10975080	72	71	HGNC:9644	Compounds and compositions for inhibiting the activity of SHP2	NOVARTIS AG	10/20/21	2D 3D TSV
US10975030	28	28	HGNC:5253	Grp94 selective inhibitors and uses thereof	University of Kansas; University of South Florida	10/20/21	2D 3D TSV
US10975075	471	134	HGNC:8978 HGNC:795 HGNC:8975 HGNC:3942 HGNC:8977 HGNC:8976	Imidazolonylquinolines and the use thereof as ATM kinase inhibitors	Merck Patent GmbH	10/20/21	2D 3D TSV
US10975058	8	4	HGNC:4840 HGNC:1133	Imidazolyl kinase inhibitors and uses thereof	Dana-Farber Cancer Institute, Inc.	10/20/21	2D 3D TSV
US10975084	185	185	HGNC:18039	KDM5 inhibitors	Merck Sharp & Dohme Corp.	10/20/21	2D 3D TSV
US10975049	22	22		Nicotinyl alcohol ether derivative, preparation method therefor, and pharmaceutical composition and uses thereof	Institute of Materia Medica, Chinese Academy of Medical Sciences; Tianjin Chase Sun Pharmaceutical Co., LTD	10/20/21	2D 3D TSV
US10973817	147	146	HGNC:1925	Pharmaceutical compounds	SENTINEL ONCOLOGY LIMITED	10/20/21	2D 3D TSV
US10975037	228	225		Phenyl substituted pyrazoles as modulators of RORγt	Janssen Pharmaceutica NV	10/20/21	2D 3D TSV
US10975091	290	150	HGNC:6656	Pyridine derivative	Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD.	10/20/21	2D 3D TSV
US10975064	27	27		RIP1 inhibitory compounds and methods for making and using the same	Rigel Pharmaceuticals, Inc.	10/20/21	2D 3D TSV
US10975081	18	16	HGNC:18618	Substituted fused pyrazole compounds and their use as LRRK2 inhibitors	GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED	10/20/21	2D 3D TSV
US10975056	659	644	HGNC:2976	Substituted pyridines as inhibitors of DNMT1	GlaxoSmithKline Intellectual Property Development Limited; Cancer Research Technology Ltd.	10/20/21	2D 3D TSV
US10968216	332	297	HGNC:2867	4,5-annulated 1,2,4-triazolones	BAYER AKTIENGESELLSCHAFT; BAYER PHARMA AKTIENGESELLSCHAFT; THE BROAD INSTITUTE, INC.; PRESIDENT AND FELLOWS OF HARVARD COLLEGE; THE GENERAL HOSPITAL CORPORATION	10/09/21	2D 3D TSV
US10968163	97	34	HGNC:3560 HGNC:3557	Alpha-truxillic acid derivatives and pharmaceutical compositions thereof	The Research Foundation for the State University of New York	10/09/21	2D 3D TSV
US10968188	153	114	HGNC:8803 HGNC:76 HGNC:6342	Benzothiazol compounds and methods using the same for treating neurodegenerative disorders	1st Biotherapeutics, Inc.	10/09/21	2D 3D TSV
US10968198	35	35	HGNC:7097	Biaryltriazole inhibitors of macrophage migration inhibitory factor	Yale University	10/09/21	2D 3D TSV
US10968199	30	29	HGNC:6857	Cycloalkyl-containing apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	10/09/21	2D 3D TSV
US10968242	106	35		Cyclopentane-based modulators of STING (stimulator of interferon genes)	Pfizer Inc.	10/09/21	2D 3D TSV
US10968213	375	107	HGNC:6833 HGNC:6834 HGNC:29079	Cyclopropanamine compound and use thereof	Takeda Pharmaceutical Company Limited	10/09/21	2D 3D TSV
US10968223	155	155	HGNC:550	Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors	Proximagen, LLC	10/09/21	2D 3D TSV
US10968227	45	45	HGNC:4596	Isoquinoline ether compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction	Vanderbilt University	10/09/21	2D 3D TSV
US10966985	52	13	HGNC:10261	Macrocyclic compounds as ROS1 kinase inhibitors	Array BioPharma Inc.	10/09/21	2D 3D TSV
US10968215	227	189	HGNC:3527	Pyrido five-element aromatic ring compound, preparation method therefor and use thereof	SHANGHAI HAIHE PHARMACEUTICAL CO., LTD.; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES	10/09/21	2D 3D TSV
US10966980	1100	273	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyrrolo[2,3-d]pyrimidine derivatives	Pfizer Inc.	10/09/21	2D 3D TSV
US10968221	13	13	HGNC:29079	Substituted [1,2,4]triazolo[1,5-a]pyrazines as LSD1 inhibitors	Incyte Corporation	10/09/21	2D 3D TSV
US10967060	22	22	HGNC:6059	Synergistic combination of immunologic inhibitors for the treatment of cancer	The University of Chicago	10/09/21	2D 3D TSV
US10968236	184	91	HGNC:6192 HGNC:12440	TYK2 inhibitors and uses thereof	Nimbus Lakshmi, Inc.	10/09/21	2D 3D TSV
US10966987	23	23	HGNC:6307	Therapeutic compounds and uses thereof	Kala Pharmaceuticals, Inc.	10/09/21	2D 3D TSV
US10968172	90	90		USP30 inhibitors	Mitobridge, Inc.	10/09/21	2D 3D TSV
US10961236	249	63	HGNC:8975 HGNC:8977 HGNC:8976	(S)-2-(1-cyclopropylethyl)-5-(4-methyl-2-((6-(2-oxopyrrolidin-1-yl)pyridin-2-yl)amino) thiazol-5-yl)-7-(methylsulfonyl)isoindolin-1-one as a phosphatidylinositol 3-kinase inhibitor	AstraZeneca AB	10/04/21	2D 3D TSV
US10961241	73	66		Chemical compounds	AstraZeneca AB	10/04/21	2D 3D TSV
US10961242	81	80	HGNC:3357	Compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same	LegoChem Biosciences, Inc.	10/04/21	2D 3D TSV
US10961198	66	66	HGNC:7967	Farnesoid X receptor agonists and uses thereof	METACRINE, INC.	10/04/21	2D 3D TSV
US10961237	146	145	HGNC:1133	Inhibiting agents for Bruton's tyrosine kinase	BIOGEN MA INC.	10/04/21	2D 3D TSV
US10961228	198	66		JAK1 selective inhibitors	ASTRAZENECA AB	10/04/21	2D 3D TSV
US10961249	21	21		Modulators of the sigma-2 receptor and their method of use	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	10/04/21	2D 3D TSV
US10961233	46	45		Oxazole derivatives for use in the treatment of cancer	LIFEARC	10/04/21	2D 3D TSV
US10961256	3	3	HGNC:10894	PRMT5 inhibitors	CTXT PTY LTD	10/04/21	2D 3D TSV
US10961247	365	180	HGNC:1133 HGNC:6193	Pyrazolopyrimidine derivatives as kinase inhibitor	Daewoong Pharmaceutical Co., Ltd.	10/04/21	2D 3D TSV
US10961252	34	34	HGNC:1037	Quinazoline and indole compounds to treat medical disorders	Achillion Pharmaceuticals, Inc.	10/04/21	2D 3D TSV
US10961200	522	512	HGNC:6535	Small molecule inhibitors of lactate dehydrogenase and methods of use thereof	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; VANDERBILT UNIVERSITY; THE UAB RESEARCH FOUNDATION; THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA	10/04/21	2D 3D TSV
US10961232	603	568	HGNC:882	Substituted pyrazines as ATR kinase inhibitors	VERTEX PHARMACEUTICALS INCORPORATED	10/04/21	2D 3D TSV
US10960005	122	119	HGNC:29079	Treatment of relapsed and/or refractory solid tumors and non-hodgkin's lymphomas	CELGENE QUANTICEL RESEARCH, INC.	10/04/21	2D 3D TSV
US10954228	149	145	HGNC:6535	1 H-pyrazol-1-yl-thiazoles as inhibitors of lactate dehydrogenase and methods of use thereof	THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA; THE UAB RESEARCH FOUNDATION; VANDERBILT UNIVERSITY; NATIONAL INSTITUTES OF HEALTH, UNITED STATES DEPT. OF HEALTH AND HUMAN SERVICES	09/28/21	2D 3D TSV
US10954253	76	75	HGNC:12761	1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one derivative as Wee1 inhibitor	SHIJIAZHUANG SAGACITY NEW DRUG DEVELOPMENT CO., LTD.	09/28/21	2D 3D TSV
US10952995	27	27	HGNC:6863	Azaindoles as inhibitors of HPK1	Genentech, Inc.	09/28/21	2D 3D TSV
US10954216	119	90	HGNC:171	BMP-signal-inhibiting compound	RIKEN; THE UNIVERSITY OF TOKYO	09/28/21	2D 3D TSV
US10954244	11	11	HGNC:6307	Compounds and uses thereof	Kala Pharmaceuticals, Inc.	09/28/21	2D 3D TSV
US10954240	60	60		Compounds inhibiting leucine-rich repeat kinase enzyme activity	Merck Sharp & Dohme Corp.	09/28/21	2D 3D TSV
US10954241	320	108	HGNC:6307 HGNC:9967	Heterocyclic compounds as ret kinase inhibitors	Cancer Research Technology Limited	09/28/21	2D 3D TSV
US10953012	420	239	HGNC:2459	Heterocyclic compounds for the inhibition of pask	BioEnergenix LLC	09/28/21	2D 3D TSV
US10954237	56	19	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	JAK inhibitors containing a 4-membered heterocyclic amide	Theravance Biopharma R&D IP, LLC	09/28/21	2D 3D TSV
US10947254	1048	261	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Methods for treating ulcerative colitis using 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile	Theravance Biopharma R&D IP, LLC	09/28/21	2D 3D TSV
US10952992	100	97	HGNC:9665	Methods of treating intraocular pressure with activators of Tie-2	AERPIO PHARMACEUTICALS, INC.	09/28/21	2D 3D TSV
US10954214	449	444	HGNC:6819	Pyrazole derivatives as MALT1 inhibitors	Janssen Pharmaceutica NV	09/28/21	2D 3D TSV
US10954225	28	15		Selective NR2B antagonists	Bristol-Myers Squibb Company	09/28/21	2D 3D TSV
US10954217	86	43	HGNC:8157	Sigma receptor binders	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM	09/28/21	2D 3D TSV
US10954243	22	22		Substituted heterocyclic inhibitors of PTPN11	NAVIRE PHARMA, INC.	09/28/21	2D 3D TSV
US10954193	147	134	HGNC:6943 HGNC:992 HGNC:990	Substituted indole Mcl-1 inhibitors	Vanderbilt University	09/28/21	2D 3D TSV
US10953005	1229	556	HGNC:9967	Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors	Array Biopharma Inc.	09/28/21	2D 3D TSV
US10947203	176	88	HGNC:7968	1,4,5-substituted 1,2,3-triazole analogues as antagonists of the pregnane X receptor	ST. JUDE CHILDREN''S RSEARCH HOSPITAL	09/26/21	2D 3D TSV
US10947218	616	87		Aminopyridine derivatives and their use as selective ALK-2 inhibitors	NOVARTIS AG	09/26/21	2D 3D TSV
US10947196	8	4	HGNC:285 HGNC:286	Beta adrenergic agonist and methods of using the same	CuraSen Therapeutics, Inc.	09/26/21	2D 3D TSV
US10947230	162	54	HGNC:3690 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR inhibitors	Incyte Corporation; Incyte Holdings Corporation	09/26/21	2D 3D TSV
US10947226	23	23		Bicyclic pyridone lactams and methods of use thereof	Genentech, Inc.	09/26/21	2D 3D TSV
US10945994	17	3	HGNC:11708 HGNC:6059	Combinations comprising a pyrrolidine-2,5-dione IDO1 inhibitor and an anti-body	Pfizer Inc.; iTEOS THERAPEUTICS	09/26/21	2D 3D TSV
US10947229	48	12	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Dimethyl amino azetidine amides as JAK inhibitors	Theravance Biopharma R&D IP, LLC	09/26/21	2D 3D TSV
US10947243	391	79	HGNC:11390 HGNC:4617 HGNC:3765	Heteroaryl SYK inhibitors	Boehringer Ingelheim International GmbH	09/26/21	2D 3D TSV
US10947215	458	449		Heteroaryl compounds and their use as therapeutic drugs	Dong-A Socio Holdings Co., Ltd.	09/26/21	2D 3D TSV
US10947222	72	72	HGNC:16940	Indole derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2	Merck Sharp & Dohme Corp.	09/26/21	2D 3D TSV
US10947210	164	135		Inhibitors of Hepatitis C virus polymerase	COCRYSTAL PHARMA, INC.	09/26/21	2D 3D TSV
US10947252	558	547		Inhibitors of KEAP1-Nrf2 protein-protein interaction	Janssen Pharmaceutica NV	09/26/21	2D 3D TSV
US10946019	33	33	HGNC:10477	Nurr1:RXR activating compounds for simultaneous treatment of symptoms and pathology of Parkinson's disease	TBA	09/26/21	2D 3D TSV
US10947234	36	12	HGNC:10894	PRMT5 inhibitors	Merck Sharp & Dohme Corp.	09/26/21	2D 3D TSV
US10947241	26	26		Phenyl phthalazine derivative, method for the preparation thereof, and pharmaceutical composition comprising the same	Seoul National University Hospital	09/26/21	2D 3D TSV
US10947223	72	18	HGNC:2529 HGNC:933	Substituted oxazines as beta-secretase inhibitors	Amgen Inc.	09/26/21	2D 3D TSV
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US10947251	76	38	HGNC:10597	Therapeutic compounds and methods of use thereof	GENENTECH, INC.	09/26/21	2D 3D TSV
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US10947239	8	1	HGNC:8778	[1,2,4]triazolo[1,5-a]pyrimidin-7-yl compound	Janssen Pharmaceutica NV	09/26/21	2D 3D TSV
US10941129	26	26		Benzyl phenyl ether derivative, preparation method therefor, and pharmaceutical composition and uses thereof	Institute of Materia Medica, Chinese Academy of Medical Sciences; Tianjin Chase Sun Pharmaceutical Co., LTD	09/20/21	2D 3D TSV
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US10940139	25	25		Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease	Shy Therapeutics LLC	09/20/21	2D 3D TSV
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US10941115	196	72	HGNC:11491 HGNC:11283 HGNC:4616 HGNC:6524 HGNC:6876	Kinase inhibitors	Oxular Acquisitions Limited	09/20/21	2D 3D TSV
US10941146	31	31		Methods for inhibiting fascin	NOVITA PHARMACEUTICALS, INC.; CORNELL UNIVERSITY	09/20/21	2D 3D TSV
US10941138	193	88	HGNC:1399	Quinoline and isoquinoline derivatives for treating pain and pain related conditions	ESTEVE PHARMACEUTICALS, S.A.	09/20/21	2D 3D TSV
US10934296	665	131	HGNC:6735 HGNC:4037 HGNC:1133 HGNC:11283 HGNC:6524	4-imidazopyridazin-1-yl-benzamides as Btk inhibitors	Merck Sharp & Dohme B.V.	09/12/21	2D 3D TSV
US10934297	286	143	HGNC:4617 HGNC:3091	5-heteroaryl substituted indazole-3-carboxamides and preparation and use thereof	Samumed, LLC	09/12/21	2D 3D TSV
US10934303	124	28	HGNC:3474 HGNC:3473 HGNC:3471 HGNC:3467	Aryl ethene derivative and pharmaceutical composition containing same as active ingredient	DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION; KYUNGPOOK NATIONAL UNIVERSITY HOSPITAL; KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION	09/12/21	2D 3D TSV
US10933063	258	214	HGNC:6735 HGNC:1133 HGNC:6171 HGNC:11719 HGNC:3236 HGNC:6524	Bruton's tyrosine kinase inhibitors	Suzhou Baijibugong Pharmaceutical Technology Co., Ltd.	09/12/21	2D 3D TSV
US10934285	61	61		Compounds and compositions for inhibiting the activity of SHP2	NOVARTIS AG	09/12/21	2D 3D TSV
US10934310	484	472	HGNC:1133	Inhibitors of Bruton's tyrosine kinase and method of their use	Janssen Pharmaceutica NV	09/12/21	2D 3D TSV
US10934288	241	236	HGNC:6863	Pyrazolopyridine compounds and uses thereof	Incyte Corporation	09/12/21	2D 3D TSV
US10934305	54	32	HGNC:10852 HGNC:10850	SHMT inhibitors	The Trustees of Princeton University	09/12/21	2D 3D TSV
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US10934304	88	87	HGNC:6871	Spirocyclic compounds	Recurium IP Holdings, LLC	09/12/21	2D 3D TSV
US10934294	124	60		Substituted pyrazolo[3,4-d]pyrimidines as PDE9 inhibitors	Merck Sharp & Dohme Corp.	09/12/21	2D 3D TSV
US10927106	45	44	HGNC:3091	Benzothiazole derivatives as DYRK1 inhibitors	PHARMASUM THERAPEUTICS AS	09/06/21	2D 3D TSV
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US10927076	96	48	HGNC:5258 HGNC:5253	HSP90B N-terminal isoform-selective inhibitors	University of Kansas	09/06/21	2D 3D TSV
US10927111	79	62	HGNC:9829	Inhibitors of RAF kinases	KINNATE BIOPHARMA INC.	09/06/21	2D 3D TSV
US10927079	74	69	HGNC:8031	Intermediate compound of novel tetrahydronaphthyl urea derivative	MOCHIDA PHARMACEUTICAL CO., LTD.	09/06/21	2D 3D TSV
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US10927128	113	112	HGNC:575	Oxadiazaspiro compounds for the treatment of drug abuse and addiction	ESTEVE PHARMACEUTICALS. S.A.	09/06/21	2D 3D TSV
US10927105	323	248	HGNC:17038	Pyrazole MAGL inhibitors	LUNDBECK LA JOLLA RESEARCH CENTER, INC.	09/06/21	2D 3D TSV
US10927086	86	48	HGNC:6059	Substituted sulfoximine compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors	Merck Sharp & Dohme Corp.	09/06/21	2D 3D TSV
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US10925840	52	26	HGNC:285 HGNC:286	Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas	The USA, as represented by the Secretary, Department of Health and Human Services; SRI International	09/06/21	2D 3D TSV
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US10918640	19	18	HGNC:3553	Azetidine derivatives	Vernalis (R&D) Ltd.	09/02/21	2D 3D TSV
US10919859	57	56	HGNC:4498	Benzylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof	Boehringer Ingelheim International GmbH	09/02/21	2D 3D TSV
US10919843	18	9	HGNC:4910	Cannabidiol derivatives as inhibitors of the HIF prolyl hydroxylases activity	Emerald Health Pharmaceuticals Inc.	09/02/21	2D 3D TSV
US10919885	926	463	HGNC:10571 HGNC:21088	Compounds and uses thereof	Yumanity Therapeutics, Inc.	09/02/21	2D 3D TSV
US10919856	36	18		Cyclohexene compounds and use thereof	GUANGZHOU HENOVCOM BIOSCIENCE CO. LTD.	09/02/21	2D 3D TSV
US10919862	9	6		Fused imidazoles as mIDH1 inhibitors	BAYER PHARMA AKTIENGESELLSCHAFT	09/02/21	2D 3D TSV
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US10919899	20	12	HGNC:1133 HGNC:6171 HGNC:11719 HGNC:12434	Imidazopyrazine compounds, preparation methods and uses thereof	DONGGUAN ZHENXING-BEITE MEDICINE TECHNOLOGY CO., LTD.	09/02/21	2D 3D TSV
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US10918642	68	68	HGNC:3255	N-(substituted-phenyl)-sulfonamide derivatives as kinase inhibitors	Nerviano Medical Sciences S.R.L.	09/02/21	2D 3D TSV
US10919890	4	1	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders	GALAPAGOS NV	09/02/21	2D 3D TSV
US10919913	67	56	HGNC:6973	Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-p53 inhibitors	Boehringer Ingelheim International GmbH	09/02/21	2D 3D TSV
US10918645	91	51	HGNC:6192	Substituted tricyclic heterocyclic compounds and use thereof	LIFEARC; SUZHOU YABAO PHARMACEUTICAL R&D CO., LTD.	09/02/21	2D 3D TSV
US10919869	50	49	HGNC:2867	Thiazole derivative and applications	EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY	09/02/21	2D 3D TSV
US10919858	71	70	HGNC:17989	Thioacetate compounds, compositions and methods of use	Ardea Biosciences, Inc	09/02/21	2D 3D TSV
US10919895	66	37	HGNC:15631 HGNC:6018	Toll-like receptor 7 (TLR7) agonists having a pyridine or pyrazine moiety, conjugates thereof, and methods and uses therefor	Bristol-Myers Squibb Company	09/02/21	2D 3D TSV
US10919911	81	80	HGNC:6857	Tricyclic ASK1 inhibitors	TERNS, INC.	09/02/21	2D 3D TSV
US10913710	100	99	HGNC:8788	Benzene disulfonamide for the treatment of cancer	Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V	08/30/21	2D 3D TSV
US10913735	14	14	HGNC:11138	Bis-heteroaryl derivatives as modulators of protein aggregation	UCB Biopharma SRL	08/30/21	2D 3D TSV
US10912773	302	107	HGNC:8775 HGNC:8774 HGNC:8776	Combinations comprising substituted imidazo[1,5-a]pyrazinones as PDE1 inhibitors	H. Lundbeck A/S	08/30/21	2D 3D TSV
US10913740	112	16	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	JAK kinase inhibitor compounds for treatment of respiratory disease	Theravance Biopharma R&D IP, LLC	08/30/21	2D 3D TSV
US10913744	54	20		LRRK2 inhibitors and methods of making and using the same	DANA-FARBER CANCER INSTITUTE, INC.	08/30/21	2D 3D TSV
US10913745	49	47	HGNC:10548	Octahydro-pyrrolo[3,4-c]-pyrrole derivatives and analogs thereof as autotaxin inhibitors	Hoffmann-La Roche Inc.	08/30/21	2D 3D TSV
US10913742	110	110	HGNC:497	Oxadiazolones as transient receptor potential channel inhibitors	Genentech, Inc.	08/30/21	2D 3D TSV
US10913711	189	59		Potent and selective inhibitors of monoamine transporters; method of making; and use thereof	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES	08/30/21	2D 3D TSV
US10912774	144	67	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Pyrimidine FGFR4 inhibitors	EISAI R&D MANAGEMENT CO., LTD.	08/30/21	2D 3D TSV
US10913746	124	111	HGNC:9922	Substituted 4-phenylpiperidines, their preparation and use	The Trustees of Columbia University in the City of New York	08/30/21	2D 3D TSV
US10913733	54	50	HGNC:7056	Substituted piperidines thiazolyl acetamides as glycosidase inhibitors and uses thereof	Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp.	08/30/21	2D 3D TSV
US10913753	410	219		Thienopyridine carboxamides as ubiquitin-specific protease inhibitors	VALO EARLY DISCOVERY, INC.	08/30/21	2D 3D TSV
US10905688	302	111	HGNC:8775 HGNC:8774 HGNC:8776	Combinations comprising substituted imidazo[1,5-α]pyrazinones as PDE1 inhibitors	H. Lundbeck A/S	08/22/21	2D 3D TSV
US10906896	132	42	HGNC:77 HGNC:76 HGNC:6342	Compositions and methods for inhibiting kinases	Inhibikase Therapeutics, Inc.	08/22/21	2D 3D TSV
US10906900	62	14	HGNC:11138	Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases	CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)	08/22/21	2D 3D TSV
US10906905	88	52	HGNC:6307 HGNC:6876	Five-membered heteroaryl ring bridged ring derivative, preparation method therefor and medical use thereof	Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd.	08/22/21	2D 3D TSV
US10906920	68	65		Heterocyclic compounds as immunomodulators	Incyte Corporation	08/22/21	2D 3D TSV
US10906878	7	7	HGNC:1133	Kinase inhibitors for the treatment of disease	DANA FARBER CANCER INSTITUTE, INC.	08/22/21	2D 3D TSV
US10906888	205	198		Pyrimidine carboxamides as inhibitors of Vanin-1 enzyme	Pfizer Inc.	08/22/21	2D 3D TSV
US10905687	20	20		Substituted piperazines as ROR-gamma modulators	ESCALIER BIOSCIENCES B.V.	08/22/21	2D 3D TSV
US10906915	372	370	HGNC:8783	Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors	LEO Pharma A/S	08/22/21	2D 3D TSV
US10906890	112	103	HGNC:339	Triazole phenyl compounds as agonists of the APJ receptor	AMGEN INC.	08/22/21	2D 3D TSV
US10899772	34	34	HGNC:17967	IRAK4 modulators	Genentech, Inc.	08/16/21	2D 3D TSV
US10899774	71	71	HGNC:17967	IRAK4 modulators	Genentech, Inc.	08/16/21	2D 3D TSV
US10899741	9	4	HGNC:6307 HGNC:10020 HGNC:6876	3,4-bipyridyl pyrazole derivative, and preparation method therefor and medical application thereof	Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd.	08/15/21	2D 3D TSV
US10899755	32	32	HGNC:6863	Benzothiazole compounds and uses thereof	Incyte Corporation	08/15/21	2D 3D TSV
US10899764	56	33	HGNC:11708 HGNC:6059	Imidazo isoindole derivative, preparation method therefor and medical use thereof	JIANGSU HENGRUI MEDICINE CO., LTD.; SHANGHAI HENGRUI PHRMACEUTICAL CO., LTD.	08/15/21	2D 3D TSV
US10899769	268	124		Imidazopiperazinone inhibitors of transcription activating proteins	Board of Regents, The University of Texas System	08/15/21	2D 3D TSV
US10899753	110	110	HGNC:1133	Inhibiting agents for Bruton's tyrosine kinase	BIOGEN MA INC.	08/15/21	2D 3D TSV
US10899735	432	427		PD-1/PD-L1 inhibitors	Gilead Sciences, Inc.	08/15/21	2D 3D TSV
US10899756	28	23	HGNC:8784 HGNC:8785	Phosphodiesterase inhibitors and uses thereof	The Trustees of Columbia University in the City of New York	08/15/21	2D 3D TSV
US10899738	386	378	HGNC:7010	Piperidines as menin inhibitors	THE REGENTS OF THE UNIVERSITY OF MICHIGAN	08/15/21	2D 3D TSV
US10898481	73	38	HGNC:262 HGNC:263 HGNC:264	Pyrazine compounds and uses thereof	TBA	08/15/21	2D 3D TSV
US10894048	73	49	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Antitumor drug for intermittent administration of FGFR inhibitor	Taiho Pharmaceutical Co., Ltd.	08/14/21	2D 3D TSV
US10894797	52	51	HGNC:9644	Fused tricyclic ring derivatives as SRC homology-2 phosphatase inhibitors	Nikang Therapeutics, Inc.	08/14/21	2D 3D TSV
US10894789	334	165	HGNC:4849 HGNC:4848	Halo-substituted piperidines as orexin receptor modulators	ASTRAZENECA AB; EOLAS THERAPEUTICS, INC.	08/14/21	2D 3D TSV
US10894784	652	648	HGNC:11584	Heteroarylbenzimidazole compounds	BAYER PHARMA AKTIENGESELLSCHAFT	08/14/21	2D 3D TSV
US10894052	36	35		Heterocyclic inhibitors of ATR kinase	Board of Regents, The University of Texas System; ChemPartner Corporation	08/14/21	2D 3D TSV
US10894038	20	19	HGNC:17989	Indolizine derivatives, composition and methods of use	SHANGHAI FOCHON PHARMACEUTICAL CO. LTD.; FOCHON PHARMACEUTICALS, LTD.	08/14/21	2D 3D TSV
US10894788	199	161		Inhibitors of cyclin-dependent kinases	KINNATE BIOPHARMA INC.	08/14/21	2D 3D TSV
US10894782	132	120	HGNC:12666	Modulators of P97 AAA ATPase activity	University of Pittsburgh—Of the Commonwealth System of Higher Education	08/14/21	2D 3D TSV
US10894803	4	4	HGNC:5467	Multi-functionalized polysaccharide compounds and use thereof for targeting the cation-independent mannose 6-phosphate receptor	NANOMEDSYN; Centre National de la Recherche Scientifique; Universite de Montpellier	08/14/21	2D 3D TSV
US10894807	103	102	HGNC:3788	PSMA imaging agents	Siemens Medical Solutions USA, Inc.	08/14/21	2D 3D TSV
US10894794	3	3	HGNC:3009	Substituted [1,2,4]triazolo[4,3-a]pyrazines as antidiabetics	King Abdulaziz University	08/14/21	2D 3D TSV
US10894786	141	46	HGNC:1778 HGNC:1733	Substituted pyrazole derivatives as selective CDK12/13 inhibitors	Aurigene Discovery Technologies Limited	08/14/21	2D 3D TSV
US10889546	85	74	HGNC:1232 HGNC:14661	Alkynyl pyridine prolyl hydroxylase inhibitor, and preparation method and medical use thereof	Jiangsu Hengrui Medicine Co., Ltd.	08/09/21	2D 3D TSV
US10889610	25	22	HGNC:6561 HGNC:6563	Alpha-D-galactoside inhibitors of galectins	GALECTO BIOTECH AB	08/09/21	2D 3D TSV
US10889589	161	157	HGNC:8031	Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain	Array BioPharma Inc.	08/09/21	2D 3D TSV
US10888561	14	14	HGNC:9843	CGRP receptor antagonists	Heptares Therapeutics Limited	08/09/21	2D 3D TSV
US10889569	62	32	HGNC:897 HGNC:895 HGNC:896	Condensed ring group azacyclobutyl triazole derivative, preparation method therefor and use thereof in medicine	Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd.	08/09/21	2D 3D TSV
US10889581	120	40	HGNC:934 HGNC:2529 HGNC:933	Cyclopropyl fused thiazine derivatives as beta-secretase inhibitors and methods of use	Amgen Inc.	08/09/21	2D 3D TSV
US10889552	29	29	HGNC:5253	Dihydroxybenzamide compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof, and medical use thereof	ONCOZEN CO.. LTD.	08/09/21	2D 3D TSV
US10889568	96	95	HGNC:12338	Inhibitors of TRPC6	Boehringer Ingelheim International GmbH	08/09/21	2D 3D TSV
US10888567	78	78	HGNC:6059	Inhibitors of tryptophan dioxygenases (IDO1 and TDO) and their use in therapy	Auckland UniServices Limited	08/09/21	2D 3D TSV
US10889591	69	69	HGNC:8795	PDE9 inhibitor and use thereof	Nanjing TransThera Biosciences Co. Ltd.	08/09/21	2D 3D TSV
US10889571	217	215		Substituted benzoimidazoles and imidazo[4,5-c]pyridines for treating certain leukemias	Terns, Inc.	08/09/21	2D 3D TSV
US10889555	279	268		Sulfonamide compound or salt thereof	Taiho Pharmaceutical Co., Ltd.	08/09/21	2D 3D TSV
US10889564	52	52	HGNC:2867	Tetrahydroindazoles and medical uses thereof	Genase Therapeutics B.V.	08/09/21	2D 3D TSV
US10889579	51	17	HGNC:934 HGNC:2529 HGNC:933	Thiazine derivatives as β-secretase inhibitors and methods of use	Amgen Inc.	08/09/21	2D 3D TSV
US10889592	39	21		Thienopyrazine carboxamides as ubiquitin-specific protease inhibitors	VALO EARLY DISCOVERY, INC.	08/09/21	2D 3D TSV
US10889595	7	7	HGNC:933	[1,3]thiazin-2-amine compound, application, and pharmaceutical composition	TETRANOV PHARMACEUTICAL CO., LTD.	08/09/21	2D 3D TSV
US10888550	33	33	HGNC:6819	Pyrazole derivatives as MALT1 inhibitors	Janssen Pharmaceutica NV	08/08/21	2D 3D TSV
US10881668	12	6	HGNC:13575 HGNC:1105	Acetamide thienotriazolodiazepines and uses thereof	Dana-Farber Cancer Institute, Inc.	08/01/21	2D 3D TSV
US10882857	17	17	HGNC:3357	Bicyclic compounds as ATX inhibitors	Hoffmann-La Roche Inc.	08/01/21	2D 3D TSV
US10882838	177	61	HGNC:2160	Cannabinergic compounds and uses thereof	NORTHEASTERN UNIVERSITY	08/01/21	2D 3D TSV
US10882844	48	48		Compounds useful as immunomodulators	Bristol-Myers Squibb Company	08/01/21	2D 3D TSV
US10882835	27	27	HGNC:29079	KDM1A inhibitors for the treatment of disease	Imago Biosciences, Inc.	08/01/21	2D 3D TSV
US10882859	12	3	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Kinase inhibitors	TOPIVERT PHARMA LIMITED	08/01/21	2D 3D TSV
US10882829	88	22	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pharmaceutical compounds	Sareum Limited	08/01/21	2D 3D TSV
US10882833	17	16		Phenylate derivative, preparation method therefor, and pharmaceutical composition and uses thereof	Institute of Materia Medica, Chinese Academy of Medical Sciences; Tianjin Chase Sun Pharmaceutical Co., LTD	08/01/21	2D 3D TSV
US10882866	148	137		Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors	Boehringer Ingelheim International GmbH	08/01/21	2D 3D TSV
US10881652	2116	812	HGNC:9967	Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors	Array Biopharma Inc.	08/01/21	2D 3D TSV
US10882855	56	19	HGNC:3528 HGNC:3529 HGNC:3535	Substituted pyrrolidines as factor XIa inhibitors for the treatment thromboembolic diseases	ONO PHARMACEUTICAL CO., LTD.	08/01/21	2D 3D TSV
US10882853	12	8	HGNC:6307 HGNC:7029	Tyrosine kinase inhibitor and application thereof	LaNova Medicines Limited	08/01/21	2D 3D TSV
US10870635	36	25	HGNC:934 HGNC:2529 HGNC:933	Compounds and their use as BACE1 inhibitors	ALLGENESIS BIOTHERAPEUTICS, INC.	07/26/21	2D 3D TSV
US10870651	52	40	HGNC:3697 HGNC:1780 HGNC:16870 HGNC:1771 HGNC:16627 HGNC:11283 HGNC:9410 HGNC:19007 HGNC:9967	Inhibitors of cyclin-dependent kinase 7 (CDK7)	Dana-Farber Cancer Institute, Inc.	07/26/21	2D 3D TSV
US10870660	278	138	HGNC:3023 HGNC:3024	Nitrogen-containing condensed ring compounds having dopamine D3 antagonistic effect	SHIONOGI & CO., LTD.	07/26/21	2D 3D TSV
US10870641	855	825		Pyridazinones as PARP7 inhibitors	Ribon Therapeutics, Inc.	07/26/21	2D 3D TSV
US10870639	27	18	HGNC:3765	Pyrimidine compounds and pharmaceutical compositions for preventing or treating cancers including the same	HANMI PHARM. CO.. LTD.	07/26/21	2D 3D TSV
US10870625	10	10	HGNC:2861	Zwitterionic propargyl-linked antifolates useful for treating bacterial infections	UNIVERSITY OF CONNECTICUT	07/26/21	2D 3D TSV
US10875847	13	9	HGNC:6190 HGNC:6192 HGNC:6193	Aminopyrazoles as selective janus kinase inhibitors	Intervet Inc.	07/25/21	2D 3D TSV
US10875829	6	2	HGNC:11050 HGNC:11048 HGNC:11049	Azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission	INTEGRATIVE RESEARCH LABORATORIES SWEDEN AB	07/25/21	2D 3D TSV
US10864192	4	4	HGNC:108	Compositions and methods for inhibiting brain trauma-induced neurodegeneration and related conditions	Aristea Translational Medicine Corporation	07/25/21	2D 3D TSV
US10869871	96	91	HGNC:5154	Compositions and methods of modulating short-chain dehydrogenase activity	CASE WESTERN RESERVE UNIVERSITY; THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM	07/25/21	2D 3D TSV
US10874634	43	23	HGNC:20581 HGNC:2603	Compounds and methods for inhibiting CYP26 enzymes	Queen''s University at Kingston	07/25/21	2D 3D TSV
US10875867	202	90	HGNC:8772	Cyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxyamide	Boehringer Ingelheim International GmbH	07/25/21	2D 3D TSV
US10875851	183	174	HGNC:3530	Factor XIIa inhibitors	MERCK SHARP & DOHME CORP.	07/25/21	2D 3D TSV
US10875852	156	151	HGNC:1133	Heteroaromatic compounds as BTK inhibitors	Boehringer Ingelheim International GmbH	07/25/21	2D 3D TSV
US10874687	12	3		Highly active compounds against COVID-19	Atea Pharmaceuticals, Inc.	07/25/21	2D 3D TSV
US10870618	46	30	HGNC:4852 HGNC:4854 HGNC:4853	Histone deacetylase inhibitors and uses thereof	MUSC FOUNDATION FOR RESEARCH DEVELOPMENT	07/25/21	2D 3D TSV
US10874683	39	26		N4-hydroxycytidine and derivatives and anti-viral uses related thereto	Emory University	07/25/21	2D 3D TSV
US10874669	32	16	HGNC:3023 HGNC:3024	Neuroprotective agents for treatment of neurodegenerative diseases	WAYNE STATE UNIVERSITY	07/25/21	2D 3D TSV
US10869929	22	22		Phosphonate linkers and their use to facilitate cellular retention of compounds	MERCK SHARP & DOHME CORP.	07/25/21	2D 3D TSV
US10874675	34	34	HGNC:23357	Pteridine dione monocarboxylate transporter inhibitors	THE SCRIPPS RESEARCH INSTITUTE	07/25/21	2D 3D TSV
US10875863	26	25	HGNC:10020	RIPK2 inhibitors and method of treating cancer with same	UNIVERSITY HEALTH NETWORK	07/25/21	2D 3D TSV
US10875864	120	102	HGNC:6251	Substituted imidazo[1,2-B]pyridazines as protein kinase inhibitors	SUMITOMO DAINIPPON PHARMA ONCOLOGY, INC.	07/25/21	2D 3D TSV
US10875832	3	3		Substituted pyrimidines for treating bacterial infections	FORGE THERAPEUTICS, INC.	07/25/21	2D 3D TSV
US10874640	138	136		Substituted pyrrolizine compounds and uses thereof	GILEAD SCIENCES, INC.	07/25/21	2D 3D TSV
US10875854	35	34		Triazolopyridines	Hoffmann-La Roche Inc.	07/25/21	2D 3D TSV
US10870623	23	23		Trifluoromethylpropanamide derivatives as HTRA1 inhibitors	Hoffmann-La Roche Inc.	07/25/21	2D 3D TSV
US10865384	119	47	HGNC:2453 HGNC:2452 HGNC:6876	2,4,5-tri-substituted azole-based casein kinase 1 inhibitors as inducers for cardiomyogenesis	Agency for Science, Technology and Research; National University of Singapore	07/18/21	2D 3D TSV
US10865208	231	229	HGNC:16935	ATG7 inhibitors and the uses thereof	MILLENNIUM PHARMACEUTICALS, INC.	07/18/21	2D 3D TSV
US10864248	3	3		Dab2 inhibitors for the prevention and treatment of cystic fibrosis	TRUSTEES OF DARTMOUTH COLLEGE	07/18/21	2D 3D TSV
US10865182	17	17		Difluoroketamide derivatives as HtrA1 inhibitors	Hoffmann-La Roche Inc.	07/18/21	2D 3D TSV
US10864201	57	57		Heteroaromatic compounds as Vanin inhibitors	Boehringer Ingelheim International GmbH	07/18/21	2D 3D TSV
US10865206	15	15	HGNC:1778	Inhibitors of cyclin-dependent kinase 7 (CDK7)	Syros Pharmaceuticals, Inc.	07/18/21	2D 3D TSV
US10864202	75	75	HGNC:29079	Inhibitors of lysine specific demethylase-1	Celgene Quanticel Research, Inc.	07/18/21	2D 3D TSV
US10865186	25	12	HGNC:8154 HGNC:8156	Opioid agonists and uses thereof	Nektar Therapeutics	07/18/21	2D 3D TSV
US10865195	7	7	HGNC:10548	Pet imaging agents	Novartis AG	07/18/21	2D 3D TSV
US10851050	39	39		Biaryl urea derivative or salt thereof and preparation process and use for the same	FUDAN UNIVERSITY	07/13/21	2D 3D TSV
US10849881	117	116	HGNC:10548	Octahydro-cyclobuta[1,2-c;3,4-c′]dipyrrol-2-yl	Hoffmann-La Roche Inc.	07/13/21	2D 3D TSV
US10849901	159	140		Arf6 inhibitors and methods of synthesis and use thereof	Navigen, Inc.; The University of Utah Research Foundation	07/12/21	2D 3D TSV
US10851083	186	185		Benzoimidazoles as prolyl hydroxylase inhibitors	Janssen Pharmaceutica NV	07/12/21	2D 3D TSV
US10849883	380	377	HGNC:2771	Benzopyrazole compounds and analogues thereof	BioCryst Pharmaceuticals, Inc.	07/12/21	2D 3D TSV
US10851091	62	21	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Benzoxazepin oxazolidinone compounds and methods of use	Genentech, Inc.	07/12/21	2D 3D TSV
US10851116	188	43	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Bicyclic amines as novel JAK kinase inhibitors	LEO Pharma A/S	07/12/21	2D 3D TSV
US10851105	96	12	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	07/12/21	2D 3D TSV
US10849982	64	64	HGNC:2717	C3-carbon linked glutarimide degronimers for target protein degradation	C4 Therapeutics, Inc.	07/12/21	2D 3D TSV
US10851110	95	92		Heterocyclic inhibitors of PTPN11	BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM	07/12/21	2D 3D TSV
US10851102	162	52	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Imidazole and triazole containing bicyclic compounds as JAK inhibitors	Theravance Biopharma R&D IP, LLC	07/12/21	2D 3D TSV
US10851089	32	30	HGNC:7158	Matrix metalloproteinase (MMP) inhibitors and methods of use thereof	Foresee Pharmaceuticals Co., Ltd.	07/12/21	2D 3D TSV
US10851080	31	31	HGNC:8031	Methods of treatment using pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds	Array Biopharma Inc.	07/12/21	2D 3D TSV
US10851092	6	3	HGNC:9967	Pyridine compound	Daiichi Sankyo Company, Limited	07/12/21	2D 3D TSV
US10851082	434	227	HGNC:7110 HGNC:7111	Substituted aromatic n-heterocyclic compounds as inhibitors of mitogen-activated protein kinase interacting kinase 1 (MNK1) and 2 (MNK2)	Northwestern University	07/12/21	2D 3D TSV
US10851108	7	7	HGNC:6255	Substituted bicyclic heterocyclic compounds	Bristol-Myers Squibb Company	07/12/21	2D 3D TSV
US10849898	122	118	HGNC:29079	Treatment of relapsed and/or refractory solid tumors and non-Hodgkin's lymphomas	CELGENE QUANTICEL RESEARCH, INC.	07/12/21	2D 3D TSV
US10858342	226	112	HGNC:2592 HGNC:2591	Bicyclic imidazole derivatives useful for the treatment of renal diseases, cardiovascular diseases and fibrotic diseases	Boehringer Ingelheim International GmbH	07/11/21	2D 3D TSV
US10857082	27	26		Diarylalkanes as potent inhibitors of binuclear enzymes	Unigen, Inc.	07/11/21	2D 3D TSV
US10858323	12	3	HGNC:4852 HGNC:14064 HGNC:4854 HGNC:4853	HDAC inhibitors for the treatment of diabetic peripheral neuropathy	REGENACY PHARMACEUTICALS, LLC	07/11/21	2D 3D TSV
US10858359	6	6	HGNC:9644	Heterocyclic ring derivatives useful as SHP2 inhibitors	JACOBIO PHARMACEUTICALS CO., LTD.	07/11/21	2D 3D TSV
US10858373	106	53	HGNC:17038	Heterocyclic spiro compounds as MAGL inhibitors	Pfizer Inc.	07/11/21	2D 3D TSV
US10858344	20	20	HGNC:3078	Hydantoin containing deoxyuridine triphosphatase inhibitors	CV6 Therapeutics (NI) Limited	07/11/21	2D 3D TSV
US10858364	15	3	HGNC:3432 HGNC:3430 HGNC:1079 HGNC:1057 HGNC:1133 HGNC:6193 HGNC:6171 HGNC:11719 HGNC:12434 HGNC:3236	Imidazopyrazine inhibitors of Bruton's tyrosine kinase	Acerta Pharma B.V.	07/11/21	2D 3D TSV
US10858362	311	111	HGNC:8775 HGNC:8774 HGNC:8776	Imidazopyrazinones as PDE1 inhibitors	H. Lundbeck A/S	07/11/21	2D 3D TSV
US10858355	37	34	HGNC:8978	Inhibitors of phosphatidylinositol 3-kinase gamma	AstraZeneca AB	07/11/21	2D 3D TSV
US10858368	22	22	HGNC:5302	Modulators of the 5-hydroxytryptamine receptor 7 and their method of use	TEMPLE UNIVERSITY—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION; PRAEVENTIX, LLC	07/11/21	2D 3D TSV
US10858326	5	5	HGNC:17734	Oxazoline pseudodimers, pharmaceutical compositions and the use thereof	PURDUE PHARMA L.P.	07/11/21	2D 3D TSV
US10858356	80	80	HGNC:4324	Pyrazolopyridine derivative having GLP-1 receptor agonist effect	Chugai Seiyaku Kabushiki Kaisha	07/11/21	2D 3D TSV
US10858316	146	98	HGNC:6943	Small molecule inhibitors of the MCL-1 oncoprotein and uses thereof	UNIVERSITY OF MARYLAND, BALTIMORE	07/11/21	2D 3D TSV
US10858365	518	119	HGNC:268 HGNC:262 HGNC:263 HGNC:264	Triazolo-pyrimidine compounds and uses thereof	TBA	07/11/21	2D 3D TSV
US10858366	71	41		Tricyclic compounds useful to treat orthomyxovirus infections	Novartis AG	07/11/21	2D 3D TSV
US10844038	134	16	HGNC:11283 HGNC:8980 HGNC:8979 HGNC:6877 HGNC:8978 HGNC:6735 HGNC:4037 HGNC:6871 HGNC:3942 HGNC:8977 HGNC:9967 HGNC:3765 HGNC:6171 HGNC:11393 HGNC:12841 HGNC:9617 HGNC:3432 HGNC:6844 HGNC:4840 HGNC:3697 HGNC:6845 HGNC:1079 HGNC:6846 HGNC:1057 HGNC:1133 HGNC:6847 HGNC:16627 HGNC:1097 HGNC:6342 HGNC:3955 HGNC:6840 HGNC:2444 HGNC:6842 HGNC:6524 HGNC:6843	1,2-dithiolane compounds useful in neuroprotection, autoimmune and cancer diseases and conditions	SABILA BIOSCIENCES LLC	07/06/21	2D 3D TSV
US10844056	73	63	HGNC:5253	Fused amino pyridine as HSP90 inhibitors	Curis, Inc.	07/06/21	2D 3D TSV
US10844067	255	86	HGNC:6307 HGNC:9967	Heterocyclic compounds as RET kinase inhibitors	Cancer Research Technology Limited	07/06/21	2D 3D TSV
US10842803	100	100	HGNC:11491	Imidazopyridines Syk inhibitors	KRONOS BIO, INC.	07/06/21	2D 3D TSV
US10844057	52	13	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Process for preparing JAK inhibitors and intermediates thereof	Theravance Biopharma R&D IP, LLC	07/06/21	2D 3D TSV
US10844062	94	92	HGNC:6307	Pyridine derivative inhibiting RAF kinase and vascular endothelial growth factor receptor, method for preparing same, pharmaceutical composition containing same, and use thereof	Incheon University Industry Academic Cooperation Foundation; Samjin Pharmaceutical Co., Ltd.; Bamichem Co., Ltd.	07/06/21	2D 3D TSV
US10844069	438	146	HGNC:7027 HGNC:12446	Pyrrolotriazine compounds as TAM inhibitors	Incyte Corporation	07/06/21	2D 3D TSV
US10842799	110	107	HGNC:6871	Serine/threonine kinase inhibitors	GENENTECH, INC.	07/06/21	2D 3D TSV
US10844032	286	271	HGNC:990	Substituted benzofuran, benzothiophene and indole Mcl-1 inhibitors	Vanderbilt University	07/06/21	2D 3D TSV
US10844077	44	22	HGNC:4840 HGNC:1133	Thiazolyl-containing compounds for treating proliferative diseases	Dana-Farber Cancer Institute, Inc.	07/06/21	2D 3D TSV
US10844044	364	359	HGNC:12757	WDR5 inhibitors and modulators	Vanderbilt University	07/06/21	2D 3D TSV
US10836763	48	12	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	5 to 7 membered heterocyclic amides as JAK inhibitors	Theravance Biopharma R&D IP, LLC	06/30/21	2D 3D TSV
US10836764	164	55	HGNC:5295 HGNC:5294	5-HT2C receptor agonists and compositions and methods of use	Arena Pharmaceuticals, Inc.	06/30/21	2D 3D TSV
US10836773	6	6	HGNC:7056	6-fluoro-2-methylbenzo[d]thiazol-5-yl compounds	Eli Lilly and Company	06/30/21	2D 3D TSV
US10836758	75	73	HGNC:10597	Acyl sulfonamide NaV1.7 inhibitors	BRISTOL-MYERS SQUIBB COMPANY	06/30/21	2D 3D TSV
US10829489	98	57	HGNC:8810	Bicyclic heterocyclic derivatives	Merck Patent GmbH	06/30/21	2D 3D TSV
US10836743	110	58	HGNC:6833 HGNC:6834 HGNC:29079	Fluorinated cyclopropylamine compound, preparation method therefor, pharmaceutical composition thereof, and uses thereof	SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES	06/30/21	2D 3D TSV
US10836720	24	13	HGNC:6153	Inhibitors of integrin alpha 5 beta 1 and methods of use	The Regents of the University of California	06/30/21	2D 3D TSV
US10836768	205	47	HGNC:11526 HGNC:6251 HGNC:11527 HGNC:11528	N-acyl-(3-substituted)-(8-substituted)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists	Ogeda SA	06/30/21	2D 3D TSV
US10836742	15	15		N-substituted bicyclic lactams, their preparation and their use as pharmaceuticals	Neomed Institute	06/30/21	2D 3D TSV
US10836741	13	12		Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors	Valo Early Discovery, Inc.	06/30/21	2D 3D TSV
US10836728	22	11	HGNC:711 HGNC:8156	Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same	Mebias Discovery, Inc.	06/30/21	2D 3D TSV
US10836769	56	55		Substituted pyrrolizine compounds and uses thereof	GILEAD SCIENCES, INC.	06/30/21	2D 3D TSV
US10835536	52	50	HGNC:3689	Therapeutic agent for FGFR inhibitor-resistant cancer	Taiho Pharmaceutical Co., Ltd.	06/30/21	2D 3D TSV
US10829488	46	22		N-(phenylsulfonyl)benzamides and related compounds as bcl-2 inhibitors	THE REGENTS OF THE UNIVERSITY OF MICHIGAN	06/29/21	2D 3D TSV
US10828301	51	51	HGNC:11491	2,4-pyrimidinediamine compounds and their uses	Rigel Pharmceuticals, Inc.	06/28/21	2D 3D TSV
US10829480	296	153	HGNC:8155 HGNC:8156	3-((hetero-)aryl)-alkyl-8-amino-2-oxo-l,3-diaza-spiro-[4.5]-decane derivatives	GRUENENTHAL GMBH	06/28/21	2D 3D TSV
US10829478	698	150	HGNC:7160 HGNC:195 HGNC:7159 HGNC:220 HGNC:221	5-[3-[piperazin-1-yl]-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS 4 and 5 inhibitors for treating e.g. osteoarthritis	GALAPAGOS NV	06/28/21	2D 3D TSV
US10829492	73	50	HGNC:6192 HGNC:8031 HGNC:8032 HGNC:8033	Amino pyrazolopyrimidine compound used as neurotrophic factor tyrosine kinase receptor inhibitor	CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; CENTAURUS BIOPHARMA CO., LTD.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.	06/28/21	2D 3D TSV
US10829446	156	155		Aryl sulfonohydrazides	MONASH UNIVERSITY; The Walter and Eliza Hall Institute of Medical Research	06/28/21	2D 3D TSV
US10829481	189	189		Benzimidazole derivatives as modulators of ROR-gamma	Vitae Pharmaceuticals, LLC	06/28/21	2D 3D TSV
US10829487	150	149		Benzylamino substituted pyridopyrimidinones and derivatives as SOS1 inhibitors	Boehringer Ingelheim International GmbH	06/28/21	2D 3D TSV
US10829493	69	23	HGNC:6342	Compositions and methods for treating KIT- and PDGFRA-mediated diseases	Blueprint Medicines Corporation	06/28/21	2D 3D TSV
US10828299	7	7	HGNC:11491	Crystalline monomesylate salt of 6-(6-aminopyrazin-2-yl)-n-(4-(4-(oxetan-3-yl)piperazin-1-yl)phenyl)imidazo[1,2-a]pyrazin-8-amine	KRONOS BIO, INC.	06/28/21	2D 3D TSV
US10829438	7	7		Neprilysin inhibitors	Theravance Biopharma R&D IP, LLC	06/28/21	2D 3D TSV
US10829500	5	5	HGNC:933	Pyridyl-triazabicycles	Hoffmann-La Roche Inc.	06/28/21	2D 3D TSV
US10829502	125	82	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Pyrimidinones as PI3K inhibitors	Incyte Corporation; Incyte Holdings Corporation	06/28/21	2D 3D TSV
US10829491	22	22	HGNC:1133	Pyrimido[5,4-B]indolizine or pyrimido[5,4-B]pyrrolizine compound, preparation method and use thereof	SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACAD	06/28/21	2D 3D TSV
US10828300	248	244	HGNC:1133	Substituted 2,4-diaminopyrimidines as kinase inhibitors	Celgene CAR LLC	06/28/21	2D 3D TSV
US10829448	121	111		Substituted benzoimidazoles as modulators of ROR-γ	Vitae Pharmaceuticals, LLC	06/28/21	2D 3D TSV
US10829490	71	9	HGNC:1780 HGNC:1771 HGNC:1777 HGNC:1774 HGNC:1773 HGNC:1775	Substituted dihydropyrazino[1 ′,2′:1,5]pyrrolo[2,3-d]pyrimidine-based antiproliferative agents	GI Therapeutics, Inc.	06/28/21	2D 3D TSV
US10828290	327	108	HGNC:19310 HGNC:8987	Thiazolecarboxamides and pyridinecarboxamide compounds useful as pim kinase inhibitors	Incyte Corporation; Incyte Holdings Corporation	06/28/21	2D 3D TSV
US10829496	29	27	HGNC:17967	Thienopyridines and benzothiophenes useful as IRAK4 inhibitors	Bristol-Myers Squibb Company	06/28/21	2D 3D TSV
US10829483	103	103	HGNC:17989	Thiophene, manufacturing method thereof, and pharmaceutical application of same	CSTONE PHARMACEUTICAL (SUZHOU) CO., LTD.; CSTONE PHARMACEUTICALS (SHANGHAI) CO., LTD.; CSTONE PHARMACEUTICALS	06/28/21	2D 3D TSV
US10822352	718	703	HGNC:2771	Aryl, heteroaryl, and heterocyclic compounds for treatment of medical disorders	Achillion Pharmaceuticals, Inc.	06/21/21	2D 3D TSV
US10822319	2	2		Crystal of DPP-IV long-acting inhibitor and salt	CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.; CENTAURUS BIOPHARMA CO., LTD.	06/21/21	2D 3D TSV
US10822334	60	30	HGNC:3430 HGNC:3236	ErbB receptor inhibitors	TBA	06/21/21	2D 3D TSV
US10822348	937	789		Inhibitors of Bruton's tyrosine kinase and methods of their use	Janssen Pharmaceutica NV	06/21/21	2D 3D TSV
US10822345	64	63	HGNC:6221	KV1.3 inhibitors and their medical application	4SC AG	06/21/21	2D 3D TSV
US10822331	4	1	HGNC:882	Processes for preparing ATR inhibitors	VERTEX PHARMACEUTICALS INCORPORATED	06/21/21	2D 3D TSV
US10822341	148	37	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyrazolo[1,5-a]pyrazin-4-yl derivatives	Pfizer Inc.	06/21/21	2D 3D TSV
US10822342	12	12	HGNC:6853	Pyrazolopyrimidine derivatives as NIK inhibitors	Janssen Pharmaceutica NV	06/21/21	2D 3D TSV
US10822338	75	74	HGNC:263	Substituted aminoquinazoline compounds as A2A antagonist	Merck Sharp & Dohme Corp.	06/21/21	2D 3D TSV
US10821115	969	797		Compounds that inhibit Mcl-1 protein	AMGEN INC.	06/20/21	2D 3D TSV
US10815234	116	115		Histone demethylase inhibitors	CELGENE QUANTICEL RESEARCH, INC.	06/14/21	2D 3D TSV
US10815244	10	10	HGNC:3236	Isoidide derivatives and methods of making and using same	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	06/14/21	2D 3D TSV
US10815241	10	10	HGNC:7010	Optically active azabicyclo ring derivative	Sumitomo Dainippon Pharma Co., Ltd.	06/14/21	2D 3D TSV
US10813932	120	31	HGNC:11491 HGNC:11283 HGNC:4617 HGNC:4616 HGNC:20790 HGNC:6874 HGNC:6876	1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl) oxy) napththalen-1-yl) ureas as P38 MAP knase inhibitors	Respivert Limited	06/13/21	2D 3D TSV
US10815215	268	215	HGNC:2867	2,4,5-trisubstituted 1,2,4-triazolones useful as inhibitors of DHODH	BAYER AKTIENGESELLSCHAFT; BAYER PHARMA AKTIENGELLSCHAFT; THE BROAD INSTITUTE, INC.; PRESIDENT AND FELLOWS OF HARVARD COLLEGE; THE GENERAL HOSPITAL CORPORATION	06/13/21	2D 3D TSV
US10815229	1146	325	HGNC:10593 HGNC:10585 HGNC:10596	Benzenesulfonamide compounds and their use as therapeutic agents	Xenon Pharmaceuticals Inc.	06/13/21	2D 3D TSV
US10815213	190	140	HGNC:1133 HGNC:3236	Bruton's tyrosine kinase inhibitors	Pfizer Inc.	06/13/21	2D 3D TSV
US10815208	4	4		Method for preparing 2-hydroxyl-4-(2, 3-disubstituted benzyloxy)-5-substituted benzaldehyde derivative	Institute of Materia Medica, Chinese Academy of Medical Sciences; Tianjin Chase Sun Pharmaceutical Co., LTD	06/13/21	2D 3D TSV
US10815206	95	90		RIP1 inhibitory compounds and methods for making and using the same	Rigel Pharmaceuticals, Inc.	06/13/21	2D 3D TSV
US10813930	107	107	HGNC:3690	Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3	Incyte Corporation; Incyte Holdings Corporation	06/13/21	2D 3D TSV
US10813942	17	17	HGNC:742	Substituted-6,8-dioxabicyclo[3.2.1]octane-2,3-diol compounds as targeting agents of ASGPR	Pfizer Inc.	06/13/21	2D 3D TSV
US10806718	605	192	HGNC:8775 HGNC:8774 HGNC:8776	1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors	H. Lundbeck A/S	06/11/21	2D 3D TSV
US10807988	693	382	HGNC:8155 HGNC:8156	3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives	Grünenthal GmbH	06/11/21	2D 3D TSV
US10807989	571	289	HGNC:8155 HGNC:8156	3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives	GRÜNENTHAL GMBH	06/11/21	2D 3D TSV
US10807982	105	104	HGNC:13575	Bromodomain inhibitors	Celgene Quanticel Research, Inc.	06/11/21	2D 3D TSV
US10806724	59	59	HGNC:4594	Chromane, isochromane and dihydroisobenzofuran derivatives as mGluR2-negative allosteric modulators, compositions, and their use	Merck Sharp & Dohme Corp.	06/11/21	2D 3D TSV
US10807985	169	124		Compositions useful for treating disorders related to kit	Blueprint Medicines Corporation	06/11/21	2D 3D TSV
US10807952	101	101	HGNC:2771	Compounds for treatment of immune inflammatory disorders	Achillion Pharmaceuticals, Inc.	06/11/21	2D 3D TSV
US10807993	63	51	HGNC:6251	Dihydrochromene derivatives	Sumitomo Dainippon Pharma Co., Ltd.	06/11/21	2D 3D TSV
US10807980	220	156		Dihydropyrrolopyridine inhibitors of ROR-gamma	Vitae Pharmaceuticals, LLC	06/11/21	2D 3D TSV
US10807986	522	200	HGNC:9967	Fused pyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd.	06/11/21	2D 3D TSV
US10807944	144	42	HGNC:4852 HGNC:14064 HGNC:13315 HGNC:4854 HGNC:4853	HDAC inhibitor compounds and methods of treatment	University of Florida Research Foundation, Inc.; The Scripps Research Institute	06/11/21	2D 3D TSV
US10807994	99	97	HGNC:12761	Heterocyclic compounds and uses thereof	NUVATION BIO INC.	06/11/21	2D 3D TSV
US10807966	27	16	HGNC:10251 HGNC:10252	Heterocyclic compounds as kinase inhibitors	Translational Drug Development, LLC	06/11/21	2D 3D TSV
US10807956	210	101	HGNC:9886 HGNC:17071 HGNC:18039	Histone demethylase inhibitors	CELGENE QUANTICEL RESEARCH, INC.	06/11/21	2D 3D TSV
US10806785	205	191		Immunomodulator compounds and methods of use	Incyte Corporation	06/11/21	2D 3D TSV
US10807974	309	161	HGNC:6833 HGNC:6834 HGNC:80 HGNC:6666	Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer	The Institute of Cancer Research: Royal Cancer Hospital	06/11/21	2D 3D TSV
US10806794	28	28		Protease inhibitors having enhanced features	Nektar Therapeutics	06/11/21	2D 3D TSV
US10807971	68	17	HGNC:16672 HGNC:3009	Pyrrolidinone compounds	Eli Lilly and Company	06/11/21	2D 3D TSV
US10806720	76	51	HGNC:644	Selective androgen receptor degrader (SARD) ligands and methods of use thereof	University of Tennessee Research Foundation	06/11/21	2D 3D TSV
US10807991	122	42	HGNC:3167 HGNC:3165 HGNC:14299	Spiro-cyclic amine derivatives as S1P modulators	AbbVie B.V.; AbbVie, Inc.	06/11/21	2D 3D TSV
US10807959	266	260	HGNC:12757	WDR5-MLL1 inhibitors and modulators	Vanderbilt University	06/11/21	2D 3D TSV
US10800755	217	38	HGNC:3023 HGNC:5286 HGNC:6251	2,6-disubstituted pyridine derivative	SUMITOMO DAINIPPON PHARMA CO., LTD.	06/01/21	2D 3D TSV
US10800739	37	20	HGNC:270 HGNC:272	4-carboxamido-isoindolinone derivatives as selective PARP-1 inhibitors	NERVIANO MEDICAL SCIENCES S.R.L.	06/01/21	2D 3D TSV
US10799507	607	155	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	5-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-5-azaspiro[2.5]octane-8-carboxylic acid derivatives as novel JAK kinase inhibitors	Leo Pharma A/S	06/01/21	2D 3D TSV
US10800725	60	20		Arylpropionyl-triketone antibacterial agents	TBA	06/01/21	2D 3D TSV
US10800778	120	40		Beta-lactamase inhibitor compounds	Entasis Therapeutics Limited	06/01/21	2D 3D TSV
US10800786	33	32	HGNC:10548	Bicyclic compounds as ATX inhibitors	Hoffman-La Roche Inc.	06/01/21	2D 3D TSV
US10800783	433	218	HGNC:1771	CDK2/4/6 inhibitors	Pfizer Inc.	06/01/21	2D 3D TSV
US10800761	113	105	HGNC:6863	Carboxamide compounds and uses thereof	Incyte Corporation	06/01/21	2D 3D TSV
US10799494	22	22		Combination of respiratory electron transport chain inhibitors with a cytochrome bd inhibitor	TBA	06/01/21	2D 3D TSV
US10799605	13	7	HGNC:8039	Conjugate comprising a neurotensin receptor ligand and use thereof	3B Pharmaceuticals GMBH	06/01/21	2D 3D TSV
US10800776	45	25	HGNC:4594 HGNC:6251	Fluorine-containing triazolopyridine, and manufacturing method, pharmaceutical composition, and application thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	06/01/21	2D 3D TSV
US10800779	138	138	HGNC:29079	Heterocyclic compounds as LSD1 inhibitors	Incyte Corporation	06/01/21	2D 3D TSV
US10800768	271	266		Heterocyclic compounds as immunomodulators	Incyte Corporation	06/01/21	2D 3D TSV
US10800769	265	122	HGNC:1925	Heterocyclic inhibitors of ATR kinase	Board of Regents, The University of Texas System; ChemPartner Corporation	06/01/21	2D 3D TSV
US10800774	64	32	HGNC:1925	Heterocyclic inhibitors of ATR kinase	Board of Regents, The University of Texas System; ChemPartner Corporation	06/01/21	2D 3D TSV
US10800804	26	12	HGNC:6561 HGNC:6563	Hybrid galactoside inhibitor of galectins	TBA	06/01/21	2D 3D TSV
US10800744	41	41	HGNC:3827	Imidazole derivatives as formyl peptide receptor modulators	ALLERGAN, INC.	06/01/21	2D 3D TSV
US10800765	63	62	HGNC:4502	Indole derivative used as CRTH2 inhibitor	CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.	06/01/21	2D 3D TSV
US10800792	937	912	HGNC:1133	Inhibitors of Bruton's tyrosine kinase and method of their use	Janssen Pharmaceutica NV	06/01/21	2D 3D TSV
US10800757	96	94	HGNC:12338	Inhibitors of TRPC6	Boehringer Ingelheim International GmbH; Hydra Biosciences, LLC	06/01/21	2D 3D TSV
USRE48253	9	9	HGNC:12576	Methotrexate adjuvants to reduce toxicity and methods for using the same	Tosk, Inc.	06/01/21	2D 3D TSV
US10800784	246	123	HGNC:8809 HGNC:8810	Nitrogen-containing heterocyclic amide compound and pharmaceutical use thereof	JAPAN TOBACCO INC.	06/01/21	2D 3D TSV
US10800746	22	11	HGNC:897 HGNC:895	Oxoalkyl-substituted phenyltriazole derivatives and uses thereof	BAYER PHARMA AKTIENGESELLSCHAFT	06/01/21	2D 3D TSV
US10800775	14	7	HGNC:6190	Pyrazolyl pyrrolo[2,3-b]pyrmidine-5-carboxylate analogs and methods of making the same	ACLARIS THERAPEUTICS, INC.	06/01/21	2D 3D TSV
US10800764	23	6		Substituted pyridine derivatives useful as C-FMS kinase inhibitors	Janssen Pharmaceutica NV	06/01/21	2D 3D TSV
US10800785	97	85	HGNC:1133	Substituted pyrrolo[2,3-d]pyridazin-4-ones and pyrazolo[3,4-d]pyridazin-4-ones as protein kinase inhibitors	Shanghai Fochon Pharmaceutical Co., Ltd.; Fochon Pharmaceuticals, Ltd.	06/01/21	2D 3D TSV
US10800753	7	7	HGNC:23	Tetrahydrothiophene-based GABA aminotransferase inactivators and analogs thereof for treating neurological disorders	Northwestern University	06/01/21	2D 3D TSV
US10800767	82	36	HGNC:11799 HGNC:11796	Thyroid hormone receptor beta agonist compounds	Terns, Inc.	06/01/21	2D 3D TSV
US10799518	188	179	HGNC:3827	Use of agonists of formyl peptide receptor 2 for treating dermatological diseases	ALLERGAN, INC.	06/01/21	2D 3D TSV
US10793561	2	2	HGNC:262	1,8-naphthyridinone compounds and uses thereof	NUVATION BIO INC.	05/14/21	2D 3D TSV
US10793528	143	73	HGNC:8156	3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives	GRÜNENTHAL GMBH	05/14/21	2D 3D TSV
US10793556	178	34	HGNC:8155 HGNC:8156	8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives	GRUENENTHAL GMBH	05/14/21	2D 3D TSV
US10793564	145	144	HGNC:6161	Amino acid compounds and methods of use	PLIANT THERAPEUTICS, INC.	05/14/21	2D 3D TSV
US10793552	3	3	HGNC:550	Amino pyrimidine ssao inhibitors	ELI LILLY AND COMPANY	05/14/21	2D 3D TSV
US10793582	85	84	HGNC:17929	Bicyclic heterocyclic compound	MITSUBISHI TANABE PHARMA CORPORATION	05/14/21	2D 3D TSV
US10793567	30	15	HGNC:4852 HGNC:4853	Bicyclic inhibitors of histone deacetylase	Rodin Therapeutics, Inc.	05/14/21	2D 3D TSV
US10793579	370	361	HGNC:17967	Bicyclic-fused heteroaryl or aryl compounds	Pfizer Inc.	05/14/21	2D 3D TSV
US10793566	134	123	HGNC:6735 HGNC:1057 HGNC:1133 HGNC:3236 HGNC:6524	Bruton's tyrosine kinase inhibitors	ZIBO BIOPOLAR CHANGSHENG PHARMACEUTICAL CO. LTD.; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES	05/14/21	2D 3D TSV
US10793576	128	126	HGNC:1133	Compound used as Bruton's tyrosine kinase inhibitor and preparation method and application thereof	CHENGDU BRILLIANT PHARMACEUTICAL CO., LTD.; CHENGDU HIGHBRED PHARMACEUTICAL CO., LTD.	05/14/21	2D 3D TSV
US10793563	532	502	HGNC:19687	GCN2 inhibitors and uses thereof	MERCK PATENT GMBH; VERTEX PHARMACEUTICALS INCORPORATED	05/14/21	2D 3D TSV
US10793514	38	19	HGNC:10943	Glutamine transport inhibitors and methods for treating cancer	Vanderbilt University	05/14/21	2D 3D TSV
US10793565	4	4		Heterocyclic compounds as immunomodulators	Incyte Corporation	05/14/21	2D 3D TSV
US10793535	51	45		Heterocyclic glutaminase inhibitors	Calithera Biosciences, Inc.	05/14/21	2D 3D TSV
US10793568	340	336	HGNC:7967	Hormone receptor modulators for treating metabolic conditions and disorders	ARDELYX, INC.	05/14/21	2D 3D TSV
US10793575	89	59	HGNC:1133	Oxoisoquinoline derivatives	CARNA BIOSCIENCES, INC.	05/14/21	2D 3D TSV
US10792283	7	7	HGNC:8977	Quinoline analogs as phosphatidylinositol 3-kinase inhibitors	HANGZHOU ZHENGXIANG PHARMACEUTICALS CO., LTD.	05/14/21	2D 3D TSV
US10793545	22	22	HGNC:17967	Substituted indazoles, methods for the production thereof, pharmaceutical preparations that contain said new substituted indazoles, and use of said new substituted indazoles to produce drugs	Bayer Pharma Aktiengesellschaft	05/14/21	2D 3D TSV
US10793591	16	15		Substituted nucleosides, nucleotides and analogs thereof	Janssen BioPharma, Inc.	05/14/21	2D 3D TSV
US10793580	310	310	HGNC:8783	Substituted pyrazoloazepin-8-ones and their use as phosphodiesterase inhibitors	LEO Pharma A/S	05/14/21	2D 3D TSV
US10793529	4	4	HGNC:9602	Substituted pyridazines and 1,2,4-triazines as prostacyclin receptor modulators	ARENA PHARMACEUTICALS, INC.	05/14/21	2D 3D TSV
US10793549	63	59		Sulfuryl-substituted benzoheterocyclic derivative, preparation method and medical use thereof	SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD.; YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD.	05/14/21	2D 3D TSV
US10793574	218	217		TYK2 inhibitors and uses thereof	Nimbus Lakshmi, Inc.	05/14/21	2D 3D TSV
US10787452	579	555	HGNC:882	Compounds useful as inhibitors of ATR kinase	VERTEX PHARMACEUTICALS INCORPORATED	05/11/21	2D 3D TSV
US10787435	57	56	HGNC:6857	ASK1 inhibitor and preparation method and use thereof	Fuijan Cosunter Pharmaceutical Co. Ltd.	05/09/21	2D 3D TSV
US10787434	9	9	HGNC:10894	Benzopiperdine derivatives and their use in the treatment of cancer and hemoglobinopathies	CTXT PTY, LTD	05/09/21	2D 3D TSV
US10787459	13	3	HGNC:10548	Bicyclic compounds as ATX inhibitors	Hoffmann-La Roche Inc.	05/09/21	2D 3D TSV
US10787419	92	90		Cannabinoid receptor mediating iminopyrazole compounds	The United States of America, as represented by the Secretary, Department of Health and Human Services	05/09/21	2D 3D TSV
US10787457	78	78	HGNC:9967	Fused pyrimidine compound or salt thereof	Taiho Pharmaceutical Co., Ltd.	05/09/21	2D 3D TSV
US10787436	82	40	HGNC:1780 HGNC:1771 HGNC:1778 HGNC:6881 HGNC:1722 HGNC:6112 HGNC:6850 HGNC:1779 HGNC:1774 HGNC:6886	Inhibitors of cyclin-dependent kinase 7 (CDK7)	Dana-Farber Cancer Institute, Inc.	05/09/21	2D 3D TSV
US10787453	2	2	HGNC:9922	Octahydropyrrolopyrroles their preparation and use	The Trustees of Columbia University in the City of New York	05/09/21	2D 3D TSV
US10787472	23	23	HGNC:10582	Prodrugs of pyridone amides useful as modulators of sodium channels	Vertex Pharmaceuticals Incorporated	05/09/21	2D 3D TSV
US10787450	255	253	HGNC:10252	Spiro-fused cyclic ureas as inhibitors of rock	Bristol-Myers Squibb Company	05/09/21	2D 3D TSV
US10787438	40	18		Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors	Pfizer Inc.	05/09/21	2D 3D TSV
US10787425	105	105	HGNC:5154	Thiazolidinedione derivative and use thereof	INDUSTRY-ACADEMIC COOPERATION FOUNDATION CHOSUN UNIVERSITY	05/09/21	2D 3D TSV
US10781209	196	93	HGNC:13575	1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins	Incyte Corporation	05/03/21	2D 3D TSV
US10781212	4	2		2,6-diamino pyridine compounds	Eli Lilly and Company	05/03/21	2D 3D TSV
US10781180	4	4		3-phenyl-pyrazole derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto	Arena Pharmaceuticals, Inc.	05/03/21	2D 3D TSV
US10781202	10	10	HGNC:8781	Azetidinyloxyphenylpyrrolidine compounds	Eli Lilly and Company	05/03/21	2D 3D TSV
US10781182	12	6	HGNC:7463	Compounds, process for obtaining the compounds, pharmaceutical composition, use of the compounds and method for treating psychiatric disorders and/or sleep disorders	ACHÉ LABORATÓRIOS FARMACÊUTICOS S.A.	05/03/21	2D 3D TSV
US10781185	149	108	HGNC:17270	Heterocyclic compounds for the inhibition of PASK	BioEnergenix LLC	05/03/21	2D 3D TSV
US10781181	216	108	HGNC:6371 HGNC:6357	N-((het) arylmethyl)-heteroaryl-carboxamides compounds as plasma kallikrein inhibitors	KALVISTA PHARMACEUTICALS LIMITED	05/03/21	2D 3D TSV
US10781211	677	260	HGNC:17038	Spirocycle compounds and methods of making and using same	LUNDBECK LA JOLLA RESEARCH CENTER, INC.	05/03/21	2D 3D TSV
US10781204	378	163	HGNC:6192 HGNC:12440	TYK2 inhibitors and uses thereof	Nimbus Lakshmi, Inc.	05/03/21	2D 3D TSV
US10781200	140	137	HGNC:6371	Therapeutic inhibitory compounds	ATTUNE PHARMACEUTICALS, INC.	05/03/21	2D 3D TSV
US10780095	30	25	HGNC:15836	Compositions and methods for treating disorders of circadian and diurnal rhythms using prokineticin 2 agonists and antagonists	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA	05/02/21	2D 3D TSV
US10780092	156	151	HGNC:4685	Fused pyrazine derivatives useful as soluble guanylate cyclase stimulators	Merck Sharp & Dohme Corp.	05/02/21	2D 3D TSV
US10780090	537	352	HGNC:30660	Heteroaryl compounds useful as inhibitors of SUMO activating enzyme	Millennium Pharmaceuticals, Inc.	05/02/21	2D 3D TSV
US10780082	18	3	HGNC:427	Macrocycle and composition comprising thereof	Shenzhen TargetRx, Inc.	05/02/21	2D 3D TSV
US10780078	21	7	HGNC:8153 HGNC:8155 HGNC:8156	Mu opioid receptor modulators	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; FRIEDRICH-ALEXANDER-UNIVERSITÄT; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY	05/02/21	2D 3D TSV
US10781171	288	287	HGNC:4501	Substituted pyrrolidines as G-protein coupled receptor 43 agonists	Epics Therapeutics	05/02/21	2D 3D TSV
US10766893	768	242	HGNC:8775 HGNC:8774 HGNC:8776	1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors	H. Lundbeck A/S	04/26/21	2D 3D TSV
US10766881	246	83		2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2H)-one compounds as inhibitors of FGFR tyrosine kinases	Array Biopharma Inc.	04/26/21	2D 3D TSV
US10766883	18	9	HGNC:6190 HGNC:6192	Aminopyrazoles as janus kinase inhibitors	Merck Sharp & Dohme Corp.	04/26/21	2D 3D TSV
US10766894	52	13	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Aza-indazole compounds for use in tendon and/or ligament injuries	NOVARTIS AG	04/26/21	2D 3D TSV
US10766884	294	137	HGNC:1773	Cyclin dependent kinase inhibitors	Pfizer Inc.	04/26/21	2D 3D TSV
US10766897	213	155	HGNC:6251 HGNC:550	Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors	PROXIMAGEN, LLC	04/26/21	2D 3D TSV
US10766864	106	106	HGNC:8156	Morphinan derivatives for the treatment of neuropathic pain	Nektar Therapeutics	04/26/21	2D 3D TSV
US10766903	245	243	HGNC:12630	Piperidine derivatives as inhibitors of ubiquitin specific protease 7	ALMAC DISCOVERY LIMITED	04/26/21	2D 3D TSV
US10766858	25	19	HGNC:10597	Substituted benzamides and methods of use thereof	GENENTECH, INC.; XENON PHARMACEUTICALS INC.	04/26/21	2D 3D TSV
US10766878	63	33	HGNC:497	Sulfonylcycloalkyl carboxamide compounds	Genentech, Inc.	04/26/21	2D 3D TSV
US10765676	43	43	HGNC:8031	Trk-inhibiting compound	ONO PHARMACEUTICAL CO., LTD.	04/26/21	2D 3D TSV
US10766902	96	96	HGNC:12761	Wee-1 inhibiting pyrazolopyrimidinone compounds	ALMAC DISCOVERY LIMITED	04/26/21	2D 3D TSV
US10774065	22	22	HGNC:9644	1-pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine derivatives and compositions thereof for inhibiting the activity of SHP2	NOVARTIS AG	04/25/21	2D 3D TSV
US10772893	488	432		2-(morpholin-4-yl)-1,7-naphthyridines	BAYER PHARMA AKTIENGESELLSCHAFT	04/25/21	2D 3D TSV
US10774070	79	39	HGNC:9967	2-(pyridin-3-yl)-pyrimidine derivatives as RET inhibitors	BLUEPRINT MEDICINES CORPORATION	04/25/21	2D 3D TSV
US10774051	1232	1204	HGNC:8537	6-membered heterocyclic derivatives and pharmaceutical composition comprising the same	SHIONOGI & CO., LTD.	04/25/21	2D 3D TSV
US10774068	200	123	HGNC:11408 HGNC:11406	Composition and methods for inhibiting mammalian sterile 20-like kinase 1	THE SCRIPPS RESEARCH INSTITUTE; UNIVERSITÄT BREMEN	04/25/21	2D 3D TSV
US10774069	4	3	HGNC:6666	Crystalline forms of a lysyl oxidase-like 2 inhibitor and methods of making	PHARMAKEA, INC.	04/25/21	2D 3D TSV
US10774054	16	8	HGNC:7967	FXR (NR1H4) modulating compounds	Gilead Sciences, Inc.	04/25/21	2D 3D TSV
US10774102	106	106	HGNC:6563	Galactoside inhibitor of galectins	Galecto Biotech AB	04/25/21	2D 3D TSV
US10774053	706	352		HIV protease inhibitors	Gilead Sciences, Inc.	04/25/21	2D 3D TSV
US10774052	194	191	HGNC:3691	Heteroaryl compounds and uses thereof	Celgene CAR LLC; Sanofi	04/25/21	2D 3D TSV
US10752635	54	54	HGNC:6863	Indazole compounds and uses thereof	Incyte Corporation	04/25/21	2D 3D TSV
US10774063	26	24	HGNC:10289	Materials and method for inhibiting replication protein A and uses thereof	Indiana University Research and Technology Corporation	04/25/21	2D 3D TSV
US10774085	105	105	HGNC:8031	Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds	ARRAY BIOPHARMA INC.	04/25/21	2D 3D TSV
US10774071	762	381		PD-1/PD-L1 inhibitors	Gilead Sciences, Inc.	04/25/21	2D 3D TSV
US10774056	197	71	HGNC:4852 HGNC:6251 HGNC:4854 HGNC:4853	Substituted piperazines as selective HDAC1,2 inhibitors	REGENACY PHARMACEUTICALS, INC.	04/25/21	2D 3D TSV
US10774092	345	343	HGNC:12558	ULK1 inhibitors and methods using same	SALK INSTITUTE FOR BIOLOGICAL STUDIES; SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE; YALE UNIVERSITY	04/25/21	2D 3D TSV
US10759805	43	43	HGNC:6871	Compounds that are ERK inhibitors	Merck Sharp & Dohme Corp.	04/19/21	2D 3D TSV
US10759799	40	20	HGNC:4617 HGNC:3091	Indazole containing macrocycles and therapeutic uses thereof	Samumed, LLC	04/19/21	2D 3D TSV
US10759813	222	220	HGNC:7154	Neprilysin inhibitors	Theravance Biopharma R&D IP, LLC	04/19/21	2D 3D TSV
US10759812	26	15	HGNC:85 HGNC:84	Thienopyrimidine derivative and use thereof in medicine	Sunshine Lake Pharma Co., Ltd.	04/19/21	2D 3D TSV
US10759793	318	106		2-(pyrazolopyridin-3-yl)pyrimidine derivatives as JAK inhibitors	Almirall, S.A.	04/18/21	2D 3D TSV
US10759794	172	77	HGNC:6283 HGNC:6278	2-phenyl-3-(piperazinomethyl)imidazo[1,2-A]pyridine derivatives as blockers of task-1 and task-2 channels, for the treatment of sleep-related breathing disorders	BAYER PHARMA AKTIENGESELLSCHAFT	04/18/21	2D 3D TSV
US10759787	43	33		Benzofuran derivative, preparation method thereof and use thereof in medicine	Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd.	04/18/21	2D 3D TSV
US10759796	139	138		CXCR4 inhibitors and uses thereof	X4 PHARMACEUTICALS, INC.	04/18/21	2D 3D TSV
US10759792	26	26		CaMKII inhibitors and uses thereof	The Johns Hopkins University	04/18/21	2D 3D TSV
US10759777	138	138	HGNC:8846	Carbazole-containing amides, carbamates, and ureas as cryptochrome modulators	Synchronicity Pharma, Inc.	04/18/21	2D 3D TSV
US10758530	28	20	HGNC:10435 HGNC:10431 HGNC:10430 HGNC:10432	Carboxamide derivatives useful as rsk inhibitors	PHOENIX MOLECULAR DESIGNS	04/18/21	2D 3D TSV
US10759766	58	32	HGNC:6307	Certain chemical entities, compositions, and methods	NEUPHARMA, INC.	04/18/21	2D 3D TSV
US10759769	46	46	HGNC:12524	Glucosylceramide synthase inhibitors for the treatment of diseases	TBA	04/18/21	2D 3D TSV
US10759791	104	24	HGNC:7872	Mammalian and bacterial nitric oxide synthase inhibitors	Northwestern University	04/18/21	2D 3D TSV
US10759788	6	2	HGNC:6251 HGNC:6255	Pharmaceutical uses of pyridine carboxamide derivatives	JIANGSU HENGRUI MEDICINE CO., LTD.; SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.	04/18/21	2D 3D TSV
US10758542	530	232	HGNC:8031 HGNC:12440	Substituted pyrazolo[l,5-a]pyrimidine compounds as Trk kinase inhibitors	Array BioPharma Inc.	04/18/21	2D 3D TSV
US10758539	7	7	HGNC:6307	Therapeutic compounds and uses thereof	Kala Pharmaceuticals, Inc.	04/18/21	2D 3D TSV
US10745383	8	8		1,3,5-triazine derivative and method of using same	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.; Lianyungang Runzhong Pharmaceutical Co., Ltd.; Centaurus Biopharma Co., Ltd.	04/13/21	2D 3D TSV
US10744128	140	66	HGNC:4617 HGNC:3091	6-(5-membered heteroaryl)isoquinolin-3-yl-(5-membered heteroaryl) carboxamides and preparation and use thereof	Samumed, LLC	04/13/21	2D 3D TSV
US10744125	24	6	HGNC:268 HGNC:262 HGNC:263 HGNC:264	Adenosine A3 receptor modulators	Palobiofarma, S.L.	04/13/21	2D 3D TSV
US10745392	57	19	HGNC:10593 HGNC:10585 HGNC:10596	Benzenesulfonamide compounds and their use as therapeutic agents	Xenon Pharmaceuticals Inc.	04/13/21	2D 3D TSV
US10745401	582	190	HGNC:3023 HGNC:5286	Condensed lactam derivative	SUMITOMO DAINIPPON PHARMA CO., LTD.	04/13/21	2D 3D TSV
US10745399	334	57	HGNC:8978 HGNC:795 HGNC:8975 HGNC:3942 HGNC:8977 HGNC:8976	Imidazolonylquinolines and the use thereof as ATM kinase inhibitors	Merck Patent GmbH	04/13/21	2D 3D TSV
US10745388	16	16	HGNC:6863	Indazole compounds and uses thereof	Incyte Corporation	04/13/21	2D 3D TSV
US10745380	2	2	HGNC:10894	Pyridine derivatives and their use in the treatment of cancer and hemoglobinopathies	CTXT PTY LTD	04/13/21	2D 3D TSV
US10745410	18	18		Substituted [5,6]cyclic-4(3H)-pyrimidinones as anticancer agents	ZENJI RESEARCH LABORATORIES	04/13/21	2D 3D TSV
US10745364	424	420		Tetrahydronaphthyridine, benzoxazine, aza-benzoxazine and related bicyclic compounds for inhibition of RORgamma activity and the treatment of disease	Lycera Corporation; Merck Sharp & Dohme Corp.	04/13/21	2D 3D TSV
US10745420	101	96		Tetrahydropyrido[4,3-d]pyrimidine inhibitors of ATR kinase	Board of Regents, The University of Texas System; ChemPartner Corporation	04/13/21	2D 3D TSV
US10744104	41	40	HGNC:7154	Neprilysin inhibitors	Theravance Biopharma R&D IP, LLC	04/12/21	2D 3D TSV
US10744117	5	5	HGNC:9236	PPARG modulators for the treatment of osteoporosis	The Scripps Research Institute; The University of Toledo	04/12/21	2D 3D TSV
US10752581	86	75	HGNC:429 HGNC:433	4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase	Eastern Virginia Medical School; The Regents of the University of California Santa; The United States of America Department of Health; Thomas Jefferson University	04/11/21	2D 3D TSV
US10752632	6	6	HGNC:7056	6-fluoro 2-methylbenzo[d]thiazol-5-yl compounds	Eli Lilly and Company	04/11/21	2D 3D TSV
US10752598	20	20		Aryldiazepine derivatives as RSV inhibitors	Enanta Pharmaceuticals, Inc.	04/11/21	2D 3D TSV
US10752616	136	46	HGNC:9864 HGNC:9866 HGNC:9865	Bicycloheteroaryl-heteroaryl-benzoic acid compounds as retinoic acid receptor beta (RARβ) agonists	King''s College London	04/11/21	2D 3D TSV
US10752604	35	20	HGNC:11037 HGNC:11036	C-glucoside derivative containing fused phenyl ring or pharmaceutically acceptable salt thereof, process for preparing same, and pharmaceutical composition comprising same	Je II Pharmaceutical Co., Ltd.	04/11/21	2D 3D TSV
US10752613	21	15	HGNC:12805 HGNC:17989	Compounds and their use for reducing uric acid levels	Acquist LLC	04/11/21	2D 3D TSV
US10752588	28	27	HGNC:3023	Dopamine D2 receptor ligands	The Broad Institute, Inc.; Massachusetts Institute of Technology	04/11/21	2D 3D TSV
US10752623	196	62	HGNC:10593 HGNC:10585 HGNC:10596	Heteroaryl-substituted sulfonamide compounds and their use as sodium channel inhibitors	Xenon Pharmaceuticals Inc.	04/11/21	2D 3D TSV
US10752631	37	12	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Heterocyclic compounds as FGFR inhibitors	Guangzhou Innocare Pharma Tech Co., Ltd.	04/11/21	2D 3D TSV
US10752626	25	25		Iso-citrate dehydrogenase (IDH) inhibitor	SHANGHAI METON PHARMACEUTICAL CO., LTD	04/11/21	2D 3D TSV
US10752592	113	38	HGNC:8156	Morphan and morphinan analogues, and methods of use	ALKERMES PHARMA IRELAND LIMITED	04/11/21	2D 3D TSV
US10752596	153	152		Nitrogen-containing heteroaryl compound and pharmaceutical use thereof	JAPAN TOBACCO INC.	04/11/21	2D 3D TSV
US10751335	60	28	HGNC:8156	Signaling-biased mu opioid receptor agonists	THE SCRIPPS RESEARCH INSTITUTE	04/11/21	2D 3D TSV
US10752615	526	148	HGNC:1133 HGNC:6171 HGNC:11719 HGNC:12434	Spirocyclic containing compounds and pharmaceutical uses thereof	GB005, Inc.	04/11/21	2D 3D TSV
US10751339	55	14	HGNC:8979 HGNC:8978 HGNC:6251	Substituted aminopyrimidine compounds and methods of use	SUNSHINE LAKE PHARMA CO., LTD.; CALITOR SCIENCES, LLC	04/11/21	2D 3D TSV
US10738015	84	42	HGNC:8155 HGNC:8156	1,3-diaza-spiro-[3.4]-octane derivatives	GRÜNENTHAL GMBH	04/04/21	2D 3D TSV
US10738063	246	64		6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide compounds	Pfizer Inc.	04/04/21	2D 3D TSV
US10738007	130	97	HGNC:10251 HGNC:10252	Amide compounds as kinase inhibitors, compositions and methods of treatment	Translation Drug Development, LLC	04/04/21	2D 3D TSV
USRE48150	34	33	HGNC:6857	Apoptosis signal-regulating kinase inhibitors	Gilead Sciences, Inc.	04/04/21	2D 3D TSV
US10736881	141	96	HGNC:4852 HGNC:13315	Benzimidazole derivatives: preparation and pharmaceutical applications	MEI Pharma, Inc.	04/04/21	2D 3D TSV
US10738053	42	4	HGNC:1373 HGNC:10548	Bicyclic compounds as dual ATX/CA inhibitors	Hoffmann-La Roche Inc.	04/04/21	2D 3D TSV
US10738048	152	37	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	04/04/21	2D 3D TSV
US10738074	43	29		Cyclic di-nucleotide compounds as STING agonists	Merck Sharp & Dohme Corp.	04/04/21	2D 3D TSV
US10738052	205	204	HGNC:7029	Imidazotriaines and imidazopyrimidines as kinase inhibitors	INCYTE HOLDINGS CORPORATION; INCYTE CORPORATION	04/04/21	2D 3D TSV
US10738026	17	11	HGNC:10597	Isoquinoline derivatives and use thereof	Purdue Pharma L.P.	04/04/21	2D 3D TSV
US10736890	75	37	HGNC:8156	Methods for treating depressive symptoms	ALKERMES PHARMA IRELAND LIMITED	04/04/21	2D 3D TSV
US10738056	517	508		Pyrazolopyrimidinone compounds and uses thereof	Aduro BioTech Inc.	04/04/21	2D 3D TSV
US10738009	160	158	HGNC:10582	Pyridone amides as modulators of sodium channels	VERTEX PHARMACEUTICALS INCORPORATED	04/04/21	2D 3D TSV
US10736974	64	35	HGNC:3788	Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy	THE JOHNS HOPKINS UNIVERSITY	04/04/21	2D 3D TSV
US10738057	246	118	HGNC:8978 HGNC:8977	Tertiary alcohols as PI3K-γ inhibitors	Incyte Corporation	04/04/21	2D 3D TSV
US10736883	326	315	HGNC:339	Triazole furan compounds as agonists of the APJ receptor	AMGEN INC.	04/04/21	2D 3D TSV
US10723742	270	242	HGNC:29079	Biphenyl compound or salt thereof	Taiho Pharmaceutical Co., Ltd.	03/30/21	2D 3D TSV
US10730902	10	5	HGNC:6561 HGNC:6563	1,1 ′-sulfanediyl-di-beta-D-galactopyranosides as inhibitors of galectins	GALECTO BIOTECH AB	03/28/21	2D 3D TSV
US10730889	403	380	HGNC:30092	Amido spirocyclic amide and sulfonamide derivatives	FORMA TM, LLC; Genentech, Inc.	03/28/21	2D 3D TSV
US10723734	237	230	HGNC:19679	Biaryl kinase inhibitors	Bristol-Myers Squibb Company	03/28/21	2D 3D TSV
US10722495	51	51	HGNC:6863	Cyanoindazole compounds and uses thereof	Incyte Corporation	03/28/21	2D 3D TSV
US10722597	33	4	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:19086 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:4854 HGNC:4853 HGNC:18128	Cyclodextrin-panobinostat adduct	MIDATECH LTD.	03/28/21	2D 3D TSV
US10722489	10	10	HGNC:8923	D-3-phosphoglycerate dehydrogenase allosteric inhibitor and use thereof	Peking University	03/28/21	2D 3D TSV
US10723705	206	204	HGNC:13315	Heterocyclic compounds and uses thereof	Incyte Corporation	03/28/21	2D 3D TSV
US10723709	26	6	HGNC:2536 HGNC:2537 HGNC:2545	Protease inhibitors	MEDIVIR AB	03/28/21	2D 3D TSV
US10723723	220	173	HGNC:6255	Substituted bicycle heterocyclic derivatives useful as ROMK channel inhibitors	Bristol-Myers Squibb Company	03/28/21	2D 3D TSV
US10730882	34	34	HGNC:10436	2-aminoquinazoline derivatives as P70S6 kinase inhibitors	SENTINEL ONCOLOGY LIMITED	03/27/21	2D 3D TSV
US10730880	867	199	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	4,6-substituted-pyrazolo[1,5-a]pyrazines as Janus kinase inhibitors	Array BioPharma Inc.; Celgene Corporation	03/27/21	2D 3D TSV
US10730877	3210	841	HGNC:15633 HGNC:15631 HGNC:15632	4-Azaindole compounds	Bristol-Myers Squibb Company	03/27/21	2D 3D TSV
US10730868	104	95	HGNC:3540	Bicyclic heteroaryl substituted compounds	Bristol-Myers Squibb Company	03/27/21	2D 3D TSV
US10730870	267	140	HGNC:12687	Compounds and methods for the enhanced degradation of targeted proteins	ARVINAS OPERATIONS, INC.; YALE UNIVERSITY	03/27/21	2D 3D TSV
US10730865	49	49		Compounds for modulating aquaporins	APOGLYX AB	03/27/21	2D 3D TSV
US10730860	3	2	HGNC:13575	Diaminopyrimidine benzenesulfone derivatives and uses thereof	Dana-Farber Cancer Institute, Inc.	03/27/21	2D 3D TSV
US10730881	28	28	HGNC:620	Fused pyrimidine derivatives	HOFFMANN-LA ROCHE, INC.	03/27/21	2D 3D TSV
US10730866	84	72	HGNC:10597	Indole derivatives and use thereof	Purdue Pharma L.P.	03/27/21	2D 3D TSV
US10730874	328	296	HGNC:6371	Inhibitors of plasma kallikrein and uses thereof	Shire Human Genetic Therapies, Inc.	03/27/21	2D 3D TSV
US10730875	135	31	HGNC:6190 HGNC:6192 HGNC:12440	Substituted imidazo[1,2-A]pyridin-2-ylamine compounds, and pharmaceutical compositions and methods of use thereof	JN Therapeutics	03/27/21	2D 3D TSV
US10729680	63	63		5-substituted 2-(morpholin-4-yl)-1,7-naphthyridines	BAYER PHARMA AKTIENGESELLSCHAFT	03/21/21	2D 3D TSV
US10730832	130	130		Aliphatic prolinamide derivatives	ORION OPHTHALMOLOGY LLC	03/21/21	2D 3D TSV
US10729684	24	12	HGNC:10597	Alkynyl dihydroquinoline sulfonamide compounds	AMGEN INC.	03/21/21	2D 3D TSV
US10729695	29	29	HGNC:320	Amino, amido and heterocyclic compounds as modulators of RAGE activity and uses thereof	The Research Foundation for the State University of New York; New York University	03/21/21	2D 3D TSV
US10730856	12	12	HGNC:9596	Benzimidazole derivatives as EP4 ligands	BAYER PHARMA AKTIENGESELLSCHAFT	03/21/21	2D 3D TSV
US10730849	95	51		Benzo[b]thiophene compounds as STING agonists	Merck Sharp & Dohme Corp.	03/21/21	2D 3D TSV
US10730863	435	427	HGNC:7967	Bridged bicyclic compounds as farnesoid X receptor modulators	Bristol-Myers Squibb Company	03/21/21	2D 3D TSV
US10729710	17	6	HGNC:3023 HGNC:3020	Catecholamine prodrugs for use in the treatment of Parkinson's disease	H. Lundbeck A/S	03/21/21	2D 3D TSV
US10717746	178	86	HGNC:1780	Chemical compounds	ASTRAZENECA AB	03/21/21	2D 3D TSV
US10730853	36	17	HGNC:5184	Compounds as neuronal histamine receptor-3 antagonists and uses thereof	XW LABORATORIES INC.	03/21/21	2D 3D TSV
US10717737	116	115	HGNC:29079	Cyclopropylamines as LSD1 inhibitors	Incyte Corporation	03/21/21	2D 3D TSV
US10717733	462	116	HGNC:6834 HGNC:550 HGNC:6666	Haloallylamine indole and azaindole derivative inhibitors of lysyl oxidases and uses thereof	Pharmaxis Ltd.	03/21/21	2D 3D TSV
US10717734	176	44	HGNC:6834 HGNC:550 HGNC:6666	Indole and azaindole haloallylamine derivative inhibitors of lysyl oxidases and uses thereof	Pharmaxis Ltd.	03/21/21	2D 3D TSV
US10716791	42	17	HGNC:18367 HGNC:18368	Inhibitors of peptidyl arginine deiminase (PAD) enzymes and uses thereof	University Health Network	03/21/21	2D 3D TSV
US10730826	181	68	HGNC:2531 HGNC:2538 HGNC:2527 HGNC:2536 HGNC:2547 HGNC:2537 HGNC:2545 HGNC:2535	Ketone inhibitors of lysine gingipain	CORTEXYME, INC.	03/21/21	2D 3D TSV
US10717708	62	31	HGNC:3827 HGNC:3826	Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists	Bristol-Myers Squibb Company	03/21/21	2D 3D TSV
US10730850	106	106	HGNC:550	Pyridinylmethyl carbamimidoylcarbamate derivatives and their use as AOC3 inhibitors	Boehringer Ingelheim International GmbH	03/21/21	2D 3D TSV
US10717738	29	29	HGNC:3529	Pyrimidinone and its derivatives inhibiting factor XIa	ONO PHARMACEUTICAL CO., LTD.	03/21/21	2D 3D TSV
US10717742	148	137		Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors	Boehringer Ingelheim International GmbH	03/21/21	2D 3D TSV
US10730833	9	9	HGNC:348	Synthesis of diindolylmethanes and indolo[3,2-b]carbazoles, compounds formed thereby, and pharmaceutical compositions containing them	Wisconsin Alumni Research Foundation	03/21/21	2D 3D TSV
US10730830	51	25	HGNC:3165 HGNC:14299	Tetrahydronaphthalene derivative	ONO PHARMACEUTICAL CO., LTD.	03/21/21	2D 3D TSV
US10717764	402	207		Therapeutically active compounds and their methods of use	Agios Pharmaceuticals, Inc.	03/21/21	2D 3D TSV
US10729691	118	59	HGNC:11005	Treatment of infectious diseases with glucose uptake inhibitors	KADMON CORPORATION, LLC	03/21/21	2D 3D TSV
US10711036	87	87	HGNC:6819	MALT1 inhibitors and uses thereof	Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation	03/15/21	2D 3D TSV
US10711006	65	28	HGNC:4840 HGNC:3697 HGNC:1057 HGNC:1133 HGNC:6193 HGNC:6171 HGNC:2444 HGNC:3765	Selective Bruton's tyrosine kinase inhibitor and use thereof	HANGZHOU HERTZ PHARMACEUTICAL CO., LTD.	03/15/21	2D 3D TSV
US10711007	49	49	HGNC:10894	Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)	Prelude Therapeutics Incorporated	03/15/21	2D 3D TSV
US10711020	881	783		Tricyclic sulfones as RORγ modulators	Bristol-Myers Squibb Company	03/15/21	2D 3D TSV
US10709688	40	16	HGNC:3559 HGNC:3557	Agent for treating synucleinopathy	Tohoku University; National University Corporation Okayama University	03/14/21	2D 3D TSV
US10710980	616	88		Aminopyridine derivatives and their use as selective ALK-2 inhibitors	Novartis AG	03/14/21	2D 3D TSV
US10709712	2614	1072	HGNC:9829	Biaryl amide compounds as kinase inhibitors	NOVARTIS AG	03/14/21	2D 3D TSV
US10709695	2	2		Compounds as rearranged during transfection (RET) inhibitors	GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED	03/14/21	2D 3D TSV
US10709718	28	28	HGNC:2843	Inhibitors of diacylglycerol O-acyltransferase 1 (DGAT-1) and uses thereof	Metabasis Therapeutics, Inc.	03/14/21	2D 3D TSV
US10710994	297	150	HGNC:497	Oxadiazole transient receptor potential channel inhibitors	Genentech, Inc.	03/14/21	2D 3D TSV
US10711004	455	275	HGNC:497	Oxadiazole transient receptor potential channel inhibitors	Genentech, Inc.	03/14/21	2D 3D TSV
US10710986	657	656		PD-1/PD-L1 inhibitors	Gilead Sciences, Inc.	03/14/21	2D 3D TSV
US10710967	299	294	HGNC:9599	Pyrimidine derivative	ASKA PHARMACEUTICAL CO., LTD.	03/14/21	2D 3D TSV
US10710978	234	59	HGNC:11403 HGNC:11408 HGNC:18174 HGNC:11406	STK4 inhibitors for treatment of hematologic malignancies	DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE	03/14/21	2D 3D TSV
US10709719	42	10	HGNC:3167 HGNC:3165	Substituted bicyclic compounds	Bristol-Myers Squibb Company	03/14/21	2D 3D TSV
US10709709	212	203	HGNC:10894	Substituted carbonucleoside derivatives useful as anticancer agents	Pfizer Inc.	03/14/21	2D 3D TSV
US10676499	33	17	HGNC:3287	3′ end caps, 5′ end caps and combinations thereof for therapeutic RNA	NOVARTIS AG	03/11/21	2D 3D TSV
US10676464	43	43		5-hydroxytryptamine receptor 7 activity modulators and their method of use	Temple University Of The Commonwealth System of Higher Education	03/11/21	2D 3D TSV
US10676458	17	11	HGNC:4498	Antidiabetic bicyclic compounds	Merch Sharp & Dohne Corp. Rahway	03/11/21	2D 3D TSV
US10676467	113	58	HGNC:3169 HGNC:3167 HGNC:3165 HGNC:14299 HGNC:3170	Compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof	Washington University	03/11/21	2D 3D TSV
US10676457	130	129	HGNC:29079	Cyclopropylamines as LSD1 inhibitors	Incyte Corporation	03/11/21	2D 3D TSV
US10676465	188	94	HGNC:4324	GLP-1 receptor agonists and uses thereof	Pfizer Inc.	03/11/21	2D 3D TSV
US10676479	360	118	HGNC:17101	Imidazolepyridine compounds and uses thereof	Novartis AG	03/11/21	2D 3D TSV
US10676470	36	34		Inhibitors of lysine gingipain	CORTEXYME, INC.	03/11/21	2D 3D TSV
US10676469	383	182	HGNC:8154 HGNC:8156	Kappa opioid receptor antagonists and products and methods related thereto	BLACKTHORN THERAPEUTICS, INC.; THE SCRIPPS RESEARCH INSTITUTE	03/11/21	2D 3D TSV
US10676485	106	53	HGNC:6943	Macrocyclic MCL-1 inhibitors and methods of use	AbbVie Inc.	03/11/21	2D 3D TSV
US10676460	56	3	HGNC:9077 HGNC:11283 HGNC:11584 HGNC:14552 HGNC:17967 HGNC:12434 HGNC:11724 HGNC:6735 HGNC:2451 HGNC:5465 HGNC:4617 HGNC:2459 HGNC:6112 HGNC:2457 HGNC:3767 HGNC:6190 HGNC:6192 HGNC:6193 HGNC:6171 HGNC:11390 HGNC:12440 HGNC:1079 HGNC:1771 HGNC:1133 HGNC:6860 HGNC:7972 HGNC:6524 HGNC:1775	Quinazolines as potassium ion channel inhibitors	Bristol-Myers Squibb Company	03/11/21	2D 3D TSV
US10676476	30	14	HGNC:3430 HGNC:5253	Small-molecule HSP90 inhibitors	Sloan-Kettering Institute for Cancer Research	03/11/21	2D 3D TSV
US10676446	190	190	HGNC:3357	Bicyclic quinazolinone derivatives	Hoffmann-La Roche Inc.	03/10/21	2D 3D TSV
US10676434	200	178	HGNC:1133	Carbazole derivatives	Bristol-Myers Squibb Company	03/10/21	2D 3D TSV
US10675286	612	109	HGNC:8978 HGNC:8975 HGNC:8977 HGNC:8976	Heterocyclic compounds and uses thereof	Infinity Pharmaceuticals, Inc.	03/10/21	2D 3D TSV
US10676433	355	196	HGNC:5992 HGNC:8537	Indole derivatives and their use in neurodegenerative diseases	Merck Patent GmbH	03/10/21	2D 3D TSV
US10676438	16	10	HGNC:6251	KCNQ2-5 channel activator	Ono Pharmaceutical Co., Ltd.	03/10/21	2D 3D TSV
US10676431	270	127	HGNC:3827 HGNC:3826	Phenylpyrrolidinone formyl peptide 2 receptor agonists	Bristol-Myers Squibb Company	03/10/21	2D 3D TSV
US10675268	284	169	HGNC:11330 HGNC:11331 HGNC:11334 HGNC:11332 HGNC:11333	Somatostatin receptor subtype 4 (SSTR4) agonists	Centrexion Therapeutics Corporation	03/10/21	2D 3D TSV
US10675284	37	37	HGNC:6190 HGNC:8977	Treatment of B-cell malignancies by a combination JAK and PI3K inhibitors	Incyte Corporation	03/10/21	2D 3D TSV
US10703751	36	7	HGNC:6192 HGNC:6193	Amino-imidazopyridine derivatives as Janus kinase inhibitors and pharmaceutical use thereof	Leo Pharma A/S	03/08/21	2D 3D TSV
US10703741	26	16	HGNC:18368	Covalent inhibitors of PAD4	Padlock Therapeutics, Inc.	03/08/21	2D 3D TSV
US10702504	21	21	HGNC:11812	Degradation of tripartite motif-containing protein 24 (TRIM24) by conjugation of TRIM24 inhibitors with E3 ligase ligand and methods of use	DANA-FARBER CANCER INSTITUTE, INC.	03/08/21	2D 3D TSV
US10703733	457	445		MCL-1 inhibitors	Gilead Sciences, Inc.	03/08/21	2D 3D TSV
US10702498	27	15	HGNC:8154 HGNC:8156	MU opioid receptor modulators	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; FRIEDRICH-ALEXANDER-UNIVERSITAT ERLANGEN-NÜRNBERG; THE BOARD OF TRUSTEES OFTHE LELAND STANFORD JUNIOR UNIVERSITY; THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL	03/08/21	2D 3D TSV
US10703749	843	289	HGNC:8537	P2X7 modulators	Janssen Pharmaceutica NV	03/08/21	2D 3D TSV
US10708263	5	1		Salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders	GALAPAGOS NV	03/08/21	2D 3D TSV
US10703740	14	14	HGNC:13575	Substituted benzimidazoles, their preparation and their use as pharmaceuticals	Neomed Institute	03/08/21	2D 3D TSV
US10703755	351	337	HGNC:15631	Substituted purine derivative	SUMITOMO DAINIPPON PHARMA CO., LTD.	03/08/21	2D 3D TSV
US10696692	374	308	HGNC:30092	Amido-benzyl sulfone and sulfoxide derivates	TBA	03/02/21	2D 3D TSV
US10696672	157	152	HGNC:6161	Amino acid compounds and methods of use	Pliant Therapeutics, Inc.	03/02/21	2D 3D TSV
US10696682	44	44	HGNC:1771	CDK inhibitors	G1 Therapeutics, Inc.	03/02/21	2D 3D TSV
US10696661	70	69	HGNC:11305	Compounds	Exonate Limited	03/02/21	2D 3D TSV
US10696638	48	43	HGNC:10251 HGNC:10252	Compounds for inhibiting AGC kinase and pharmaceutical compositions comprising the same	INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE	03/02/21	2D 3D TSV
US10695334	98	57	HGNC:6371 HGNC:11830	Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors	Boehringer Ingelheim International GmbH	03/02/21	2D 3D TSV
US10696678	154	64	HGNC:1722	Kinase inhibitor, and preparing method and pharmaceutical use thereof	GAN & LEE PHARMACEUTICALS	03/02/21	2D 3D TSV
US10696665	61	23	HGNC:5382	Mutant IDH1 inhibitors	Eli Lilly and Company	03/02/21	2D 3D TSV
US10695337	794	388		Piperidin-4-yl azetidine derivatives as JAK1 inhibitors	Incyte Holdings Corporation; Incyte Corporation	03/02/21	2D 3D TSV
US10695347	84	40	HGNC:427	Pyrimidine derivative and use thereof	HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC.	03/02/21	2D 3D TSV
US10696660	91	36	HGNC:10251 HGNC:10252	Rho kinase inhibitors	Kadmon Corporation, LLC	03/02/21	2D 3D TSV
US10696689	23	23	HGNC:11331	Somatostatin modulators and uses thereof	CRINETICS PHARMACEUTICALS, INC.	03/02/21	2D 3D TSV
US10696655	125	125	HGNC:2348	Therapeutic compounds and uses thereof	GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.	03/02/21	2D 3D TSV
US10689373	308	149	HGNC:4849 HGNC:4848	1,2-substituted cyclopentanes as orexin receptor antagonists	TAKEDA PHARMACEUTICAL COMPANY LIMITED	02/22/21	2D 3D TSV
US10689345	273	269		1-cyano-pyrrolidine compounds as USP30 inhibitors	Mission Therapeutics Limited	02/22/21	2D 3D TSV
US10689401	50	25	HGNC:934 HGNC:933	C5-C6-oxacyclic fused iminothiazine dioxide compounds bearing an ether linker as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp.	02/22/21	2D 3D TSV
US10689705	212	71	HGNC:3690 HGNC:3689 HGNC:3688	FGFR3 fusion gene and pharmaceutical drug targeting same	Chugai Seiyaku Kabushiki Kaisha	02/22/21	2D 3D TSV
US10689346	302	246	HGNC:6371	Human plasma kallikrein inhibitors	BioCryst Pharmaceuticals, Inc.	02/22/21	2D 3D TSV
US10688100	52	13	HGNC:10261	Macrocylic compounds as ROS1 kinase inhibitors	Array BioPharma Inc.	02/22/21	2D 3D TSV
US10688093	708	647	HGNC:4037	Methods, compositions, and uses of novel Fyn kinase inhibitors	TBA	02/22/21	2D 3D TSV
US10689357	43	43	HGNC:736	N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and use thereof	NORTHEASTERN UNIVERSITY	02/22/21	2D 3D TSV
US10689398	91	89	HGNC:8157	OXA-Diazaspiro compounds having activity against pain	ESTEVE PHARMACEUTICALS, S.A.	02/22/21	2D 3D TSV
USRE48059	122	64		Piperazine-substituted benzothiophenes for treatment of mental disorders	Otsuka Pharmaceutical Co., Ltd.	02/22/21	2D 3D TSV
US10689327	30	15	HGNC:4595 HGNC:4594	Prodrug amino acid derivative	TAISHO PHARMACEUTICAL CO., LTD.	02/22/21	2D 3D TSV
US10689339	69	69	HGNC:2545	Pyrrolidine derivatives	Hoffmann-La Roche Inc.	02/22/21	2D 3D TSV
US10689362	508	124	HGNC:8804 HGNC:6342 HGNC:3765	Quinoxaline compounds as type III receptor tyrosine kinase inhibitors	Development Center for Biotechnology	02/22/21	2D 3D TSV
US10689399	23	23	HGNC:9213	Substituted 3,4,5,6,8,10,14,14a-octahydro-2h-2,6-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazocines and methods for treating viral infections	Gilead Sciences, Inc.	02/22/21	2D 3D TSV
US10689369	149	127		Substituted indazole compounds as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp.	02/22/21	2D 3D TSV
US10689376	39	39	HGNC:3356	Substituted-3H-imidazo [4,5-c] pyridine and 1H-pyrrolo[2,3-c]pyridine series of novel ectonucleotide pyrophosphatase/phosphodiesterase-1 (ENPP1) and stimulator for interferon genes (STING) modulators as cancer immunotherapeutics	Stingray Therapeutics, Inc.; The University of Utah	02/22/21	2D 3D TSV
US10689414	404	206		Therapeutically active compounds and their methods of use	Agios Pharmaceuticals, Inc.	02/22/21	2D 3D TSV
US10689367	327	233	HGNC:339	Triazole pyridyl compounds as agonists of the APJ receptor	AMGEN INC.	02/22/21	2D 3D TSV
US10689390	18	18	HGNC:13575	Tricyclic fused derivatives of 1-(cyclo)alkyl pyridin-2-one useful for the treatment of cancer	JUBILANT BIOSYS LIMITED	02/22/21	2D 3D TSV
US10689395	14	14	HGNC:13575	Tricyclic fused pyridin-2-one derivatives and their use as BRD4 inhibitors	JUBILANT BIOSYS LIMITED	02/22/21	2D 3D TSV
US10669240	500	242	HGNC:3091	5-substituted indazole-3-carboxamides and preparation and use thereof	Samumed, LLC	02/21/21	2D 3D TSV
US10669246	153	115	HGNC:8803 HGNC:76 HGNC:6342	Benzothiazol compounds and methods using the same for treating neurodegenerative disorders	1ST Biotherapeutics, Inc.	02/21/21	2D 3D TSV
US10669268	343	306	HGNC:10548	Bicyclic derivatives	Hoffmann-La Roche Inc.	02/21/21	2D 3D TSV
US10669289	209	104	HGNC:9542 HGNC:9545	Boronic acid derivatives	MERCK PATENT GMBH	02/21/21	2D 3D TSV
US10669245	37	37	HGNC:2528	Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides dipeptidyl peptidase 1 inhibitors	ASTRAZENECA AB	02/21/21	2D 3D TSV
US10669285	43	43	HGNC:10548	Condensed [1,4] diazepine compounds as autotaxin (ATX) and lysophosphatidic acid (LPA) production inhibitors	Hoffmann-La Roche Inc.	02/21/21	2D 3D TSV
US10669276	48	48		Fused pyrimidine derivatives	HOFFMANN-LA ROCHE INC.	02/21/21	2D 3D TSV
US10669271	94	30	HGNC:7794 HGNC:9644	Heterocyclic compounds as immunomodulators	Incyte Corporation	02/21/21	2D 3D TSV
US10669279	372	104	HGNC:8780 HGNC:8781 HGNC:8783	Imidazopyridazine compounds	Pfizer Inc.	02/21/21	2D 3D TSV
US10669243	10	10		Isoxazole carboxamides as irreversible SMYD inhibitors	EPIZYME, INC.	02/21/21	2D 3D TSV
US10669296	8	4		LXR agonists and uses thereof	Rgenix, Inc.	02/21/21	2D 3D TSV
US10669265	142	72	HGNC:6307 HGNC:8804 HGNC:9437	Pyridyl benzothiophenes as kinase inhibitors	ALLERGAN, INC.	02/21/21	2D 3D TSV
US10669267	65	39	HGNC:8537	Substituted N-[2-(4-phenoxypiperidin-1-yl)-2-(1,3-thiazol-5-yl)ethyl]benzamide and N-[2-(4-benzyloxypiperidin-1-yl)-2-(1,3-thiazol-5-yl)ethyl]benzamide derivatives P2X7 receptor antagonists	Axxam S.P.A.	02/21/21	2D 3D TSV
US10669273	42	36	HGNC:6059	Use of aza-tryptanthrin derivatives as inhibitors of IDO1 and/or TDO	Peking University	02/21/21	2D 3D TSV
US10683294	67	67	HGNC:1338	5-5 fused rings as C5a inhibitors	ChemoCentryx, Inc.	02/16/21	2D 3D TSV
US10683295	59	29	HGNC:11526 HGNC:6251 HGNC:11527 HGNC:11528	Chiral N-acyl-5,6,7(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-A]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor mediated disorders and chiral synthesis thereof	Ogeda SA	02/16/21	2D 3D TSV
US10683291	3	3	HGNC:3165	Heterocyclic compounds for the treatment of disease	OPPILAN PHARMA LTD.	02/16/21	2D 3D TSV
US10683290	84	80		Tricyclic compounds as anticancer agents	Bristol-Myers Squibb Company	02/16/21	2D 3D TSV
US10683309	84	42	HGNC:12008 HGNC:20692	Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same	MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN; FORSCHUNGSVERBUND BERLIN E.V.	02/16/21	2D 3D TSV
US10668071	105	100		(Aza)pyridopyrazolopyrimidinones and indazolopyrimidinones and their use	BAYER PHARMA AKTIENGESELLSCHAFT	02/15/21	2D 3D TSV
US10667515	17	17		(S)-5-ethynyl-anabasine, derivatives thereof, and related compositions and methods of making and using	Iowa State University Research Foundation, Inc.	02/15/21	2D 3D TSV
US10683279	71	68	HGNC:6857	Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	02/15/21	2D 3D TSV
US10683289	23	23	HGNC:6857	Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	02/15/21	2D 3D TSV
US10682352	117	100	HGNC:5382	Compound having mutant IDH inhibitory activity, preparation method and use thereof	SHANGHAI HAIHE PHARMACEUTICAL CO., LTD.; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES	02/15/21	2D 3D TSV
US10669227	24	9	HGNC:7175 HGNC:7176 HGNC:7166 HGNC:7159	Curcumin analogues as zinc chelators and their uses	THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK	02/15/21	2D 3D TSV
US10669234	193	147	HGNC:12513	Cyanopyrrolidines as dub inhibitors for the treatment of cancer	MISSION THERAPEUTICS LIMITED	02/15/21	2D 3D TSV
US10668167	176	62	HGNC:7978 HGNC:644 HGNC:3467 HGNC:8910	Glucocorticoid receptor agonist and immunoconjugates thereof	AbbVie Inc.	02/15/21	2D 3D TSV
US10683287	96	45	HGNC:934 HGNC:933	Heterocyclic derivatives and their use in the treatment of neurological disorders	Novartis AG	02/15/21	2D 3D TSV
US10669235	336	55	HGNC:8803 HGNC:3763 HGNC:6307 HGNC:8804 HGNC:3690 HGNC:3688	Indole derivatives and their use as protein kinase inhibitors	RESPIVERT LIMITED	02/15/21	2D 3D TSV
US10668051	56	56	HGNC:25896	Modulators of calcium release-activated calcium channel	RHIZEN PHARMACEUTICALS SA	02/15/21	2D 3D TSV
US10668033	4	4	HGNC:9602	Modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto	ARENA PHARMACEUTICALS, INC.	02/15/21	2D 3D TSV
US10668067	135	135	HGNC:10597	Pyridine sulfonamides	AMGEN INC.	02/15/21	2D 3D TSV
US10668094	92	21		Selective inhibitors of Alpha2-containing isoforms of Na,K-ATPase and use thereof for reduction of intraocular pressure	Yeda Research and Development Co. Ltd.	02/15/21	2D 3D TSV
US10669239	74	68	HGNC:8031	Tetrahydronaphthyl urea derivative	MOCHIDA PHARMACEUTICAL CO., LTD.	02/15/21	2D 3D TSV
US10660877	2542	841	HGNC:15633 HGNC:15631 HGNC:15632	Pyridyl substituted indole compounds	Bristol-Myers Squibb Company	02/08/21	2D 3D TSV
US10662159	204	60	HGNC:3553 HGNC:17038 HGNC:21398	ABHD6 and dual ABHD6/MGL inhibitors and their uses	MAKSCIENTIFIC, LLC	02/07/21	2D 3D TSV
US10660876	90	89	HGNC:2771	Amino compounds for treatment of medical disorders	Achillion Pharmaceuticals, Inc.	02/07/21	2D 3D TSV
US10662184	150	83	HGNC:10593 HGNC:10585 HGNC:10596	Benzenesulfonamide compounds and their use as therapeutic agents	Xenon Pharmaceuticals Inc.	02/07/21	2D 3D TSV
US10660898	27	27	HGNC:8972	Benzimidazole derivatives as PI3 kinase inhibitors	GLAXOSMITHKLINE LLC	02/07/21	2D 3D TSV
US10662187	134	124	HGNC:6735 HGNC:1057 HGNC:1133 HGNC:3236 HGNC:6524	Bruton's tyrosine kinase inhibitors	Zibo Biopolar Changsheng Pharmaceutical Co. Ltd.; Shanghai Institute of Materia Medica, Chinese Academy of Sciences	02/07/21	2D 3D TSV
US10662156	94	90	HGNC:6819	Guanidine derivative and medical use thereof	Toray Industries, Inc.	02/07/21	2D 3D TSV
US10662189	84	78	HGNC:8781	PDE4 inhibitor	SHIJIAZHUANG SAGACITY NEW DRUG DEVELOPMENT CO., LTD.	02/07/21	2D 3D TSV
US10662186	650	137	HGNC:1780 HGNC:1771 HGNC:1778 HGNC:1722 HGNC:1777 HGNC:1774 HGNC:1773	Substituted pyrimidines as cyclin-dependent kinase inhibitors	SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.	02/07/21	2D 3D TSV
US10654833	96	90	HGNC:6857	ASK1 isoindolin-1-one inhibitors and methods of use thereof	Hepatikos Therapeutics, LLC	02/01/21	2D 3D TSV
US10654857	68	7	HGNC:10555	Bicyclic compounds as autotaxin (ATX) and lysophosphatidic acid (LPA) production inhibitors	Hoffman-La Roche Inc.	02/01/21	2D 3D TSV
US10654835	207	69		Compounds and methods for inhibiting JAK	Dizal (Jiangsu) Pharmaceutical Co., Ltd.	02/01/21	2D 3D TSV
US10654856	20	17	HGNC:15631 HGNC:15632	Method for preparing pyrrolo[3,2-D]pyrimidine compound, and intermediates thereof	CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.	02/01/21	2D 3D TSV
US10654855	73	73	HGNC:391	Protein kinase B inhibitors	AstraZeneca AB	02/01/21	2D 3D TSV
US10654836	40	10	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Pyrimidine derivative, method for preparing same and use thereof in medicine	Zhejiang Hisun Pharmaceutical Co., Ltd.	02/01/21	2D 3D TSV
US10654866	44	21	HGNC:3467	Selective estrogen receptor degraders	Eli Lilly and Company	02/01/21	2D 3D TSV
US10654853	147	145		Spiro-condensed pyrrolidine derivatives as deubiquitylating enzymes (DUB) inhibitors	MISSION THERAPEUTICS LIMITED	02/01/21	2D 3D TSV
US10654860	35	31	HGNC:10252	Tricyclic rho kinase inhibitors	Bristol-Myers Squibb Company	02/01/21	2D 3D TSV
US10653688	302	143	HGNC:4617 HGNC:3091	6-(6-membered heteroaryl and aryl)isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	01/31/21	2D 3D TSV
US10654831	85	14	HGNC:1780 HGNC:1771 HGNC:1774 HGNC:1773 HGNC:1775	Antiproliferative pyrimidine-based compounds	G1 Therapeutics, Inc.	01/31/21	2D 3D TSV
US10654814	240	127	HGNC:4852 HGNC:14064 HGNC:13315 HGNC:4854 HGNC:4853	Bicyclic hydroxamic acids useful as inhibitors of mammalian histone deacetylase activity	KANCERA AB	01/31/21	2D 3D TSV
US10653701	103	52	HGNC:6307 HGNC:1133 HGNC:6193 HGNC:3689 HGNC:3236 HGNC:3688	Substituted quinazolines for inhibiting kinase activity	NEUPHARMA, INC.	01/31/21	2D 3D TSV
US10647665	39	33		Biaryl urea derivative or salt thereof and preparation process and use for the same	Fudan University	01/25/21	2D 3D TSV
US10647719	107	5	HGNC:10555 HGNC:1373	Bicyclic compounds as dual ATX/CA inhibitors	Hoffmann-La Roche Inc.	01/25/21	2D 3D TSV
US10647706	40	14	HGNC:6026 HGNC:6027	Chemokine CXCR1 and CXCR2 receptor antagonist compounds, and use thereof in the treatment of chemokine-mediated pathologies	GALDERMA RESEARCH & DEVELOPMENT	01/25/21	2D 3D TSV
US10647694	45	40	HGNC:427	Diphenylaminopyrimidine and triazine compound, and pharmaceutical composition and use thereof	ARROMAX PHARMATECH CO., LTD.	01/25/21	2D 3D TSV
US10647700	14	14		EZH2 inhibitor and use thereof	TARAPEUTICS SCIENCE INC.	01/25/21	2D 3D TSV
US10646575	3	3	HGNC:2717	Heterocyclic degronimers for target protein degradation	C4 Therapeutics, Inc.	01/25/21	2D 3D TSV
US10646492	366	342	HGNC:8977	Heterocyclylamines as PI3K inhibitors	Incyte Corporation; Incyte Holdings Corporation	01/25/21	2D 3D TSV
US10647720	614	333	HGNC:6192 HGNC:11491	Pyrimido-pyridazinone compounds and methods of use thereof	Asan BioSciences, LLC	01/25/21	2D 3D TSV
US10647727	66	47		Substituted pyrazolo/imidazolo bicyclic compounds as PDE2 inhibitors	Merck Sharp & Dohme Corp.	01/25/21	2D 3D TSV
US10647686	82	50	HGNC:11396 HGNC:11395	Substituted pyrimidines for preventing or treating cancer and inflammatory diseases	KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY	01/25/21	2D 3D TSV
US10647713	620	601		TYK2 inhibitors and uses thereof	Nimbus Lakshmi, Inc.	01/25/21	2D 3D TSV
US10647708	46	46	HGNC:10894	Tetrahydroisoquinoline derived PRMT5-inhibitors	CTXT PTY. LTD	01/25/21	2D 3D TSV
US10639286	194	172		Alkoxy compounds for disease treatment	ACUCELA INC.	01/18/21	2D 3D TSV
US10640498	69	68		Compounds	MISSION THERAPEUTICS LIMITED	01/18/21	2D 3D TSV
US10640533	114	19	HGNC:2524 HGNC:24059 HGNC:9537	Epoxyketone compounds for enzyme inhibition	CENTRAX INTERNATIONAL, INC.	01/18/21	2D 3D TSV
US10640486	86	85	HGNC:1133	Heteroarylcarboxamide derivatives as plasma kallikrein inhibitors	Boehringer Ingelheim International GmbH	01/18/21	2D 3D TSV
US10640495	646	615	HGNC:8031	Heterocycle derivatives having TrkA inhibitory activity	Shionogi & Co., Ltd.	01/18/21	2D 3D TSV
US10640503	158	158	HGNC:29079	Imidazopyridines and imidazopyrazines as LSD1 inhibitors	Incyte Corporation	01/18/21	2D 3D TSV
US10639284	329	312	HGNC:17635	Immunomodulator compounds	ChemoCentryx, Inc.	01/18/21	2D 3D TSV
US10640491	20	20	HGNC:1133	Inhibitors of bruton's tyrosine kinase	HOFFMANN-LA ROCHE INC.	01/18/21	2D 3D TSV
US10640534	402	205		Therapeutically active compositions and their methods of use	Agios Pharmaceuticals, Inc.	01/18/21	2D 3D TSV
US10633384	113	113	HGNC:10555	Diazaspirocycloalkane and azaspirocycloalkane	Hoffmann-La Roche Inc.	01/12/21	2D 3D TSV
US10632126	676	168	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR4 inhibitors	Incyte Corporation	01/10/21	2D 3D TSV
US10633379	264	130		Bromodomain inhibitors	AbbVie Inc.	01/10/21	2D 3D TSV
US10633389	1029	1023	HGNC:23393	CARM1 inhibitors and uses thereof	Epizyme, Inc.	01/10/21	2D 3D TSV
US10632122	116	115		Compositions and methods for treating toxoplasmosis, cryptosporidiosis and other apicomplexan protozoan related diseases	University of Washington	01/10/21	2D 3D TSV
US10633345	302	248	HGNC:6371	Human plasma kallikrein inhibitors	BioCryst Pharmaceuticals, Inc.	01/10/21	2D 3D TSV
US10632171	152	130	HGNC:6932 HGNC:4479	Melanocortin receptor-specific peptides	Palatin Technologies, Inc.	01/10/21	2D 3D TSV
US10633348	39	16	HGNC:4840 HGNC:1133 HGNC:4195 HGNC:7972	Methods to treat lymphoplasmacytic lymphoma	Dana-Farber Cancer Institute, Inc.	01/10/21	2D 3D TSV
US10633375	111	107	HGNC:3529	Oxopicolinamide derivative, preparation method therefor and pharmaceutical use thereof	Jinagsu Hengrui Medicine Co., Ltd; Shanghai Hengrui Pharmaceutical Co., Ltd.	01/10/21	2D 3D TSV
US10633388	19	14	HGNC:4421	Pyrazolopyrimidone derivatives and methods of use thereof	Shanghai Hengrui Pharmaceutical Co., ltd.; Jiangsu Hangrui Medicine Co., Ltd.	01/10/21	2D 3D TSV
US10633373	123	72	HGNC:6307 HGNC:8804 HGNC:9437	Pyridyl benzothiophenes as kinase inhibitors	Allergan, Inc.	01/10/21	2D 3D TSV
US10604514	334	150	HGNC:4617 HGNC:3091	6-(5-membered heteroaryl)isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	12/21/20	2D 3D TSV
US10604534	38	19	HGNC:934 HGNC:933	C5-C6-oxacyclic fused iminothiadiazine dioxide compounds bearing an ether linker as BACE inhibitors, compositions, and their use	Merck Sharp & Dohme Corp.	12/21/20	2D 3D TSV
US10604535	251	240		Compounds, compositions and methods	Denali Therapeutics Inc.	12/21/20	2D 3D TSV
US10604531	11	11	HGNC:3527	Enhancer of zeste homolog 2 inhibitors	GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED	12/21/20	2D 3D TSV
US10604536	59	54	HGNC:8772	Substituted cyclopropanes as PDE-10 inhibitors	Sunovion Pharamaceuticals Inc.	12/21/20	2D 3D TSV
US10604508	11	11	HGNC:1133	2,3-dihydro-isoindole-1-one derivative as BTK kinase suppressant, and pharmaceutical composition including same	CrystalGenomics, Inc.	12/20/20	2D 3D TSV
US10603310	14	12	HGNC:933	2-amino-6-(difluoromethyl)-5,5-difluoro-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors	H. Lundbeck A/S	12/20/20	2D 3D TSV
US10618929	21	20	HGNC:15631	3-substituted 5-amino-6H-thiazolo[4,5-D]pyrimidine-2, 7-dione compounds for the treatment and prophylaxis of virus infection	Hoffmann-La Roche Inc.	12/20/20	2D 3D TSV
US10618900	52	27	HGNC:4597 HGNC:4593	5-aromatic alkynyl substituted benzamide compound and preparation method, pharmaceutical composition, and use thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	12/20/20	2D 3D TSV
US10618914	79	43	HGNC:11364 HGNC:11362	6-aryl-7-substituted-3-(1H-pyrazol-5-yl)-7H-[1,2,4]triazolo[3,4-B][1,3,4]thiadiazines as inhibitors of the STAT3 pathway with anti-proliferative activity	University of Pittsburgh—Of the Commonwealth System of Higher Education	12/20/20	2D 3D TSV
US10603330	131	65	HGNC:663 HGNC:664	Arginase inhibitors as therapeutics	Mars, Incorporated	12/20/20	2D 3D TSV
US10618886	36	17	HGNC:5184	Compounds as neuronal histamine receptor-3 antagonists and uses thereof	XW LABORATORIES INC.	12/20/20	2D 3D TSV
US10604489	172	171	HGNC:8156	Compounds for the treatment of pain	Alkermes, Inc.	12/20/20	2D 3D TSV
US10603320	9	3	HGNC:10258	Compounds useful for inhibiting ROR-gamma-t	Eli Lilly and Company	12/20/20	2D 3D TSV
US10618884	16	1	HGNC:427	Deuterated diaminopyrimidine compounds and pharmaceutical compositions comprising such compounds	Suzhou Zelgen Biopharmaceuticals Co., Ltd.	12/20/20	2D 3D TSV
US10618912	55	18	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:8031 HGNC:8032 HGNC:8033 HGNC:427 HGNC:10261 HGNC:11397	Diaryl macrocycles as modulators of protein kinases	Turning Point Therapeutics, Inc.	12/20/20	2D 3D TSV
US10618903	287	262	HGNC:17967	Heteroaryl substituted aminopyridine compounds	Bristol-Myers Squibb Company	12/20/20	2D 3D TSV
US10618916	68	68		Heterocyclic compounds as immunomodulators	Incyte Corporation	12/20/20	2D 3D TSV
US10604504	262	222	HGNC:1133	Indole carboxamide compounds	Bristol-Myers Squibb Company	12/20/20	2D 3D TSV
US10618913	114	37	HGNC:8775 HGNC:8774 HGNC:8776	Macrocycles as PDE1 inhibitors	H. Lundbeck A/S	12/20/20	2D 3D TSV
US10618897	168	161	HGNC:2730	Spiroindolinones as DDR1 inhibitors	Hoffmann-La Roche Inc.	12/20/20	2D 3D TSV
US10604502	112	111	HGNC:29079	Substituted 5-cyanoindole compounds and uses thereof	Novartis AG	12/20/20	2D 3D TSV
US10618902	256	249	HGNC:3691	Substituted pyrido[2,3-d]pyrimidines as inhibitors of protein kinases	Celgene CAR LLC; Sanofi	12/20/20	2D 3D TSV
US10618910	58	29		Tricyclic heterocycles as BET protein inhibitors	Incyte Corporation	12/20/20	2D 3D TSV
US10597383	35	35		Bicyclic proline compounds	Genentech, Inc.	12/14/20	2D 3D TSV
US10597387	19	8	HGNC:4840 HGNC:1133 HGNC:7972	Methods to treat lymphoplasmacytic lymphoma	Dana-Farber Cancer Institute, Inc.	12/14/20	2D 3D TSV
US10597399	40	39	HGNC:270	Substituted triazolopiperazine PARP inhibitor, preparation method therefor and use thereof	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	12/14/20	2D 3D TSV
US10597382	16	15	HGNC:6857	Tetrazole containing apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof	Enanta Pharmaceuticals, Inc.	12/14/20	2D 3D TSV
US10596172	747	259	HGNC:1079 HGNC:1133 HGNC:6193 HGNC:6171 HGNC:3236	2,4-disubstituted pyrimidines useful as kinase inhibitors	Celgene CAR LLC	12/13/20	2D 3D TSV
US10597366	413	325	HGNC:12680 HGNC:3374	Aryl ethers and uses thereof	Peloton Therapeutics, Inc.	12/13/20	2D 3D TSV
US10596184	158	76	HGNC:8978 HGNC:8977	Aza-heteroaryl compounds as PI3K-gamma inhibitors	Incyte Corporation	12/13/20	2D 3D TSV
US10617673	8	8		Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes	Jenrin Discovery, LLC	12/13/20	2D 3D TSV
US10617706	43	42	HGNC:17768	Compounds for cancer chemotherapeutic sensitization	REGENTS OF THE UNIVERSITY OF MINNESOTA; THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES	12/13/20	2D 3D TSV
US10597367	724	191		Metabotropic glutamate receptor negative allosteric modulators (NAMs) and uses thereof	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	12/13/20	2D 3D TSV
US10610125	24	5	HGNC:5382 HGNC:6541 HGNC:6535	Methods and compositions for cell-proliferation-related disorders	Agios Pharmaceuticals, Inc.	12/13/20	2D 3D TSV
US10617692	4	4	HGNC:6192	Pyrrolopyrimidine comprising cyclopentyl substituent	CENTAURUS BIOPHARMA CO.; CHIA TAI TIANQING PHARMACEUTICAL GROUP CO.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.	12/13/20	2D 3D TSV
US10597377	268	258	HGNC:11331	Somatostatin modulators and uses thereof	CRINETICS PHARMACEUTICALS, INC.	12/13/20	2D 3D TSV
US10617676	596	594	HGNC:4586	Substituted 1H-imidazo[4,5-b]pyridin-2(3H)-ones and their use as GluN2B receptor modulators	JANSSEN PHARMACEUTICA NV	12/13/20	2D 3D TSV
US10617680	423	397	HGNC:2348	Therapeutic compounds	CELGENE QUANTICEL RESEARCH, INC.	12/13/20	2D 3D TSV
US10617654	78	26	HGNC:286	Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas	The USA, as represented by the Secretary, Department of Health and Human Services; SRI International	12/13/20	2D 3D TSV
US10590106	12	6	HGNC:6307	Certain chemical entities, compositions, and methods	NeuPharma, Inc.	12/08/20	2D 3D TSV
US10590105	56	56		1,3-dihydroxy-phenyl derivatives useful as immunomodulators	Bristol-Meyers Squibb Company	12/07/20	2D 3D TSV
US10611727	18	18		1-[1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives	UNIVERSITAT DE BARCELONA; FUNACIÓ INSTITUT DE RECERCA BIOMÉDICA; IPROTEOS S.L.	12/07/20	2D 3D TSV
US10611730	212	212	HGNC:13628	Benzimidazolone and benzothiazolone compounds and their use as AMPA receptor modulators	Janssen Pharmaceutica NV	12/07/20	2D 3D TSV
US10610539	14	14		Cardiac glycoside analogs and their use in methods for inhibition of viral infection	The John Hopkins University	12/07/20	2D 3D TSV
US10590130	121	63	HGNC:6251	Chemical compounds	AstraZeneca AB	12/07/20	2D 3D TSV
US10590114	215	161	HGNC:18618	Compounds, compositions, and methods	Denali Therapautics Inc.	12/07/20	2D 3D TSV
US10611770	26	26	HGNC:427	Condensed-ring pyrimidylamino derivative, preparation method therefor, and intermediate, pharmaceutical composition and applications thereof	GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD.	12/07/20	2D 3D TSV
US10590075	29	29		Cyanopyrrolidine derivatives as inhibitors for DUBs	MISSION THERAPEUTICS LIMITED	12/07/20	2D 3D TSV
US10611751	15	15	HGNC:3020	Dopamine D1 receptor positive allosteric modulators	Eli Lilly and Company	12/07/20	2D 3D TSV
US10590109	85	24		Heterocyclic compounds used as FGFR inhibitors	Nanjing InnoCare Pharma Tech Co., Ltd.	12/07/20	2D 3D TSV
US10611763	116	114	HGNC:17071	Histone demethylase inhibitors	Celgene Quanticel Research, Inc.	12/07/20	2D 3D TSV
US10611777	156	69	HGNC:8979 HGNC:8978 HGNC:8980 HGNC:8977	Imidazopyridazine compounds and their use	HUTCHISON MEDIPHARMA LIMITED	12/07/20	2D 3D TSV
US10611728	246	97	HGNC:6251 HGNC:8157	Isoindoline compositions and methods for treating neurodegenerative disease	COGNITION THERAPEUTICS, INC.	12/07/20	2D 3D TSV
US10590139	60	60	HGNC:8031	Method of treatment using substituted imidazo[1,2b]pyridazine compounds	Array BioPharma Inc.	12/07/20	2D 3D TSV
US10611766	279	95	HGNC:1133 HGNC:3236	Pyrazolopyrimidine derivatives as BTK inhibitors for the treatment of cancer	Loxo Oncology Inc.	12/07/20	2D 3D TSV
US10590132	289	159	HGNC:6251	Selective estrogen receptor down-regulators	AstraZeneca AB	12/07/20	2D 3D TSV
US10590077	7	7	HGNC:18083	TRPV4 antagonists	GlaxoSmithKline Intellectual Property Development Limited	12/07/20	2D 3D TSV
US10590140	785	438	HGNC:11048	Tetrahydropyrimidodiazepine and dihydropyridodiazepine compounds for treating pain and pain related conditions	ESTEVE PHARMACEUTICALS, S.A.	12/07/20	2D 3D TSV
US10570125	40	16	HGNC:2160 HGNC:2159	(Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles	Centrexion Therapeutics Corporation	11/30/20	2D 3D TSV
US10570116	153	53	HGNC:270 HGNC:11941 HGNC:15677	1,4-dicarbonyl-piperidyl derivatives	Merck Patent GmbH	11/30/20	2D 3D TSV
US10568884	22	22		Compounds and compositions as protein kinase inhibitors	Array BioPharma Inc.	11/30/20	2D 3D TSV
US10570167	249	149	HGNC:8021	Ectonucleotidase inhibitors and methods of use thereof	Calithera Biosciences, Inc.	11/30/20	2D 3D TSV
US10570155	21	8	HGNC:9829 HGNC:1097	Imidazooxazole derivative having antitumor effect, and pharmaceutical composition including same	KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY	11/30/20	2D 3D TSV
US10570118	43	40	HGNC:1133	Isoquinolones as BTK inhibitors	Boehringer Ingelheim International GmbH	11/30/20	2D 3D TSV
US10570123	100	51	HGNC:10251 HGNC:10252	Pharmacokinetically improved compounds	SURFACE LOGIX, LLC	11/30/20	2D 3D TSV
US10570140	42	42	HGNC:29652	Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)	Prelude Therapeutics Incorporated	11/30/20	2D 3D TSV
US10570077	7	7	HGNC:3467	Substituted (4'-hydroxyphenyl)cyclohexane compounds and uses thereof as selective agonists of the estrogen receptor beta isoform	Marquette University; Concordia University Inc.	11/30/20	2D 3D TSV
US10570121	412	114	HGNC:3527	Substituted dihydroisoquinolinone compounds	Pfizer Inc.	11/30/20	2D 3D TSV
US10570156	42	42	HGNC:8772	Substituted imidazo[1,2-a]pyridines as PDE-10 inhibitors	SUNOVION PHARMACEUTICALS INC.	11/30/20	2D 3D TSV
US10570141	14	7	HGNC:1777 HGNC:1773	Substituted pyrrolopyrimidine CDK inhibitor, pharmaceutical composition containing same and use thereof	CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; CENTAURUS BIOPHARMA CO., LTD.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.	11/30/20	2D 3D TSV
US10568876	141	138	HGNC:16940	Tetrahydroisoquinoline derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2	Merck Sharp & Dohme Corp.	11/30/20	2D 3D TSV
US10568888	26	13	HGNC:8781 HGNC:8783	Tricyclic compounds as modulators of TNF-alpha synthesis and as PDE4 inhibitors	vTv Therapeutics LLC	11/30/20	2D 3D TSV
US10584127	26	11	HGNC:4586 HGNC:6251 HGNC:2625	3,3-difluoropiperidine carbamate heterocyclic compounds as NR2B NMDA receptor antagonists	Rugen Holdings (Cayman) Limited	11/29/20	2D 3D TSV
US10584111	25	22	HGNC:4597	4-(3-cyanophenyl)-6-pyridinylpyrimidine mGlu5 modulators	Heptares Therapeutics Limited	11/29/20	2D 3D TSV
US10577368	79	61	HGNC:268 HGNC:262 HGNC:263	A3 adenosine receptor agonists	The United States of America, as represented by the Secretary, Department of Health and Human Services; Saint Louis University	11/29/20	2D 3D TSV
US10584120	58	58	HGNC:9753	Benzimidazole compounds and use thereof for treating Alzheimer's Disease or Huntington's Disease	National Health Research Institutes; Academia Sinica	11/29/20	2D 3D TSV
US10577374	360	356	HGNC:1133	Bruton's tyrosine kinase inhibitors	Sunesis Pharmaceuticals, Inc.; Biogen MA Inc.	11/29/20	2D 3D TSV
US10584104	18	18	HGNC:17989	Carboxylic acid URAT1 inhibitor containing diarylmethane structure, preparation method and use thereof	TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH CO., LTD.	11/29/20	2D 3D TSV
US10584121	10	10		Heteroaryl substituted benzoic acids as RORgammaT inhibitors and uses thereof	Merck Sharp & Dohme Corp.	11/29/20	2D 3D TSV
US10584116	51	51	HGNC:497	Heterocyclic sulfonamide derivative and medicine containing same	EA Pharma Co., Ltd.	11/29/20	2D 3D TSV
US10568874	8	8	HGNC:17635	Indane-amines as PD-L1 antagonists	ChemoCentryx, Inc.	11/29/20	2D 3D TSV
US10583140	12	12		Ingenol analogs, pharmaceutical compositions and methods of use thereof	GlaxoSmithKline Intellectual Property Development Limited	11/29/20	2D 3D TSV
US10584114	82	41	HGNC:9967	Inhibitors of RET	BLUEPRINT MEDICINES CORPORATION	11/29/20	2D 3D TSV
US10577383	78	37	HGNC:7218	Macrocyclic inhibitors of myeloperoxidase	Bristol-Myers Squibb Company	11/29/20	2D 3D TSV
US10584098	12	12		Quinolone-3-diarylethers	Oregon Health & Science University	11/29/20	2D 3D TSV
US10584132	20	12	HGNC:10852 HGNC:10850	SHMT inhibitors	The Trustees of Princeton University	11/29/20	2D 3D TSV
US10584103	224	211	HGNC:8039	Small molecule agonists of neurotensin receptor 1	SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE	11/29/20	2D 3D TSV
US10584135	348	174	HGNC:3023 HGNC:3024	Substituted 3,6-diazabicyclo[3.2.0]heptanes	INDIVIOR UK LIMITED	11/29/20	2D 3D TSV
US10577373	1366	1143		TYK2 inhibitors and uses thereof	Nimbus Lakshimi, Inc.	11/29/20	2D 3D TSV
US10583137	116	56	HGNC:1165 HGNC:28923	Triazole DAGLα inhibitors	THE SCRIPPS RESEARCH INSTITUTE; LEIDEN UNIVERSITY	11/29/20	2D 3D TSV
US10584134	79	69	HGNC:17961	Use of physiological cooling active ingredients, and agents containing such active ingredients	SYMRISE AG; BASF SE	11/29/20	2D 3D TSV
US10561662	73	73	HGNC:19995	4-oxo-3,4-dihydro-1,2,3-benzotriazine modulators of GPR139	Takeda Pharmaceutical Company Limited	11/22/20	2D 3D TSV
US10562893	49	22	HGNC:6171 HGNC:11719 HGNC:12434	Benzimidazoles derivatives as Tec kinases family inhibitors	GB005, INC.	11/22/20	2D 3D TSV
US10562890	16	15	HGNC:10471	Cancer therapeutics	UNIVERSITY OF VIRGINIA PATENT FOUNDATION	11/22/20	2D 3D TSV
US10562861	41	14	HGNC:6251 HGNC:15631 HGNC:15632	Carboxylic acid compounds	Sumitomo Dainippon Pharma Co., Ltd.	11/22/20	2D 3D TSV
US10562853	189	63	HGNC:3023 HGNC:5286 HGNC:277	Compounds for treating disorders sensitive to serotoninergic regulation controlled by the 5-HT1A receptors	NEUROLIXIS; UNIVERSITE JAGELLONE	11/22/20	2D 3D TSV
US10562888	6	1	HGNC:3682 HGNC:3690 HGNC:3689 HGNC:3688	Crystalline FGFR4 inhibitor compound and uses thereof	Eisai R&D Management Co., LTD.	11/22/20	2D 3D TSV
US10562878	1149	222	HGNC:11050 HGNC:11049	Cycloalkylamines as monoamine reuptake inhibitors	SUNOVION PHARAMCEUTICALS INC.	11/22/20	2D 3D TSV
US10562844	14	14		HYPDH inhibitors and methods of use for the treatment of kidney stones	Wake Forest University Health Sciences; UAB Research Foundation	11/22/20	2D 3D TSV
US10562850	103	100	HGNC:6371	Human plasma kallikrein inhibitors	BioCryst Pharmaceuticals, Inc.	11/22/20	2D 3D TSV
US10562902	175	164	HGNC:17967	IRAK4 inhibitor and use thereof	Beijing Hanmi Pharmaceutical Co., Ltd.	11/22/20	2D 3D TSV
US10562900	131	57	HGNC:6307 HGNC:3690 HGNC:3689 HGNC:3688	Indazole compounds as FGFR kinase inhibitor, preparation and use thereof	Shanghai Haihe Pharmaceutical Co., Ltd.; Shanghai Institute of Materia Medica, Chinese Academy of Sciences	11/22/20	2D 3D TSV
US10562910	9	9	HGNC:7967	Nitrogen-containing tricyclic compounds and uses thereof in medicine	NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED	11/22/20	2D 3D TSV
US10561656	9	5	HGNC:8775 HGNC:8774	Organic compounds	INTRA-CELLULAR THERAPIES, INC.	11/22/20	2D 3D TSV
US10562882	43	41		Piperidine derivatives for use in the treatment or prevention of psychiatric and neurological conditions	Takeda Pharmaceutical Company Limited	11/22/20	2D 3D TSV
US10562854	32	16	HGNC:1232 HGNC:12680	Prolyl hydroxylase inhibitors	AERPIO THERAPEUTICS, INC.	11/22/20	2D 3D TSV
US10561657	26	23	HGNC:6192	Pyrrolopyrimidine compound	Centaurus Biophrama Co., Ltd.; Chia Tai Tianqing Pharmaceutical Group Co., Ltd.; Lianyungang Runzhong Pharmaceutical Co., Ltd.	11/22/20	2D 3D TSV
US10562891	435	427		Quinazolinones as PARP14 inhibitors	Ribon Therapeutics Inc.	11/22/20	2D 3D TSV
US10561655	27	27	HGNC:9644	SHP2 inhibitors and uses thereof	SYNBLia Therapeutics, Inc.	11/22/20	2D 3D TSV
US10562916	209	206	HGNC:8772	Substituted quinoxalines as PDE-10 inhibitors	Sunovion Pharmaceuticals, Inc.	11/22/20	2D 3D TSV
US10562887	182	177	HGNC:10252	Triazolones and tetrazolones as inhibitors of ROCK	Bristol-Myers Squibb Company	11/22/20	2D 3D TSV
US10577367	528	508	HGNC:17967	IRAK4 inhibiting agents	BIOGEN MA INC.	11/21/20	2D 3D TSV
US10550117	11	11	HGNC:6853	2-azabicyclo[3.1.0]hexan-3-one derivatives and methods of use	Genentech, Inc.	11/20/20	2D 3D TSV
US10577353	28	27		5-(n-[6,5]-fused bicyclic aryl tetrahydroisoquinolin-6-yl) pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication	ViiV HEALTHCARE UK (NO.5) LIMITED	11/20/20	2D 3D TSV
US10577360	308	153	HGNC:8156 HGNC:1399	Arylamide derivatives having multimodal activity against pain	ESTEVE PHARMACEUTICALS, S.A.	11/20/20	2D 3D TSV
US10577354	6	6		Bis-pyridazine compounds and their use in treating cancer	Cancer Research Technology Limited	11/20/20	2D 3D TSV
US10577352	67	37	HGNC:3236	Cot modulators and methods of use thereof	Gilead Sciences, Inc.	11/20/20	2D 3D TSV
US10577361	69	33	HGNC:3023 HGNC:3024	Dopamine D3 receptor antagonists having a morpholine moiety	INDIVIOR UK LIMITED	11/20/20	2D 3D TSV
US10550140	43	43	HGNC:2771	Ether compounds for treatment of complement mediated disorders	Achillion Pharmaceuticals, Inc.	11/20/20	2D 3D TSV
US10576087	116	58		Fused tricyclic compounds as Raf kinase inhibitors	BEIGENE, LTD.	11/20/20	2D 3D TSV
US10550102	161	159		Indane and indoline derivatives and the use thereof as soluble guanylate cyclase activators	NOVARTIS AG	11/20/20	2D 3D TSV
US10550127	20	20	HGNC:4498	Indanylaminoazadihydrobenzofuranylacetic acids, pharmaceutical compositions for the treatment of diabetes	Boehringer Ingelheim International GmbH	11/20/20	2D 3D TSV
US10550118	56	24	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	JAK inhibitors containing a 4-membered heterocyclic amide	Theravance Biopharma R&D IP, LLC	11/20/20	2D 3D TSV
US10550114	65	21	HGNC:391	Kinase inhibitors and their use in cancer therapy	TECHNISCHE UNIVERSITÄT DORTMUND	11/20/20	2D 3D TSV
US10577330	196	28	HGNC:6160 HGNC:6161 HGNC:6163 HGNC:6141 HGNC:6156	Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists	Saint Louis University	11/20/20	2D 3D TSV
US10577336	169	87	HGNC:11330 HGNC:11331 HGNC:11334 HGNC:11332 HGNC:11333	Morpholine and 1,4-oxazepane amides as somatostatin receptor subtype 4 (SSTR4) agonists	Boehringer Ingelheim International GmbH	11/20/20	2D 3D TSV
US10544150	223	221	HGNC:11528	NK-3 receptor selective antagonist compounds, pharmaceutical composition and methods for use in NK-3 receptors mediated disorders	Ogeda SA	11/20/20	2D 3D TSV
US10550125	10	5	HGNC:2459 HGNC:2457	Prodrugs of imidazotriazine compounds as CK2 inhibitors	Bristol-Myers Squibb Company	11/20/20	2D 3D TSV
US10550105	855	803		Pyridazinones as PARP7 inhibitors	Ribon Therapeutics Inc.	11/20/20	2D 3D TSV
US10577308	216	36	HGNC:10588 HGNC:10596	Sodium channel modulators	The Florey Institute; The University of Melbourne	11/20/20	2D 3D TSV
US10576064	115	107		Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors	Boehringer Ingelheim International GmbH	11/20/20	2D 3D TSV
US10577363	985	980		Substituted piperidine compounds	EPIZYME, INC.	11/20/20	2D 3D TSV
US10550096	5	3	HGNC:10894	Tetrahydroisoquinolines as PRMT5 inhibitors	CTXT PTY LTD	11/20/20	2D 3D TSV
US10556883	18	9	HGNC:195 HGNC:7155	Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine and cosmetics	GALDERMA RESEARCH & DEVELOPMENT	11/13/20	2D 3D TSV
US10556902	124	122	HGNC:7056	Glycosidase inhibitors	Asceneuron SA	11/13/20	2D 3D TSV
US10556885	634	302	HGNC:4617 HGNC:3091	Isoquinolin-3-YL carboxamides and preparation and use thereof	Samumed, LLC	11/13/20	2D 3D TSV
US10556892	65	37	HGNC:736	Piperazinyl methanone NAAA inhibitors	The Regents of the University of California; Fondazione Istituto Italiano di Technologia	11/13/20	2D 3D TSV
US10556908	120	119	HGNC:29079	Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors	Incyte Corporation	11/13/20	2D 3D TSV
US10556914	100	100	HGNC:4507	Substituted isoxazolopyridazinones and isothiazolopyridazinones and methods of use	ABBVIE INC.; ABBVIE DEUTSCHLAND GMBH & CO. KG	11/13/20	2D 3D TSV
US10555944	1229	556		Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors	Eli Lilly and Company	11/13/20	2D 3D TSV
US10556900	75	71	HGNC:8031	TrkA kinase inhibitors, compositions and methods thereof	Merck Sharp & Dohme Corp.	11/13/20	2D 3D TSV
US10538491	153	153		4,5-substituted picolinamide and picolinonitrile metabotropic glutamate receptor 2 negative allosteric modulators	Vanderbilt University	11/09/20	2D 3D TSV
US10538523	3	3	HGNC:4076	4-(biphen-3-yl)-1H-pyrazolo[3,4-c]pyridazine derivatives of formula (I) as GABA receptor modulators for use in the treatment of epilepsy and pain	PFIZER LIMITED	11/09/20	2D 3D TSV
US10538528	107	46	HGNC:391 HGNC:10430	5H-pyrrolo[2,3-D]pyrimidin-6(7H)-one derivative	Taiho Pahrmaceutical Co., Ltd.	11/09/20	2D 3D TSV
US10538497	213	208	HGNC:6059	Compounds as indoleamine 2,3-dioxygenase inhibitors	Merck Sharp & Dohme Corp.	11/09/20	2D 3D TSV
US10538496	192	188	HGNC:19086	Methods using HDAC11 inhibitors	FORMA Therapeutics, Inc.; H. Lee Moffitt Cancer Center and Research Institute, Inc.	11/09/20	2D 3D TSV
US10537571	140	66	HGNC:3690 HGNC:3691 HGNC:3689 HGNC:3688	Pyrimidine FGFR4 inhibitors	EISAI R&D MANAGEMENT CO., LTD.	11/09/20	2D 3D TSV
US10538517	40	39	HGNC:3688	Quinolone derivatives as FGFR inhibitors	Principia Biopharma, Inc.	11/09/20	2D 3D TSV
US10538508	126	61	HGNC:17432 HGNC:1936	Substituted amino triazoles useful as human chitinase inhibitors	OncoArendi Therapeutics S.A.	11/09/20	2D 3D TSV
US10550091	176	87	HGNC:7968	1,4,5-substituted 1,2,3-triazole analogues as antagonists of the pregnane X receptor	St. Jude Children''s Research Hospital	11/07/20	2D 3D TSV
US10550100	455	114	HGNC:7160 HGNC:195 HGNC:7159 HGNC:221	5-[3-[piperzin-1-yl]-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS 4 and 5 inhibitors for treating E.G. osteoarthritis	GALAPAGOS NV	11/07/20	2D 3D TSV
US10548313	35	34		Acetyl-CoA carboxylase modulators	Monsanto Technology LLC	11/07/20	2D 3D TSV
US10550080	137	49	HGNC:10593 HGNC:10597	Acyl sulfonamide NaV1.7 inhibitors	Bristol-Myers Squibb Company	11/07/20	2D 3D TSV
US10550073	35	25	HGNC:2623 HGNC:6876	Benzamide derivative	CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd.	11/07/20	2D 3D TSV
US10550089	124	62	HGNC:3538	Inhibitors of protease-activated receptor-2	Heptares Therapeutics Limited	11/07/20	2D 3D TSV
US10544132	133	130	HGNC:6973	Isoindolinone inhibitors of the MDM2-p53 interaction having anticancer activity	ASTEX THERAPEUTICS LIMITED; CANCER RESEARCH TECHNOLOGY LIMITED	11/07/20	2D 3D TSV
US10548897	8	8		KSR antagonists	Icahn School of Medicine at Mount Sinai	11/07/20	2D 3D TSV
US10544136	207	163	HGNC:3167 HGNC:3165	Modulators of sphingosine phosphate receptors	The Scripps Research Institute	11/07/20	2D 3D TSV
US10550099	297	182		Quinolinone pyrimidines compositions as mutant-isocitrate dehydrogenase inhibitors	Forma Therapeutics, Inc.	11/07/20	2D 3D TSV
US10548896	122	119	HGNC:29079	Treatment of relapsed and/or refractory solid tumors and non-Hodgkin's lymphomas	Celgene Quanticel Research, Inc.	11/07/20	2D 3D TSV
US10544143	3210	878	HGNC:15633 HGNC:15631 HGNC:15632	4-azaindole compounds	Bristol-Myers Squibb Company	11/02/20	2D 3D TSV
US10544152	10	9	HGNC:5295	5-HT2CR agonist analogs	The Board of Regents of The University of Texas System; University of Houston System	11/02/20	2D 3D TSV
US10544146	4	1		Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors	FEDORA PHARMACEUTICALS INC.	11/02/20	2D 3D TSV
US10544151	11	11	HGNC:6307	Compounds and uses thereof	Kala Pharmaceuticals, Inc.	11/02/20	2D 3D TSV
US10544141	90	76		Derivatives and methods of treating hepatitis B infections	NOVIRA THERAPEUTICS, INC.	11/02/20	2D 3D TSV
US10544133	168	150	HGNC:17967	Heteroaryl substituted pyridyl compounds useful as kinase modulators	Bristol-Myers Squibb Company	11/02/20	2D 3D TSV
US10533001	238	213	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:11491	Inhibitors of protein kinases	PORTOLA PHARMACEUTICALS, INC.	11/02/20	2D 3D TSV
US10544128	732	235	HGNC:4617 HGNC:3091	Isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	11/02/20	2D 3D TSV
US10544130	1497	489		Metallo-beta-lactamase inhibitors	Merck Sharp & Dohme Corp.	11/02/20	2D 3D TSV
US10544147	185	117	HGNC:8977	Purine inhibitors of human phosphatidylinositol 3-kinase delta	Merck Sharp & Dohme Corp.	11/02/20	2D 3D TSV
US10533010	416	376	HGNC:6943 HGNC:992 HGNC:990	Substituted indole Mcl-1 inhibitors	Vanderbilt University	11/02/20	2D 3D TSV
US10544126	111	107		Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases	TAKEDA PHARMACEUTICAL COMPANY LIMITED	11/02/20	2D 3D TSV
US10532048	12	12	HGNC:1113	Tetrahydroisoquinolin-1-one derivative or salt thereof	Seldar Pharma Inc.	11/02/20	2D 3D TSV
US10544095	38	38	HGNC:11708	3-indol substituted derivatives, pharmaceutical compositions and methods for use	Pfizer Inc.; iTeos Therapeutics	11/01/20	2D 3D TSV
US10544117	30	30	HGNC:5302	5-hydroxytryptamine receptor 7 activity modulators and their method of use	Temple University—Of The Commonwealth System of Higher Education	11/01/20	2D 3D TSV
US10543221	20	13		Beta-lactamase inhibitors, formulations, and uses thereof	University of South Florida; The Regents of the University of California	11/01/20	2D 3D TSV
US10544120	343	331	HGNC:19679	Biaryl kinase inhibitors	Bristol-Myers Squibb Company	11/01/20	2D 3D TSV
US10544106	98	96	HGNC:1133	Certain chemical entities, compositions, and methods	NEUPHARMA, INC.	11/01/20	2D 3D TSV
US10544104	437	141	HGNC:4840 HGNC:11283 HGNC:76	Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases	UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR CO	11/01/20	2D 3D TSV
US10543207	74	73		Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders	ARDELYX, INC.	11/01/20	2D 3D TSV
US10544075	8	4	HGNC:11799 HGNC:11796	Derivatives of sobetirome	OREGON HEALTH & SCIENCE UNIVERSITY	11/01/20	2D 3D TSV
US10543198	75	75	HGNC:29079	Inhibitor of lysine specific demethylase-1	Celgene Quanticel Research, Inc.	11/01/20	2D 3D TSV
US10543199	18	5	HGNC:427	Macrocycle and composition comprising thereof	Shenzhen TargetRx, Inc.	11/01/20	2D 3D TSV
US10543194	6	6		Organic compounds	INTRA-CELLULAR THERAPIES, INC.	11/01/20	2D 3D TSV
US10544110	36	35	HGNC:644	Small molecule inhibitors of the nuclear translocation of androgen receptor for the treatment of castration-resistant prostate cancer	University of Pittsburgh—Of the Commonwealth System of Higher Education	11/01/20	2D 3D TSV
US10544113	206	201	HGNC:5302	Thiazolidinone compounds and use thereof	National Health Research Institute; Regents of the University of Minnesota	11/01/20	2D 3D TSV
US10543183	12	6	HGNC:7966 HGNC:7965	Treatment and diagnosis of melanoma	The Rockefeller University	11/01/20	2D 3D TSV
US10543213	122	118	HGNC:29079	Treatment of relapsed and/or refractory solid tumors and non-hodgkin's lymphomas	Celgene Quanticel Research, Inc.	11/01/20	2D 3D TSV
US10526325	98	57	HGNC:8810	Bicyclic heterocyclic derivatives	Merck Patent GmbH	10/25/20	2D 3D TSV
US10526329	367	214	HGNC:3357	Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders	GALAPAGOS NV	10/25/20	2D 3D TSV
US10526336	212	98	HGNC:4849 HGNC:4848	Fused heteroaryl derivatives as orexin receptor antagonists	Merck, Sharp & Dohme Corp.	10/25/20	2D 3D TSV
US10526330	112	16	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	JAK kinase inhibitor compounds for treatment of respiratory disease	Theravance Biopharma R&D IP, LLC	10/25/20	2D 3D TSV
US10525036	90	58	HGNC:6877 HGNC:6871	Spirocyclic compounds	Recurium IP Holdings, LLC	10/25/20	2D 3D TSV
US10513534	17	11		2′-chloro nucleoside analogs for HCV infection	IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER	10/24/20	2D 3D TSV
US10513522	84	41	HGNC:6190 HGNC:6192	Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as JAK inhibitors	Incyte Corporation; Incyte Holdings Corporation	10/24/20	2D 3D TSV
US10512634	132	40	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:19086 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:4854 HGNC:4853 HGNC:18128	Benzimidazole derivates useful as inhibitors of mammalian histone deacetylase activity	KANCERA AB	10/24/20	2D 3D TSV
US10513493	31	31	HGNC:29079	Cyclopropylamines as LSD1 inhibitors	Incyte Corporation	10/24/20	2D 3D TSV
US10513512	7	7	HGNC:3023	Flavanone derivatives, and preparation method and use thereof	Xuanwu Hospital of Capital Medical University	10/24/20	2D 3D TSV
US10513523	249	246	HGNC:4571	Imidazopyrazines and pyrazolopyrimidines and their use as AMPA receptor modulators	Janssen Pharmaceutica NV	10/24/20	2D 3D TSV
US10513499	22	22	HGNC:19288	Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase	TES Pharma S.r.l.	10/24/20	2D 3D TSV
US10513518	46	38	HGNC:6255	Inhibitors of the renal outer medullary potassium channel	Merck Sharp & Dohme Corp.	10/24/20	2D 3D TSV
US10512644	125	47	HGNC:8153 HGNC:8154 HGNC:8156	Oligomer-opioid agonist conjugates	Inheris Pharmaceuticals, Inc.	10/24/20	2D 3D TSV
US10513524	10	5	HGNC:8795 HGNC:8775	PDE9 inhibitors with imidazo triazinone backbone and imidazo pyrazinone backbone for treatment of peripheral diseases	H. LUNDBECK A/S	10/24/20	2D 3D TSV
US10513514	34	32	HGNC:20001	Piperidine compounds as PCSK9 inhibitors	SHENZHEN SALUBRIS PHARM CO LTD.	10/24/20	2D 3D TSV
US10513507	13	11	HGNC:12630	Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors	FORMA Therapeutics, Inc.	10/24/20	2D 3D TSV
US10513520	6	6	HGNC:4912	Sulfamide and sulfamate inhibitors of hHint1	Regents of the University of Minnesota	10/24/20	2D 3D TSV
US10519167	3	3	HGNC:10894	3-oxa-8-azabicyclo[3.2.1]octane derivatives and their use in the treatment of cancer and hemoglobinopathies	CTXT PTY LTD	10/19/20	2D 3D TSV
US10519153	34	11	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Fused imidazo-piperidine JAK inhibitors	Theravance Biopharma R&D IP, LLC	10/19/20	2D 3D TSV
US10519177	802	696		Heterocyclic compounds and uses thereof	Plexxikon Inc.	10/19/20	2D 3D TSV
US10519118	167	165	HGNC:29079	KDM1A inhibitors for the treatment of disease	Imago Biosciences, Inc.	10/19/20	2D 3D TSV
US10517849	9	9	HGNC:29079	LSD1 inhibitors and medical uses thereof	Constellation Pharmaceuticals, Inc.	10/19/20	2D 3D TSV
US10517872	30	15	HGNC:17967	Pyridazinone macrocycles as IRAK inhibitors and uses thereof	Merck Patent GmbH	10/19/20	2D 3D TSV
US10519163	252	89	HGNC:7027 HGNC:12446	Pyrrolopyrimidine derivatives as TAM inhibitors	Incyte Corporation	10/19/20	2D 3D TSV
US10517878	110	106	HGNC:6871	Serine/threonine kinase inhibitors	GENENTECH, INC.	10/19/20	2D 3D TSV
US10517858	327	107	HGNC:19310 HGNC:8987	Thiazolecarboxamides and pyridinecarboxamide compounds useful as PIM kinase inhibitors	Incyte Holdings Corporation; Incyte Corporation	10/19/20	2D 3D TSV
US10512632	603	190	HGNC:8775 HGNC:8774 HGNC:8776	1 H-pyrazolo[4,3-B]pyridines as PDE1 inhibitors	H. Lundbeck A/S	10/18/20	2D 3D TSV
US10508119	51	49	HGNC:436	Pyrazole derivatives useful as 5-lipdxygenase activating protein (FLAP) inhibitors	ASTRAZENECA AB	10/18/20	2D 3D TSV
US10508120	1366	1156		TYK2 inhibitors and uses thereof	Nimbus Lakshimi, Inc.	10/18/20	2D 3D TSV
US10508115	134	73	HGNC:15631 HGNC:6018	Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor	Bristol-Myers Squibb Company	10/18/20	2D 3D TSV
US10508104	531	514	HGNC:339	6-hydroxy-5-(phenyl/heteroarylsulfonyl)pyrimidin-4(1H)-one as APJ agonists	Bristol-Myers Squibb Company	10/12/20	2D 3D TSV
US10501438	16	16	HGNC:13575	Aryl-substituted dihydroquinolinones, their preparation and their use as pharmaceuticals	Neomed Institute	10/12/20	2D 3D TSV
US10508103	138	51	HGNC:11892	Benzimidazole-linked indole compound acting as novel divalent IAP antagonist	MEDSHINE DISCOVERY INC.	10/12/20	2D 3D TSV
US10508109	306	303	HGNC:17287	Bicyclic compound and use thereof for inhibiting SUV39H2	ONCOTHERAPY SCIENCE, INC.	10/12/20	2D 3D TSV
US10501436	207	36	HGNC:171 HGNC:1076 HGNC:172 HGNC:175	Compounds and methods of use	Medivation Technologies LLC	10/12/20	2D 3D TSV
US10500194	30	30		Covalent small molecule DCN1 inhibitors and therapeutic methods using the same	THE REGENTS OF THE UNIVERSITY OF MICHIGAN	10/12/20	2D 3D TSV
US10501473	12	12		Fused heterocyclic ring compounds and method of treating retinal disease using same	THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC)	10/12/20	2D 3D TSV
US10501467	122	66	HGNC:270 HGNC:272 HGNC:15677 HGNC:273	Fused tetra or penta-cyclic dihydrodiazepinocarbazolones as PARP inhibitors	BEIGENE, LTD.	10/12/20	2D 3D TSV
US10501440	42	26	HGNC:6371	Heteroarylcarboxamide derivatives as plasma kallikrein inhibitors	Boehringer Ingelheim International GmbH	10/12/20	2D 3D TSV
US10508105	148	117	HGNC:4596	Indazole compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction	Vanderbilt University	10/12/20	2D 3D TSV
US10508102	28	13	HGNC:11892	Inhibitors of cellular necrosis and related methods	President and Fellows of Harvard College; Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences	10/12/20	2D 3D TSV
US10508099	951	303	HGNC:4617 HGNC:3091	Isoquinolin-3-yl carboxamides and preparation and use thereof	Samumed, LLC	10/12/20	2D 3D TSV
US10501452	149	37	HGNC:3023	Lactam compound derivative and application thereof	NHWA PHARMA. CORPORATION	10/12/20	2D 3D TSV
US10508107	58	20	HGNC:6251 HGNC:17734 HGNC:11049	Morpholine derivative	Hoffmann-La Roche Inc.	10/12/20	2D 3D TSV
US10501451	28	15		Selective NR2B antagonists	Bristol-Myers Squibb Company	10/12/20	2D 3D TSV
US10501411	555	283		Substituted benzamides	Hoffmann-La Roche Inc.	10/12/20	2D 3D TSV
US10501458	72	37	HGNC:11708 HGNC:6059	Substituted bicyclic fused ring compounds as indoleamine-2,3-dioxygenase inhibitors	Iomet Pharma Ltd.; Merck Sharp & Dohme Corp.	10/12/20	2D 3D TSV
US10501449	69	68	HGNC:6255	Substituted nitrogen containing compounds	Bristol-Myers Squibb Company	10/12/20	2D 3D TSV
US10501435	18	5	HGNC:4177	Substituted quinazoline compounds and uses thereof for modulating glucocerebrosidase activity	Northwestern University	10/12/20	2D 3D TSV
US10508108	131	121		Tricyclic compounds as inhibitors of mutant IDH enzymes	Merck Sharp & Dohme Corp.	10/12/20	2D 3D TSV
US10501466	33	33	HGNC:12757	WDR5 inhibitors and modulators	Vanderbilt University	10/12/20	2D 3D TSV
US10507215	42	14	HGNC:6833 HGNC:6834 HGNC:404	Compounds for the treatment of addiction	Amygdala Neurosciences, Inc.	10/02/20	2D 3D TSV
US10508088	214	193	HGNC:4852 HGNC:14065 HGNC:14064 HGNC:19086 HGNC:14063 HGNC:14068 HGNC:14067 HGNC:13315 HGNC:4854 HGNC:4853 HGNC:18128	Methods using HDAC11 inhibitors	FORMA Therapeutics, Inc.	10/02/20	2D 3D TSV
US10494380	32	31	HGNC:2623	Nitrogen-containing tricyclic derivatives having HIV replication inhibitory activity	Shionogi & Co., Ltd.	10/02/20	2D 3D TSV
US10508086	253	218	HGNC:8605 HGNC:270	PARG inhibitory compounds	Cancer Research Technology Limited	10/02/20	2D 3D TSV
US10507209	33	11	HGNC:3432 HGNC:3430 HGNC:3236	Quinazoline derivatives substituted by aniline, preparation method and use thereof	XUANZHU PHARMA CO, LTD.	10/02/20	2D 3D TSV
US10508098	13	13	HGNC:12630	Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors	FORMA Therapeutics, Inc.	10/02/20	2D 3D TSV
US10493060	92	59	HGNC:6877 HGNC:6871	Spirocyclic compounds	Recurium IP Holdings, LLC	10/02/20	2D 3D TSV
US10508083	266	256	HGNC:4849	Substituted piperidine compound and use thereof	Takeda Pharmaceutical Company Limited	10/02/20	2D 3D TSV
US10494376	120	118	HGNC:10894	Tetrahydroisoquinoline derived PRMT5-inhibitors	CTXT PTY. LTD.	10/02/20	2D 3D TSV
US10479795	816	404	HGNC:8978 HGNC:8977	Substituted imidazo[2,1-f][1,2,4]triazines, substituted imidazo[1,2-a]pyridines and substituted imidazo[1,2-b]pyridazines as PI3K-gamma inhibitors	Incyte Corporation	09/26/20	2D 3D TSV
US10479803	38	29	HGNC:6190 HGNC:8977	Bicyclic heteroarylaminoalkyl phenyl derivatives as PI3K inhibitors	Incyte Corporation	09/25/20	2D 3D TSV
US9975885	182	31		Broad-spectrum non-covalent coronavirus protease inhibitors	PURDUE RESEARCH FOUNDATION	09/25/20	2D 3D TSV
US10479788	156	155	HGNC:12401	Compounds that inhibit MPS1 kinase	Cancer Research Technology Limited	09/25/20	2D 3D TSV
US10479794	202	66	HGNC:8772	Cyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxyamide	Boehringer Ingelheim International GmbH	09/25/20	2D 3D TSV
US10478426	8	7		Enhancer of Zeste Homolog 2 inhibitors	GLAXOSMITHKLINE LLC	09/25/20	2D 3D TSV
US10479798	32	32	HGNC:3009	Six-membered ring benzo derivatives as DPP-4 inhibitor and use thereof	EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES	09/25/20	2D 3D TSV
US10479784	603	576	HGNC:882	Substituted pyrazin-2-amines as inhibitors of ATR kinase	VERTEX PHARMACEUTICALS INCORPORATED	09/25/20	2D 3D TSV
US10478424	2922	955	HGNC:15633 HGNC:15631 HGNC:15632	[1,2,4]triazolo[1,5-a]pyridinyl substituted indole compounds	Bristol-Myers Squibb Company	09/24/20	2D 3D TSV
USRE47740	6	6	HGNC:6027	Aminopyridinecarboxamides as CXCR2 modulators	Syntrix Biosystems Inc.	09/20/20	2D 3D TSV
US10487111	12	12	HGNC:10906	IBAT inhibitors for the treatment of liver diseases	Albireo AB	09/20/20	2D 3D TSV
US10487086	77	77	HGNC:3529	Macrocycles as factor XIa inhibitors	Bristol-Myers Squibb Company	09/20/20	2D 3D TSV
US10485800	204	202	HGNC:6850	Mixed lineage kinase inhibitors for HIV/AIDS therapies	The University of Rochester; Board of Regents of the University of Nebraska	09/20/20	2D 3D TSV
US10487087	38	25	HGNC:4324	Positive allosteric modulators of the GLP-1 receptor	Vanderbilt University	09/20/20	2D 3D TSV
US10487092	126	124		Pyrazolopyridinamines as MKNK1 and MKNK2 inhibitors	BAYER PHARMA AKTIENGESELLSCHAFT	09/20/20	2D 3D TSV
US10485803	106	42	HGNC:6190 HGNC:6192 HGNC:6193 HGNC:12440	Pyrimidine compounds as JAK kinase inhibitors	THERAVANCE BIOPHARMA R&D IP, LLC	09/20/20	2D 3D TSV
US10487083	60	15		Small molecule inhibitors of the JAK family of kinases	Janssen Pharmaceutica NV	09/20/20	2D 3D TSV
US10478423	74	37	HGNC:6342 HGNC:3765	Substituted indazole derivatives active as kinase inhibitiors	NERVIANO MEDICAL SCIENCES S.R.L.	09/20/20	2D 3D TSV
US10487084	22	13	HGNC:15631 HGNC:6018	Toll-like receptor 7 (TLR7) agonists having a heterobiaryl moiety, conjugates thereof, and methods and uses therefor	Bristol-Myers Squibb Company	09/20/20	2D 3D TSV
US10472354	838	389	HGNC:8534	1,3-thiazol-2-yl substituted benzamides	Bayer Aktiengesellschaft	09/14/20	2D 3D TSV
US10472358	196	86		1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins	Incyte Corporation	09/14/20	2D 3D TSV
US10472324	9	9		2-cyano-3-cyclopropyl-3-hydroxy-N-aryl-thioacrylamide derivatives	ALGIAX PHARMACEUTICALS GMBH	09/14/20	2D 3D TSV
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US10472344	12	7	HGNC:3529 HGNC:6357	Factor XIa inhibitors	Merck Sharp & Dohme Corp.	09/14/20	2D 3D TSV
US10472367	5	5	HGNC:7029	Imidazo[1,2-B][1,2,4]triazines as c-Met inhibitors	INCYTE INCORPORATION; INCYTE HOLDINGS CORPORATION	09/14/20	2D 3D TSV
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US10464927	98	49	HGNC:1777 HGNC:1773	2,4-disubstituted pyrimidines as CDK inhibitors	Shanghai Xunhe Pharmaceutical Technology Co. Ltd.	09/08/20	2D 3D TSV
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US10464907	29	29		Compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof, and medical use thereof	INDUSTRY ACADEMIC COOPERATION FOUNDATION KEIMYUNG UNIVERSITY	09/08/20	2D 3D TSV
US10464902	10	10	HGNC:6307	Multi-tyrosine kinase inhibitors derivatives and methods of use	Ontogenesis, LLC	09/08/20	2D 3D TSV
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US10450313	162	54	HGNC:3690 HGNC:3689 HGNC:3688	Bicyclic heterocycles as FGFR inhibitors	Incyte Holdings Corporation	08/31/20	2D 3D TSV
US10450298	7	6	HGNC:3357	PET Imaging agents	Novartis AG	08/31/20	2D 3D TSV
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US10450296	510	168	HGNC:19310 HGNC:8987	Heterocyclic compounds useful as Pim kinase inhibitors	Incyte Corporation	08/30/20	2D 3D TSV
US10457672	128	128	HGNC:15983	γ-diketones as Wnt/β-catenin signaling pathway activators	Samumed, LLC	08/24/20	2D 3D TSV
US10323028	67	55		1,3,4-thiadiazole compounds and their use in treating cancer	AstraZeneca AB	08/24/20	2D 3D TSV
US10442759	21	21		1-sulfonamido-4-aryloxy compounds, and preparation method and medicinal application thereof	CHINA PHARMACEUTICAL UNIVERSITY	08/24/20	2D 3D TSV
US10457647	40	40	HGNC:1133	Amino pyrimidine derivatives	Novartis AG	08/24/20	2D 3D TSV
US10323037	118	118	HGNC:1133	Aminopyridazinone compounds as protein kinase inhibitors	JIANGSU HENGRUI MEDICINE CO., LTD.	08/24/20	2D 3D TSV
US10435408	19	19	HGNC:5302	Azepine derivatives as 5-HT7 receptor modulators	Korea Institute of Science and Technology	08/24/20	2D 3D TSV
US10377755	15	15	HGNC:990	BCL-2 inhibitors	Newave Pharmaceutical Inc.	08/24/20	2D 3D TSV
US10442772	248	182		Benzimidazol-2-amines as mIDH1 inhibitors	BAYER PHARMA AKTIENGESELLSCHAFT	08/24/20	2D 3D TSV
US10457669	927	912	HGNC:6871	Benzolactam compounds as protein kinase inhibitors	OTSUKA PHARMACEUTICAL CO., LTD.	08/24/20	2D 3D TSV
US10307425	116	115		Compositions and methods for treating toxoplasmosis, cryptosporidiosis and other apicomplexan protozoan related diseases	University of Washington	08/24/20	2D 3D TSV
US10376513	368	348	HGNC:8977	Heterocyclylamines as PI3K inhibitors	Incyte Holdings Corporation	08/24/20	2D 3D TSV
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US10457677	471	137	HGNC:8979 HGNC:8978 HGNC:795 HGNC:3942	Imidazolonylquinolines and the use thereof as ATM kinase inhibitors	Merck Patent GmbH	08/24/20	2D 3D TSV
US10323013	21	21	HGNC:3449	Inhibitors of the IRE-1/XBP-1 pathway and methods of using thereof	H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.	08/24/20	2D 3D TSV
US10441590	9	2	HGNC:5302 HGNC:5301 HGNC:3023 HGNC:5286 HGNC:5294	Methods for treating pulmonary hypertension	Reviva Pharmaceuticals, Inc.	08/24/20	2D 3D TSV
US10399948	138	60		Negative allosteric modulators of metabotropic glutamate receptor 3	Vanderbilt University	08/24/20	2D 3D TSV
US10456385	31	31	HGNC:1960	Pharmaceutical composition comprising pyridone derivatives	SK BIOPHARMACEUTICALS CO., LTD.	08/24/20	2D 3D TSV
US10399980	544	539	HGNC:12607	Purinones as ubiquitin-specific protease 1 inhibitors	FORMA Therapeutics, Inc.	08/24/20	2D 3D TSV
US10442808	127	124		Pyrazolo pyrimidine derivatives and their use as MALT1 inhbitors	Novartis AG	08/24/20	2D 3D TSV
US10329300	80	80	HGNC:3430	Pyrazolo[3,4-d]pyrimidine compound or salt thereof	TAIHO PHARMACEUTICAL CO., LTD.	08/24/20	2D 3D TSV
US10442810	438	145	HGNC:7027 HGNC:12446	Pyrrolotriazine compounds as TAM inhibitors	Incyte Corporation	08/24/20	2D 3D TSV
US10301261