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Patent: (prefix with "US" like US6078908)
PatentDataPatent TitleOrganizationDepositionDownloads
US9751886 33 4-amino-6-phenyl-6,7-dihydro[1,2,3]triazolo[1,5-A]pyrazine derivatives as inhibitors of beta-secretase (BACE) Janssen Pharmaceutica NV 07/11/192D 3D TSV
US9751873 161 Aryl sultam derivatives as RORc modulators Genentech, Inc. 07/11/192D 3D TSV
US9751885 801 Cyclopropanamine compound and use thereof Takeda Pharmaceutical Company Limited 07/11/192D 3D TSV
US9751856 6 Ethynyl derivatives HOFFMANN-LA ROCHE INC. 07/11/192D 3D TSV
US9751854 484 Heteroaryls and uses thereof Millennium Pharmaceuticals, Inc. 07/11/192D 3D TSV
US9751888 236 Heterocyclic compounds and uses thereof Infinity Pharmaceuticals, Inc. 07/11/192D 3D TSV
US9751881 118 Inhibitors of the renal outer medullary potassium channel Merck Sharp & Dohme Corp. 07/11/192D 3D TSV
US9751837 187 Kinase inhibitors RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED 07/11/192D 3D TSV
US9750744 68 Macrocyclic compounds as Trk kinase inhibitors Array BioPharma, Inc. 07/11/192D 3D TSV
US9750748 14 Pyridazinones as DAAO enzyme inhibitors Takeda Pharmaceutical Company Limited 07/11/192D 3D TSV
US9751832 42 Selective histone deactylase 6 inhibitors H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois 07/11/192D 3D TSV
US9751843 148 Substituted uracils and use thereof Bayer Pharma Aktiengesellschaft 07/11/192D 3D TSV
US9751850 11 TRPA1 antagonists ABBVIE INC. 07/11/192D 3D TSV
US9744173 132 2-amino 6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl-1,3-thiazol-4-yl amides Pfizer Inc. 07/05/192D 3D TSV
US9745284 120 2-pyridyloxy-4-ether orexin receptor antagonists Merck Sharp & Dohme Corp. 07/05/192D 3D TSV
US9745265 128 4-heteroaryl substituted benzoic acid compounds as RORgammaT inhibitors and uses thereof Merck Sharp & Dohme Corp. 07/05/192D 3D TSV
US9745289 262 Aldosterone synthase inhibitors Boehringer Ingelheim International GmbH 07/05/192D 3D TSV
US9745304 64 Amidoimidazopyridazines as MKNK-1 kinase inhibitors BAYER PHARMA AKTIENGESELLSCHAFT 07/05/192D 3D TSV
US9744252 20 Compounds for binding to the platelet specific glycoprotein IIb/IIIa and their use for imaging of thrombi PIRAMAL IMAGING SA 07/05/192D 3D TSV
US9745307 46 Compounds that are ERK inhibitors Merck Sharp & Dohme Corp. 07/05/192D 3D TSV
US9745328 898 Flap modulators Janssen Pharmaceutica NV 07/05/192D 3D TSV
US9745321 142 Fused pyrimidine compound, intermediate, preparation method therefor, and composition and application thereof SHANGHAI YINGLI PHARMACEUTICAL CO., LTD 07/05/192D 3D TSV
US9745317 28 Heterocyclic compounds and their use as dopamine D1 ligands Pfizer Inc. 07/05/192D 3D TSV
US9745310 199 Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same SK BIOPHARMACEUTICALS CO., LTD. 07/05/192D 3D TSV
US9745324 83 Iminothiadiazepane dioxide compounds as BACE inhibitors, compositions, and their use Merck Sharp & Dohme Corp. 07/05/192D 3D TSV
US9745282 100 Indoline compounds as aldosterone synthase inhibitors Merck Sharp & Dohme Corp; ElexoPharm GmbH 07/05/192D 3D TSV
US9744148 96 Kallikrein 7 inhibitors SIXERA Pharma AB 07/05/192D 3D TSV
US9745291 277 PRMT5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof Epizyme, Inc. 07/05/192D 3D TSV
US9744172 287 Pyrazolopyrimidine compounds for the treatment of cancer The University of North Carolina at Chapel Hill 07/05/192D 3D TSV
US9745287 36 Pyrimidines and use thereof Purdue Pharma L.P. 07/05/192D 3D TSV
US9745311 266 Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors Incyte Corporation; Incyte Holdings Corporation 07/05/192D 3D TSV
US9745283 328 Uracil derivatives as AXL and c-MET kinase inhibitors IGNYTA, INC. 07/05/192D 3D TSV
US9738626 7 Antagonists of prostaglandin EP3 receptor Pfizer Inc. 07/01/192D 3D TSV
US9737516 44 Bicyclic heterocycles as bet protein inhibitors Incyte Corporation 07/01/192D 3D TSV
US9738641 20 Bicyclic inhibitors Kalvista Pharmaceuticals Limited 07/01/192D 3D TSV
US9737544 120 Compounds ASTEX THERAPEUTICS LIMITED 07/01/192D 3D TSV
US9738658 36 Compounds as diacylglycerol acyltransferase inhibitors GlaxoSmithKline LLC 07/01/192D 3D TSV
US9738637 297 Histone demethylase inhibitors Celgene Quantical Research, Inc. 07/01/192D 3D TSV
US9738630 17 Inhibitors of lysine methyl transferase Bristol-Myers Squibb Company 07/01/192D 3D TSV
US9737522 17 NMDA receptor modulators and uses related thereto Emory University 07/01/192D 3D TSV
US9738632 20 Phenyl and benzodioxinyl substituted indazoles derivatives AstraZeneca AB; Bayer Pharma Aktiengesellschaft 07/01/192D 3D TSV
US9738668 30 Phosphonate derivatives and methods of use thereof in the treatment of Alzheimer's disease University of Kansas 07/01/192D 3D TSV
US9737542 111 Pyrrolotriazine kinase inhibitors Bristol-Myers Squibb Company 07/01/192D 3D TSV
US9738676 7 Selected macrolides with PDE4-inhibiting activity BASILEA PHARMACEUTICA AG 07/01/192D 3D TSV
US9737525 20 Small molecule activators of NRF2 pathway The General Hospital Corporation; The Regents of the University of California 07/01/192D 3D TSV
US9738628 36 Substituted 1H-indazol-1-OL analogs as inhibitors of beta catenin/Tcf protein-protein interactions University of Utah Research Foundation 07/01/192D 3D TSV
US9738640 16 Substituted benzamide derivatives as in vitro MAO-B inhibitors “NTZ LAB” LTD. 07/01/192D 3D TSV
US9738649 771 Tetrahydro-pyrimidoazepines as modulators of TRPV1 JANSSEN PHARMACEUTICA N.V. 07/01/192D 3D TSV
US9738655 635 Tetrahydroisoquinolines containing substituted azoles as factor XIa inhibitors Bristol-Myers Squibb Company 07/01/192D 3D TSV
US9730929 33 Substituted aminoimidazopyridazines BAYER INTELLECTUAL PROPERTY GMBH 06/26/192D 3D TSV
US9732104 43 Ether compounds for treatment of complement mediated disorders Achillion Pharmaceuticals, Inc. 06/24/192D 3D TSV
US9732037 63 2-aminopyridine-based selective neuronal nitric oxide synthase inhibitors Northwestern University 06/23/192D 3D TSV
US9732060 560 Aminotriazine derivative and pharmaceutical composition comprising the same SHIONOGI & CO., LTD. 06/23/192D 3D TSV
US9732094 901 Arylquinazolines Merck Patent GmbH 06/23/192D 3D TSV
US9732075 1982 Benzimidazole-proline derivatives IDORSIA PHARMACEUTICALS LTD 06/23/192D 3D TSV
US9732088 116 C2-carbocyclic iminothiazine dioxides as BACE inhibitors, compositions, and their use Merck Sharp & Dohme Corp. 06/23/192D 3D TSV
US9732103 16 Carbamate, ester, and ketone compounds for treatment of complement mediated disorders Achillion Pharmaceuticals, Inc. 06/23/192D 3D TSV
US9732061 76 Cinnoline derivatives useful as CB-1 receptor inverse agonists Janssen Pharmaceutica NV 06/23/192D 3D TSV
US9732087 30 Diamino-pyridine, pyrimidine, and pyridazine modulators of the histamine H4 receptor JANSSEN PHARMACEUTICA N.V. 06/23/192D 3D TSV
US9732093 691 FLAP modulators JANSSEN PHARMACEUTICA NV 06/23/192D 3D TSV
US9732066 239 Heterocyclic derivative and pharmaceutical drug NIPPON SHINY AKU CO., LTD. 06/23/192D 3D TSV
US9730939 366 Heterocyclylamines as PI3K inhibitors Incyte Holdings Corporation; Incyte Corporation 06/23/192D 3D TSV
US9732063 194 Kinase inhibitors RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED 06/23/192D 3D TSV
US9732044 8 N-(pyrid-4-yl)amides and N-(pyrimidin-4-yl)amides and their pharmaceutical and cosmetic use GALDERMA RESEARCH & DEVELOPMENT 06/23/192D 3D TSV
US9732072 30 PRMT5 inhibitors and uses thereof Epizyme, Inc. 06/23/192D 3D TSV
US9732097 26 Process for the synthesis of a phosphoinositide 3-kinase inhibitor Incyte Corporation 06/23/192D 3D TSV
US9730940 387 Purine inhibitors of human phosphatidylinositol 3-kinase delta Merck Sharp & Dohme 06/23/192D 3D TSV
US9732085 36 Pyridinone and pyrimidinone derivatives as factor Xia ONO PHARMACEUTICAL CO., LTD. 06/23/192D 3D TSV
US9730931 144 Pyrimidine FGFR4 inhibitors EISAI R&D Management Co., Ltd. 06/23/192D 3D TSV
US9730934 33 Quinazoline derivatives substituted by aniline, preparation method and use thereof XUANZHU PHARMA CO., LTD. 06/23/192D 3D TSV
US9730937 1155 RAF kinase modulator compounds and methods of use thereof AMBIT BIOSCIENCES CORPORATION 06/23/192D 3D TSV
US9732092 23 Substituted 2,3,4,5,7,9,13,13a-octahydropyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]OXAZEPINES and methods for treating viral infections Gilead Sciences, Inc. 06/23/192D 3D TSV
US10196387 88 Carbazole compounds useful as bromodomain inhibitors Bristol-Myers Squibb Company 06/16/192D 3D TSV
US10196396 240 Compounds antagonizing A3 adenosine receptor, method for preparing them, and medical-use thereof HANDOK INC. 06/16/192D 3D TSV
US10196436 116 Inhibitors of the fibroblast growth factor receptor BLUEPRINT MEDICINES CORPORATION 06/16/192D 3D TSV
US10196393 56 JAK inhibitors containing a 4-membered heterocyclic amide THERAVANCE BIOPHARMA R&D IP, LLC 06/16/192D 3D TSV
US10196404 3 MCL-1 inhibitors and methods of use thereof AstraZeneca AB 06/16/192D 3D TSV
US10196390 466 TYK2 inhibitors and uses thereof Nimbus Lakshmi, Inc. 06/16/192D 3D TSV
US10196391 120 Tetrahydropyridopyrimidines and tetrahydropyridopyridines for the treatment and prophylaxis of hepatitis B virus infection Hoffmann-La Roche Inc. 06/16/192D 3D TSV
US10196374 50 1-alkyl-6-oxo-1,6-dihydropyridin-3-yl compounds and use as SGRM modulators AstraZeneca AB 06/14/192D 3D TSV
US10196354 127 4-heteroaryl substituted benzoic acid compounds as RORgammaT inhibitors and uses thereof Merck Sharp & Dohme Corp. 06/14/192D 3D TSV
US10196381 41 Benzimidazole-2-piperazine heterocyclic compound, pharmaceutical composition containing the same, preparation method and use thereof SHANGHAI HUILUN LIFE SCIENCE &TECHNOLOGY CO., LTD 06/14/192D 3D TSV
US10196353 10 Chemical compounds GlaxoSmithKline Intellectual Property (No 2) Limited 06/14/192D 3D TSV
US10196378 44 Inhibitors of BCR-ABL mutants and use thereof THE REGENTS OF THE UNIVERSITY OF MICHIGAN 06/14/192D 3D TSV
US10196365 22 Quinazoline derivative, preparation method therefor, and pharmaceutical composition and application thereof ARROMAX PHARMATECH CO., LTD. 06/14/192D 3D TSV
US10196369 103 Spirocyclic EBI2 modulators SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE 06/14/192D 3D TSV
US10196373 93 Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of STAT protein THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO; UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. 06/14/192D 3D TSV
US10196383 8 Substituted quinazoline compounds and preparation and uses thereof SUNSHINE LAKE PHARMA CO., LTD. 06/14/192D 3D TSV
US10196385 3 Tetrahydropyranyl benzamide derivatives Eli Lilly and Company 06/14/192D 3D TSV
US10196382 6 bis-Pyridazine compounds and their use in treating cancer AstraZeneca AB; Cancer Research Technology Limited 06/14/192D 3D TSV
US9724347 120 1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl)oxy)napththalen-1-yl) ureas as P38 MAP knase inhibitors Respivert, Ltd. 06/12/192D 3D TSV
US9725459 175 3-oxo-tetrahydro-furo[3,2-B]pyrrol-4(5H)-yl) derivatives I GRUNENTHAL GMBH 06/12/192D 3D TSV
US9725446 32 7-azaindole derivatives Merck Patent GmbH 06/12/192D 3D TSV
US9725465 406 Biaryl acetamide compounds and methods of use thereof Ambit Biosciences Corporation 06/12/192D 3D TSV
US10189849 50 CDK inhibitors G1 Therapeutics, Inc. 06/12/192D 3D TSV
US10195181 48 Carboxamide derivatives Novartis AG 06/12/192D 3D TSV
US9725433 164 Compounds as tyrosine kinase modulators ALLERGAN, INC. 06/12/192D 3D TSV
US10189853 42 Conformationally restricted 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as anti-tumor agents Duquesne University of the Holy Spirit 06/12/192D 3D TSV
US9725445 668 Cycloalkyl nitrile pyrazolo pyridones as Janus kinase inhibitors Merck Sharp & Dohme Corp. 06/12/192D 3D TSV
US9725426 44 Cystathionine-γ-lyase (CSE) inhibitors SOVA PHARMACEUTICALS, INC. 06/12/192D 3D TSV
US9725436 51 Cytochrome P450 inhibitors and their method of use CORTENDO AB (PUBL) 06/12/192D 3D TSV
US10189859 236 Derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine Nektar Therapeutics 06/12/192D 3D TSV
US10195178 99 GPR40 agonists in anti-diabetic drug combinations Janssen Pharmaceutica NV 06/12/192D 3D TSV
US10195201 75 Heteroaryl-pyrimidinone compounds as PDE2 inhibitors Merck Sharp & Dohme Corp. 06/12/192D 3D TSV
US9725442 422 Heterocyclic derivative having PGD2 receptor antagonist activity SHIONOGI & CO., LTD. 06/12/192D 3D TSV
US9724435 232 Highly selective sigma receptor ligands and radioligands as probes in nociceptive processing and the pathphysiological study of memory deficits and cognitive disorders THE UNIVERSITY OF MISSISSIPPI; THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 06/12/192D 3D TSV
US9725441 199 Histone demethylase inhibitors Celgene Quanticel Research, Inc. 06/12/192D 3D TSV
US9725434 62 Hydroxy-substituted orexin receptor antagonists MERCK SHARP & DOHME CORP. 06/12/192D 3D TSV
US10188639 3 Methods of treating neurological, metabolic, and other disorders using enantiopure deuterium-enriched pioglitazone DeuteRx, LLC 06/12/192D 3D TSV
US10195186 101 N-substituted-5-substituted phthalamic acids as sortilin inhibitors H. Lundbeck A/S 06/12/192D 3D TSV
US10189791 5 Pyridyl analogs of 1-(2-cyano-3,12-dioxooleana-1,9(11)dien-28-oyl) imidazole Trustees of Dartmouth College 06/12/192D 3D TSV
US9724352 7 Pyrrolo[2,1-F[1,2,4]triazine compounds, preparation methods and applications thereof Shanghai Institute of Materia Medica, Chinese Academy of Sciences; Shanghai Haihe Pharmaceutical Co., Ltd. 06/12/192D 3D TSV
US9725439 29 Quinazoline derivative and preparation method therefor CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; CENTAURUS BIOPHARMA CO., LTD.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD. 06/12/192D 3D TSV
US9725443 31 RORγ modulators Bristol-Myers Squibb Company 06/12/192D 3D TSV
US9725435 16 Substituted 4,5,6,7-tetrahydropyrazolo[4,3-c]pyridines as factor XIa inhibitors Bristol-Myers Squibb Company 06/12/192D 3D TSV
US10196346 26 Substituted acethydrazide derivative, preparation method and use thereof Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China 06/12/192D 3D TSV
US10189854 347 Substituted pyrimidine compounds GRUENENTHAL GMBH 06/12/192D 3D TSV
US9725449 371 Tricyclic compounds as anticancer agents Bristol-Myers Squibb Company 06/12/192D 3D TSV
US9725430 18 Use of small molecule inhibitors targeting EYA tyrosine phosphatase CHILDREN HOSPITAL MEDICAL CENTER 06/12/192D 3D TSV
US10189796 9 [4-(1,3,3-trimethyl-2-oxo-3,4-dihydro-1H-quinoxalin-7-yl)phenoxy]ethyloxy compound or salt thereof SANTEN PHARMACEUTICAL CO., LTD. 06/12/192D 3D TSV
US9663479 6 γ-aminobutyric acid (GABA) analogues for the treatment of pain and other disorders Novassay S.A. 06/04/192D 3D TSV
US9663475 31 2 amino-3,4-dihydrcquinazoline derivatives and the use thereof as cathepsin D inhibitors Merck Patent GmbH 06/04/192D 3D TSV
US9663502 580 2-Acylamidomethyl and sulfonylamidomethyl benzoxazine carbamates for inhibition of RORgamma activity and the treatment of disease Lycera Corporation; Merck Sharp & Dohme Corp. 06/04/192D 3D TSV
US9663522 43 3-aminocycloalkyl compounds as RORgammaT inhibitors and uses thereof Merck Sharp & Dohme Corp. 06/04/192D 3D TSV
US9663503 18 5-[[4-[[morpholin-2-yl]methylamino]-5-(trifluoromethyl)-2-pyridyl]amino]pyrazine-2-carbonitrile and therapeutic uses thereof Cancer Research Technology Limited 06/04/192D 3D TSV
US9663530 136 5-oxa-2-azabicyclo[2.2.2]OCTAN-4-yl and 5-oxa-2-azabicyclo[2.2.1]heptan-4-yl derivatives Hoffmann-La Roche Inc. 06/04/192D 3D TSV
US9663496 493 AMPK-activating heterocyclic compounds and methods for using the same Rigel Pharmaceuticals, Inc. 06/04/192D 3D TSV
US9663526 468 Aminopyrimidinyl compounds Pfizer Inc. 06/04/192D 3D TSV
US9663498 53 Aromatic heterocyclic compounds and their application in pharmaceuticals SUNSHINE LAKE PHARMA CO., LTD. 06/04/192D 3D TSV
US9663470 177 Aryl- and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International Gmbh 06/04/192D 3D TSV
US9663523 56 BET protein-inhibiting 5-aryltriazoleazepines BAYER PHARMA AKTIENGESELLSCHAFT 06/04/192D 3D TSV
US9663508 431 Biaryl acyl-sulfonamide compounds as sodium channel inhibitors Amgen Inc. 06/04/192D 3D TSV
US9663519 33 Compounds useful as inhibitors of ATR kinase Vertex Pharmaceuticals Incorporated 06/04/192D 3D TSV
US9663515 16 Dihydropyrrolopyridine inhibitors of ROR-gamma Vitae Pharmaceuticals, Inc. 06/04/192D 3D TSV
US9663527 4 Factor XIa inhibitors MERCK SHARP & DOHME CORP. 06/04/192D 3D TSV
US9663476 18 Glycine transporter-1 inhibitors AMGEN INC. 06/04/192D 3D TSV
US9663494 9 Inhibitors of bruton's tyrosine kinase Hoffmann-La Roche Inc. 06/04/192D 3D TSV
US9663543 33 Phosphonate compounds for treatment of complement mediated disorders Achillion Pharmaceuticals, Inc. 06/04/192D 3D TSV
US9663525 125 Pyrazolopyrimidinyl inhibitors of ubiquitin-activating enzyme Millennium Pharmaceuticals, Inc. 06/04/192D 3D TSV
US9663513 257 Pyrimidine PDE10 inhibitors Merck Sharp & Dohme Corp. 06/04/192D 3D TSV
US9663506 315 Quinoline carboxamide and quinoline carbonitrile derivatives as mGluR2-negative allosteric modulators, compositions, and their use Merck Sharp & Dohme Corp. 06/04/192D 3D TSV
US9663511 44 Sphingosine 1-phosphate receptor antagonists Arroyo BioSciences, LLC 06/04/192D 3D TSV
US9663528 23 Substituted 1,2,3,4,6,8,12,12a-octahydro-1,4-methanodipyrido[1,2-a:1',2'-d]pyrazines and methods for treating viral infections Gilead Sciences, Inc. 06/04/192D 3D TSV
US9663510 28 Substituted triazolopyridines and their use as TTK inhibitors BAYER PHARMA AKTIENGESELLSCHAFT; BAYER INTELLECTUAL PROPERTY GMBH 06/04/192D 3D TSV
US9663529 96 Tricyclic pyrido-carboxamide derivatives as rock inhibitors Bristol-Myers Squibb Company 06/04/192D 3D TSV
US9663463 21 3-azabicyclo[3.1.0]hexane derivative and use thereof for medical purpose SANWA KAGAKU KENKYUSHO CO., LTD.; UBE INDUSTRIES, LTD. 06/03/192D 3D TSV
US9663465 50 Acetylcholinesterase inhibitors and promnesiant serotonin 5-HT4 receptor agonists, their methods of preparation and the pharmaceutical compositions containing the same UNIVERSITE DE CAEN 06/03/192D 3D TSV
US9662330 243 Aminopyrimidine derivatives for use as modulators of kinase activity Merck Patent GmbH 06/03/192D 3D TSV
US9662339 296 Benzodioxane inhibitors of leukotriene production for combination therapy Boehringer Ingelheim International GmbH 06/03/192D 3D TSV
US9662310 68 Cyclopropanecarboxylic acid derivative DAIICHI SANKYO COMPANY, LIMITED 06/03/192D 3D TSV
US9662327 402 Phenyl and pyridinyl substituted piperidines and piperazines as inhibitors of IDH1 mutants and their use in treating cancer AGIOS PHARMACEUTICALS, INC 06/03/192D 3D TSV
US9663469 319 RORγ modulators Bristol-Myers Squibb Company 06/03/192D 3D TSV
US9663460 209 Sulfur derivatives as chemokine receptor modulators ALLERGAN, INC. 06/03/192D 3D TSV
US10189845 867 4,6-substituted-pyrazolo[1,5-a]pyrazines as janus kinase inhibitors Array BioPharma Inc. 05/29/192D 3D TSV
US9636336 248 Aminoester derivatives CHIESI FARMACEUTICI S.p.A. 05/29/192D 3D TSV
US9637499 10 Benzodioxole or benzodioxepine heterocyclic compounds as phosphodiesterase inhibitors LEO PHARMA A/S 05/29/192D 3D TSV
US9637486 28 Btk inhibitors MERCK SHARP & DOHME CORP. 05/29/192D 3D TSV
US9637484 20 Cycloalkyl acid derivative, preparation method thereof, and pharmaceutical application thereof SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.; JIANGSU HENGRUI MEDICINE CO., LTD. 05/29/192D 3D TSV
US9636335 44 Heteroaryl compounds as 5-HT4 receptor ligands SUVEN LIFE SCIENCES LIMITED 05/29/192D 3D TSV
US9637488 37 Heterocyclic compounds as inhibitors of class I PI3KS TBA 05/29/192D 3D TSV
US9637455 21 Heterocyclic sulfone RORγ modulators Bristol-Myers Squibb Company 05/29/192D 3D TSV
US9636339 64 Phenyl-dihydropyridine derivatives as aldosterone synthase inhibitors Hoffman-La Roche Inc. 05/29/192D 3D TSV
US9636338 48 Phenyl-dihydropyridine derivatives as inhibitors of aldosterone synthase Hoffmann-La Roche Inc. 05/29/192D 3D TSV
US9637487 34 Purinone compounds as kinase inhibitors PHARMACYCLICS LLC 05/29/192D 3D TSV
US10189841 544 Purinones as ubiquitin-specific protease 1 inhibitors FORMA Therapeutics, Inc. 05/29/192D 3D TSV
US9636337 315 Quinoline carboxamide and quinoline carbonitrile derivatives as mGluR2-negative allosteric modulators, compositions, and their use Merck Sharp & Dohme Corp. 05/29/192D 3D TSV
US9637472 391 Substituted 6,5-fused bicyclic heteroaryl compounds Epizyme, Inc. 05/29/192D 3D TSV
US9637496 1033 Substituted 7-azabicycles and their use as orexin receptor modulators Janssen Pharmaceutica NV 05/29/192D 3D TSV
US9637493 47 Substituted pyrrolopyrimidines as HDM2 inhibitors Merck Sharp & Dohme Corp. 05/29/192D 3D TSV
US10189840 40 Substituted tricyclic heterocyclic compounds Bristol-Myers Squibb Company 05/29/192D 3D TSV
US9636330 15 Tetrahydrocarboline derivative ONO PHARMACEUTICAL CO., LTD. 05/29/192D 3D TSV
US10189838 117 Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection Hoffman-La Roche Inc. 05/26/192D 3D TSV
US10189835 22 Derivatives and methods of treating hepatitis B infections NOVIRA THERAPEUTICS, INC. 05/26/192D 3D TSV
US10189831 182 Non-nucleoside reverse transcriptase inhibitors Merck Sharp & Dohme Corp. 05/26/192D 3D TSV
US10189836 398 Therapeutic compounds, compositions and methods of use thereof Genentech, Inc. 05/26/192D 3D TSV
US10188615 195 Alkoxy compounds for disease treatment ACUCELA INC. 05/25/192D 3D TSV
US10188653 55 Diacylglycerol acyltransferase 2 inhibitors Pfizer Inc. 05/25/192D 3D TSV
US10189819 87 Factor IXa inhibitors Merck Sharp & Dohme, Corp.; Mochida Paraceuticals Co., Ltd. 05/25/192D 3D TSV
US10189794 194 Heteroaryl compounds and uses thereof Celgene CAR LLC; Sanofi 05/25/192D 3D TSV
US10188756 189 Imaging histone deacetylases with a radiotracer using positron emission tomography The General Hospital Corporation 05/25/192D 3D TSV
US10189829 145 Inhibiting agents for Bruton's tyrosine kinase BIOGEN MA INC. 05/25/192D 3D TSV
US10189805 8 Metabolism probes for therapy and diagnosis Vanderbilt University 05/25/192D 3D TSV
US10188758 8 Organic compounds INTRA-CELLULAR THERAPIES, INC. 05/25/192D 3D TSV
US10188627 67 PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof Mitobridge, Inc.; Salk Institute for Biological Studies 05/25/192D 3D TSV
US10188667 22 Pharmaceutical compositions and methods of use of 4-pregenen-11β-17-21-triol-3,20-dione derivatives ALLERGAN, INC. 05/25/192D 3D TSV
US10188642 104 Pharmacologically active compounds Cancer Research Technology Limited 05/25/192D 3D TSV
US10189809 198 SGC stimulators Ironwood Pharmaceuticals, Inc. 05/25/192D 3D TSV
US10189788 90 Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents BAYER PHARMA AKTIENGESELLSCHAFT 05/25/192D 3D TSV
US10189816 194 Substituted pyridines as inhibitors of human immunodeficiency virus replication ViiV HEALTHCARE UK (NO. 5) LIMITED 05/25/192D 3D TSV
US10189807 7 Tetrahydrothiophene-based GABA aminotransferase inactivators Northwestern University 05/25/192D 3D TSV
US9630945 80 Autotaxin inhibitors Novartis AG 05/20/192D 3D TSV
US9630929 138 Benzenesulfonamide compounds and their use as therapeutic agents XENON PHARMACEUTICALS INC. 05/20/192D 3D TSV
US9629836 101 Compounds and compositions as inhibitors of MEK NOVARTIS AG 05/20/192D 3D TSV
US9630956 151 Compounds useful as inhibitors of ATR kinase Vertex Pharmaceuticals Incorporated 05/20/192D 3D TSV
US9630965 73 Fused amino pyridine as HSP90 inhibitors Curis, Inc. 05/20/192D 3D TSV
US9630914 86 Multitarget FAAH and COX inhibitors and therapeutical uses thereof Fondazione Istituto Italiano Di Tecnologia; The Regents of the University of California; Alma Mater Studiorum—Universita' Di Bologna 05/20/192D 3D TSV
US9630949 143 Oxoazetidine derivatives, process for the preparation thereof and use thereof in human medicine and in cosmetics GALDERMA RESEARCH & DEVELOPMENT 05/20/192D 3D TSV
US9630931 29 Pharmaceutically active pyrazine derivatives SENTINEL ONCOLOGY LIMITED 05/20/192D 3D TSV
US10183937 838 1,3-thiazol-2-yl substituted benzamides Bayer Aktiengesellschaft 05/16/192D 3D TSV
US10179123 89 2-aryl- and 2-arylalkyl-benzimidazoles as mIDH1 inhibitors BAYER PHARMA AKTIENGESELLSCHAFT 05/16/192D 3D TSV
US10174024 77 5H-pyrido[3,2-B]indole compounds as anticancer agents Bristol-Myers Squibb Company 05/16/192D 3D TSV
US10174035 234 6-morpholinyl-2-pyrazolyl-9H-purine derivatives and their use as PI3K inhibitors Daiichi Sankyo Company, Limited 05/16/192D 3D TSV
US10183940 124 Aryl and heteroaryl-fused tetrahydro-1,4-oxazepine amides as somatostatin receptor subtype 4 (SSTR4) agonists Boehringer Ingelheim International GmbH 05/16/192D 3D TSV
US10183025 206 Autotaxin inhibitors Novartis AG 05/16/192D 3D TSV
US10174049 36 Compounds as diacylglycerol acyltransferase inhibitors Glaxosmithkline LLC 05/16/192D 3D TSV
US10179761 52 Compounds, pharmaceutical composition and their use in treating neurodegenerative diseases UNIVERSITE DE LILLE 2 DROIT ET SANTE; CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU) 05/16/192D 3D TSV
US10174030 116 Cyclopropylamines as LSD1 inhibitors Incyte Corporation 05/16/192D 3D TSV
US10174037 579 Dihydropyrazolopyrimidinone compounds as PDE2 inhibitors Merck Sharp & Dohme Corp. 05/16/192D 3D TSV
US10183939 56 Fused bicyclic (hetero)aromatic compounds useful for the treatment of cancers Redx Pharma PLC 05/16/192D 3D TSV
US10174044 63 Fused pyridines as kinase inhibitors Bristol-Myers Squibb Company 05/16/192D 3D TSV
US10183938 448 Geminal substituted quinuclidine amide compounds as agonists of α-7 nicotonic acetylcholine receptors Axovant Sciences GmbH 05/16/192D 3D TSV
US10174023 22 Heterocyclic-imidazole compounds, pharmaceutical compositions thereof, preparation method therefor and use thereof SHANGHAI HUILUN LIFE SCIENCE & TECHNOLOGY CO., LTD 05/16/192D 3D TSV
US10174026 297 Histone demethylase inhibitors CELGENE QUANTICEL RESEARCH, INC. 05/16/192D 3D TSV
US10179769 211 Histone demethylase inhibitors Celgene Quanticel Research, Inc. 05/16/192D 3D TSV
US10183928 8 Inhibitors of RET BLUEPRINT MEDICINES CORPORATION 05/16/192D 3D TSV
US10179773 10 Isoxazole carboxamides as irreversible SMYD inhibitors EPIZYME, INC. 05/16/192D 3D TSV
US10183942 112 JAK kinase inhibitor compounds for treatment of respiratory disease THERAVANCE BIOPHARMA R&D IP, LLC 05/16/192D 3D TSV
US10179804 132 Melanocortin receptor-specific peptides Palatin Technologies, Inc. 05/16/192D 3D TSV
US10183954 14 Oxathiolane carboxylic acids and derivatives for the treatment and prophylaxis of virus infection Hoffmann-La Roche Inc. 05/16/192D 3D TSV
US10183913 128 Pyrazole compound SUMITOMO DAINIPPON PHARMA CO., LTD. 05/16/192D 3D TSV
US10183947 51 Pyrazole derivatives useful as 5-lipoxygenase activating protein (FLAP) inhibitors ASTRAZENECA AB 05/16/192D 3D TSV
US10174020 10 Pyridone or pyrimidone derivative, preparation method therefor and application thereof SICHUAN HAISCO PHARMACEUTICAL CO., LTD. 05/16/192D 3D TSV
US10183944 614 Pyrimido-pyridazinone compounds and methods of use thereof Asana BioSciences, LLC 05/16/192D 3D TSV
US10174040 143 Pyrrolopyrimidine compound or salt thereof and compositions containing the pyrrolopyrimidine compound or salt thereof Taiho Pharmaceutical Co., Ltd. 05/16/192D 3D TSV
US10183931 91 Rho kinase inhibitors Kadmon Corporation, LLC 05/16/192D 3D TSV
US10179791 122 Spiro-cyclic amine derivatives as S1P modulators AbbVie B.V.; AbbVie, Inc. 05/16/192D 3D TSV
US10183953 990 Substituted 2-azabicycles and their use as orexin receptor modulators Janssen Pharmaceutica NV 05/16/192D 3D TSV
US10183932 357 Substituted oxopyridine derivatives and use thereof cardiovascular disorders Bayer Pharma Aktiengesellschaft 05/16/192D 3D TSV
US10174028 1162 Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Array BioPharma Inc. 05/16/192D 3D TSV
US10174027 1162 Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors Array BioPharma Inc. 05/16/192D 3D TSV
US10183009 122 Therapeutic compounds and uses thereof GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. 05/16/192D 3D TSV
US10183946 92 Triazolo[4,5-D]pyrimidines HOFFMANN-LA ROCHE INC. 05/16/192D 3D TSV
US10183917 18 Tricyclic compounds and uses thereof in medicine SUNSHINE LAKE PHARMA CO., LTD. 05/16/192D 3D TSV
US10183021 388 sGC stimulators Ironwood Pharmaceuticals, Inc. 05/16/192D 3D TSV
US10174016 873 1,3-thiazol-2-yl substituted benzamides BEYER AKTIENGESELLSCHAFT 05/15/192D 3D TSV
US9624197 30 2-pyridylamino-4-nitrile-piperidinyl orexin receptor antagonists MERCK SHARP & DOHME CORP. 05/15/192D 3D TSV
US9624210 3 Amino-pyrimidine-containing spleen tyrosine kinase (Syk) inhibitors MERCK SHARP & DOHME CORP. 05/15/192D 3D TSV
US10173985 34 Aminoindazole derivatives as sodium channel inhibitors Almirall, S.A. 05/15/192D 3D TSV
US9624159 8 Aniline derivatives, their preparation and their therapeutic application SANOFI 05/15/192D 3D TSV
US10174013 42 Benzimidazole derivatives as kinase inhibitors SELVITA S.A. 05/15/192D 3D TSV
US10174000 62 Bicyclic-fused heteroaryl or aryl compounds as IRAK4 modulators Pfizer Inc. 05/15/192D 3D TSV
US9624235 20 Compounds and methods for inhibition of AP endonuclease-1/redox factor-1 (HAPE1) activity University of Pittsburgh—Of the Commonwealth System of Higher Education 05/15/192D 3D TSV
US9624213 207 Compounds and methods for kinase modulation, and indications therefor Plexxikon Inc. 05/15/192D 3D TSV
US9624217 159 Dihydropyrrolopyridine inhibitors of ROR-gamma Vitae Pharmaceuticals, Inc. 05/15/192D 3D TSV
US9624175 82 Fused-bicyclic aryl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors FORMA THERAPEUTICS, INC. 05/15/192D 3D TSV
US9624194 25 Heteroaryl compounds as sodium channel blockers Purdue Pharma L.P. 05/15/192D 3D TSV
US9624234 25 Heterocyclic compounds and methods for their use NOVARTIS AG 05/15/192D 3D TSV
US9624243 85 Heterocyclic compounds and methods of their use NOVARTIS AG 05/15/192D 3D TSV
US10174011 307 Heterocyclic compounds, process for preparation of the same and use thereof SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES; SUZHOU VIGONVITA LIFE SCIENCES CO., LTD.; TOPHARMAN SHANDONG CO., LTD. 05/15/192D 3D TSV
US10173996 511 Histone demethylase inhibitors Celgene Quanticel Research, Inc. 05/15/192D 3D TSV
US10174003 329 Histone demethylase inhibitors Celgene Quanticel Research, Inc. 05/15/192D 3D TSV
US9624188 12 IDO inhibitors Bristol-Myers Squibb Company 05/15/192D 3D TSV
US9624228 377 Inhibitors of ERK and methods of use Kura Oncology, Inc. 05/15/192D 3D TSV
US9624201 20 Inhibitors of bruton's tyrosine kinase HOFFMANN-LA ROCHE INC.; CHUGAI PHARMACEUTICAL CO. 05/15/192D 3D TSV
US9623028 67 Methods of treating a cancer using substituted pyrrolopyrimidine compounds, compositions thereof Signal Pharmaceuticals, LLC 05/15/192D 3D TSV
US10173988 15 N2-(3,4-dimethylphenyl)-6-((4-(p-tolyl)piperazin-1-yl)methyl)-1,3,5-triazine-2,4-diamine GLUCOX BIOTECH AB 05/15/192D 3D TSV
US9623021 24 Nuclear receptor binding agents GTX, Inc. 05/15/192D 3D TSV
US9624247 107 Pyrazolo-pyrrolidin-4-one derivatives as bet inhibitors and their use in the treatment of disease NOVARTIS AG 05/15/192D 3D TSV
US9624246 30 Pyridazinone macrocycles as IRAK inhibitors and uses thereof Merck Patent GmbH 05/15/192D 3D TSV
US10173995 7 Pyridine compounds used as PI3 kinase inhibitors Teligene Ltd. 05/15/192D 3D TSV
US9624218 112 Pyrido[2,3-d]pyrimidin-4-one compounds as tankyrase inhibitors Eli Lilly and Company 05/15/192D 3D TSV
US10174007 40 Substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors Pfizer Inc. 05/15/192D 3D TSV
US9624205 12 Substituted 6,5-fused bicyclic heteroaryl compounds Epizyme, Inc. 05/15/192D 3D TSV
US9624199 21 Substituted bipiperidinyl derivatives Bayer Pharma Aktiengesellschaft 05/15/192D 3D TSV
US10174015 92 Substituted heterocyclic derivative, preparation method and use thereof Xiamen University 05/15/192D 3D TSV
US9624198 15 Substituted piperidinyltetrahydroquinolines Bayer Pharma Aktiengesellschaft 05/15/192D 3D TSV
US10172868 103 Substituted quinazolines for inhibiting kinase activity NEUPHARMA, INC. 05/15/192D 3D TSV
US10173991 590 Sulfone amide linked benzothiazole inhibitors of endothelial lipase Bristol-Myers Squibb Company 05/15/192D 3D TSV
US9624241 574 Tricyclic heterocycles as BET protein inhibitors Incyte Corporation; Incyte Holdings Corporation 05/15/192D 3D TSV
US10173990 17 URAT1 inhibitor Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc. 05/15/192D 3D TSV
US9617246 74 Thioether-piperidinyl orexin receptor antagonists MERCK SHARP & DOHME CORP. 05/10/192D 3D TSV
US9617225 165 4,6-disubstituted aminopyrimidine derivatives have anti-HIV activity VIROSTATICS SRL 05/08/192D 3D TSV
US9617262 62 Antibacterial cyclopental[C]pyrrole substituted 3,4-dihydro-1H-[1,8]naphthyridinones Janssen Sciences Ireland UC 05/08/192D 3D TSV
US9617267 761 Compounds and methods for kinase modulation, and indications therefor Plexxikon Inc. 05/08/192D 3D TSV
US9617226 45 Fused heterocyclic or carbocyclic compounds carrying a substituted cycloaliphatic radical and use thereof for treating vasopressin-related diseases AbbVie Deutschland GmbH & Co. KG 05/08/192D 3D TSV
US9617273 122 Fused tetra or penta-cyclic dihydrodiazepinocarbazolones as PARP inhibitors BeiGene, Ltd. 05/08/192D 3D TSV
US9617259 45 Histone deacetylase inhibitors and compositions and methods of use thereof CHDI Foundation, Inc. 05/08/192D 3D TSV
US9617242 237 Histone demethylase inhibitors CELGENE QUANTICEL RESEARCH, INC. 05/08/192D 3D TSV
US9617281 8 Imidazo[2,1-b]thiazole derivatives, their preparation and use as medicaments LABORATORIES DEL DR. ESTEVE S.A. 05/08/192D 3D TSV
US9617260 34 Inhibitors of bruton's tyrosine kinase Hoffmann-La Roche Inc. 05/08/192D 3D TSV
US9617282 218 Macrocyclic compounds as IRAK4 inhibitors for the treatment of inflammatory diseases BIOGEN MA INC. 05/08/192D 3D TSV
US9617269 97 N-substituted pyrazolo [3,4-D] pyrimidine ketone compound, and preparation process and use thereof Sun Yat-Sen University; University of North Carolina at Chapel Hill 05/08/192D 3D TSV
US9617239 89 Phenoxy thiophene sulfonamides and their use as inhibitors of glucuronidase North Carolina Central University; The University of North Carolina at Chapel Hill 05/08/192D 3D TSV
US9617250 26 Pyridin-4-yl derivatives ACTELION PHARMACEUTICALS LTD. 05/08/192D 3D TSV
US9617258 611 Pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl and pyrrolo[2,3-d]pyridinyl acrylamides Pfizer Inc. 05/08/192D 3D TSV
US9617261 11 Substituted pyridinone compounds as MEK inhibitors CMG PHARMACEUTICAL CO., LTD. 05/08/192D 3D TSV
US9617271 72 Triazolo compounds Hoffmann-La Roche Inc. 05/08/192D 3D TSV
US9617272 20 Tricyclic compounds as inhibitors of immunosuppression mediated by tryptophan metabolization NewLink Genetics Corporation 05/08/192D 3D TSV
US9616063 30 1-[2-(aminomethyl)benzyl]-2-thioxo-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-ones as inhibitors of myeloperoxidase AstraZeneca AB 05/07/192D 3D TSV
US9617222 48 Alkynyl indazole derivative and use thereof SENJU PHARMACEUTICAL CO., LTD. 05/07/192D 3D TSV
US9616064 137 Rho kinase inhibitors and methods of use H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. 05/07/192D 3D TSV
US9616059 12 Substituted indazole derivatives active as kinase inhibitors NERVIANO MEDICAL SCIENCES S.R.L. 05/07/192D 3D TSV
US10172856 122 2,4-diaminopyrimidine derivatives as histamine H4 modulators Janssen Pharmaceutica NV 04/30/192D 3D TSV
US10172859 919 Arylquinazolines Merck Patent GmbH 04/30/192D 3D TSV
US9611269 84 Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as JAK inhibitors Incyte Corporation; Incyte Holdings Corporation 04/30/192D 3D TSV
US10172858 368 Combination pharmaceutical compositions and uses thereof INTELLIKINE LLC 04/30/192D 3D TSV
US9611270 21 Inhibitors of CYP17A1 UNIVERSITY OF KANSAS 04/30/192D 3D TSV
US10172837 11 Insulin sensitisers and methods of treatment Naia Metabolic, Inc. 04/30/192D 3D TSV
US9611275 61 Permeable glycosidase inhibitors and uses thereof ALECTOS THERAPEUTICS, INC.; MERCK SHARP & DOHME CORP. 04/30/192D 3D TSV
US10172843 81 Piperidine derivatives Hoffmann-La Roche Inc. 04/30/192D 3D TSV
US9611277 990 Substituted 2-azabicycles and their use as orexin receptor modulators Janssen Pharmaceutica NV 04/30/192D 3D TSV
US10172845 2116 Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Array BioPharma Inc. 04/30/192D 3D TSV
US10172851 1229 Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Array BioPharma Inc. 04/30/192D 3D TSV
US10172814 213 Substituted pyridyl-cycloalkyl-carboxylic acids, compositions containing them and medical uses thereof BAYER PHARMA AKTIENGESELLSCHAFT 04/30/192D 3D TSV
US10172864 1070 Therapeutically active compounds and their methods of use Agios Pharmaceuticals, Inc. 04/30/192D 3D TSV
US9611229 39 1,2,3-triazole-4-amine derivatives for the treatment of sigma receptor related diseases and disorders LABORATORIOS DEL DR. ESTEVE S.A. 04/29/192D 3D TSV
US9611249 35 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. 04/29/192D 3D TSV
US9611224 350 Antiproliferative benzo [B] azepin-2-ones HOFFMANN-LA ROCHE INC. 04/29/192D 3D TSV
US9610264 16 Compounds for the treatment and prevention of retroviral infections KFLP BIOTECH, LLC 04/29/192D 3D TSV
US9610299 42 Compounds for the treatment of addiction Gilead Sciences, Inc. 04/29/192D 3D TSV
US9611221 199 Histone demethylase inhibitors Celgene Quanticel Research, Inc. 04/29/192D 3D TSV
US9610322 10 Macrocyclic insulin-degrading enzyme (IDE) inhibitors and uses thereof President and Fellows of Harvard College 04/29/192D 3D TSV
US9611232 8 Oxazolidinone and imidazolidinone compounds Hoffmann-La Roche Inc. 04/29/192D 3D TSV
US9611261 846 Perfluorinated cyclopropyl fused 1,3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use Amgen Inc. 04/29/192D 3D TSV
US9611222 152 Pyridine compounds and the uses thereof Purdue Pharma L.P. 04/29/192D 3D TSV
US9611262 489 Substituted 2-azabicycles and their use as orexin receptor modulators Janssen Pharmaceutica NV 04/29/192D 3D TSV
US9611251 546 Substituted piperidine compounds and their use as orexin receptor modulators Janssen Pharmaceutica NV 04/29/192D 3D TSV
US9611259 3 Substituted pyridine derivatives useful as C-FMS kinase inhibitors Janssen Pharmaceutica NV 04/29/192D 3D TSV
US9611267 699 Substituted tricyclic compounds as FGFR inhibitors Incyte Holdings Corporation; Incyte Corporation 04/29/192D 3D TSV
US9611252 146 Therapeutic inhibitory compounds LIFESCI PHARMACEUTICALS, INC. 04/29/192D 3D TSV
US9611265 241 Tropomyosin-related kinase (TRK) inhibitors GENZYME CORPORATION 04/29/192D 3D TSV
US10167299 125 1-(3-aminopropyl) substituted cyclic amine compounds, preparation method therefor, and pharmaceutical compositions and uses thereof SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES 04/24/192D 3D TSV
US10167282 14 1-(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido [2, 3-B]pyrazin- 8-yl)oxy]phenyl]urea derivatives as RAF inhibitors for the treatment of cancer CANCER RESEARCH TECHNOLOGY LIMITED; INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (THE) 04/24/192D 3D TSV
US9605007 135 2-amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl-1,3-thiazol-4-yl amides Pfizer Inc. 04/24/192D 3D TSV
US10167261 20 2-oxo-3,4-dihydroquinolin-6-yl sulphonamide CPDS and their use as plant growth regulators THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; SYNGENTA PARTICIPATIONS AG 04/24/192D 3D TSV
US9605006 15 5-aryl-1-imino-1-oxo-[1,2,4]thiadiazines Hoffmann-La Roche Inc. 04/24/192D 3D TSV
US9605005 199 Alkynyl alcohols and methods of use Genentech, Inc. 04/24/192D 3D TSV
US10167292 172 Benzodiazepines as bromodomain inhibitors Catalyst Therapeutics Pty Ltd. 04/24/192D 3D TSV
US9605008 21 Benzyl-1H-pyrazolo[3,4-b]pyridines and use thereof BAYER PHARMA AKTIENGESELLSCHAFT 04/24/192D 3D TSV
US10167279 409 Compounds and compositions as RAF kinase inhibitors Novartis AG 04/24/192D 3D TSV
US10167276 207 Compounds and methods for inhibiting JAK Dizal (Jiangsu) Pharmaceutical Co., Ltd. 04/24/192D 3D TSV
US9604998 109 Inhibitors of the renal outer medullary potassium channel Merck Sharp & Dohme Corp. 04/24/192D 3D TSV
US9605022 39 Macrocyclic compounds for inhibition of inhibitors of apoptosis Ensemble Therapeutics Corporation 04/24/192D 3D TSV
US9605024 9 PAR4 agonist peptides Bristol-Myers Squibb Company 04/24/192D 3D TSV
US10167256 8 Psychotrophic agents and uses thereof LB PHARMACEUTICALS INC. 04/24/192D 3D TSV
US10167313 102 Selective caspase inhibitors and uses thereof Genesis Technologies Limited 04/24/192D 3D TSV
US10167285 48 Small-molecule HSP90 inhibitors Memorial Sloan Kettering Cancer Center 04/24/192D 3D TSV
US10166249 952 Substituted bicyclic compounds Bristol-Myers Squibb Company 04/24/192D 3D TSV
US10167280 108 Substituted oxopyridine derivatives BAYER PHARMA AKTIENGESELLSCHAFT 04/24/192D 3D TSV
US10167264 10 Substituted pyrimidines useful as EGFR-T790M kinase inhibitors Jiangsu Medolution Ltd 04/24/192D 3D TSV
US10167270 175 Substituted quinazoline compounds and uses thereof for modulating glucocerebrosidase activity Northwestern University 04/24/192D 3D TSV
US10167281 213 Substituted thiazole or oxazole P2X7 receptor antagonists Axxam S.P.A. 04/24/192D 3D TSV
US10166216 151 Substituted triazoles useful as Axl inhibitors Rigel Pharmaceuticals, Inc. 04/24/192D 3D TSV
US10167273 111 Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases Takeda Pharmaceutical Company Limited 04/24/192D 3D TSV
US10167296 99 Sulfoximine substituted quinazolines for pharmaceutical compositions EVOTEC INTERNATIONAL GMBH 04/24/192D 3D TSV
US10166239 241 Tropomyosin-related kinase (Trk) inhibitors Genzyme Corporation 04/24/192D 3D TSV
US10167293 76 [8-(phenylsulfonyl)-3,8-diazabicyclo[3.2.1]oct-3-yl](1H-1,2,3-triazol-4-yl)methanones BAYER PHARMA AKTIENGESELLSCHAFT 04/24/192D 3D TSV
US9603834 27 1,2- bis-sulfonamide derivatives as chemokine receptor modulators ALLERGAN, INC. 04/23/192D 3D TSV
US9604984 934 5-chloro-2-difluoromethoxyphenyl pyrazolopyrimidine compounds, compositions and methods of use thereof Genentech, Inc. 04/23/192D 3D TSV
US9604960 81 Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof Albany Molecular Research, Inc. 04/23/192D 3D TSV
US9604944 6 Arylpiperazine derivatives and methods of utilizing same REVIVA PHARMACEUTICALS, INC. 04/23/192D 3D TSV
US9603833 88 Benzene or thiophene derivative and use thereof as VAP-1 inhibitor R-Tech Ueno, Ltd. 04/23/192D 3D TSV
US9604977 516 Bicyclic thiophenylamide compounds Hoffman-La Roche Inc. 04/23/192D 3D TSV
US9604926 226 Highly selective sigma receptor radioligands THE UNIVERSITY OF MISSISSIPPI 04/23/192D 3D TSV
US9604961 509 Histone demethylase inhibitors Celgene Quanticel Research, Inc. 04/23/192D 3D TSV
US9603889 86 IAP antagonists Bristol-Myers Squibb Company 04/23/192D 3D TSV
US9604989 159 Imidazopyridazines as Akt kinase inhibitors BAYER INTELLECTUAL PROPERTY GMBH; BAYER PHARMA AKTIENGESELLSCHAFT 04/23/192D 3D TSV
US9603854 119 Indolizine compounds, a process for their preparation and pharmaceutical compositions containing them LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD 04/23/192D 3D TSV
US9604931 24 Nuclear receptor binding agents GTx, Inc.; THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 04/23/192D 3D TSV
US9604982 678 P2X7 modulators Janssen Pharmaceutica NV 04/23/192D 3D TSV
US9603836 28 Pyrrolidine-2, 5-dione derivatives, pharmaceutical compositions and methods for use as IDO1 inhibitors ITEOS THERAPEUTICS 04/23/192D 3D TSV
US9603819 13 Substituted aminobutyric derivatives as neprilysin inhibitors NOVARTIS AG 04/23/192D 3D TSV
US9604945 7 Sydnonimines-specific dopamine reuptake inhibitors and their use in treating dopamine related disorders Caliper Life Sciences, Inc. 04/23/192D 3D TSV
US10166226 9 CGRP receptor antagonists Heptares Therapeutics Limited 04/11/192D 3D TSV
US10166229 10 Compounds and methods for the treatment of cancer The Board of Trustees of the University of Illinois 04/11/192D 3D TSV
US10155763 7 2-pyridyl substituted imidazoles as ALK5 and/or ALK4 inhibitors TIUMBIO CO., LTD. 04/10/192D 3D TSV
US10155750 76 Amidoethyl azole orexin receptor antagonists Merck Sharp & Dohme Corp. 04/10/192D 3D TSV
US10155760 237 Biaryl kinase inhibitors Bristol-Myers Squibb Company 04/10/192D 3D TSV
US10155765 66 Carboxamide inhibitors of IRAK4 activity Merck Sharp & Dohme Corp. 04/10/192D 3D TSV
US10155769 91 Fused azaheterocyclic compounds and their use as AMPA receptor modulators Janssen Pharmaceutica NV 04/10/192D 3D TSV
US10155768 520 Fused pyrimidine compound or salt thereof Taiho Pharmaceutical Co., Ltd. 04/10/192D 3D TSV
US10155752 16 Indazoles and use thereof Purdue Pharma L.P. 04/10/192D 3D TSV
US10155733 27 N-aralkylcarbonyl-piperazine and -homopiperazine compounds and personal care compositions comprising the same Conopco, Inc. 04/10/192D 3D TSV
US10155731 131 Nitrogen-containing saturated heterocyclic compound MITSUBISHI TANABE PHARMA CORPORATION; SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. 04/10/192D 3D TSV
US10155751 81 Pyrazolyl-substituted heteroaryls and their use as medicaments Boehringer Ingelheim International GmbH 04/10/192D 3D TSV
US10155732 5 Ribonucleotide reductase inhibitors and methods of use City of Hope 04/10/192D 3D TSV
US10155972 10 Screening method Iomet Pharma Ltd. 04/10/192D 3D TSV
US10166214 284 Somatostatin receptor subtype 4 (SSTR4) agonists Centrexion Therapeutics Corporation 04/10/192D 3D TSV
US10155775 8 Substituted amino six-membered saturated heteroalicycles as long-acting DPP-IV inhibitors Centaurus Biopharma Co., Ltd.; Chia Tai Tianqing Pharmaceutical Co., Ltd.; Lianyungang Runzhong Pharmaceutical Co., Ltd. 04/10/192D 3D TSV
US10155764 114 Therapeutic compounds and uses thereof GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC. 04/10/192D 3D TSV
US10150759 3 1,4-pyridone bicycic heteroaryl compounds Epizyme, Inc. 04/09/192D 3D TSV
US10150755 127 ASK1 inhibitor compounds and uses thereof SEAL ROCK THERAPEUTICS, INC. 04/09/192D 3D TSV
US9657003 40 Androgen receptor modulating compounds ORION CORPORATION 04/09/192D 3D TSV
US10155722 20 Antitumor compound targeting IDH2 mutation and method of use thereof Chia Tai Tianqing Pharmaceutical Group Co., Ltd.; Lianyungang Runzhong Pharmaceutical Co., Ltd.; Centaurus Biopharma Co., Ltd. 04/09/192D 3D TSV
US10155002 334 Aryl- or heteroaryl-substituted benzene compounds Epizyme, Inc. 04/09/192D 3D TSV
US9657001 65 Compounds and uses ASTRAZENECA AB 04/09/192D 3D TSV
US10150760 390 Compounds for use in preparing heterocyclic triazole agonists of the APJ receptor AMGEN INC. 04/09/192D 3D TSV
US9656996 17 Fused heterocyclic compound, preparation method therefor, pharmaceutical composition, and uses thereof SHANGHAI YINGLI PHARMACEUTICAL CO., LTD. 04/09/192D 3D TSV
US9657009 168 Heteroaryl substituted pyridyl compounds useful as kinase modulators Bristol-Myers Squibb Company 04/09/192D 3D TSV
US10150763 76 Histone deacetylase inhibitors and their use in therapy Karus Therapeutics Limited 04/09/192D 3D TSV
US9656988 1351 Inhibitors of Bruton's tyrosine kinase PHARMACYCLICS LLC 04/09/192D 3D TSV
US9656991 121 Inhibitors of glutaminyl cyclase PROBIODRUG AG 04/09/192D 3D TSV
US10150765 843 P2X7 modulators Janssen Pharmaceutica NV 04/09/192D 3D TSV
US10150766 102 P2X7 modulators Janssen Pharmaceutica NV 04/09/192D 3D TSV
US10150758 30 PRMT5 inhibitors and uses thereof Epizyme, Inc. 04/09/192D 3D TSV
US10155727 217 Pyrazoles JANSSEN PHARMACEUTICALS, INC. 04/09/192D 3D TSV
US9657007 36 Substituted aminopyrimidine compounds and methods of use CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD. 04/09/192D 3D TSV
US10150764 139 Substituted benzene compounds Epizyme, Inc. 04/09/192D 3D TSV
US9657015 73 Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity Boehringer Ingelheim International GmbH 04/09/192D 3D TSV
US10150787 10 TC-PTP inhibitors as APC activators for immunotherapy TBA 04/09/192D 3D TSV
US9657033 112 Tetrahydronaphthyridine and related bicyclic compounds for inhibition of RORγ activity and the treatment of disease Lycera Corporation; Merck Sharp & Dohme Corp. 04/09/192D 3D TSV
US10150767 46 Therapeutic compounds and uses thereof Genentech, Inc.; Constellation Pharmaceuticals Inc. 04/09/192D 3D TSV
US10150762 178 Trifluoromethyl alcohols as modulators of RORγt Janssen Pharmaceutica, NV 04/09/192D 3D TSV
US9656975 20 Bicyclo[3.2.1]octyl amide derivatives and uses of same H. Lundbeck A/S 04/08/192D 3D TSV
US9655879 188 Heteroarylcarboxylic acid ester derivative EA Pharma Co., Ltd. 04/08/192D 3D TSV
US9656961 158 Methods for treating depressive symptoms ALKERMES PHARMA IRELAND LIMITED 04/08/192D 3D TSV
US9656968 122 Pyrimidines as sodium channel blockers TBA 04/08/192D 3D TSV
US9656955 808 Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG 04/08/192D 3D TSV
US9656962 87 Ring-contracted morphinans and the use thereof Purdue Pharma L.P. 04/08/192D 3D TSV
US9656959 90 Substituted pyridines as sodium channel blockers Purdue Pharma L.P. 04/08/192D 3D TSV
US9649308 246 Benzamide-containing compounds and their use in the treatment of pain H. Lundbeck A/S 04/03/192D 3D TSV
US9650377 368 Diazepinone derivatives Novartis AG 04/03/192D 3D TSV
US9650366 16 Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitors ALLERGAN, INC. 04/03/192D 3D TSV
US9650362 20 Inhibitors PROBIODRUG AG 04/03/192D 3D TSV
US9650336 11 Mono-fluoro beta-secretase inhibitors ASTRAZENECA AB 04/03/192D 3D TSV
US9650358 339 Pyridine CDK9 kinase inhibitors AbbVie Inc. 04/03/192D 3D TSV
US9650371 37 Sulfur-containing heterocyclic derivative having beta secretase inhibitory activity Shionogi & Co., Ltd. 04/03/192D 3D TSV
US9649309 1394 Therapeutic uses of selected pyrimidine compounds with anti-Mer tyrosine kinase activity The University of North Carolina at Chapel Hill 04/03/192D 3D TSV
US10150740 15 6,7-dihydropyrido[2,1-A]phthalazin-2-ones for the treatment and prophylaxis of hepatitis B virus infection Hoffmann-La Roche Inc. 03/31/192D 3D TSV
US10150728 704 Alkylene derivatives SHIONOGI & CO., LTD. 03/31/192D 3D TSV
US10144746 350 Bridged bicyclic kallikrein inhibitors Global Blood Therapeutics, Inc. 03/31/192D 3D TSV
US10150743 28 Carboxylic acid compounds Sumitomo Dainippon Pharma Co., Ltd. 03/31/192D 3D TSV
US10149839 156 Chemical compounds AstraZeneca AB 03/31/192D 3D TSV
US10149841 6 Compound of 3-hydroxyl pyridine, preparation method thereof and pharmaceutical use thereof SHENYANG SUNSHINE PHARMACEUTICAL CO. LTD. 03/31/192D 3D TSV
US10150747 65 Compounds for the treatment of hepatitis C Bristol-Myers Squibb Company 03/31/192D 3D TSV
US10149835 7 Isoxazole derivatives as FXR agonists and methods of use thereof Elmore Patent Law Group, P.C. 03/31/192D 3D TSV
US10149840 3 OCT3 activity inhibitor containing imidazopyridine derivative as active component, and OCT3 detection agent SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. 03/31/192D 3D TSV
US10150751 82 Pyrrolidine orexin receptor antagonists Merck Sharp & Dohme Corp. 03/31/192D 3D TSV
US10143681 183 Factor XIa inhibitors Merck Sharp & Dohme Corp. 03/30/192D 3D TSV
US10138245 14 Fused triazole derivatives as phosphodiesterase 10A inhibitors CELON PHARMA S.A. 03/30/192D 3D TSV
US10143668 5 Hydroxy-substituted amino and ammonium derivatives and their medical use GRI BIO, INC. 03/30/192D 3D TSV
US10138253 38 Imidazopyridine macrocycles as inhibitors of human immunodeficiency virus replication ViiV HEALTHCARE UK (NO.5) LIMITED 03/30/192D 3D TSV
US10143746 28 Immunomodulators Bristol-Myers Squibb Company 03/30/192D 3D TSV
US10144729 8 Isoxazole analogs as FXR agonists and methods of use thereof ENANTA PHARMACEUTICALS, INC. 03/30/192D 3D TSV
US10143704 1 Methods for treating cancer Epizyme, Inc. 03/30/192D 3D TSV
USRE47141 78 Methods of treating fibrosis, cancer and vascular injuries EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION 03/30/192D 3D TSV
US10144731 519 Nrf2 regulators GlaxoSmithKline Intellectual Property Development Limited; Astex Therapeutics, Ltd 03/30/192D 3D TSV
US10144715 925 Piperazine derivatives as liver X receptor modulators Vitae Pharmaceuticals, Inc. 03/30/192D 3D TSV
US10144738 148 Pyrazolo[1,5-A]PYRAZIN-4-YL derivatives Pfizer Inc. 03/30/192D 3D TSV
US10138242 229 Pyrazolopyridine derivatives and their use in therapy TBA 03/30/192D 3D TSV
US10143695 130 Pyrrolobenzodiazepines and conjugates thereof Mersana Therapeutics, Inc. 03/30/192D 3D TSV
US10144742 520 Quinoxaline compounds and uses thereof Millennium Pharmaceuticals, Inc. 03/30/192D 3D TSV
US10144734 2116 Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Array BioPharma Inc. 03/30/192D 3D TSV
US10138249 20 Triazolopyridines and triazolopyrazines as LSD1 inhibitors Incyte Corporation 03/30/192D 3D TSV
US10137110 81 1-cyclohexyl-2-phenylaminobenzimidazoles as mIDH1 inhibitors for the treatment of tumors Bayer Pharma Aktiengesellschaft 03/29/192D 3D TSV
US9597318 7 2-oxothiazole compounds and method of using same for chronic inflammatory disorders Avexxin AS 03/29/192D 3D TSV
US9598446 65 Amino compounds for treatment of complement mediated disorders ACHILLION PHARMACEUTICALS, INC. 03/29/192D 3D TSV
US10138212 111 Aminoquinazoline compounds as A2A antagonist Merck Sharp & Dohme Corp. 03/29/192D 3D TSV
US9598407 41 Antibacterial piperidinyl substituted 3,4-dihydro-1H-[1,8]naphthyridinones Janssen Sciences Ireland UC 03/29/192D 3D TSV
US10137202 11 Antibody-drug conjugates and immunotoxins Oncomatryx Biopharma, S.L. 03/29/192D 3D TSV
US10138230 125 Autotaxin inhibitors Cancer Research Technology Limited 03/29/192D 3D TSV
US9597333 160 Benzazepine dicarboxamide compounds Hoffmann-La Roche Inc. 03/29/192D 3D TSV
US10138226 44 Benzimidazol-2-amines as MIDH1 inhibitors Bayer Pharma Aktiengesellschaft 03/29/192D 3D TSV
US9597326 26 Benzonapthyridine compositions and uses thereof GlaxoSmithKline Biologicals SA; U.S. Army Medical Research and Materiel Command 03/29/192D 3D TSV
US10131670 108 Bicyclic heteroaryl derivatives as CFTR potentiators CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. 03/29/192D 3D TSV
US10131663 194 Chemical compounds AstraZeneca AB 03/29/192D 3D TSV
US9598415 265 Compounds as modulators of RORγ Boehringer Ingelheim International GmbH 03/29/192D 3D TSV
US9598431 15 Compounds useful for inhibiting ROR-gamma-t Eli Lilly and Company 03/29/192D 3D TSV
US10138240 2 Crystal of 5-hydroxy-4-(trifluoromethyl)pyrazolopyridine derivative Daiichi Sankyo Company, Limited 03/29/192D 3D TSV
US9597330 60 Drugs for treating respiratory diseases Daiichi Sankyo Company, Limited 03/29/192D 3D TSV
US10138236 66 Factor xia-inhibiting pyridobenzazepine and pyridobenzazocine derivatives BAYER PHARMA AKTIENGESELLSCHAFT 03/29/192D 3D TSV
US10138229 156 Heteroaromatic compounds as BTK inhibitors Boehringer Ingelheim International GmbH 03/29/192D 3D TSV
US9598421 372 Imidazopyridazine compounds Pfizer Inc. 03/29/192D 3D TSV
US9597310 65 Indanyloxydihydrobenzofuranylacetic acids Boehringer Ingelheim International GmbH 03/29/192D 3D TSV
US9598440 159 Inhibitors of IRAK4 activity MERCK SHARP & DOHME CORP. 03/29/192D 3D TSV
US10131664 178 Inhibitors of lysine specific demethylase-1 Celgene Quanticel Research, Inc. 03/29/192D 3D TSV
US10138228 4 Isoxazole derivatives as FXR agonists and methods of use therof ENANTA PHARMACEUTICALS, INC. 03/29/192D 3D TSV
US10137122 244 Kinase inhibitors and methods of use thereof The Broad Institute, Inc.; Dana-Farber Cancer Institute, Inc.; The General Hospital Corporation 03/29/192D 3D TSV
US9598426 8 Organic compounds INTRA-CELLULAR THERAPIES, INC. 03/29/192D 3D TSV
US9598447 72 Phosphorus-substituted quinoxaline-type piperidine compounds and uses thereof Purdue Pharma L.P. 03/29/192D 3D TSV
US10131673 42 Piperidine substituted tricyclic pyrazolo[1,5-a]pyrimidine derivatives with inhibitory activity on the replication of the respiratory syncytial virus (RSV) Janssen Sciences Ireland UC 03/29/192D 3D TSV
US9598370 55 Prolyl hydroxylase inhibitors and methods of use Akebia Therapeutics, Inc. 03/29/192D 3D TSV
US9598381 18 SMYD2 inhibitors AbbVie Inc. 03/29/192D 3D TSV
US9598410 68 Substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-C]pyridines, their use as medicament, and pharmaceutical preparations comprising them SANOFI 03/29/192D 3D TSV
US9598423 827 Substituted 4,5,6,7-tetrahydropyrazolo[1,5-A]pyrazine derivatives as casein kinase 1 D/E inhibitors Bristol-Myers Squibb Company 03/29/192D 3D TSV
US10138222 122 Substituted benzamides as RIPK2 inhibitors Boehringer Ingelheim International GmbH 03/29/192D 3D TSV
US10138241 97 Substituted benzamides as RIPK2 inhibitors Boehringer Ingelheim International GmbH 03/29/192D 3D TSV
US9598411 172 Substituted benzimidazole-type piperidine compounds and uses thereof Purdue Pharma L.P. 03/29/192D 3D TSV
US9598416 159 Substituted benzothienyl-pyrrolotriazines and uses thereof in the treatment cancer BAYER INTELLECTUAL PROPERTY GMBH 03/29/192D 3D TSV
US9598436 18 Substituted bicyclic heteroaryl compounds Bristol-Myers Squibb Company 03/29/192D 3D TSV
US9598401 63 Substituted heteroaryl compounds and methods of use thereof SUNSHINE LAKE PHARMA CO., LTD. 03/29/192D 3D TSV
US9597317 74 Substituted indazole derivatives active as kinase inhibitiors NERVIANO MEDICAL SCIENCES S.R.L. 03/29/192D 3D TSV
US10137124 1229 Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors Array BioPharma Inc. 03/29/192D 3D TSV
US10131667 699 Substituted tricyclic compounds as FGFR inhibitors Incyte Corporation 03/29/192D 3D TSV
US9598396 39 Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as PARP and tubulin polymerization inhibitors Janssen Pharmaceutica NV 03/29/192D 3D TSV
US9598405 52 Thiazole-substituted aminopyridines as spleen tyrosine kinase inhibitors Merck Sharp & Dohme Corp. 03/29/192D 3D TSV
US10137210 9 Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition The University of Pittsburgh—Of the Commonwealth System of Higher Education 03/29/192D 3D TSV
US10131675 153 Tricyclic DLK inhibitors and uses thereof Genentech, Inc. 03/29/192D 3D TSV
US9598387 260 Urea and amide derivatives of aminoalkylpiperazines and use thereof Southern Research Institute 03/29/192D 3D TSV
US10131692 88 Vasopressin-2 receptor agonists Ferring B.V. 03/29/192D 3D TSV
US10130619 70 Amido thiadiazole derivatives as NADPH oxidase inhibitors GENKYOTEX SUISSE SA 03/28/192D 3D TSV
US10131658 37 Anti-alphavbeta1 integrin compounds and methods The Regents of the University of California 03/28/192D 3D TSV
US10131645 33 Benzofurans substituted with primary benzamide as HCV inhibitors Bristol-Myers Squibb Company 03/28/192D 3D TSV
US10130617 18 Chemical compounds AstraZeneca AB 03/28/192D 3D TSV
US10130633 700 Compounds BAYER PHARMA AKTIENGESELLSCHAFT 03/28/192D 3D TSV
US10130622 11 Compounds for treatment of cystic fibrosis AbbVie S.á.r.l.; Galapagos NV 03/28/192D 3D TSV
US10130642 65 Neprilysin inhibitors THERAVANCE BIOPHARMA R&D IP, LLC 03/28/192D 3D TSV
US10131648 98 Substituted benzothiophenyl derivatives as GPR40 agonists for the treatment of type II diabetes Janssen Pharmaceutica NV 03/28/192D 3D TSV
US10131651 13 [7,6]-fused bicyclic antidiabetic compounds Merck Sharp & Dohme Corp. 03/28/192D 3D TSV
US9593097 435 Axl inhibitors Pfizer Inc. 03/15/192D 3D TSV
US9593099 22 Compounds and compositions as protein kinase inhibitors Array BioPharma, Inc. 03/15/192D 3D TSV
US9593100 23 Compounds and compositions as protein kinase inhibitors Array BioPharma, Inc. 03/15/192D 3D TSV
US9593127 20 Heterocyclylalkyne derivatives and their use as modulators of mGluR5 receptors RECORDATI IRELAND LTD. 03/15/192D 3D TSV
US9593123 194 Triazolo[4,5-D]pyrimidine derivatives Hoffmann-La Roche Inc. 03/15/192D 3D TSV
US9592235 219 Aminoquinazoline and pyridopyrimidine derivatives Genentech, Inc. 03/14/192D 3D TSV
US9593105 223 Cyclic amines H. Lundbeck A/S 03/14/192D 3D TSV
US9593110 201 Neprilysin inhibitors Theravence Biopharma R&D IP, LLC 03/14/192D 3D TSV
US9592230 125 Substituted imidazoles as PDE10A inhibitors H. Lundbeck A/S 03/14/192D 3D TSV
US10125145 31 5-HT3 receptor antagonists Takeda Pharmaceutical Company Limited 03/12/192D 3D TSV
US10125150 26 Crystalline forms of a PI3K inhibitor Incyte Corporation 03/12/192D 3D TSV
US9593113 85 Imide and acylurea derivatives as modulators of the glucocorticoid receptor Bristol-Myers Squibb Company 03/12/192D 3D TSV
US9593121 14 Indole substituted pyrrolopyrimidinyl inhibitors of Uba6 Millennium Pharmaceuticals, Inc. 03/12/192D 3D TSV
US9593129 497 Piperidinone derivatives as MDM2 inhibitors for the treatment of cancer Amgen, Inc. 03/12/192D 3D TSV
US10125148 28 Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication ViiV HEALTHCARE UK (NO. 5) LIMITED 03/12/192D 3D TSV
US10125097 18 1- [1-(benzoyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonitrile derivatives UNIVERSITAT DE BARCELONA; FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA); IPROTEOS S.L. 03/11/192D 3D TSV
US10125111 99 Benzofuran compounds for the treatment of hepatitis C Bristol-Myers Squibb Company 03/11/192D 3D TSV
US10125137 10 Benzofurans substituted with bicyclic secondary benzamide as HCV inhibitors Bristol-Myers Squibb Company 03/11/192D 3D TSV
US10124009 14 Bromodomain inhibitors Tensha Therapeutics, Inc. 03/11/192D 3D TSV
US10125135 51 Chemical compounds AstraZeneca AB 03/11/192D 3D TSV
US10123995 32 Factor XIa inhibitors Merck Sharp & Dohme Corp. 03/11/192D 3D TSV
US10125118 458 Heteroaryl compounds and their use as therapeutic drugs Dong-A Socio Holdings Co., Ltd. 03/11/192D 3D TSV
US10117875 20 Immune system modulators JANUS BIOTHERAPEUTICS, INC. 03/11/192D 3D TSV
US10125101 123 Indanylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof Boehringer Ingelheim International GmbH 03/11/192D 3D TSV
US10112968 7 Inhibitors of protein methyltransferase DOT1L and methods of use thereof Epizyme, Inc. 03/11/192D 3D TSV
US10112955 73 Isoindoline, azaisoindoline, dihydroindenone and dihydroazaindenone inhibitors of Mnk1 and Mnk2 eFFECTOR Therapeutics, Inc. 03/11/192D 3D TSV
US10118894 7 Isoindolinone derivatives useful as antiviral agents ViiV HEALTHCARE UK LIMITED 03/11/192D 3D TSV
US10118915 563 Kappa opioid ligands The Scripps Research Institute 03/11/192D 3D TSV
US10125100 197 Kinase inhibitors Topivert Pharma Limited 03/11/192D 3D TSV
US10125125 58 N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors Active Biotech AB 03/11/192D 3D TSV
US10123984 50 Neprilysin inhibitors THERAVANCE BIOPHARMA R&D IP, LLC 03/11/192D 3D TSV
US10118929 6 Nonanoic and decanoic acid derivatives and uses thereof SciFluor Life Sciences, Inc. 03/11/192D 3D TSV
US10118918 49 PRMT5 inhibitors and uses thereof Epizyme, Inc. 03/11/192D 3D TSV
US10118930 465 Piperidinylpyrazolopyrimidinones and their use BAYER PHARMA AKTIENGESELLSCHAFT 03/11/192D 3D TSV
US10117858 15 Pyridine and pyrazine derivative for the treatment of CF Novartis AG 03/11/192D 3D TSV
US10125144 60 Rho kinase inhibitors KADMON CORPORATION, LLC 03/11/192D 3D TSV
US10118902 223 Small molecule agonists of neurotensin receptor 1 SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE 03/11/192D 3D TSV
US10117864 67 Substituted N-bicyclo-2-aryl-quinolin-4-carboxamides and use thereof BAYER PHARMA AKTIENGESELLSCHAFT 03/11/192D 3D TSV
US10125133 13 Substituted [1,2,4]triazolo[1,5-a]pyridines and substituted [1,2,4]triazolo[1,5-a]pyrazines as LSD1 inhibitors Incyte Corporation 03/11/192D 3D TSV
US10117944 14 Targeted therapeutics MADRIGAL PHARMACEUTICALS, INC. 03/11/192D 3D TSV
US10124003 52 Therapeutic agent for FGFR inhibitor-resistant cancer Taiho Pharmaceutical Co., Ltd. 03/11/192D 3D TSV
US10112941 441 Tricyclic compounds as anticancer agents Bristol-Myers Squibb Company 03/11/192D 3D TSV
US10111866 2 Compounds as rearranged during transfection (RET) inhibitors GlaxoSmithKline Intellectual Property Development Limited 03/10/192D 3D TSV
US10112934 40 (Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles Centrexion Therapeutics Corporation 03/04/192D 3D TSV
US10112931 783 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH NOVARTIS AG 03/04/192D 3D TSV
US10112932 62 Benzoxazepin oxazolidinone compounds and methods of use Genentech, Inc. 03/04/192D 3D TSV
US10112944 41 Heterocyclic compounds useful as inhibitors of TNF Bristol-Myers Squibb Company 03/04/192D 3D TSV
US10112940 116 Histone demethylase inhibitors Celgene Quanticel Research, Inc. 03/04/192D 3D TSV
US10112935 516 Indazolyl thiadiazolamines and related compounds for inhibition of Rho-associated protein kinase and the treatment of disease Lycera Corporation 03/04/192D 3D TSV
US10112928 32 Inhibitors of SYK HOFFMANN-LA ROCHE INC. 03/04/192D 3D TSV
US10112929 379 Lactams as inhibitors of rock Bristol-Myers Squibb Company 03/04/192D 3D TSV
US10112937 1877 P2X7 modulators and methods of use Janssen Pharmaceutica NV 03/04/192D 3D TSV
US10112950 116 Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors Incyte Corporation 03/04/192D 3D TSV
US10112942 1229 Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Array BioPharma Inc. 03/04/192D 3D TSV
US10112939 112 Tied-back benzamide derivatives as potent rock inhibitors Bristol-Myers Squibb Company 03/04/192D 3D TSV
US9586925 22 1-(dimethylamino)ethyl-substituted 6H-benzo[C]chromen-6-ones against senile dementia NOBEL ILAÇ SANAYII VE TICARET A.S. 03/02/192D 3D TSV
US9586950 104 2-pyridyloxy-3-ester-4-nitrile orexin receptor antagonists MERCK SHARP & DOHME CORP. 03/02/192D 3D TSV
US10112926 1455 Amino pyridine derivatives as phosphatidylinositol 3-kinase inhibitors Novartis AG 03/02/192D 3D TSV
US9586945 38 Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. 03/02/192D 3D TSV
US9586942 17 Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. 03/02/192D 3D TSV
US10112895 14 Antivirals against molluscum contagiosum virus The Trustees of the University of Pennsylvania 03/02/192D 3D TSV
US9586949 157 Aza-heteroaryl compounds as PI3K-gamma inhibitors Incyte Corporation 03/02/192D 3D TSV
US9586962 903 Disubstituted octahydropyrrolo [3,4-C] pyrroles as orexin receptor modulators Janssen Pharmaceutica NV 03/02/192D 3D TSV
US9585879 28 Heterocyclic GSK-3 allosteric modulators Consejo Superior de Investigaciones Cientificas (CSIC) 03/02/192D 3D TSV
US9586970 27 Imidazole derivatives Hoffmann-La Roche Inc. 03/02/192D 3D TSV
US10112922 40 Inhibitor of bruton's tyrosine kinase Centaurus BioPharma Co., Ltd. 03/02/192D 3D TSV
US9586948 51 Inhibitors of IRAK4 activity MERCK SHARP & DOHME CORP. 03/02/192D 3D TSV
US10112899 326 Isoindoline derivatives for use in the treatment of a viral infection ViiV HEALTHCARE UK LIMITED 03/02/192D 3D TSV
US9586965 16 Pyrrolo[2,3-d]pyrimidine compounds as inhibitors of protein kinases ACEA BIOSCIENCES INC. 03/02/192D 3D TSV
US9586900 121 Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists Bristol-Myers Squibb Company 03/02/192D 3D TSV
US10111875 18 Pyrrolopyrimidine compounds and uses thereof HUTCHINSON MEDIPHARMA LIMITED 03/02/192D 3D TSV
US10112911 75 Substituted cyanoguanidines as oral anti-virals ABBVIE INC. 03/02/192D 3D TSV
US10112907 52 Substituted indazoles for treating tendon and/or ligament injuries NOVARTIS AG 03/02/192D 3D TSV
US9585881 56 Substituted pyrrolidines as factor XIa inhibitors for the treatment thromboembolic diseases ONO PHARMACEUTICAL CO., LTD. 03/02/192D 3D TSV
US9586959 169 Substituted tricyclic heterocycles as histamine 4 receptor inhibitors C&C RESEARCH LABORATORIES 03/02/192D 3D TSV
US10106550 6 Aza-phenalene-3-ketone derivative, preparation method thereof, and its application as PARP inhibitor SUZHOU KANGRUN PHARMACEUTICALS INC. 02/24/192D 3D TSV
US10106522 12 Benzimidazole derivatives as antihistamine agents Faes Farma, S.A. 02/24/192D 3D TSV
US10106552 43 Compounds inhibiting eukaryotic elongation factor 2 kinase activity Longevica Pharmaceuticals, Inc. 02/24/192D 3D TSV
US10106521 18 Eckol derivatives, methods of synthesis and uses thereof Phloronol, Inc. 02/24/192D 3D TSV
US10106571 23 HCV polymerase inhibitors MEDIVIR AB 02/24/192D 3D TSV
US10106535 45 Histone deacetylase inhibitors and compositions and methods of use thereof CHDI FOUNDATION, INC. 02/24/192D 3D TSV
US10106534 274 Histone demethylase inhibitors Celgene Quanticel Research, Inc. 02/24/192D 3D TSV
US10106527 488 Isoquinolin-3-yl carboxamides and preparation and use thereof Samumed, LLC 02/24/192D 3D TSV
US10106501 428 Nuclear receptor modulators AbbVie Inc. 02/24/192D 3D TSV
US10106557 26 Preparation method for benzoxazoleoxazine ketone compound and intermediate and crystal form thereof NORTH CHINA PHARMACEUTICAL NEW DRUG R&D CO., LTD. 02/24/192D 3D TSV
US10106504 83 Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication ViiV HEALTHCARE UK (NO.5) LIMITED 02/24/192D 3D TSV
US10106508 94 Quinazoline heterocyclic compound as EGFR kinase inhibitor and preparation and application thereof BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED 02/24/192D 3D TSV
US10106553 70 Substituted benzothiophenyl derivatives as GPR40 agonists for the treatment of type II diabetes Janssen Pharmaceutica NV 02/24/192D 3D TSV
US10106510 60 Substituted isoxazoles for treating cancer EPIZYME, INC. 02/24/192D 3D TSV
US10106559 152 Substituted tetrahydrocarbazole and carbazole carboxamide compounds Bristol-Myers Squibb Company 02/24/192D 3D TSV
US10100045 36 3-aryl-2H-pyrazolo[4,3-b]pyridine compounds and their use as AMPA receptor modulators Janssen Pharmaceutica NV 02/21/192D 3D TSV
US10100030 25 Carboxymethyl piperidine derivative KISSEI PHARMACEUTICAL CO., LTD. 02/21/192D 3D TSV
US10100051 14 Compound of 5-hydroxyl-1,7-naphthyridine substituted by aryloxy or heteroaryloxy, preparation method thereof and pharmaceutical use thereof SHENYANG SUNSHINE PHARMACEUTICAL CO. LTD. 02/21/192D 3D TSV
US10100058 717 Fused heterocyclic compounds as CaM kinase inhibitors Gilead Sciences, Inc. 02/21/192D 3D TSV
US10100048 7 Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors ABBVIE DEUTSCHLAND GMBH & CO. KG 02/21/192D 3D TSV
US10100057 199 Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same SK BIOPHARMACEUTICALS CO., LTD. 02/21/192D 3D TSV
US10100046 31 Inhibitors of lysine specific demethylase-1 CELGENE QUANTICEL RESEARCH, INC. 02/21/192D 3D TSV
US10100049 112 JAK kinase inhibitor compounds for treatment of respiratory disease THERAVANCE BIOPHARMA R&D IP, LLC 02/21/192D 3D TSV
US10100019 177 N2-(2-methoxyphenyl)pyrimidine derivative, method for preparing same, and pharmaceutical composition for cancer prevention or treatment containing same as active ingredient Korea Research Institute of Chemical Technology 02/21/192D 3D TSV
US10105349 6 Organic compounds INTRA-CELLULAR THERAPIES, INC. 02/21/192D 3D TSV
US10105367 304 Therapeutic thiophene-, furan-, and pyridine-fused azolopyrimidin-5-(6h)-ones DART NEUROSCIENCE (CAYMAN) LTD. 02/21/192D 3D TSV
US9580437 709 Triazolopyrimidine compounds and uses thereof Novartis AG 02/21/192D 3D TSV
US10100042 12 [5,6]—fused bicyclic antidiabetic compounds Merck Sharp & Dohme Corp. 02/21/192D 3D TSV
US9580418 156 Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors Incyte Corporation 02/19/192D 3D TSV
US9580423 200 Bicyclic heterocycles as FGFR4 inhibitors Incyte Corporation 02/19/192D 3D TSV
US9580396 112 C6-spiro iminothiadiazine dioxides as BACE inhibitors, compositions, and their use Merck Sharp & Dohme Corp. 02/19/192D 3D TSV
US9580449 298 Compositions and methods for the production of pyrimidine and pyridine compounds with BTK inhibitory activity Merck Patent GmbH 02/19/192D 3D TSV
US9580415 36 Compounds Proximagen Limited 02/19/192D 3D TSV
US9580412 102 Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated diseases GALDERMA RESEARCH & DEVELOPMENT 02/19/192D 3D TSV
US9580432 134 Fused pyrimidine compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. 02/19/192D 3D TSV
US9579320 492 Inhibitors of syk and JAK protein kinases Portola Pharmaceuticals, Inc. 02/19/192D 3D TSV
US9579407 4 Radiolabeled compounds and their use as radiotracers for quantitative imaging of phosphodiesterase (PDE10A) in mammals TAKEDA PHARMACEUTICAL COMPANY LIMITED 02/19/192D 3D TSV
US9580411 11 Substituted sulfonamide compounds Hoffmann-La Roche Inc. 02/19/192D 3D TSV
US9580442 52 Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors Karus Therapeutics Limited 02/19/192D 3D TSV
US10098883 105 (Aza)pyridopyrazolopyrimidinones and indazolopyrimidinones and their use BAYER PHARMA AKTIENGESELLSCHAFT 02/18/192D 3D TSV
US10100018 136 Amide derivatives as lysophosphatidic acid receptor antagonists Takeda Pharmaceutical Company Limited 02/18/192D 3D TSV
US10098902 131 Arginase inhibitors as therapeutics Mars, Incorporated 02/18/192D 3D TSV
US10100016 53 Condensed ring derivative, and preparation method, intermediate, pharmaceutical composition and use thereof SHANGHAI YINGLI PHARMACEUTICAL CO., LTD. 02/18/192D 3D TSV
US10099993 358 Metabotropic glutamate receptor positive allosteric modulators (PAMS) and uses thereof SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE 02/18/192D 3D TSV
US10098900 5 Pharmaceutical compositions and their use for treatment of cancer and autoimmune diseases ZHEJIANG DTRM BIOPHARMA CO. LTD. 02/18/192D 3D TSV
US10098888 22 Substituted benzene compounds Epizyme, Inc. 02/18/192D 3D TSV
US10093671 40 2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis B virus infection Hoffmann-La Roche Inc. 01/23/192D 3D TSV
US9573958 74 Benzimidazole derivatives as ITK inhibitors PRINCIPIA BIOPHARMA, INC. 01/23/192D 3D TSV
US9572792 5 Coumarin compounds as receptor modulators with therapeutic utility Allergan, Inc. 01/23/192D 3D TSV
US9572802 96 Diamide compounds having muscarinic receptor antagonist and β2 adrenergic receptor agonist activity Theravance Respiratory Company LLC 01/23/192D 3D TSV
US10093683 74 Factor XIa inhibitors Merck Sharp & Dohme Corp. 01/23/192D 3D TSV
US10093697 12 IBAT inhibitors for the treatment of liver diseases TBA 01/23/192D 3D TSV
US9573957 151 Inhibitors of leukotriene production Boehringer Ingelheim International GmbH 01/23/192D 3D TSV
US9573930 122 Inhibitors of lysine specific demethylase-1 Celgene Quanticel Research, Inc. 01/23/192D 3D TSV
US9573961 95 Inhibitors of the renal outer medullary potassium channel Merck Sharp & Dohme Corp. 01/23/192D 3D TSV
US9573943 86 Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use Genentech, Inc. 01/23/192D 3D TSV
US10092575 221 Substituted thiophene- and furan-fused azolopyrimidine-5-(6H)-one compounds Dart NeuroScience (Cayman) Ltd. 01/23/192D 3D TSV
US10093673 15 Tetracyclic pyridone compounds as antivirals Novartis AG 01/23/192D 3D TSV
US9572811 103 Treatment of dry eye PRINCIPIA BIOPHARMA INC. 01/23/192D 3D TSV
US10093646 286 1-pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine derivatives and compositions thereof for inhibiting the activity of SHP2 Novartis AG 01/22/192D 3D TSV
US10093664 74 Bicyclo[1.1.1]pentane inhibitors of dual leucine zipper (DLK) kinase for the treatment of disease Board of Regents, The University of Texas System 01/22/192D 3D TSV
US10093631 12 Bifunctional compounds and use for reducing uric acid levels Acquist LLC 01/22/192D 3D TSV
US10093658 29 Bifunctional compounds and use for reducing uric acid levels Acquist LLC 01/22/192D 3D TSV
US10093651 5 Ghrelin O-acyl transferase inhibitors Eli Lilly and Company 01/22/192D 3D TSV
US10093655 81 Heteroaromatic compounds and their use as dopamine D1 ligands Pfizer Inc. 01/22/192D 3D TSV
US10093635 56 MAGL inhibitors ABIDE THERAPEUTICS, INC. 01/22/192D 3D TSV
US10093663 110 Piperidinyl-indole derivatives complement factor B inhibitors and uses thereof Novartis AG 01/22/192D 3D TSV
US10093660 261 Sulfoximine substituted quinazolines for pharmaceutical compositions EVOTEC INTERNATONAL GMBH 01/22/192D 3D TSV
US10093650 24 Tetrazolone-substituted dihydropyridinone MGAT2 inhibitors Bristol-Myers Squibb Company 01/22/192D 3D TSV
US10092570 368 Heterocyclylamines as PI3K inhibitors Incyte Holdings Corporation; Incyte Corporation 01/18/192D 3D TSV
US10092529 7 Necrosis inhibitors National Institute of Biological Sciences, Beijing 01/18/192D 3D TSV
US10092563 408 Phosphatidylinositol 3-kinase inhibitors Gilead Sciences, Inc. 01/18/192D 3D TSV
US10092556 28 Piperidine compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. 01/18/192D 3D TSV
US10087191 87 Piperidine derivative and preparation method and pharmaceutical use thereof Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. 01/18/192D 3D TSV
US10092551 173 Spiro-thiazolones Hoffmann-LaRoche Inc. 01/18/192D 3D TSV
US10087144 18 Agents for use in the treatment of cardiovascular and inflammatory diseases structurally based on 4(1 H)-quinolone UCL Business PLC 01/17/192D 3D TSV
US10085988 5 Aglaroxin C and derivatives as HCV entry inhibitors SRI International; Trustees of Boston University 01/17/192D 3D TSV
US10085983 38 Azabicyclo derivatives, process for preparation thereof and medical use thereof Shanghai Haiyan Pharmaceutical Technology Co., Ltd.; Yangtze River Pharmaceutical Group Co., Ltd. 01/17/192D 3D TSV
US10087188 204 Benzamide imidazopyrazine Btk inhibitors Merck Sharp & Dohme Corp. 01/17/192D 3D TSV
US10087167 32 Benzofurans substituted with secondary benzamide as HCV inhibitors Bristol-Myers Squibb Company 01/17/192D 3D TSV
US10087181 30 Compound as WNT signaling inhibitor, composition, and use thereof CUREGENIX, INC. 01/17/192D 3D TSV
US10087185 125 Fused bicylic pyridine compounds and their use as AMPA receptor modulators Janssen Pharmaceutica NV 01/17/192D 3D TSV
US10087187 510 Imidazopyridazine derivatives as PI3KB inhibitors Janssen Pharmaceutica NV 01/17/192D 3D TSV
US10085984 272 Metalloenzyme inhibitor compounds Viamet Pharmaceuticals (Bermuda), Ltd. 01/17/192D 3D TSV
US10087143 160 Pyridone amides as modulators of sodium channels VERTEX PHARMACEUTICALS INCORPORATED 01/17/192D 3D TSV
US10085986 20 Pyrimidinone compounds and their use Takeda Pharmaceutical Company Limited 01/17/192D 3D TSV
US9567341 72 Pyrrolopyrimidine derivatives as NR2B NMDA receptor antagonists Rugen Holdings (Cayman) Limited 01/17/192D 3D TSV
US10087148 49 Quinazolines as biogenic amine transport modulators THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTE OF HEALTH; SOUTHERN RESEARCH INSTITUTE 01/17/192D 3D TSV
US9567334 150 Quinolone derivatives as fibroblast growth factor receptor inhibitors Principia Biopharma, Inc. 01/17/192D 3D TSV
US9567324 34 Substituted nicotinamide derivatives as kinase inhibitors ALLERGAN, INC. 01/17/192D 3D TSV
US10087178 163 Substituted spiropyrido[1,2-a]pyrazine derivative and medicinal use thereof as HIV integrase inhibitor JAPAN TOBACCO INC. 01/17/192D 3D TSV
US10086000 131 Tricyclic compounds as inhibitors of mutant IDH enzymes Merck Sharp & Dohme Corp. 01/17/192D 3D TSV
US10085990 88 Tricyclic compounds as modulators of TNF-α synthesis and as PDE4 inhibitors vTv Therapeutics LLC 01/17/192D 3D TSV
US9518026 206 5-aminopyrazole-4-carboxamide inhibitors of CDPK1 from T. gondii and C. parvum University of Washington Through its Center For Commercialization 01/14/192D 3D TSV
US9518000 100 Bicyclo [2.2.1] acid GPR120 modulators Bristol-Myers Squibb Company 01/14/192D 3D TSV
US9517228 8 Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes Jenrin Discovery, Inc. 01/14/192D 3D TSV
US9566312 321 Cyclic peptides and use as medicines Novartis AG 01/14/192D 3D TSV
US9567327 3 Imidazo[1,2-a]pyridine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto Arena Pharmaceuticals, Inc. 01/14/192D 3D TSV
US9518055 38 Imidazopyridyl compounds as aldosterone synthase inhibitors Merck Sharp & Dohme 01/14/192D 3D TSV
US9518064 131 Imidazothiadiazole and imidazopyridazine derivatives as protease activated receptor 4 (PAR4) inhibitors for treating platelet aggregation Bristol-Myers Squibb Company; Universite De Montreal 01/14/192D 3D TSV
US9566277 5 Methods of using phthalazinone ketone derivatives Jiangsu Hansoh Pharmaceutical Co., Ltd. 01/14/192D 3D TSV
US9567339 358 Primary carboxamides as BTK inhibitors AbbVie Inc. 01/14/192D 3D TSV
US9567338 61 Pyrazolo[3,4-d]pyrimidine compounds, their preparation and use as sigma ligands LABORATORIOS DEL DR. ESTEVE S.A. 01/14/192D 3D TSV
US9518052 676 Pyrazolopyridines and pyrazolopyrimidines Pfizer Inc. 01/14/192D 3D TSV
US9567320 29 Pyridazinone-amides derivatives MERCK PATENT GmbH 01/14/192D 3D TSV
US9567304 358 Quinazolinedione derivative Chugai Seiyaku Kabushiki Kaisha 01/14/192D 3D TSV
US9518060 98 Substituted pyrrolo[3,4-c]pyrazoles as PKC kinase inhibitors PFIZER INC. 01/14/192D 3D TSV
US9567333 14 Triazolopyridyl compounds as aldosterone synthase inhibitors Merck Sharp & Dohme Corp. 01/14/192D 3D TSV
US10081635 20 Substituted N-(pyrrolidine-3-yl)-7H-pyrrolo[2,3-D]pyrimidine-4-amine as janus kinase inhibitor YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD. 01/13/192D 3D TSV
US10081632 21 Substituted tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-α]pyrazine-2-carboxamides as RSK inhibitors PHOENIX MOLECULAR DESIGNS 01/13/192D 3D TSV
US10081629 107 Amide derivatives and pharmaceutically acceptable salts thereof, preparation method thereof and medicinal application thereof Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. 01/12/192D 3D TSV
US10081623 35 Diamide macrocycles that are FXIa inhibitors Bristol-Myers Squibb Company 01/12/192D 3D TSV
US10081617 134 Factor XIa inhibitors Merck Sharp & Dohme Corp. 01/12/192D 3D TSV
US10081606 46 Heteroaryl compounds and uses thereof Celgene CAR LLC 01/12/192D 3D TSV
US10081602 42 Opioid agonists and uses thereof Nektar Therapeutics 01/12/192D 3D TSV
US10081622 12 Substituted indazole derivatives active as kinase inhibitors NERVIANO MEDICAL SCIENCES S.R.L. 01/12/192D 3D TSV
US10080750 243 Aminopyrimidine derivatives for use as modulators of kinase activity Merck Patent GmbH 01/11/192D 3D TSV
US10077277 38 Bicyclic heteroarylaminoalkyl phenyl derivatives as PI3K inhibitors Incyte Corporation 01/11/192D 3D TSV
US10023583 56 Bicyclic pyridine compound Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. 01/11/192D 3D TSV
US10023592 505 Bromodomain inhibitors Celgene Quanticel Research, Inc. 01/11/192D 3D TSV
US10077289 76 Cyclosporins modified on the MeBmt sidechain by heterocyclic rings Allergan, Inc. 01/11/192D 3D TSV
US10081601 41 Glucocerebrosidase modulators and uses thereof Alectos Therapeutics Inc. 01/11/192D 3D TSV
US10077272 23 Heteroaromatic compounds and their use as dopamine D1 ligands Pfizer Inc. 01/11/192D 3D TSV
US10023576 117 Heteroaryl substituted pyrrolotriazine amine compounds as PI3K inhibitors Bristol-Myers Squibb Company 01/11/192D 3D TSV
US10077269 372 Imidazopyridazine compounds Pfizer Inc. 01/11/192D 3D TSV
US10077273 54 SHMT inhibitors The Trustees of Princeton University 01/11/192D 3D TSV
US10077265 28 Substituted oxopyridine derivatives BAYER PHARMA AKTIENGESELLSCHAFT 01/11/192D 3D TSV
US10077266 142 Substituted pyrido[3,4-b]pyrazines as GPR6 modulators TAKEDA PHARMACEUTICAL COMPANY LIMITED 01/11/192D 3D TSV
US10080744 176 Thiazoles as modulators of RORγt Janssen Pharmaceutica NV 01/11/192D 3D TSV
US10077247 54 Tricyclic spiro compound ONO PHARMACEUTICAL CO., LTD. 01/11/192D 3D TSV
US10023575 202 Cyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxyamide Boehringer Ingelheim International GmbH 01/10/192D 3D TSV
US10023564 139 G protein-coupled receptor kinase 2 inhibitors and methods for use of the same THE REGENTS OF THE UNIVERSITY OF MICHIGAN 01/10/192D 3D TSV
US10023562 168 Heteroaryl substituted pyridyl compounds useful as kinase modulators Bristol-Myers Squibb Company 01/10/192D 3D TSV
US10023570 1162 Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Array BioPharma Inc. 01/10/192D 3D TSV
US10023539 107 Aryl-cyanoguanidine compounds Bayer Pharma Aktiengesellschaft 01/06/192D 3D TSV
US10023561 74 Fumagillol heterocyclic compounds and methods of making and using same Zafgen, Inc. 01/06/192D 3D TSV
US10023543 122 Inhibitors of lysine specific demethylase-1 CELGENE QUANTICEL RESEARCH, INC. 01/06/192D 3D TSV
US10023559 262 Substituted azetidine derivatives Hoffman-La Roche Inc. 01/06/192D 3D TSV
US10023557 451 Therapeutic inhibitory compounds LIFESCI PHARMACEUTICALS, INC. 01/06/192D 3D TSV
US9884865 4 Azaspiro[4.5] decane derivatives and use thereof Purdue Pharma L.P. 01/05/192D 3D TSV
US9884874 18 Bromodomain-inhibiting compounds and pharmaceutical composition comprising same for preventing or treating a cancer KAINOS MEDICINE, INC. 01/05/192D 3D TSV
US9884843 140 Cyclic sulfone and sulfoximine analogs and uses thereof PELOTON THERAPEUTICS, INC. 01/05/192D 3D TSV
US9884878 845 FLAP modulators JANSSEN PHARMACEUTICA NV 01/05/192D 3D TSV
US9884860 365 Fused pyrroledicarboxamides and their use as pharmaceuticals Sanofi 01/05/192D 3D TSV
US9884850 16 Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors ACETYLON PHARMACEUTICALS, INC. 01/05/192D 3D TSV
US9884828 117 Substituted cinnolines as inhibitors of LRRK2 kinase activity Imago Pharmaceuticals, Inc. 01/05/192D 3D TSV
US9884868 605 TGF-beta inhibitors Rigel Pharmaceuticals, Inc.; Bristol-Myers Squibb Company 01/05/192D 3D TSV
US10022387 157 Aza-heteroaryl compounds as PI3K-gamma inhibitors Incyte Corporation 12/31/182D 3D TSV
US10023528 16 Branched 3-phenylpropionic acid derivatives and their use BAYER PHARMA AKTIENGESELLSCHAFT 12/31/182D 3D TSV
US10023534 22 Carbazole and tetrahydrocarbazole compounds useful as inhibitors of BTK Bristol-Myers Squibb Company 12/31/182D 3D TSV
US10023519 68 Cyclobutane containing carboxylic acid GPR120 modulators Bristol-Myers Squibb Company 12/31/182D 3D TSV
US10030026 52 Difluoroethylpyridine derivatives as NR2B NMDA receptor antagonists Rugen Holdings (Cayman) Limited 12/31/182D 3D TSV
US10030016 798 Heterocyclic compounds useful as PDK1 inhibitors Sunesis Pharmaceuticals, Inc.; Millenium Pharmaceuticals, Inc. 12/31/182D 3D TSV
US10022352 15 Modulators of ATP-binding cassette transporters Vertex Pharmaceuticals Incorporated 12/31/182D 3D TSV
US10030047 55 Peptide macrocycles against acinetobacter baumannii HOFFMANN-LA ROCHE INC. 12/31/182D 3D TSV
US10022376 676 Pyrazolopyridines and pyrazolopyrimidines Pfizer Inc. 12/31/182D 3D TSV
US10022354 246 Pyrrolidine amide compounds as histone demethylase inhibitors GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS INC. 12/31/182D 3D TSV
US10022461 105 Pyrrolo[2,3-C]pyridines as imaging agents for neurofibrilary tangles Merck Sharp & Dohme Corp. 12/31/182D 3D TSV
US10030027 248 Soluble guanylate cyclase stimulators Merck Sharp & Dohme Corp. 12/31/182D 3D TSV
US10030020 677 Spirocycle compounds and methods of making and using same ABIDE THERAPEUTICS, INC. 12/31/182D 3D TSV
US10030025 205 Substituted [1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists OGEDA SA 12/31/182D 3D TSV
US10030004 207 Compounds and methods of use Medivation Technologies LLC 12/30/182D 3D TSV
US10029993 68 Disubstituted 1, 2, 4-triazine compound MITSUBISHI TANABE PHARMA CORPORATION 12/30/182D 3D TSV
US10030012 100 Piperidin-1-yl and azepin-1-yl carboxylates as muscarinic M4 receptor agonists Heptares Therapeutics Limited 12/30/182D 3D TSV
US10028961 1070 Therapeutically active compounds and their methods of use Agios Pharmaceuticals, Inc. 12/30/182D 3D TSV
US10034864 21 1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase Incyte Holdings Corporation; Incyte Corporation 12/25/182D 3D TSV
US10034861 606 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors H. Lundbeck A/S 12/25/182D 3D TSV
US10035761 33 Compositions, synthesis, and methods of using phenylcycloalkylmethylamine derivatives Revivia Pharmaceuticals, Inc. 12/25/182D 3D TSV
US10035797 73 Fused amino pyridine as HSP90 inhibitors Curis, Inc. 12/25/182D 3D TSV
US10035814 18 Guanine analogs as telomerase substrates and telomere length affectors Geron Corporation 12/25/182D 3D TSV
US10035794 139 Heterocyclic derivatives and their use in the treatment of neurological disorders Novartis AG 12/25/182D 3D TSV
US10035777 109 Heterocyclic kinase inhibitors Bristol-Myers Squibb Company 12/25/182D 3D TSV
US10035760 349 Inhibitors of human immunodeficiency virus replication ViiV HEALTHCARE UK (NO. 5) LIMITED 12/25/182D 3D TSV
US10035778 119 Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists Saint Louis University 12/25/182D 3D TSV
US10028960 106 Pyrimidine compounds as JAK kinase inhibitors THERAVANCE BIOPHARMA R&D IP, LLC 12/25/182D 3D TSV
US10035780 9 Quinazoline scaffold based compounds, pharmaceutical compositions and methods of use thereof TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. 12/25/182D 3D TSV
US10035792 71 Resorcinol derivative as HSP90 inhibitor CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. 12/25/182D 3D TSV
US10035804 122 Spirodiamine derivatives as aldosterone synthase inhibitors Hoffman-La Roche Inc. 12/25/182D 3D TSV
US10028934 74 Substituted indazole derivatives active as kinase inhibitiors NERVIANO MEDICAL SCIENCES S.R.L. 12/25/182D 3D TSV
US10034939 22 Synergistic combination of immunologic inhibitors for the treatment of cancer The University of Chicago 12/25/182D 3D TSV
US10040788 63 1,3,4-thiadiazole compounds and their use in treating cancer AstraZeneca AB; Cancer Research Technology Limited 12/22/182D 3D TSV
US10040789 28 1,3,4-thiadiazole compounds and their use in treating cancer AstraZeneca AB; Cancer Research Technology Limited 12/22/182D 3D TSV
US10040815 21 3-substituted 5-amino-6H-thiazolo[4,5-d]pyrimidine-2,7-dione compounds for the treatment and prophylaxis of virus infection Hoffmann-La Roche Inc. 12/22/182D 3D TSV
US10040790 162 Bicyclic heterocycles as FGFR inhibitors Incyte Holdings Corporation; Incyte Corporation 12/22/182D 3D TSV
US10040791 334 Isoxazole derivative as mutant isocitrate dehydrogenase 1 inhibitor Daiichi Sankyo Company, Limited; National Cancer Center 12/22/182D 3D TSV
US10040798 117 Pyrrolopyridazine inhibitors of IRAK4 activity Merck Sharp & Dohme Corp. 12/22/182D 3D TSV
US10040805 19 Substituted imidazo[1,5-a]pyrazines as Btk inhibitors Merck Sharp & Dohme Corp. 12/22/182D 3D TSV
US10040802 109 Thienopyrazine inhibitors of IRAK4 activity Merck Sharp & Dohme Corp. 12/22/182D 3D TSV
US10071086 115 1H-pyrazolo[3,4-b]pyridines and therapeutic uses thereof Samumed, LLC 12/21/182D 3D TSV
US10072005 105 4-azaindole derivatives Eisai R&D Management Co., Ltd. 12/21/182D 3D TSV
US10072026 1144 Crystalline form of 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile THERAVANCE BIOPHARMA R&D IP, LLC 12/21/182D 3D TSV
US10071992 17 Diacylglycerol acyl transferase 2 inhibitors Pfizer Inc. 12/21/182D 3D TSV
US10072025 140 Ethyl N-boc piperidinyl pyrazolo pyridones as Janus kinase inhibitors Merck Sharp & Dohme Corp. 12/21/182D 3D TSV
US10071984 129 Histone demethylase inhibitors Celgene Quanticel Research, Inc. 12/21/182D 3D TSV
US10040779 237 Histone demethylase inhibitors Celgene Quanticel Research, Inc. 12/21/182D 3D TSV
US10071998 58 Iminothiadiazine dioxides bearing an amine-linked substituent as BACE inhibitors, compositions, and their use TBA 12/21/182D 3D TSV
US10072034 37 Kinase inhibitors Respivert Limited; Topivert Pharma Limited 12/21/182D 3D TSV
US10071974 169 Morpholine and 1,4-oxazepane amides as somatostatin receptor subtype 4 (SSTR4) agonists Boehringer Ingelheim International GmbH 12/21/182D 3D TSV
US10071957 138 N-substituted benzamides and methods of use thereof GENENTECH, INC.; XENON PHARMACEUTICALS INC. 12/21/182D 3D TSV
US10071994 3 N-sulfonyl homoserine lactone derivatives, preparation method and use thereof Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China 12/21/182D 3D TSV
US10071110 33 Phosphonate compounds The Regents of the University of California 12/21/182D 3D TSV
US10071965 42 Pyridone FabI inhibitors and uses thereof THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK 12/21/182D 3D TSV
US10072008 7 Spiro-isoquinoline-3,4′-piperidine compounds having activity against pain ESTEVE PHARMACEUTICALS S.A. 12/21/182D 3D TSV
US10071988 647 Substituted 1,2,3-triazoles as NR2B-selective NMDA modulators JANSSEN PHARMACEUTICA NV 12/21/182D 3D TSV
US10072016 247 Substituted 4-phenylpiperidines, their preparation and use THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 12/21/182D 3D TSV
US10071995 38 Substituted oxopyridine derivatives BAYER PHARMA AKTIENGESELLSCHAFT 12/21/182D 3D TSV
US10071991 18 Substituted pyridine derivatives useful as c-fms kinase inhibitors Janssen Pharmaceutica NV 12/21/182D 3D TSV
US10072001 527 Tank-binding kinase inhibitor compounds Gilead Sciences, Inc. 12/21/182D 3D TSV
US10040781 1854 Tank-binding kinase inhibitor compounds Gilead Sciences, Inc. 12/21/182D 3D TSV
US10072003 130 Tetrahydronaphthyridine derivatives as mGluR2-negative allosteric modulators, compositions, and their use TBA 12/21/182D 3D TSV
US9878996 42 2-imidazolyl-pyrimidine scaffolds as potent and selective inhibitors of neuronal nitric oxide synthase Northwestern University 12/12/182D 3D TSV
US9884814 277 Acylguanidines for treating osteoarthritis MERCK PATENT GMBH 12/12/182D 3D TSV
US10065972 193 Bicyclic or tricyclic heterocyclic compound MITSUBISHI TANABE PHARMA CORPORATION 12/12/182D 3D TSV
US9884048 326 ERK inhibitors MERCK SHARP & DOHME CORP. 12/12/182D 3D TSV
US9556117 95 Indole carboxamide derivatives as P2X7 receptor antagonists ACTELION PHARMACEUTICALS LTD. 12/12/182D 3D TSV
US9556190 94 Piperidinyloxy lactone orexin receptor antagonists MERCK SHARP & DOHME CORP. 12/12/182D 3D TSV
US9879013 12 Purinone derivative ONO PHARMACEUTICAL CO., LTD. 12/12/182D 3D TSV
US9879032 46 Pyridine compounds Daiichi Sankyo Company, Limited; Sandford Burnham Prebys Medical Discovery Institute 12/12/182D 3D TSV
US9550796 455 Pyrrolopyrrolone derivatives and their use as BET inhibitors NOVARTIS AG 12/12/182D 3D TSV
US9951047 4 Salt of monocyclic pyridine derivative and crystal thereof Eisai R&D Management Co., Ltd. 12/12/182D 3D TSV
US9556188 218 Substituted imidazo[1,2-b]pyrazoles as bruton'S tyrosine kinase modulators BeiGene, Ltd. 12/12/182D 3D TSV
US9556179 949 Substituted imidazoles as casein kinase 1 D/E inhibitors Bristol-Myers Squibb Company 12/12/182D 3D TSV
US9556187 1933 Substituted pyrrolo[3′,2′:5,6]pyrido[4,3-d]pyrimidines and JAK inhibitors comprising the same NISSAN CHEMICAL INDUSTRIES, LTD. 12/12/182D 3D TSV
US9879026 27 Substituted spirocycles Boehringer Ingelheim International GmbH 12/12/182D 3D TSV
US9878991 226 TRPV1 antagonists including dihydroxy substituent and uses thereof Purdue Pharma L.P. 12/12/182D 3D TSV
US9877957 81 Tetrahydroisoquinoline derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2 Merck Sharp & Dohme Corp. 12/12/182D 3D TSV
US10059669 24 2-amino-3,5-difluoro-3,6-dimethyl-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors for treating alzheimer's disease H. Lundbeck A/S 12/11/182D 3D TSV
US10058540 19 2-amino-5,5-difluoro-6-(fluoromethyl)-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors H. Lundbeck A/S 12/11/182D 3D TSV
US10059713 296 3-substituted 2-amino-indole derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED 12/11/182D 3D TSV
US10059705 452 Acyclic cyanoethylpyrazolo pyridones as janus kinase inhibitors Merck Sharp & Dohme Corp. 12/11/182D 3D TSV
US10065941 574 Aminotriazine derivative and pharmaceutical composition comprising the same SHIONOGI & CO., LTD. 12/11/182D 3D TSV
US10059667 216 Antidiabetic compounds Merck Sharp & Dohme Corp. 12/11/182D 3D TSV
US10058534 230 Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders Novartis AG 12/11/182D 3D TSV
US10065961 90 Chiral N-acyl-5,6,7,(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor mediated disorders and chiral synthesis thereof Ogeda SA. 12/11/182D 3D TSV
US10059709 84 Compounds Elanco Tiergesundheit AG 12/11/182D 3D TSV
US10064873 147 Compounds and compositions for treating HIV with derivatives of Betulin GLAXOSMITHKLINE LLC 12/11/182D 3D TSV
US10064853 26 Compounds for use in methods for treating diseases or conditions mediated by protein disulfide isomerase Beth Israel Deaconess Medical Center, Inc.; The Broad Institute, Inc. 12/11/182D 3D TSV
US10065967 43 Compounds that are ERK inhibitors Merck, Sharp & Dohme Corp. 12/11/182D 3D TSV
US10059695 67 Cot modulators and methods of use thereof GILEAD SCIENCES, INC. 12/11/182D 3D TSV
US10065963 620 Heterocyclic compounds as PI3K-γ inhibitors Incyte Corporation 12/11/182D 3D TSV
US10065948 96 Histone deacetylase inhibitors and compositions and methods of use thereof CHDI Foundation, Inc. 12/11/182D 3D TSV
US10059687 128 Histone demethylase inhibitors Celgene Quanticel Research, Inc. 12/11/182D 3D TSV
US10058549 3 Imidazo[1,2-α]pyridine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto Arena Pharmaceuticals, Inc. 12/11/182D 3D TSV
US10065953 19 Imidazo[1,2-A]pyridine derivatives for use as inhibitors of human immunodeficiency virus replication ViiV HEALTHCARE UK (NO.5) LIMITED 12/11/182D 3D TSV
US10065945 9 Isoquinoline derivatives as MGAT2 inhibitors Merck Sharp & Dohme Corp. 12/11/182D 3D TSV
US10059668 41 LSD1 inhibitors Mirati Therapeutics, Inc. 12/11/182D 3D TSV
US10064861 81 Macrocyclic pyridazinone derivatives Merck Patent GmbH 12/11/182D 3D TSV
US10058550 788 Methods of treating heart failure AMGEN INC. 12/11/182D 3D TSV
US10059688 43 Protein tyrosine kinase modulators and methods of use BETTA PHARMACEUTICALS CO., LTD. 12/11/182D 3D TSV
US10059720 288 Pyridine derivative Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. 12/11/182D 3D TSV
US10065928 42 Quinolinone compound and use thereof SUNSHINE LAKE PHARMA CO., LTD. 12/11/182D 3D TSV
US10065973 23 Substituted aminothiazolopyrimidinedione for the treatment and prophylaxis of virus infection Hoffmann-La Roche Inc. 12/11/182D 3D TSV
US10065950 358 Substituted thiazoles as HIV integrase inhibitors Japan Tobacco Inc. 12/11/182D 3D TSV
US10065970 215 Tricyclic PI3K inhibitor compounds and methods of use Genentech, Inc. 12/11/182D 3D TSV
US10071079 2922 [1,2,4]triazolo[1,5-a]pyridinyl substituted indole compounds Bristol-Myers Squibb Company 12/11/182D 3D TSV
US9718813 168 Imidazolin-5-one derivative useful as FASN inhibitors for the treatment of cancer Janssen Pharmaceutica NV 12/10/182D 3D TSV
US9718825 648 N-(4-(azaindazol-6-yl)-phenyl)-sulfonamides and their use as pharmaceuticals SANOFI 12/10/182D 3D TSV
US9549932 488 2-(morpholin-4-yl)-1,7-naphthyridines Bayer Pharma Aktiengesellschaft 11/29/182D 3D TSV
US9718828 489 BTK Inhibitors MERCK SHARP & DOHME CORP.; MERCK SHARP & DOHME B.V. 11/29/182D 3D TSV
US9550771 93 Keto-imidazopyridine derivatives as RORc modulators Genentech, Inc. 11/29/182D 3D TSV
US9718822 68 Macrocyclic compounds as Trk kinase inhibitors Array BioPharma, Inc. 11/29/182D 3D TSV
US9718854 20 Selective glycosidase inhibitors and uses thereof Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. 11/29/182D 3D TSV
US9718820 90 Substituted aza-bicyclic imidazole derivatives useful TRPM8 receptor modulators JANSSEN PHARMACEUTICA NV 11/29/182D 3D TSV
US9550775 130 Substituted triazolopyridines and methods of use thereof GENENTECH, INC.; XENON PHARMACEUTICALS INC. 11/29/182D 3D TSV
US9718814 375 Cyclopropanamine compound and use thereof Takeda Pharmaceutical Company Limited 11/28/182D 3D TSV
US9718819 182 Non-nucleoside reverse transcriptase inhibitors Merck Sharp & Dohme Corp. 11/28/182D 3D TSV
US9718812 213 Substituted thiazole or oxazole P2X7 receptor antagonists Axxam S.P.A. 11/28/182D 3D TSV
US9718809 87 Bisarylsulfonamides useful in the treatment of inflammation and cancer Kancera AB 11/27/182D 3D TSV
US9718800 115 Chromenone derivatives ASTRAZENECA AB 11/27/182D 3D TSV
US9718808 144 Inhibitors of the renal outer medullary potassium channel Merck Sharp & Dohme Corp. 11/27/182D 3D TSV
US9718793 138 Isoxazole compounds as inhibitors of heat shock proteins Vernalis (R&D) Ltd.; Cancer Research Technology Limited; The Institute of Cancer Research 11/27/182D 3D TSV
US9718792 101 Isoxazoline hydroxamic acid derivatives as LpxC inhibitors Novartis AG 11/27/182D 3D TSV
US9718790 2250 Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same SHIONOGI & CO., LTD. 11/27/182D 3D TSV
US9718803 375 Unsaturated nitrogen heterocyclic compounds useful as PDE10 inhibitors Amgen Inc. 11/27/182D 3D TSV
US9718771 48 Aniline derivative, pharmaceutical composition containing same, and use thereof KISSEI PHARMACEUTICAL CO., LTD. 11/16/182D 3D TSV
US9718787 9 Poly (ADP-ribose) polymerase inhibitor CHENGDU DIAO PHARMACEUTICAL GROUP CO., LTD. 11/16/182D 3D TSV
US9718780 6 Substituted pyridines as sodium channel blockers TBA 11/16/182D 3D TSV
US9714242 13 Azabicyclic carbamates and their use as alpha-7 nicotinic acetylcholine receptor agonists Bayer Intellectual Property GmbH 11/15/182D 3D TSV
US9714234 70 Carbazole carboxamide compounds Bristol-Myers Squibb Company 11/15/182D 3D TSV
US9713651 56 Compositions, methods, and systems for the synthesis and use of imaging agents Lantheus Medical Imaging, Inc. 11/15/182D 3D TSV
US9714236 207 Compounds and methods for inhibiting JAK ASTRAZENECA AB 11/15/182D 3D TSV
US9713612 30 Compounds for treatment of cancer CUREGENIX, INC. 11/15/182D 3D TSV
US9714252 7 Cyclic sulfonamides as sodium channel blockers Purdue Pharma L.P. 11/15/182D 3D TSV
US9714241 375 Cyclopropanamine compound and use thereof Takeda Pharmaceutical Company Limited 11/15/182D 3D TSV
US9714266 46 Estra-1,3,5(10),16-tetraene-3-carboxamides for inhibition of 17.beta.-hydroxysteroid dehydrogenase (AKR1C3) BAYER PHARMA AKTIENGESELLSCHAFT 11/15/182D 3D TSV
US9714224 8 Heterocyclic compounds and methods of their use NOVARTIS AG 11/15/182D 3D TSV
US9714230 511 Histone demethylase inhibitors Celgene Quantical Research, Inc. 11/15/182D 3D TSV
US9713606 584 Methods for treating pulmonary emphysema using substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin C Boehringer Ingelheim International GmbH 11/15/182D 3D TSV
US9714247 452 Multiple kinase pathway inhibitors Tolero Pharmaceuticals, Inc.; Mannkind Corporation 11/15/182D 3D TSV
US9717745 5 Pharmaceutical compositions and their use for treatment of cancer and autoimmune diseases ZHEJIANG DTRM BIOPHARMA CO. LTD. 11/15/182D 3D TSV
US9718760 257 Plasminogen activator inhibitor-1 inhibitors and methods of use thereof THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY 11/15/182D 3D TSV
US9714249 134 Pyrazolo-pyrrolidin-4-one derivatives and their use in the treatment of disease Novartis AG 11/15/182D 3D TSV
US9714235 40 Quinazoline derivatives, compositions thereof, and use as pharmaceuticals Shanghai Fochon Pharmaceutical Co., Ltd. 11/15/182D 3D TSV
US9717714 14 Spirocyclic CETP inhibitors Merck Sharp & Dohme Corp. 11/15/182D 3D TSV
US9714221 654 Substituted 6,7-dihydro-5H-benzo[7]annulene compounds, processes for their preparation and therapeutic uses thereof SANOFI 11/15/182D 3D TSV
US9714232 72 Substituted piperazine compounds and methods of use thereof SUNSHINE LAKE PHARMA CO., LTD. 11/15/182D 3D TSV
US9714244 46 Substituted pyrido[4,3-d]pyrimidines as Wee-1 inhibitors ALMAC DISCOVERY LIMITED 11/15/182D 3D TSV
US9556130 73 4-oxo-3,4-dihydro-1,2,3-benzotriazine modulators of GPR139 Takeda Pharmaceutical Company Limited 11/08/182D 3D TSV
US9550741 612 Benzoisothiazole compounds and methods of treating schizophrenia Shanghai Institute of Pharmaceutical Industry 11/08/182D 3D TSV
US9556150 59 Inhibitors of bruton's tyrosine kinase Hoffmann-La Roche Inc.; Chugai Pharmaceutical Co. 11/08/182D 3D TSV
US9708370 88 Azapeptides as CD36 binding compounds VALORISATION-RECHERCHE, LIMITED PARTNERSHIP; VALORISATION HSJ, LIMITED PARTNERSHIP 11/07/182D 3D TSV
US9546162 91 Compounds and methods for skin repair ALLERGAN, INC. 11/07/182D 3D TSV
US9533987 230 Heterocyclic derivates Kalvista Pharmaceuticals Limited 11/07/182D 3D TSV
US9546164 648 Substituted benzamides and methods of use thereof GENENTECH, INC.; XENON PHARMACEUTICALS INC. 11/07/182D 3D TSV
US9708337 36 Aryl amide-based kinase inhibitors Bristol-Myers Squibb Company 11/05/182D 3D TSV
US9708336 2511 Metallo-beta-lactamase inhibitors Merck Sharp & Dohme Corp. 11/05/182D 3D TSV
US9708359 143 Pyrrolopyrimidine nucleosides and analogs thereof Chimerix, Inc.; The Regents of the University of Michigan 11/05/182D 3D TSV
US9708340 96 Urea derivatives and their use as fatty-acid binding protein (FABP) inhibitors Hoffmann-La Roche Inc. 11/05/182D 3D TSV
US9708333 86 Fused bicyclic 1,2,4-triazine compounds as TAM inhibitors Incyte Corporation 11/01/182D 3D TSV
US9708309 24 Arylcyclopropylamine based demethylase inhibitors of LSD1 and their medical use ORYZON GENOMICS, S.A. 10/31/182D 3D TSV
US9708311 143 Benzimidazole derivatives as EP4 antagonists BAYER PHARMA AKTIENGESELLSCHAFT 10/31/182D 3D TSV
US9708318 856 Bicyclic heterocycles as FGFR4 inhibitors Incyte Corporation 10/31/182D 3D TSV
US9708302 46 Flouro-naphthyl derivatives HOFFMANN-LA-ROCHE INC. 10/31/182D 3D TSV
US9708313 142 Substituted pyrido[3,4-b]pyrazines as GPR6 modulators Takeda Pharmaceutical Company Limited 10/31/182D 3D TSV
US9708325 62 Sulfonimidoylpurinone compounds and derivatives for the treatment and prophylaxis of virus infection Hoffmann-La Roche Inc. 10/31/182D 3D TSV
US9708279 100 2-acylaminothiazoles for the treatment of cancer UNIVERSITÁ DEGLI STUDI DI MILANO—BICOCCA; UNIVERSITÈ DE GENÈVE; UNIVERSITÈ CLAUDE BERNARD LYON 1 10/30/182D 3D TSV
US10053471 17 Azabenzimidazole derivatives Boehringer Ingelheim International GmbH 10/30/182D 3D TSV
US9708266 40 Cyclohexyl pyridine derivative KISSEI PHARMACEUTICAL CO., LTD. 10/30/182D 3D TSV
US9708253 135 Cyclohexyl sulfone RORγ modulators Bristol-Myers Squibb Company 10/30/182D 3D TSV
US9701672 77 Dihydropyridinone MGAT2 inhibitors for use in the treatment of metabolic disorders Bristol-Myers Squibb Company 10/30/182D 3D TSV
US9708275 12 Heterocyclic compounds and methods for their use NOVARTIS AG 10/30/182D 3D TSV
US9707233 368 Heterocyclylamines as PI3K inhibitors Incyte Holdings Corporation; Incyte Corporation 10/30/182D 3D TSV
US9708272 22 Inhibitors of α-amino-β-carboxymuconic acid semialdehyde decarboxylase TES Pharma S.r.l. 10/30/182D 3D TSV
US9700563 3 Kappa opioid receptor compounds MediSynergies, LLC 10/30/182D 3D TSV
US10053462 195 P2X7 modulators Janssen Pharmaceutica NV 10/30/182D 3D TSV
US9701669 34 Preparation and use of 7a-amide substituted- 6,6-difluoro bicyclic himbacine derivatives as PAR-1 receptor antagonists Merck Sharp & Dohme Corp. 10/30/182D 3D TSV
US9708269 7 Process for making isoquinoline compounds FibroGen, Inc. 10/30/182D 3D TSV
US9701670 374 Pyrazolyl-ureas as kinase inhibitors RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED 10/30/182D 3D TSV
US10053465 286 Pyrrolopyrimidine derivatives as TAM inhibitors Incyte Corporation 10/30/182D 3D TSV
US9708268 42 ROR modulators and their uses INNOV17 LLC 10/30/182D 3D TSV
US9707205 16 S1P receptors modulators and their use thereof AKAAL PHARMA PTY LTD. 10/30/182D 3D TSV
US9701693 4 Selective glycosidase inhibitors and uses thereof Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. 10/30/182D 3D TSV
US9701685 18 Spiropyrrolidines as MDM2 inhibitors Hudson Biopharma Inc. 10/30/182D 3D TSV
US9708295 51 Substituted 2-aminopyridine protein kinase inhibitor CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD. 10/30/182D 3D TSV
US10053463 422 Substituted [1,2,4]triazolo[4,3-a]pyrazines as P2X7 modulators Janssen Pharmaceutica NV 10/30/182D 3D TSV
US9708270 91 Substituted spiropiperidinyl compounds useful as GPR120 agonists Merck Sharp & Dohme Corp. 10/30/182D 3D TSV
US9701663 37 Sulfonamide retinoic acid receptor-related orphan receptor modulators and uses thereof INNOV17 LLC 10/30/182D 3D TSV
US9708274 328 Sulfoximine substituted quinazolines for pharmaceutical compositions EVOTEC INTERNATIONAL GMBH 10/30/182D 3D TSV
US10053461 41 Tetracyclic 4-oxo-pyridine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis B virus infection Hoffmann-La Roche Inc. 10/30/182D 3D TSV
US9701638 16 Therapeutic hydroxyquinolones Rutgers, The State University of New Jersey 10/30/182D 3D TSV
US9701691 25 Thienopyrimidine compounds Hoffman-La Roche Inc. 10/30/182D 3D TSV
US9550763 437 Heterocyclic ring and carbocyclic derivative SHIONOGI & CO., LTD. 10/19/182D 3D TSV
US9546173 190 Substituted pyrrolo[3,4-d]pyrimidines as kinase inhibitors Novartis AG 10/19/182D 3D TSV
US10053433 20 Androgen receptor antagonists The Regents of the University of California 10/18/182D 3D TSV
US10053454 88 Carbazole compounds useful as bromodomain inhibitors Bristol-Myers Squibb Company 10/18/182D 3D TSV
US10053456 375 Cyclopropanamine compound and use thereof Takeda Pharmaceutical Company Limited 10/18/182D 3D TSV
US10053455 22 Diazaspiroalkaneone-substituted oxazole derivatives as spleen tyrosine kinase inhibitors AB SCIENCE 10/18/182D 3D TSV
US10053434 24 Histone deacetylase inhibitors and compositions and methods of use thereof CHDI FOUNDATION, INC. 10/18/182D 3D TSV
US10053458 216 Pyrimidine-2,4-diamine derivative and anticancer pharmaceutical composition comprising same as effective ingredient KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 10/18/182D 3D TSV
US10053431 514 Tetrahydro-benzodiazepinones Hoffmann-La Roche Inc. 10/18/182D 3D TSV
US9556139 260 6-substituted phenoxychroman carboxylic acid derivatives Array BioPharma Inc. 10/17/182D 3D TSV
US9556135 339 Amino-dihydrothiazine and amino-dioxido dihydrothiazine compounds as beta-secretase antagonists and methods of use Amgen, Inc. 10/17/182D 3D TSV
US10047118 7 C17-aryl substituted betulinic acid analogs ViiV HEALTHCARE UK (NO.5) LIMITED 10/17/182D 3D TSV
US10047086 158 Imidazopyridines and imidazopyrazines as LSD1 inhibitors Incyte Corporation 10/17/182D 3D TSV
US9556143 18 Metalloenzyme inhibitor compounds Viamet Pharmaceuticals, Inc. 10/17/182D 3D TSV
US9556168 60 N-alkylated indole and indazole compounds as RORgammaT inhibitors and uses thereof Merck Sharp & Dohme Corp. 10/17/182D 3D TSV
US9556148 86 N-cyanomethylamides as inhibitors of janus kinase Cadila Healthcare Limited 10/17/182D 3D TSV
US10052306 333 Selective octahydro-cyclopenta[C] pyrrole negative modulators of NR2B CADENT THERAPEUTICS, INC. 10/17/182D 3D TSV
US9555024 35 Substituted (E)-N′-(1-phenylethylidene)benzohydrazide analogs as histone demethylase inhibitors University of Utah Research Foundation 10/17/182D 3D TSV
US9555022 102 Substituted triazolopyridines Bayer Intellectual Property GmbH 10/17/182D 3D TSV
US10047080 42 (R)-2-methyl-piperazine derivatives as CXCR3 receptor modulators IDORSIA PHARMACEUTICALS LTD. 10/10/182D 3D TSV
US10045974 14 2-amino-6-(difluoromethyl)-5,5-difluoro-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors H. Lundbeck A/S 10/10/182D 3D TSV
US9556175 46 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and thier use as pharmaceutical compositions Boehringer Ingelheim International GmbH 10/10/182D 3D TSV
US10047073 12 Histone deacetylase inhibitors and compositions and methods of use thereof CHDI FOUNDATION, INC 10/10/182D 3D TSV
US10047084 43 Imidazolone derivatives, pharmaceutical compositions and uses thereof BEIJING FORELANDPHARMA CO. LTD. 10/10/182D 3D TSV
US10047093 120 Substituted imidazo[1,2-B]pyridazines as protein kinase inhibitors TOLERO PHARMACEUTICALS, INC. 10/10/182D 3D TSV
US9556191 8 Aminoquinazoline derivatives and their salts and methods of use thereof SUNSHINE LAKE PHARMA CO., LTD. 10/05/182D 3D TSV
US9556160 76 Guanidine compound Astellas Pharma Inc. 10/03/182D 3D TSV
US9562012 23 PPAR-sparing compounds for the treatment of metabolic diseases Metabolic Solutions Development Company, LLC 10/03/182D 3D TSV
US9561238 6 Pharmaceutical compositions comprising estetrol derivatives for use in cancer therapy Donesta Bioscience B.V. 10/03/182D 3D TSV
US10047098 188 C5-C6-oxacyclic fused iminopyrimidinone compounds as bace inhibitors, compositions, and their use Merck Sharp & Dohme Corp. 10/02/182D 3D TSV
US10047103 384 Imidazothiadiazole and imidazopyrazine derivatives as protease activated receptor 4 (PAR4) inhibitors for treating platelet aggregation Bristol-Myers Squibb Company; Universite de Montreal 10/02/182D 3D TSV
US10047097 105 Method of treatment using substituted pyrazolo[1,5-a] pyrimidine compounds Array BioPharma Inc. 10/02/182D 3D TSV
US10047092 276 Substituted [1,2,4]triazolo[4,3-a]pyrazines as P2X7 modulators Janssen Pharmaceutica NV 10/02/182D 3D TSV
US10047096 454 Substituted pyridobenzodiazepinone-derivatives and use thereof Bayer Pharma Aktiengesellschaft 10/02/182D 3D TSV
US9556181 21 Substituted pyrazolopyrimidinylamino-indazoles BAYER PHARMA AKTIENGESELLSCHAFT 09/30/182D 3D TSV
US9540377 1285 2,6,7,8 substituted purines as HDM2 inhibitors Merck Sharp & Dohme Corp. 09/26/182D 3D TSV
US9556157 6 Enhancer of zeste homolog 2 inhibitors GlaxoSmithKline Intellectual Property (No.2) Limited 09/26/182D 3D TSV
US9556170 3 Substituted-1H-benzo[d]imidazole series compounds as lysine-specific demethylase 1 (LSD1) inhibitors University of Utah Research Foundation 09/26/182D 3D TSV
US9546152 448 2-pyridyloxy-3-substituted-4-nitrile orexin receptor antagonists MERCK SHARP & DOHME CORP. 09/18/182D 3D TSV
US9546153 514 Bicyclic heterocycle substituted pyridyl compounds useful as kinase modulators Bristol-Myers Squibb Company 09/18/182D 3D TSV
US9533992 75 PDE9 inhibitors with imidazo triazinone backbone TBA 09/18/182D 3D TSV
US9550778 52 Substituted 6-aryl-imidazopyridine and 6-aryl-triazolopyridine carboxamide analogs as negative allosteric modulators of mGluR5 Vanderbilt University 09/18/182D 3D TSV
US9556111 23 Tertiary amines for use in the treatment of cardiac disorders UNIVERSITETET I OSLO 09/18/182D 3D TSV
US9556145 22 2-pyridyloxy-4-ester orexin receptor antagonists MERCK SHARP & DOHME CORP. 09/07/182D 3D TSV
US9540359 15 Dihydrooxazine or oxazepine derivatives having BACE1 inhibitory activity Shionogi & Co., Ltd. 09/07/182D 3D TSV
US9556147 7 Inhibitors of bruton's tyrosine kinase HOFFMANN-LA INC. 09/07/182D 3D TSV
US9550781 26 Kinase modulating compounds, compositions containing the same and use thereof Centaurus Biopharma Co., Ltd.; Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 09/07/182D 3D TSV
US9556132 41 Tetrazole derivatives and their use as potassium channel modulators Saniona A/S 09/07/182D 3D TSV
US9540396 38 6-arylamino pyridone carboxamide as MEK inhibitors Centaurus Biopharma Co., Ltd.; Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 08/28/182D 3D TSV
US9550755 5 Complement pathway modulators and uses thereof NOVARTIS AG 08/28/182D 3D TSV
US9546168 29 ERK inhibitors Merck Sharp & Dohme Corp. 08/28/182D 3D TSV
US9550774 2 Dihydropyrido pyrimidine compounds as autotaxin inhibitors Eli Lilly and Company 08/25/182D 3D TSV
US9527857 211 HSPC-sparing treatments for RB-positive abnormal cellular proliferation GI Therapeutics, Inc. 08/25/182D 3D TSV
US9540379 222 (1,2,4)triazolo[4,3-A]quinoxaline derivatives as inhibitors of phosphodiesterases Boehringer Ingelheim International GmbH 08/24/182D 3D TSV
US9539260 567 Dihydro-benzo-oxazine and dihydro-pyrido-oxazine derivatives NOVARTIS AG 08/24/182D 3D TSV
US9540357 74 15-aryl prostaglandins as EP4 agonists, and methods of use thereof Allergan, Inc. 08/16/182D 3D TSV
US9540323 274 7-hydroxy-indolinyl antagonists of P2Y1 receptor Bristol-Myers Squibb Company 08/16/182D 3D TSV
US9540388 197 P2X7 modulators Janssen Pharmaceutica NV 08/16/182D 3D TSV
US9527851 130 Pyrrole six-membered heteroaryl ring derivative, preparation method thereof, and medicinal uses thereof Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. 08/16/182D 3D TSV
US9540352 14 Substituted 1,7-naphthyridines as dopamine D1 ligands Pfizer Inc. 08/16/182D 3D TSV
US9670229 31 5-HT3 receptor antagonists Takeda Pharmaceutical Company Limited 08/07/182D 3D TSV
US9522914 174 Azole derivative TAISHO PHARMACEUTICAL CO., LTD 08/07/182D 3D TSV
US9540364 19 Benzimidazole tetrahydrofuran derivatives Merck Sharp & Dohme Corp. 08/07/182D 3D TSV
US9676777 3 Compounds useful for producing an optically active diazabicyclooctane compound MEIJI SEIKA PHARMA CO., LTD. 08/07/182D 3D TSV
US9533999 64 Fused thiazin-3-ones as KCA3.1 inhibitors Boehringer Ingelheim International GmbH 08/07/182D 3D TSV
US9670231 368 Fused tricyclic amide compounds as multiple kinase inhibitors BeiGene, Ltd. 08/07/182D 3D TSV
US9670230 12 Heteroaryl compounds and methods of use thereof Sunovion Pharmaceuticals Inc. 08/07/182D 3D TSV
US9676783 105 Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds Array BioPharma, Inc. 08/07/182D 3D TSV
US9670255 3 Modified biotin, mutant streptavidin, and use thereof SAVID THERAPEUTICS INC. 08/07/182D 3D TSV
US9676786 4 Pharmacologically active compounds THE UNIVERSITY OF LIVERPOOL 08/07/182D 3D TSV
US9676792 4 Pyrimido-diazepinone compounds and methods of treating disorders Dana-Farber Cancer Institute, Inc. 08/07/182D 3D TSV
US9540384 58 Pyrrolidino heterocycles Hoffmann-La Roche, Inc. 08/07/182D 3D TSV
US9533995 14 Substituted N-heteroaryl spirolactam bipyrrolidines, preparation and therapeutic use thereof Sanofi 08/07/182D 3D TSV
US9676782 342 Substituted pyrazolo[1,5-a]pyrazines as negative allosteric modulators of metabotropic glutamate receptor 3 Vanderbilt University 08/07/182D 3D TSV
US9540373 27 Substituted spirocycles Boehringer Ingelheim International GmbH 08/07/182D 3D TSV
US9676818 32 Toll-like receptor 2-agonistic lipopeptides, and method of making the same University of Kansas 08/07/182D 3D TSV
US9670211 45 Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection HOFFMANN-LA ROCHE INC. 07/07/182D 3D TSV
US9670216 58 Cannabinoid-2 agonists ALLERGAN, INC. 07/07/182D 3D TSV
US9670204 211 Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders GALAPAGOS NV 07/07/182D 3D TSV
US9670210 116 Cyclopropylamines as LSD1 inhibitors Incyte Corporation 07/07/182D 3D TSV
US9670220 66 Fused heterocyclic derivatives as S1P modulators Abbvie B.V.; AbbiVie Inc. 07/07/182D 3D TSV
US9670203 142 Fused tricyclic urea compounds as Raf kinase and/or Raf kinase dimer inhibitors BeiGene, Ltd. 07/07/182D 3D TSV
US9670212 191 Inhibitors of PI3K-delta and methods of their use and manufacture Exelixis, Inc. 07/07/182D 3D TSV
US9670209 69 Muscarinic agonists ACADIA PHARMACEUTICALS INC.; ALLERGAN, INC. 07/07/182D 3D TSV
US9670213 175 Pteridine ketone derivative and applications thereof as EGFR, BLK, and FLT3 inhibitor East China University of Science and Technology 07/07/182D 3D TSV
US9670208 48 Serine/threonine kinase inhibitors Array BioPharma Inc.; Genentech, Inc. 07/07/182D 3D TSV
US9670214 404 Small molecule myristate inhibitors of Bcr-abl and methods of use DANA-FARBER CANCER INSTITUTE, INC.; THE SCRIPPS RESEARCH INSTITUTE 07/07/182D 3D TSV
US9670136 210 (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors ORYZON GENOMICS S.A. 05/19/182D 3D TSV
US9670142 171 1,3-diaminocyclopentane carboxamide derivatives Merck Patent GmbH 05/19/182D 3D TSV
US9669034 227 4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group BAYER INTELLECTUAL PROPERTY GMBH 05/19/182D 3D TSV
US9670161 20 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfone group BAYER PHARMA AKTIENGESELLSCHAFT 05/19/182D 3D TSV
US9670157 271 Benzylamine derivatives Kalvista Pharmaceuticals Limited 05/19/182D 3D TSV
US9669035 66 Combinations comprising PDE 2 inhibitors such as 1-aryl-4-methyl-[1,2,4]triazolo-[4,3-A]]quinoxaline compounds and PDE 10 inhibitors for use in the treatment of neurological of metabolic disorders JANSSEN PHARMACEUTICA NV 05/19/182D 3D TSV
US9669095 13 Cyclosporin analogues for preventing or treating hepatitis C infection ENANTA PHARMACEUTICALS, INC. 05/19/182D 3D TSV
US9670195 3 Glycosidase inhibitors and uses thereof Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. 05/19/182D 3D TSV
US9669029 114 Heteroaromatic phenylimidazole derivatives as PDE10A enzyme inhibitors H. Lundbeck A/S 05/19/182D 3D TSV
US9669031 313 MNK inhibitors and methods related thereto eFFECTOR THERAPEUTICS, INC. 05/19/182D 3D TSV
US9670201 104 Methyl- and trifluoromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof Pfizer Inc. 05/19/182D 3D TSV
US9670191 116 Pyridyl-and pyrimidinyl-substituted pyrrole-, thiophene- and furane-derivatives as kinase inhibitors NERVIANO MEDICAL SCIENCES S.R.L. 05/19/182D 3D TSV
US9669028 175 Substituted 5-(pyrazin-2-yl)-1H-pyrazolo [3, 4-B] pyridine and pyrazolo [3, 4-B] pyridine derivatives as protein kinase inhibitors ARRIEN PHARMACEUTICALS LLC 05/19/182D 3D TSV
US9670181 87 Substituted 6,7-dialkoxy-3-isoquinolinol derivatives as inhibitors of phosphodiesterase 10 (PDE 10A) ALLERGAN, INC.; EXONHIT THERAPEUTICS SA 05/19/182D 3D TSV
US9670194 71 Substituted aminopyrimidine compounds and methods of use CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD. 05/19/182D 3D TSV
US9670166 297 Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity Boehringer Ingelheim International GmbH 05/19/182D 3D TSV
US9670202 22 Substituted triazolopyridines BAYER PHARMA AKTIENGESELLSCHAFT 05/19/182D 3D TSV
US9670196 13 Thiazole-substituted aminoheteroaryls as Spleen Tyrosine Kinase inhibitors Merck Sharp & Dohme Corp. 05/19/182D 3D TSV
US9670193 138 Trifluoromethyl-oxadiazole derivatives and their use in the treatment of disease Novartis AG 05/19/182D 3D TSV
US9676728 19 2-benzyl-benzimidazole complement factor B inhibitors and uses thereof Novartis AG 04/16/182D 3D TSV
US9675697 203 BET bromodomain inhibitors and therapeutic methods using the same THE REGENTS OF THE UNIVERSITY OF MICHIGAN 04/16/182D 3D TSV
US9676721 112 Compounds and compositions for the inhibition of NAMPT FORMA TM, LLC 04/16/182D 3D TSV
US9676701 287 Cyclopropylamine derivatives useful as LSD1 inhibitors ORYZON GENOMICS, S.A. 04/16/182D 3D TSV
US9676732 74 Ethynyl derivatives HOFFMANN-LA ROCHE INC. 04/16/182D 3D TSV
US9676712 15 Lactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions CAYMAN CHEMICAL COMPANY, INC. 04/16/182D 3D TSV
US9676720 29 Substituted biaryl compound UBE INDUSTRIES, LTD. 04/16/182D 3D TSV
US9675616 13 Arylaminoalcohol-substituted 2,3-dihydroimidazo[1,2-C]quinolines BAYER INTELLECTUAL PROPERTY GMBH 04/12/182D 3D TSV
US9688710 328 Inhibitors of sodium glucose cotransporter 1 Lexicon Pharmaceuticals, Inc. 04/12/182D 3D TSV
US9675614 334 PRMT5 inhibitors and uses thereof Epizyme, Inc. 04/12/182D 3D TSV
US9688696 116 Piperidine/piperazine derivatives Janssen Pharmaceutica N.V. 04/12/182D 3D TSV
US9688816 46 Polyetherimide compositions and methods for the manufacture and use thereof SABIC GLOBAL TECHNOLOGIES B.V. 04/12/182D 3D TSV
US9675612 45 Substituted thiazolopyrimidines BAYER PHARMA AKTIENGESELLSCHAFT 04/12/182D 3D TSV
US9688680 950 Compositions useful for treating disorders related to kit BLUEPRINT MEDICINES CORPORATION 03/27/182D 3D TSV
US9688695 384 Imidazothiadiazole and imidazopyrazine derivatives as protease activated receptor 4 (PAR4) inhibitors for treating platelet aggregation BRISTOL-MYERS SQUIBB COMPANY 03/27/182D 3D TSV
US9688678 37 Oxindole compounds carrying a nitrogen-bound spiro substituent and use thereof for treating vasopressin-related diseases AbbVie Deutschland GmbH & Co. KG 03/27/182D 3D TSV
US9688683 31 Substituted condensed pyrimidine compounds Dalhousie University 03/27/182D 3D TSV
US9688684 278 Substituted tetrazolo[1,5-a]pyrazines as ROR-gamma inhibitors Merck Patent GmbH 03/27/182D 3D TSV
US9688676 65 Tyrosine kinase inhibitors PRINCIPIA BIOPHARMA INC. 03/27/182D 3D TSV
US9688672 450 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH NOVARTIS AG 03/19/182D 3D TSV
US9688668 150 Long chain base sphingosine kinase inhibitors University of Virginia Patent Foundation 03/19/182D 3D TSV
US9688664 8 Modulators of fatty acid amide hydrolase Janssen Pharmaceutica NV 03/19/182D 3D TSV
US9688669 125 Oxazolidinones as modulators of mGluR5 Bristol-Myers Squibb Company 03/19/182D 3D TSV
US9688661 139 Substituted pyrroles active as kinases inhibitors NERVIANO MEDICAL SCIENCES S.R.L. 03/19/182D 3D TSV
US9675593 518 Anti-fibrotic pyridinones INTERMUNE, Inc. 03/16/182D 3D TSV
US9675594 46 Arylpyrrolopyridine derived compounds as LRRK2 inhibitors H. Lundbeck A/S 03/16/182D 3D TSV
US9675539 2 Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives Duke University 03/16/182D 3D TSV
US9675571 28 Inhibitors of indoleamine 2,3-dioxygenase (IDO) Bristol-Myers Squibb Company 03/16/182D 3D TSV
US9688645 25 Macrocyclic urea and sulfamide derivatives as inhibitors of TAFIa SANOFI 03/16/182D 3D TSV
US9675591 9 Methods for treating seizure disorders and pain SRMLSC 03/16/182D 3D TSV
US9675605 83 Substituted naphthyridine and quinoline compounds as MAO inhibitors Dart NeuroScience (Cayman) Ltd. 03/16/182D 3D TSV
US9688642 96 Substituted pyrazines as GPR40 agonists Janssen Pharmaceutica NV 03/12/182D 3D TSV
US9688643 325 Triazine derivative and pharmaceutical composition comprising the same SHIONOGI & CO., LTD. 03/12/182D 3D TSV
US9688638 35 Opioid agonists and uses thereof Nektar Therapeutics 03/11/182D 3D TSV
US9682995 359 Amino-substituted isothiazoles BAYER PHARMA AKTIENGESELLSCHAFT 03/10/182D 3D TSV
US9682993 22 Anticancer compounds St. Jude Children's Research Hospital 03/10/182D 3D TSV
US9682983 326 BMP inhibitors and methods of use thereof The Brigham and Women's Hospital, Inc.; Dept. of Health and Human Services, National Institutes of Health 03/10/182D 3D TSV
US9688615 706 Benzimidazole inhibitors of the sodium channel DEGIACOMO, INTERIM TRUSTEE, MARK G. 03/10/182D 3D TSV
US9688624 12 DP2 antagonist and uses thereof Brickell Biotech, Inc. 03/10/182D 3D TSV
US9687494 21 Iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use Ambit Biosciences 03/10/182D 3D TSV
US9688629 262 Indole carboxamide compounds Bristol-Myers Squibb Company 03/10/182D 3D TSV
US9687479 520 Multisubstituted aromatic compounds as serine protease inhibitors VERSEON CORPORATION 03/10/182D 3D TSV
US9687478 34 Quinuclidine derivatives and medicinal compositions containing the same ALMIRALL, S.A. 03/10/182D 3D TSV
US9687483 5 Treatment of cerebral cavernous malformations and cerebral aneurysms with Rho kinase inhibitors BIOAXONE BIOSCIENCES, INC. 03/10/182D 3D TSV
US9682991 198 Tricyclic compounds for use as kinase inhibitors FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III 03/10/182D 3D TSV
US9682971 220 1,2,5-Substituted benzimidazoles as flap modulators JANSSEN PHARMACEUTICA NV 02/14/182D 3D TSV
US9682980 85 Positive allosteric modulators of mGluR2 Bristol-Myers Squibb Company 02/14/182D 3D TSV
US9682976 324 Protein kinase C inhibitors and uses thereof Rigel Pharmaceuticals, Inc. 02/14/182D 3D TSV
US9682959 6 Ethynyl derivatives HOFFMANN-LA ROCHE INC. 02/13/182D 3D TSV
US9682965 75 Fumagillol heterocyclic compounds and methods of making and using same Zafgen, Inc. 02/13/182D 3D TSV
US9682966 563 Kappa opioid ligands The Scripps Research Institute 02/13/182D 3D TSV
US9682967 50 N-substituted-5-substituted phthalamic acids as sortilin inhibitors H. Lundbeck A/S 02/13/182D 3D TSV
US9682960 137 Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety ENDORECHERCHE, INC. 02/13/182D 3D TSV
US9682969 31 Phthalazinone compounds and methods for the treatment of cystic fibrosis Flatley Discovery Lab, LLC 02/13/182D 3D TSV
US9682968 110 Piperidinyl-indole derivatives complement factor B inhibitors and uses thereof Novartis AG 02/13/182D 3D TSV
US9682963 28 Pyridine derivatives as soft rock inhibitors Redx Pharma PLC 02/13/182D 3D TSV
US9682961 26 Quinazoline derivative CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER 02/13/182D 3D TSV
US9682953 166 Amide compounds, compositions and applications thereof ADVINUS THERAPEUTICS LIMITED 02/07/182D 3D TSV
US9687476 60 Bisaryl-bonded aryltriazolones and use thereof Bayer Intellectual Property GmbH 02/07/182D 3D TSV
US9682141 2516 Combination of kinase inhibitors and uses thereof Intellikine LLC 02/07/182D 3D TSV
US9682957 192 Diamide compounds having muscarinic receptor antagonist and β2 adrenergic receptor agonist activity Theravance Respiratory Company, LLC 02/07/182D 3D TSV
US9682940 502 Indazole derivatives useful as CB-1 inverse agonists Janssen Pharmaceutica NV 02/07/182D 3D TSV
US9682955 280 Quinazoline derivatives useful as CB-1 inverse agonists Janssen Pharmaceutica NV 02/07/182D 3D TSV
US9682910 35 Series of skin-whitening (lightening) compounds Unigen, Inc. 02/07/182D 3D TSV
US9695195 162 5-HT3 receptor antagonists Takeda Pharmaceutical Company Limited 02/06/182D 3D TSV
US9695205 53 Amide compounds for treatment of complement mediated disorders Achillion Pharmaceuticals, Inc. 02/06/182D 3D TSV
US9695197 11 Glycosidase inhibitors and uses thereof Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. 02/06/182D 3D TSV
US9695200 175 Heterocyclic ITK inhibitors for treating inflammation and cancer Confluence Life Sciences, Inc. 02/06/182D 3D TSV
US9695151 90 3,4-dihydro-2H-isoquinoline-1-one and 2,3-dihydro-isoindol-1-one compounds Hoffmann-La Roche Inc. 01/26/182D 3D TSV
US9695152 84 3,4-dihydro-2H-isoquinoline-1-one and 2,3-dihydro-isoindol-1-one compounds Hoffmann-La Roche Inc. 01/26/182D 3D TSV
US9695194 126 Benzoxazinone derivatives for treatment of skin diseases SIXERA PHARMA AB 01/26/182D 3D TSV
US9695172 15 Diazepane derivatives and uses thereof Dana-Farber Cancer Institute, Inc. 01/26/182D 3D TSV
US9695175 51 Highly selective c-Met inhibitors as anticancer agents CB THERAPEUTICS INC. 01/26/182D 3D TSV
US9695181 15 Hydroximic acid derivatives and medical applications therof DOUBLE RIDER MEDICINE CO., LTD. 01/26/182D 3D TSV
US9695174 21 Inhibitor of breast cancer resistance protein (BCRP) Millennium Pharmaceuticals, Inc. 01/26/182D 3D TSV
US9695165 82 Inhibitors of the fibroblast growth factor receptor BLUEPRINT MEDICINES CORPORATION 01/26/182D 3D TSV
US9695179 17 Methods and compositions for inhibition of bromodomain-containing proteins ConverGene LLC 01/26/182D 3D TSV
US9695170 217 Naphthyridine derivatives as inhibitors of Hypoxia inducible factor (HIF) hydroxylase FibroGen, Inc. 01/26/182D 3D TSV
US9695160 36 Piperazine derivatives for treating disorders The University of Nottingham; NewSouth Innovations PTY Limited 01/26/182D 3D TSV
US9695183 702 Substituted 7-azabicycles and their use as orexin receptor modulators JANSSEN PHARMACEUTICA NV 01/26/182D 3D TSV
US9695180 119 Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors Incyte Corporation 01/26/182D 3D TSV
US9695168 158 Substituted imidazo[1,5-α]pyridines and imidazo[1,5-α]pyrazines as LSD1 inhibitors Incyte Corporation 01/26/182D 3D TSV
US9695176 4 Substituted imidazo[1,5-a]pyrazines as CGRP receptor antagonists Bristol-Myers Squibb Company 01/26/182D 3D TSV
US9695167 13 Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors Incyte Corporation 01/26/182D 3D TSV
US9695185 5 Synthetic methods for spiro-oxindole compounds Xenon Pharmaceuticals Inc. 01/26/182D 3D TSV
US9695163 76 Thiazole orexin receptor antagonists MERCK SHARP & DOHME CORP 01/26/182D 3D TSV
US9695149 235 1,2,6-substituted benzimidazoles as flap modulators JANSSEN PHARMACEUTICA NV 01/19/182D 3D TSV
US9695118 394 Benzamide derivative Chugai Seiyaku Kabushiki Kaisha 01/19/182D 3D TSV
US9694016 2555 Biaryl amide compounds as kinase inhibitors NOVARTIS AG 01/19/182D 3D TSV
US9695128 13 Ethynyl derivatives Hoffmann-La Roche Inc. 01/19/182D 3D TSV
US9695132 194 Heteroaryl compounds and uses thereof Celgene CAR LLC; Sanofi 01/19/182D 3D TSV
US9694018 12 IBAT inhibitors for the treatment of liver disease Albireo AB 01/19/182D 3D TSV
US9694015 59 Methods for the treatment of locally advanced breast cancer Celgene Corporation 01/19/182D 3D TSV
US9694024 17 Methods of treating retroviral infections and related dosage regimes Chimerix, Inc. 01/19/182D 3D TSV
US9694012 76 Pyrazol derivatives Hoffmann-La Roche Inc. 01/19/182D 3D TSV
US9694011 6 Substituted pyrazolopyrimidines as kinases inhibitors Jiangsu Medolution Ltd 01/19/182D 3D TSV
US9695131 56 Substituted uracils as chymase inhibitors Bayer Pharma Aktiengesellschaft 01/19/182D 3D TSV
US9693997 356 Antiviral compounds HOFFMANN-LA ROCHE INC. 01/14/182D 3D TSV
US9693992 251 IRE-1α inhibitors MannKind Corporation 01/14/182D 3D TSV
US9694002 648 Substituted benzamides and methods of use thereof GENENTECH, INC.; XENON PHARMACEUTICALS INC. 01/14/182D 3D TSV
US9527838 54 2-pyridinecarboxamide derivatives, compositions containing such compounds, and methods of treatment Merck Sharp & Dohme Corp. 12/04/172D 3D TSV
US9527839 25 Benzimidazole tetrahydropyran derivatives Merck Sharp & Dohme Corp. 12/04/172D 3D TSV
US9533969 6 Materials and method for inhibiting replication protein A and uses thereof Indiana University Research and Technology Corporation 12/04/172D 3D TSV
US9532990 119 Polyfluorinated compounds acting as bruton tyrosine kinase inhibitors Zhejiang DTRM Biopharma Co. Ltd. 12/04/172D 3D TSV
US9504692 48 Selective inhibition of MALT1 protease by phenothiazine derivatives HELMHOLTZ ZENTRUM MUNCHEN, DEUTSCHES FORSCHUNGSZENTRUM FUR GESUNDHEIT UND UMWELT (GMBH) 12/04/172D 3D TSV
US9533989 123 Substituted pyrimidine-5-carboxamides as spleen tyrosine kinase inhibitors Ziarco Pharma Ltd. 12/04/172D 3D TSV
US9533985 193 Sulfonamide derivative and medicinal use thereof EA Pharma Co., Ltd. 12/04/172D 3D TSV
US9522881 71 Hydroxyindole carboxylic acid based inhibitors for oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) Indiana University Research and Technology Corporation 11/27/172D 3D TSV
US9512115 58 Inhibitors PROBIODRUG AG 11/27/172D 3D TSV
US9505766 158 Kinase inhibitors THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 11/27/172D 3D TSV
US9522910 16 Protein kinase inhibitors (variants), use thereof in treating oncological diseases and a pharmaceutical composition based thereon OBSHCHESTVO S OGRANICHENNOY OTVETSTVENNOSTYOU “FUSION PHARMA” 11/27/172D 3D TSV
US9505762 338 Purine derivatives as CB2 receptor agonists HOFFMANN-LA ROCHE INC. 11/27/172D 3D TSV
US9512141 84 Pyrazine derivatives as CB2 receptor agonists HOFFMANN-LA ROCHE INC. 11/27/172D 3D TSV
US9512132 76 Pyrazole compounds as CB2 agonists Hoffmann-La Roche Inc. 11/27/172D 3D TSV
US9522886 195 Pyridine derivatives HOFFMANN-LA ROCHE INC. 11/27/172D 3D TSV
US9505749 527 Quinazolinone compounds and derivatives thereof AMGEN INC. 11/27/172D 3D TSV
US9505780 114 Thienopyranones as kinase and epigenetic inhibitors SignalRx Pharmaceuticals, Inc. 11/27/172D 3D TSV
US9512121 47 [1,2,4] triazol [4,3-A] pyridine derivative, preparation method therefor or medical application thereof Jiangsu Hansoh Pharmaceutical Co., Ltd. 11/27/172D 3D TSV
US9499492 130 4-(ortho)-fluorophenyl-5-fluoropyrimidin-2-yl amines containing a sulfoximine group Bayer Pharma Aktiengesellschaft 11/20/172D 3D TSV
US9499502 733 5-substituted iminothiazines and their mono- and dioxides as BACE inhibitors, compositions, and their use Merck Sharp & Dohme Corp. 11/20/172D 3D TSV
US9512084 40 Amino pyrimidine derivatives Novartis AG 11/20/172D 3D TSV
US9499547 110 Amino-substituted imidazopyridazines BAYER INTELLECTUAL PROPERTY GMBH 11/20/172D 3D TSV
US9493490 60 Boron-containing small molecules Anacor Pharmaceuticals, Inc. 11/20/172D 3D TSV
US9493486 113 Diazaspirocycloalkane and azaspirocycloalkane Hoffmann-La Roches Inc. 11/20/172D 3D TSV
US9505745 110 Enhancer of zeste homolog 2 inhibitors GlaxoSmithKline Intellectual Property (No. 2) Limited 11/20/172D 3D TSV
US9526727 30 Inhibitors of beta-secretase Vitae Pharmaceutical, Inc. 11/20/172D 3D TSV
US9499482 247 Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists Bristol-Myers Squibb Company 11/20/172D 3D TSV
US9512114 52 Substituted aminopyrimidine compounds and methods of use CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD. 11/20/172D 3D TSV
US9512126 25 Substituted imidazopyridazines Bayer Intellectual Property GmbH 11/20/172D 3D TSV
US9512169 23 3-substituted estra-1,3,5(10),16-tetraene derivatives, methods for the production thereof, pharmaceutical preparations containing same, and use thereof for the production of medicaments BAYER PHARMA AKTIENGESELLSCHAFT 11/13/172D 3D TSV
US9512068 14 Augmenting moieties for anti-inflammatory compounds RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY; LEHIGH UNIVERSITY 11/13/172D 3D TSV
US9493448 168 Cycloalkane derivatives DAIICHI SANKYO COMPANY, LIMITED 11/13/172D 3D TSV
US9511061 6 Incontinence treatment methods IXALTIS 11/13/172D 3D TSV
US9505753 69 Inhibitors of D-amino acid oxidase THE JOHNS HOPKINS UNIVERSITY 11/13/172D 3D TSV
US9512082 7 Inhibitors of glutaminyl cyclase PROBIODRUG AG 11/13/172D 3D TSV
US9493446 1134 Orexin receptor antagonists which are [ortho bi-(hetero-)aryl]-[2-(meta bi-(hetero-)aryl)-pyrrolidin-1-yl]-methanone derivatives ACTELION PHARMACEUTICALS LTD. 11/13/172D 3D TSV
US9512065 5 Polymorphs of N-[(R)-1-[(S)-1-(4-aminomethyl-benzylcarbamoyl)-2-phenyl-ethylcarbamoyl]-2-(4-ethoxy-phenyl)-ethyl]-benzamide hydrochloride Kalvista Pharmaceuticals Limited 11/13/172D 3D TSV
US9493485 178 Spirocyclic dihydro-thiazine and dihydro-oxazine BACE inhibitors, and compositions and uses thereof Imago Pharmaceuticals, Inc. 11/13/172D 3D TSV
US9505786 59 Substituted annulated triazines and use thereof BAYER PHARMA AKTIENGESELLSCHAFT; BAYER INTELLECTUAL PROPERTY GMBH 11/13/172D 3D TSV
US9522888 952 Substituted bicyclic compounds Bristol-Myers Squibb Company 11/13/172D 3D TSV
US9512130 4 Substituted imidazopyridazines BAYER PHARMA AKTIENGESELLSCHAFT 11/13/172D 3D TSV
US9493441 222 Acyclic cyanoethylpyrazoles as janus kinase inhibitors Merck Sharp & Dohme Corp. 11/06/172D 3D TSV
US9489013 194 C6-azaspiro iminothiadiazine dioxides as bace inhibitors, compositions, and their use Merck Sharp & Dohme Corp. 11/06/172D 3D TSV
US9493440 239 Compounds inhibiting leucine-rich repeat kinase enzyme activity Merck Sharp & Dohme Corp. 11/06/172D 3D TSV
US9493432 214 Cyclopentylbenzamide derivatives and their use for the treatment of psychotic and cognitive disorders Takeda Pharmaceuticals Company Limited 11/06/172D 3D TSV
US9487511 375 Cyclopropanamine compound and use thereof Takeda Pharmaceutical Company Limited 11/06/172D 3D TSV
US9522883 1 Glycosidase inhibitors and uses thereof Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. 11/06/172D 3D TSV
US9505736 16 Histone deacetylase inhibitors and compositions and methods of use thereof CHDI Foundation, Inc. 11/06/172D 3D TSV
US9493435 182 IRE-1α inhibitors MannKing Corporation 11/06/172D 3D TSV
US9492453 77 Protein kinase B inhibitors AstraZeneca AB 11/06/172D 3D TSV
US9505773 18 Rapamycin analogues and their pharmaceutical use Isomerase Therapeutics Ltd. 11/06/172D 3D TSV
US9504684 11 Syk inhibitors Gilead Sciences, Inc. 11/06/172D 3D TSV
US9487512 159 (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors Oryzon Genomics S.A. 10/30/172D 3D TSV
US9487490 63 3-cyclohexenyl and cyclohexyl substituted indole and indazole compounds as RORgammaT inhibitors and uses thereof Merck Sharp & Dohme Corp. 10/30/172D 3D TSV
US9481672 253 Bicyclically substituted uracils and the use thereof Bayer Pharma Aktiengesellschaft 10/30/172D 3D TSV
US9487483 128 Complement pathway modulators and uses thereof Novartis AG 10/30/172D 3D TSV
US9505754 4 Compound useful for the treatment of degenerative and inflammatory diseases GALAPAGOS NV 10/30/172D 3D TSV
US9487462 114 Inhibitors of matrix metalloproteinases PharmaHungary 2000 Kft.; TargetEx Kft. 10/30/172D 3D TSV
US9481648 347 Kinase inhibitors Respivert Limited; Topivert Pharma Limited 10/30/172D 3D TSV
US9505743 3 Matrix metalloproteinase inhibitors and methods for the treatment of pain and other diseases TBA 10/30/172D 3D TSV
US9487501 114 Pyrazole carboxamide compounds and uses thereof Hoffmann-La Roche Inc. 10/30/172D 3D TSV
US9475815 228 Substituted benzothienyl-pyrrolotriazines and uses thereof BAYER INTELLETUAL PROPERTY GMBH 10/30/172D 3D TSV
US9487488 60 Sulfonamide compound MITSUBISHI TANABE PHARMA CORPORATION 10/30/172D 3D TSV
US9481688 24 (Thieno[2,3-b][1,5]benzoxazepin-4-yl)piperazin-1-yl compounds as dual activity H1 inverse agonists/5-HT2A antagonists Eli Lilly and Company 10/23/172D 3D TSV
US9499493 51 2,4-pyrimidinediamine compounds and their uses Rigel Pharmaceuticals, Inc. 10/23/172D 3D TSV
US9499570 14 Boron containing small molecules Anacor Pharmaceuticals, Inc. 10/23/172D 3D TSV
US9499561 46 Fused pyrimidine compound, and preparation method, intermediate, composition, and uses thereof Shanghai Yingli Pharmaceutical Co., Ltd. 10/23/172D 3D TSV
US9499486 7 Kinase inhibitor Respivert Limited; Topivert Pharma Limited 10/23/172D 3D TSV
US9499523 63 Phosphatidylinositol 3-kinase inhibitors GILEAD SCIENCES, INC. 10/23/172D 3D TSV
US9475817 402 Pyrazole substituted imidazopyrazines as casein kinase 1 d/e inhibitors Bristol-Myers Squibb Company 10/23/172D 3D TSV
US9475819 702 Substituted 7-azabicycles and their use as orexin receptor modulators Janssen Pharmaceutica NV 10/23/172D 3D TSV
US9481682 221 Substituted benzamides and substituted pyridinecarboxamides as Btk inhibitors MERCK SHARP & DOHME CORP. 10/23/172D 3D TSV
US9499534 42 Thiazole-substituted aminopyrimidines as spleen tyrosine kinase inhibitors Merck Sharp & Dohme Corp. 10/23/172D 3D TSV
US9475813 268 Tricyclic pyrrolopyridine compound, and JAK inhibitor Nissan Chemical Industries, Ltd. 10/23/172D 3D TSV
US9469597 210 (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors Oryzon Genomics S.A. 10/16/172D 3D TSV
US9505765 36 4-alkoxy/aralkoxy-5-substituted-pyrrolopyrimidine compounds as TAK1 inhibitors in disease treatment CONFLUENCE LIFE SCIENCES INC. 10/16/172D 3D TSV
US9499542 46 Arylpyrrolopyridine derived compounds as LRRK2 inhibitors H. Lundbeck A/S; Vernalis (R&D) Ltd. 10/16/172D 3D TSV
US9475775 160 Benzazepine dicarboxamide compounds Hoffmann-La Roche Inc. 10/16/172D 3D TSV
US9493483 6 Benzo [C] isoxazoloazepine bromodomain inhibitors and uses thereof Constellation Pharmaceuticals, Inc. 10/16/172D 3D TSV
US9487554 62 Estra-1,3,5(10),16-tetraene-3-carboxamide derivatives, processes for their preparation, pharmaceutical preparations comprising them and their use for preparing medicaments Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft 10/16/172D 3D TSV
US9469631 130 N-cyclopropyl-N-piperidinyl-amides, pharmaceutical compositions containing them, and uses thereof Boehringer Ingelheim International GmbH 10/16/172D 3D TSV
US9464084 843 P2X7 modulators Janssen Pharmaceutica NV 10/16/172D 3D TSV
US9505734 2 Phenyl C-glucoside derivative containing deoxyglucose structure, preparation method and use thereof Tianjin Institute of Pharmaceutical Research 10/16/172D 3D TSV
US9468661 123 Pyrrolidine derivatives and their use as complement pathway modulators Novartis AG 10/16/172D 3D TSV
US9493412 34 Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors Bristol-Myers Squibb Company 10/16/172D 3D TSV
US9493472 34 Substituted benzoxazoles Bayer Pharma Aktiengesellschaft 10/16/172D 3D TSV
US9481677 37 Biaryl ether sulfonamides and their use as therapeutic agents XENON PHARMACEUTICALS INC. 10/10/172D 3D TSV
US9493457 3 4,5,6,7-tetrahyroimidazo[4,5-c]pyridine compounds Proximagen Limited 10/09/172D 3D TSV
US9481673 141 6-alkynyl-pyridine derivatives Boehringer ingelheim International GmbH 10/09/172D 3D TSV
US9493431 44 Apoptosis-inducing agent for the treatment of cancer and immune and autoimmune diseases ABBVIE INC. 10/09/172D 3D TSV
US9493430 41 Biaryl- or heterocyclic biaryl-substituted cyclohexene derivative compounds as CETP inhibitors Chong Kun Dang Pharmaceutical Corp. 10/09/172D 3D TSV
US9493474 60 Inhibitors of the renal outer medullary potassium channel Merck Sharp & Dohme Corp. 10/09/172D 3D TSV
US9458201 162 Melanocortin receptor-specific heptapeptides Palatin Technologies, Inc. 10/09/172D 3D TSV
US9458171 572 Pyrrolidinyl sulfone RORγ modulators Bristol-Myers Squibb Company 10/09/172D 3D TSV
US9505739 11 Spiropyrrolidine beta-secretase inhibitors for the treatment of alzheimer's disease Merck Sharp & Dohme Corp. 10/09/172D 3D TSV
US9464092 229 Transient protection of normal cells during chemotherapy G1 Therapeutics, Inc. 10/09/172D 3D TSV
US9459250 254 Use of T1R3 venus flytrap region polypeptide to screen for taste modulators SENOMYX, INC. 10/09/172D 3D TSV
US9464076 131 Benzothiophene derivative Daiichi Sankyo Company, Limited 10/02/172D 3D TSV
US9487494 9 Cyclic hydrocarbon compounds for the treatment of diseases LEO PHARMA A/S 10/02/172D 3D TSV
US9481685 8 Imaging neuroinflammation GE Healthcare Limited 10/02/172D 3D TSV
US9493447 14 Optically active PDE10 inhibitor Omeros Corporation 10/02/172D 3D TSV
US9480684 35 Orvinol and thevinol derivatives useful in the treatment of anxiety or a compulsive disorder The University of Bath 10/02/172D 3D TSV
US9458110 632 Phenylpyrazole derivatives as potent ROCK1 and ROCK2 inhibitors Bristol-Myers Squibb Company 10/02/172D 3D TSV
US9458172 180 Pyridinyl and pyrimidinyl sulfoxide and sulfone derivatives TBA 10/02/172D 3D TSV
US9493429 9 Substituted benzoxazoles and methods of use thereof GENENTECH, INC.; XENON PHARMACEUTICALS INC. 10/02/172D 3D TSV
US9458113 187 Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity Boehringer Ingelheim International GmbH 10/02/172D 3D TSV
US9458176 245 Tetrahydroimidazo(1,5-D)[1,4]oxazepine derivative Eisai R&D Management Co., Ltd. 10/02/172D 3D TSV
US9469608 44 Thrombin inhibitors Merck Sharp & Dohme Corp. 10/02/172D 3D TSV
US9452986 683 6-heteroaryloxy- or 6-aryloxy-quinoline-2-carboxamides and method of use AbbVie Inc. 09/25/172D 3D TSV
US9453031 272 Chemical entities Fundación Centro Nacional de Investigaciones Oncológicas Carlos III 09/25/172D 3D TSV
US9475814 83 Chiral N-acyl-5,6,7(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor mediated disorders and chiral synthesis thereof Euroscreen S.A. 09/25/172D 3D TSV
US9475806 21 Complement factor B inhibitors and uses there of Novartis AG 09/25/172D 3D TSV
US9452990 131 Complement pathway modulators and uses thereof NOVARTIS AG 09/25/172D 3D TSV
US9464060 136 Compounds Takeda Pharmaceutical Company Limited 09/25/172D 3D TSV
US9468642 46 Imidazopyrazines BAYER INTELLECTUAL PROPERTY GMBH 09/25/172D 3D TSV
US9447148 197 Melanocortin-1 receptor-specific cyclic peptides Palatin Technologies, Inc. 09/25/172D 3D TSV
US9469653 23 Pharmaceutical compositions for preventing or treating degenerative brain disease and method of screening the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 09/25/172D 3D TSV
US9452998 274 Protein kinase C inhibitors and methods of their use NOVARTIS AG 09/25/172D 3D TSV
US9481668 1 Quinoline inhibitor of the macrophage stimulating 1 receptor MSTR1 Merck Patent GmbH 09/25/172D 3D TSV
US9475779 63 Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity Boehringer Ingelheim International GmbH 09/25/172D 3D TSV
US9475809 16 Substituted oxopyridine derivatives and use thereof as factor xia/plasma Bayer Pharma Aktiengesellschaft 09/25/172D 3D TSV
US9469613 4 (N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide GILEAD SCIENCES, INC. 09/18/172D 3D TSV
US9464044 101 Compound having ability to inhibit 11Beta-HSD1 enzyme or pharmaceutically acceptable salt thereof, method for producing same, and pharmaceutical composition containing same as active ingredient AHN-GOOK PHARMACEUTICAL CO., LTD.; BAMICHEM CO., LTD; INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION 09/18/172D 3D TSV
US9447087 91 Galactokinase inhibitors for the treatment and prevention of associated diseases and disorders UNIVERSITY OF UTAH RESEARCH FOUNDATION 09/18/172D 3D TSV
US9469644 7 Inhibitors of Bruton's tyrosine kinase Hoffmann-La Roche Inc. 09/18/172D 3D TSV
US9469639 14 Naphthylurea derivatives and medical applications thereof Radiant Pharma & Tech. Co., Ltd. 09/18/172D 3D TSV
US9469627 3 Phenyloxadiazole derivatives as PGDS inhibitors Sanofi 09/18/172D 3D TSV
US9434697 144 Pyrimidine FGFR4 inhibitors EISAI R&D MANAGEMENT CO., LTD. 09/18/172D 3D TSV
US9464103 12 Spirocyclic sulfones as gamma secretase inhibitors MERCK SHARP & DOHME CORP. 09/18/172D 3D TSV
US9434727 247 Substituted 4-phenylpiperidines, their preparation and use THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 09/18/172D 3D TSV
US9447038 205 Substituted B-amino acid derivatives as CXCR3 receptor antagonists Sanofi 09/18/172D 3D TSV
US9452980 625 Substituted benzamides Hoffmann-La Roche Inc. 09/18/172D 3D TSV
US9447106 218 Substituted pyrazolo[1,5-a]pyrimidines as bruton's tyrosine kinase modulators BeiGene, Ltd. 09/18/172D 3D TSV
US9475795 111 Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases Takeda Pharmaceutical Company Limited 09/18/172D 3D TSV
US9457039 24 2′-disubstituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases Merck Sharp & Dohme Corp. 09/11/172D 3D TSV
US9434725 762 5-azaindazole compounds and methods of use F. HOFFMANN-LA ROCHE AG 09/11/172D 3D TSV
US9458145 111 Benzimidazole derivatives as bromodomain inhibitors Gilead Sciences, Inc. 09/11/172D 3D TSV
US9453034 72 C2-azaspiro iminothiazine dioxides as BACE inhibitors, compositions, and their use Merck Sharp & Dohme Corp. 09/11/172D 3D TSV
US9458136 1 Crystalline forms and processes for the preparation of cannabinoid receptor modulators Arena Pharmaceuticals, Inc. 09/11/172D 3D TSV
US9458135 60 Dihydroquinoline-2-one derivatives Hoffmann-La Roche Inc. 09/11/172D 3D TSV
US9464062 6 Disubstituted oxazolidin-2-ones 5-hydroxytryptamine receptor 2B activity modulators TEMPLE UNIVERSITY—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 09/11/172D 3D TSV
US9458140 29 Furanone compounds as kinase inhibitors Eternity Bioscience Inc. 09/11/172D 3D TSV
US9453038 42 Glucokinase activator compounds, compositions containing such compounds, and methods of treatment Merck Sharp & Dohme Corp. 09/11/172D 3D TSV
US9453048 38 IAP antagonists Bristol-Myers Squibb Company 09/11/172D 3D TSV
US9458105 10 Inhibitors of Bruton's tyrosine kinase Hoffmann-La Roche Inc. 09/11/172D 3D TSV
US9464073 16 Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors Acetylon Pharmaceuticals, Inc. 09/11/172D 3D TSV
US9464081 23 Pyrrolidine derivatives and their use as complement pathway modulators Novartis AG 09/11/172D 3D TSV
US9434711 709 Sulfonamides as TRPM8 modulators Janssen Pharmaceutica, N.V. 09/11/172D 3D TSV
US9463192 43 Trk-inhibiting compound ONO PHARMACEUTICAL CO., LTD. 09/11/172D 3D TSV
US9434719 783 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH NOVARTIS AG 09/05/172D 3D TSV
US9453017 12 Antiviral therapies with phospholipase D inhibitors Vanderbilt University 09/05/172D 3D TSV
US9447029 38 Fluorinated arylalkylaminocarboxamide derivatives NEWRON PHARMACEUTICALS S.P.A. 09/05/172D 3D TSV
US9447090 34 Imidazopyridine compounds Astellas Pharma Inc. 09/05/172D 3D TSV
US9447085 33 Iminothiadiazine dioxides containing a thioamide, amidine, or amide oxime group as BACE inhibitors, compositions, and their use Merck Sharp & Dohme Corp. 09/05/172D 3D TSV
US9446026 20 Ocular formulations for drug-delivery to the posterior segment of the eye PanOptica, Inc. 09/05/172D 3D TSV
US9434733 75 PDE9 inhibitors with imidazo triazinone backbone H. LUNDBECK A/S 09/05/172D 3D TSV
US9447092 48 Pharmaceutically active compounds CANCER RESEARCH TECHNOLOGY LIMITED 09/05/172D 3D TSV
US9447091 40 Protein kinase inhibitors ORION CORPORATION 09/05/172D 3D TSV
US9447095 30 Pyrimidine derivatives as phosphodiesterase 10 inhibitors (PDE-10) PALOBIOFARMA S.L. 09/05/172D 3D TSV
US9453018 22 Pyrimidinones as factor XIa inhibitors Bristol-Myers Squibb Company 09/05/172D 3D TSV
US9453021 17 Pyrimidodiazepinone compound Kyowa Hakko Kirin Co., Ltd. 09/05/172D 3D TSV
US9434724 377 Quinuclidines for modulating alpha 7 activity ALPHARMAGEN, LLC 09/05/172D 3D TSV
US9453023 39 Substituted phenyl cycloalkyl pyrrolidine (piperidine) spirolactams and amides, preparation and therapeutic use thereof Sanofi 09/05/172D 3D TSV
US9452985 8 Tau imaging probe GE Healthcare Limited 09/05/172D 3D TSV
US9428508 324 2,4-diamino-6,7-dihydro-5H-pyrrolo[2,3]pyrimidine derivatives as FAK/Pyk2 inhibitors Centaurus BioPharma Co., Ltd. 08/28/172D 3D TSV
US9446130 25 BTK inhibitors Merck Sharp & Dohme Corp. 08/28/172D 3D TSV
US9433609 144 Benzimidazole-imidazole derivatives Janssen Sciences Ireland UC 08/28/172D 3D TSV
US9428514 208 Bromodomain inhibitors AbbVie Inc. 08/28/172D 3D TSV
US9446044 107 DYRK1 inhibitors and uses thereof DIAXONHIT 08/28/172D 3D TSV
US9447132 2 Highly active nucleoside derivative for the treatment of HCV Achillion Pharmaceuticals, Inc. 08/28/172D 3D TSV
US9428503 315 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating Cancer AstraZeneca AB 08/28/172D 3D TSV
US9428511 152 Imidazopyridazine JAK3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases Bristol-Myers Squibb Company 08/28/172D 3D TSV
US9434692 4 Pyrazole derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto Arena Pharmaceuticals, Inc. 08/28/172D 3D TSV
US9433622 330 Pyrimidine compounds useful in the treatment of diseases mediated by IKKE and/or TBK1 mechanisms Case Western Reserve University 08/28/172D 3D TSV
US9447057 29 Schiff bases of thiazoles: a new class of ureases inhibitors TBA 08/28/172D 3D TSV
US9434690 357 Substituted oxopyridine derivatives and use thereof in the treatment of cardiovascular disorders Bayer Pharma Aktiengesellschaft 08/28/172D 3D TSV
US9434693 45 Substituted pyrazoles as N-type calcium channel blockers Janssen Pharmaceutica NV 08/28/172D 3D TSV
US9447114 29 Thieno- and furo[2,3-d]pyrimidine-2,4[1H,3H]-dione derivatives Hydra Biosciences, Inc. 08/28/172D 3D TSV
US9428513 29 Triazolopyrazine Boehringer Ingelheim International GmbH 08/28/172D 3D TSV
US9428505 22 Hydantoin derivative Chugai Seiyaku Kabushiki Kaisha 08/24/172D 3D TSV
US9428469 30 Antiviral compounds HOFFMANN-LA ROCHE 08/22/172D 3D TSV
US9447055 2 α-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof Merck Serono S.A. 08/21/172D 3D TSV
US9428456 501 1-[m-carboxamido(hetero)aryl-methyl]-heterocyclyl-carboxamide derivatives ACTELION PHARMACEUTICALS LTD 08/21/172D 3D TSV
US9428504 172 7-hydroxy-spiropipiperidine indolinyl antagonists of P2Y1 receptor Bristol-Myers Squibb Company 08/21/172D 3D TSV
US9428500 117 Alpha-carbolines for the treatment of cancer UNIVERSITA DEGLI STUDI DI MILANO—BICOCCA; UNIVERSITE DE GENEVE; UNIVERSITE CLAUDE BERNARD—LYON 08/21/172D 3D TSV
US9427428 138 Benzimidazole-imidazole derivatives Janssen Sciences Ireland UC 08/21/172D 3D TSV
US9428501 53 Bicyclic nitrogen-containing aromatic heterocyclic amide compound Astellas Pharma Inc. 08/21/172D 3D TSV
US9446064 9 Combination therapy for treating cancer Epizyme, Inc. 08/21/172D 3D TSV
US9428502 338 Heterocyclic modulators of lipid synthesis 3-V Biosciences, Inc. 08/21/172D 3D TSV
US9427440 69 Macrocyclic indole derivatives useful as hepatitis C virus inhibitors Janssen Sciences Ireland UC 08/21/172D 3D TSV
US9428460 40 N-[4-(quinolin-4-yloxy)cyclohexyl(methyl)](hetero)arylcarboxamides as androgen receptor antagonists, production and use thereof as medicinal products BAYER PHARMA AKTIENGESELLSCHAFT 08/21/172D 3D TSV
US9428478 66 Piperazine derivatives, compositions, and uses related thereto Emory University 08/21/172D 3D TSV
US9428476 17 S-imino-S-oxo-iminothiadiazine compounds as BACE inhibitors, compositions, and their use Merck Sharp & Dohme Corp. 08/21/172D 3D TSV
US9428492 54 Secondary alcohol substituted triazoles as PDE10 inhibitors Merck Sharp & Dohme Corp. 08/21/172D 3D TSV
US9428491 12 Substituted azoles, antiviral active component, pharmaceutical composition, method for preparation and use thereof TBA 08/21/172D 3D TSV
US9422293 771 Tetrahydro-pyrimidoazepines as modulators of TRPV1 Janssen Pharmaceutica NV 08/21/172D 3D TSV
US9422331 108 2-oxo-2,3,4,5-tetrahydro-1 H-benzo[B]diazepines and their use in the treatment of cancer HOFFMANN-LA ROCHE INC. 08/14/172D 3D TSV
US9422332 92 Azaheterocycles as BIR2 and/or BIR3 inhibitors HOFFMANN-LA ROCHE INC. 08/14/172D 3D TSV
US9428447 29 Bis-(aryl/heteroaryl)-methylene compounds, pharmaceutical compositions containing same and their use for treating cancer The Royal Institution for the Advancement of Learning/McGill University 08/14/172D 3D TSV
US9415055 223 Cyclic amines H. Lundbeck A/S 08/14/172D 3D TSV
US9422318 37 Epoxyeicosatrienoic acid analogs and methods of making and using the same The Medical College of Wisconsin, Inc.; The Board of Regents of the University of Texas System 08/14/172D 3D TSV
US9427442 58 Fluoroalkyl and fluorocycloalkyl 1,4-benzodiazepinone compounds Bristol-Myers Squibb Company 08/14/172D 3D TSV
US9422240 52 Partially saturated nitrogen-containing heterocyclic compound TAISHO PHARMACEUTICAL CO., LTD 08/14/172D 3D TSV
US9422255 40 S-imino-S-oxo-iminothiazine compounds as BACE inhibitors, compositions, and their use Merck Sharp & Dohme Corp. 08/14/172D 3D TSV
US9422299 205 Substituted [1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists EUROSCREEN SA 08/14/172D 3D TSV
US9416132 120 Substituted imidazo[1,2-b]pyridazines as protein kinase inhibitors Tolero Pharmaceuticals, Inc. 08/14/172D 3D TSV
US9422235 171 Sulfonamide derivatives with therapeutic indications Pharmos Corporation 08/14/172D 3D TSV
US9422290 38 Triazolopyridazine Boehringer Ingelheim International GmbH 08/14/172D 3D TSV
US9422297 65 Tricyclic compounds having cytostatic and/or cytotoxic activity and methods of use thereof Duquesne University of the Holy Ghost 08/14/172D 3D TSV
US9416129 244 Tricyclic substituted thiadiazine dioxide compounds as BACE inhibitors, compositions and their use Merck Sharp & Dohme Corp. 08/14/172D 3D TSV
US9422277 170 Tricyclic substituted thiadiazine dioxide compounds as BACE inhibitors, compositions and their use Merck Sharp & Dohme Corp. 08/14/172D 3D TSV
US9394331 44 2′-spiro-nucleosides and derivatives thereof useful for treating hepatitis C virus and dengue virus infections Gilead Pharmasset LLC 08/07/172D 3D TSV
US9409892 368 4-hydroxy-isoquinoline compounds as HIF hydroxylase inhibitors FibroGen, Inc. 08/07/172D 3D TSV
US9416154 45 5′-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases Merck Sharp & Dohme Corp. 08/07/172D 3D TSV
US9428465 17 Acid ceramidase inhibitors and their use as medicaments Fondazione Istituto Italiano Di Technologia 08/07/172D 3D TSV
US9409895 69 Autotaxin inhibitors Novartis AG 08/07/172D 3D TSV
US9409908 443 Dihydropyridone p1 as factor XIa inhibitors Bristol-Myers Squibb Company 08/07/172D 3D TSV
US9409888 53 Dimeric compounds Hoffmann-La Roche Inc. 08/07/172D 3D TSV
US9422333 28 HCV protease inhibitors and uses thereof Celgene Avilomics Research, Inc. 08/07/172D 3D TSV
US9409917 118 Heterocyclic amide derivatives as P2X7 receptor antagonists ACTELION PHARMACEUTICALS LTD. 08/07/172D 3D TSV
US9421177 72 Imidamide sphingosine kinase inhibitors University of Virginia Patent Foundation 08/07/172D 3D TSV
US9409907 205 Inhibitor compounds Cancer Research Technology Limited 08/07/172D 3D TSV
US9416123 85 Kinase modulators for the treatment of cancer Synovo GmbH 08/07/172D 3D TSV
US9428466 9 Methods for reducing uric acid levels using barbiturate derivatives TBA 08/07/172D 3D TSV
US9416139 72 Spiro ring compound as hepatitis C virus (HCV) inhibitor and uses thereof SUNSHINE LAKE PHARMA CO., LTD. 08/07/172D 3D TSV
US9409915 90 Substituted aza-bicyclic imidazole derivatives useful as TRPM8 receptor modulators Janssen Pharmaceutica NV 08/07/172D 3D TSV
US9422307 17 2,4,7-substituted thieno[3,2-d]pyrimidine compounds as protein kinase inhibitors KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 08/01/172D 3D TSV
US9422324 8 6-substituted demethyl-estradiol derivatives as selective ER-β agonists Endece LLC 08/01/172D 3D TSV
US9422312 21 Azabenzimidazole derivatives Boehringer Ingelheim International GmbH 08/01/172D 3D TSV
US9422273 40 Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response ALLERGAN, INC. 08/01/172D 3D TSV
US9422243 55 3-phenyl-isoquinolin-1(2H)-one derivatives as PARP-1 inhibitors NERVIANO MEDICAL SCIENCES S.R.L. a corporation 07/31/172D 3D TSV
US9403813 270 Azetidine amide derivatives as orexin receptor antagonists ACTELION PHARMACEUTICALS LTD. 07/31/172D 3D TSV
US9403843 72 Cysteine protease inhibitors and uses thereof THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK; THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 07/31/172D 3D TSV
US9422263 19 Fluoro-substituted 3,5-dicyano-4-(1H-indazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine derivatives and methods of use thereof BAYER PHARMA AKTIENGESELLSCHAFT 07/31/172D 3D TSV
US9422261 11 Heterocyclic resorcinol derivatives, preparation of same and cosmetic uses thereof PIERRE FABRE DERMO-COSMETIQUE 07/31/172D 3D TSV
US9422231 5 Method for inhibiting Trypanosoma cruzi HOWARD UNIVERSITY 07/31/172D 3D TSV
US9403808 195 Pyrazine derivatives Hoffmann-La Roche Inc. 07/31/172D 3D TSV
US9409882 96 Pyridine derivatives Hoffmann-La Roche Inc. 07/31/172D 3D TSV
US9409866 620 Pyridine-2-amides useful as CB2 agonists HOFFMANN-LA ROCHE INC. 07/31/172D 3D TSV
US9409924 26 Selective glycosidase inhibitors and uses thereof Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp. 07/31/172D 3D TSV
US9403767 182 Substituted 4-aminocyclohexane derivatives GRUENENTHAL GMBH 07/31/172D 3D TSV
US9403801 81 Substituted heteroaryl compounds and methods of use CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD. 07/31/172D 3D TSV
US9394309 198 Substituted phenylimidazopyrazoles and their use Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH 07/31/172D 3D TSV
US9416127 72 Triazole carboxamides and uses thereof Hoffmann-La Roche Inc. 07/31/172D 3D TSV
US9394311 136 Triazolo compounds as PDE10 inhibitors Hoffmann-La Roche Inc. 07/31/172D 3D TSV
US9403810 48 Carboxamide derivatives Novartis AG 07/25/172D 3D TSV
US9409931 8 3-O-acyl-ingenol analogues LEO LABORATORIES LIMITED 07/24/172D 3D TSV
US9408863 13 5′-substituted nucleoside analogs and methods of use thereof for the treatment of viral diseases Merck Sharp & Dohme Corp. 07/24/172D 3D TSV
US9409845 22 Alpha-(3,5-dimethoxybenzylidene)-alpha′-hydrocarbyl methylene cyclic ketone and preparation method thereof PHARMAXYN LABORATORIES LTD. 07/24/172D 3D TSV
US9394297 934 Amides as pim inhibitors AMGEN INC. 07/24/172D 3D TSV
US9403846 28 Carbocyclic- and heterocyclic-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds Pfizer Inc. 07/24/172D 3D TSV
US9403833 17 Carboxamide derivatives Novartis AG 07/24/172D 3D TSV
US9409900 4 Compound for increasing kinase active and application thereof FUJIAN HAIXI PHARMACEUTICALS, INC.; BETTA PHARMACUETICALS CO., LTD. 07/24/172D 3D TSV
US9416126 394 Compounds inhibiting leucine-rich repeat kinase enzyme activity Merck Sharp & Dohme Corp. 07/24/172D 3D TSV
US9403803 15 Indole-3-carboxamides as kinase inhibitors Allergan, Inc. 07/24/172D 3D TSV
US9403768 24 Indolines Hoffmann-La Roche Inc. 07/24/172D 3D TSV
US9409868 44 Inhibitors of rho associated protein kinases (ROCK) and methods of use H. Lee Moffin Cancer Center and Research Institute, Inc. 07/24/172D 3D TSV
US9409858 37 Selective histone deactylase 6 inhibitors H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois 07/24/172D 3D TSV
US9408850 74 Substituted indazole derivatives active as kinase inhibitors NERVIANO MEDICAL SCIENCES S.R.L. 07/24/172D 3D TSV
US9403827 32 Substituted purinone compounds NOVARTIS AG 07/24/172D 3D TSV
US9403831 42 Triazolopyrazine derivative and use thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK INC. 07/24/172D 3D TSV
US9416103 25 Use of the aminoalkylindole JWH-073-M4 and related compounds as neutral CB1 receptor antagonists for the treatment of alcoholism, drug abuse, obesity, and obesity-related diseases The Board of Trustees of the University of Arkansas; The University of Kansas 07/24/172D 3D TSV
US9394275 191 Diamide compounds having muscarinic receptor antagonist and BETA2 adrenergic receptor agonist activity Theravance Respiratory Company, LLC 07/18/172D 3D TSV
US9394273 118 Therapeutic prostaglandin receptor agonists ALLERGAN, INC. 07/18/172D 3D TSV
US9403797 2 5-(pyridin-2-yl-amino)-pyrazine-2-carbonitrile compounds and their therapeutic use Cancer Research Technology Limited 07/17/172D 3D TSV
US9394291 20 Benzoxazinone amides as mineralocorticoid receptor modulators AstraZeneca AB 07/17/172D 3D TSV
US9403774 6 Guanidine and amine substituted tetrahydroisoquinoline compounds as factor xia inhibitors Bristol-Myers Squibb Company 07/17/172D 3D TSV
US9394285 186 Indole and indazole compounds that activate AMPK Pfizer Inc. 07/17/172D 3D TSV
US9394289 44 Inhibitors of c-fms kinase Janssen Pharmaceutica NV 07/17/172D 3D TSV
US9403804 10 Inhibitors of c-fms kinase Janssen Pharmaceutica NV 07/17/172D 3D TSV
US9388165 22 Isoquinoline-5-carboxamide derivative having inhibitory activity for protein kinase HANMI PHARM. CO., LTD. 07/17/172D 3D TSV
US9402837 20 Method for the treatment of neurological disorders by enhancing the activity of β-glucocerebrosidase Amicus Therapeutics, Inc. 07/17/172D 3D TSV
US9409887 14 Mutant-selective EGFR inhibitors and uses thereof Celgene Avilomics Research, Inc. 07/17/172D 3D TSV
US9388210 17 Neuroactive 17(20)-Z-vinylcyano-substituted steroids, prodrugs thereof, and methods of treatment using same WASHINGTON UNIVERSITY 07/17/172D 3D TSV
US9394282 406 Pyrazole carboxamides as Janus kinase inhibitors Merck Sharp & Dohme Corp. 07/17/172D 3D TSV
US9394290 90 Selective CYP11B1 inhibitors for the treatment of cortisol dependent diseases UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN 07/17/172D 3D TSV
US9394303 31 Small molecule inhibitors of MCL-1 and uses thereof THE REGENTS OF THE UNIVERSITY OF MICHIGAN 07/17/172D 3D TSV
US9393232 171 Substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-ones BeiGene, Ltd. 07/17/172D 3D TSV
US9394263 237 Substituted hetero-azepinones F. HOFFMANN-LA ROCHE AG 07/17/172D 3D TSV
US9394250 56 Substituted pyrrolidines as factor xia inhibitors for the treatment thromboembolic diseases ONO PHARMACEUTICAL CO., LTD. 07/17/172D 3D TSV
US9402842 12 Synthesis and use of dual tyrosyl-DNA phosphodiesterase I (Tdp1)—topoisomerase I (Top1) inhibitors Purdue Research Foundation 07/17/172D 3D TSV
US9394293 17 TRPV1 antagonists including dihydroxy substituent and uses thereof Purdue Pharma L.P. 07/17/172D 3D TSV
US9394254 6 Antibiotic and anti-parasitic agents that modulate class II fructose 1,6-bisphosphate aldolase The University of Denver and Regis University 07/10/172D 3D TSV
US9403822 5 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases ABBVIE INC. 07/10/172D 3D TSV
US9365589 82 C5, C6 oxacyclic-fused thiazine dioxide compounds as BACE inhibitors, compositions, and their use Merck Sharp & Dohme Corp. 07/10/172D 3D TSV
US9402878 2 Depsipeptide and uses thereof NovoBiotic Pharmaceuticals, LLC 07/10/172D 3D TSV
US9388139 97 Derivatives of celeboxib, use thereof and preparation thereof German University; Southern Research Institute 07/10/172D 3D TSV
US9388149 69 Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated diseases GALDERMA RESEARCH & DEVELOPMENT 07/10/172D 3D TSV
US9394307 6 Fused heteroaryl pyridyl and phenyl benzenesuflonamides as CCR2 modulators for the treatment of inflammation ChemoCentryx, Inc. 07/10/172D 3D TSV
US9388197 76 Heterocyclic amide derivatives as P2X7 receptor antagonists ACTELION PHARMACEUTICALS LTD. 07/10/172D 3D TSV
US9388198 17 Heterocyclic amide derivatives as P2X7 receptor antagonists ACTELION PHARMACEUTICALS LTD. 07/10/172D 3D TSV
US9394304 18 Imidazopyridine derivatives Hoffmann-La Roche Inc. 07/10/172D 3D TSV
US9365582 24 Macrocyclic inhibitors of hepatitis C virus Janssen Sciences Ireland UC 07/10/172D 3D TSV
US9388176 119 Method of treating conditiions with kinase inhibitors ALLERGAN, INC. 07/10/172D 3D TSV
US9365572 65 PI3K and/or mTOR inhibitor Xuanzhu Pharma Co., Ltd. 07/10/172D 3D TSV
US9403799 14 Pyrimidinyl-pyridazinone derivatives for treating a disease which is influenced by inhibition of met kinase MERCK PATENT GMBH 07/10/172D 3D TSV
US9388199 44 Pyrrolidine derivatives and their use as complement pathway modulators NOVARTIS AG 07/10/172D 3D TSV
US9388189 81 Pyrrolotriazinone derivatives as PI3K inhibitors Almirall, S.A. 07/10/172D 3D TSV
US9388171 28 Serine/threonine kinase inhibitors GENETECH, INC.; ARRAY BIOPHARMA INC. 07/10/172D 3D TSV
US9394276 16 Substituted 1,2,3,4-tetrahydro-2,6-naphthyridines as factor XIa inhibitors Bristol-Myers Squibb Company 07/10/172D 3D TSV
US9388181 15 Substituted 1,2,3,4-tetrahydropyrido[3,4-E] pyrrolo[1,2-A]pyrimidines as kinase Allergan, Inc. 07/10/172D 3D TSV
US9388140 120 Substituted benzimidazoles Bayer Intellectual Property GmbH 07/10/172D 3D TSV
US9388162 146 Substituted morphinans and the use thereof Purdue Pharma L.P. 07/10/172D 3D TSV
US9388136 35 Tert-butyl N-[2-{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]-3,5-difluorophenyl}ethyl]-L-alaninate or a salt, hydrate or solvate thereof Chroma Therapeutics Ltd 07/10/172D 3D TSV
USRE46024 22 Thyroid hormone analogs Hoffmann-La Roche Inc. 07/10/172D 3D TSV
US9365562 126 1,3 substituted azetidine PDE10 inhibitors Merck Sharp & Dohme Corp. 07/03/172D 3D TSV
US9364459 43 3-(indolyl)- or 3-(azaindolyl)- 4-arylmaleimide derivatives for use in the treatment of colon and gastric adenocarcinoma Johannes Gutenberg-Universität Mainz; Universitätsmedizin der Johannes Gutenberg-Universität Mainz 07/03/172D 3D TSV
US9365508 26 Aroyl thiourea derivatives University Court of the University of St Andrews; University Court of the University of Dundee 07/03/172D 3D TSV
US9365534 43 Arylated camphenes, processes for their preparation and uses thereof YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. 07/03/172D 3D TSV
US9365529 68 Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics GALDERMA RESEARCH & DEVLOPMENT 07/03/172D 3D TSV
US9359371 77 Bicyclic substituted pyrimidine compounds XUANZHU PHARMA CO., LTD. 07/03/172D 3D TSV
US9365511 26 Biphenyl-ethyl-pyrrolidine derivatives as histamine H3 receptor modulators for the treatment of cognitive disorders ARENA PHARMACEUTICALS, INC. 07/03/172D 3D TSV
US9359372 60 Hexahydrodibenzo[a,g]quinolizine compound, preparation method thereof, pharmaceutical composition and use thereof SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES 07/03/172D 3D TSV
US9359361 20 Immune system modulators JANUS BIOTHERAPEUTICS, INC. 07/03/172D 3D TSV
US9365575 25 Kinase inhibitors Allergan, Inc. 07/03/172D 3D TSV
US9365853 7 Matriptase inhibitors and uses thereof against orthomyxoviridae infections TBA 07/03/172D 3D TSV
US9365502 18 Neuroactive substituted cyclopenta[b]phenanthrenes as modulators for GABA type-A receptors WASHINGTON UNIVERSITY 07/03/172D 3D TSV
US9365539 11 Prolylcarboxypeptidase inhibitors Merck Sharp & Dohme Corp. 07/03/172D 3D TSV
US9365576 279 Pyrrolopyrrolidinone compounds Novartis AG 07/03/172D 3D TSV
US9388137 9 Quaternized amines as sodium channel blockers Purdue Pharma L.P. 07/03/172D 3D TSV
US9394283 2 Salt form of a human histone methyltransferase EZH2 inhibitor Epizyme, Inc.; Eisai R&D Management Co., LTD. 07/03/172D 3D TSV
US9364482 134 Substituted benzofuran compounds and methods of use thereof for the treatment of viral diseases Merck Sharp & Dohme Corp. 07/03/172D 3D TSV
US9394281 12 Substituted heteroaryl compounds and methods of use CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD. 07/03/172D 3D TSV
US9365546 8 Substituted pyridinone-pyridinyl compounds CONFLUENCE LIFE SCIENCES INC. 07/03/172D 3D TSV
US9359399 71 Synthetic peptide amides Cara Therapeutics, Inc. 07/03/172D 3D TSV
US9365563 228 TRPV1 antagonists including dihydroxy substituent and uses thereof Purdue Pharma L.P. 07/03/172D 3D TSV
US9359338 366 Cyclopropanecarboxamido-substitute aromatic compounds as anti-tumor agents CROWN BIOSCIENCE INC. (Taiwan) 06/27/172D 3D TSV
US9388160 4 Quinazoline derivatives as kinases inhibitors and methods of use thereof Teligene Ltd 06/27/172D 3D TSV
US9388170 7 Substituted aminoquinazolines useful as kinases inhibitors TBA 06/27/172D 3D TSV
US9353084 49 2-amino 3,5,5-trifluoro-3,4,5,6-tetrahydropyridines as BACE1 inhibitors for treatment of Alzheimer's disease H. Lundbeck A/S 06/26/172D 3D TSV
US9359337 12 Acetamide derivatives Hoffmann-La Roche Inc. 06/26/172D 3D TSV
US9359341 11 Aldehyde derivative of substitute oxazolidinones WANBURY LTD. 06/26/172D 3D TSV
US9353089 180 Compositions and methods for the treatment of malaria Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences 06/26/172D 3D TSV
US9353101 64 Cyclic amine substituted heterocyclic CETP inhibitors Merck Sharp & Dohme Corp. 06/26/172D 3D TSV
US9359348 11 Cyclopropyl imidazopyridine PDE10 inhibitors Merck Sharp & Dohme Corp. 06/26/172D 3D TSV
US9365558 99 Dihydropyridinone MGAT2 inhibitors Bristol-Myers Squibb Company 06/26/172D 3D TSV
US9359339 19 Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use Merck Sharp & Dohme Corp. 06/26/172D 3D TSV
US9353093 63 Indole-1-carboxamides as kinase inhibitors Allergan, Inc. 06/26/172D 3D TSV
US9353116 62 Methods and compositions for kinase inhibition The Regents of the University of California 06/26/172D 3D TSV
US9353102 88 Non-annulated thiophenylamides Hoffmann-La Roche Inc. 06/26/172D 3D TSV
US9353104 130 Substituted pyridizinone derivatives as PDE10 inhibitors Merck Sharp & Dohme Corp. 06/26/172D 3D TSV
US9359345 12 Thiazole derivatives as inhibitors of Bruton's tyrosine kinase HOFFMANN-LA ROCHE INC. 06/26/172D 3D TSV
US9393245 88 Tricyclic compounds as modulators of TNF-alpha synthesis and as PDE4 inhibitors vTv Therapeutics LLC 06/26/172D 3D TSV
US9353061 28 3,5,N-trihydroxy-alkanamide and derivatives: method for making same and use thereof ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY 06/19/172D 3D TSV
US9346829 31 5-HT3 receptor antagonists Takeda Phamaceutical Company Limited 06/19/172D 3D TSV
US9353081 132 Bicyclic dihydroquinoline-2-one derivatives Hoffmann-La Roche Inc. 06/19/172D 3D TSV
US9353075 66 Disubstituted beta-lactones as inhibitors of N-acylethanolamine acid amidase (NAAA) The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo” 06/19/172D 3D TSV
US9359301 14 Ethynyl derivatives Hoffmann-La Roche Inc. 06/19/172D 3D TSV
US9346814 250 FAP inhibitors Universiteit Antwerp; Fox Chase Cancer Center 06/19/172D 3D TSV
US9346821 66 Heterocyclic carboxylic acid ester derivative AJINOMOTO CO., INC. 06/19/172D 3D TSV
US9353090 331 Heterocyclic carboxylic acids as activators of soluble guanylate cyclase Boehringer Ingelheim International GmbH 06/19/172D 3D TSV
US9351965 152 Indazole derivatives useful as ERK inhibitors Merck Sharp & Dohme Corp. 06/19/172D 3D TSV
US9359293 24 Methods of treatment using modulators of SIRT2 CORNELL UNIVERSITY 06/19/172D 3D TSV
US9346786 123 Pyrrolidine compounds Hoffmann-La Roche Inc. 06/19/172D 3D TSV
US9353066 228 Substituted phenyl-Spleen Tyrosine Kinase (Syk) inhibitors Merck Sharp & Dohme Corp.; Merck Canada Inc. 06/19/172D 3D TSV
US9359330 25 Substituted piperidines as sodium channel blockers Purdue Pharma L.P. 06/19/172D 3D TSV
US9346815 934 5-chloro-2-difluoromethoxyphenyl pyrazolopyrimidine compounds, compositions and methods of use thereof Genentech, Inc. 06/12/172D 3D TSV
US9345742 42 Aminostatin derivatives for the treatment of arthrosis MERCK PATENT GMBH 06/12/172D 3D TSV
US9346770 29 Compounds having activating effect on subtypes of peroxisome proliferator-activated receptors and its preparation method and uses ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. 06/12/172D 3D TSV
US9353067 3 Heterocyclic compounds and uses thereof in the treatment of sexual disorders ATIR Holding S.A. 06/12/172D 3D TSV
US9353115 11 Immune system modulators JANUS BIOTHERAPEUTICS, INC. 06/12/172D 3D TSV
US9353083 4 Oxazetidine derivatives, process for preparing them and use in human medicine and in cosmetics GALDERMA RESEARCH & DEVELOPMENT 06/12/172D 3D TSV
US9358227 12 Pharmaceutical uses of 6-amino quinazoline or 3-cyano quinoline derivatives Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. 06/12/172D 3D TSV
US9346839 11 Phosphonate derivatives and methods of use thereof in the treatment of Alzheimer's disease University of Kansas 06/12/172D 3D TSV
US9351973 15 Pyrazolopyridyl compounds as aldosterone synthase inhibitors Merck Sharp & Dohme Corp. 06/12/172D 3D TSV
US9346794 85 Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity Boehringer Ingelheim International GmbH 06/12/172D 3D TSV
US9346795 186 Substituted sulfonamides useful as antiapoptotic Bcl inhibitors Bristol-Myers Squibb Company 06/12/172D 3D TSV
US9353113 13 Tetrahydrocarboline derivative ONO PHARMACEUTICAL CO., LTD. 06/12/172D 3D TSV
US9346827 11 5-amino-oxazepine and 5-amino-thiazepane compounds as beta secretase antagonists and methods of use Amgen Inc. 06/05/172D 3D TSV
US9346782 60 Alkyl linked quinolinyl modulators of RORγt Janssen Pharmaceutica NV 06/05/172D 3D TSV
US9346818 42 Benzodioxole derivative and preparation method and use thereof Zhejiang Hisun Pharmaceutical Co., Ltd. 06/05/172D 3D TSV
US9345700 53 Compositions and methods useful for treating diseases Eutropics Pharmaceuticals, Inc. 06/05/172D 3D TSV
US9346798 678 Dihydrobenzoxazine and tetrahydroquinoxaline sodium channel inhibitors AMGEN INC. 06/05/172D 3D TSV
US9346803 44 Indomethacin analogs for the treatment of castrate-resistant prostate cancer Vanderbilt University; The Trustees of the University of Pennsylvania 06/05/172D 3D TSV
US9340574 25 Inhibitors of protein tyrosine phosphatases Indiana University Research and Technology Corporation 06/05/172D 3D TSV
US9340549 193 Oxazolidinone compounds and derivatives thereof AMGEN INC. 06/05/172D 3D TSV
US9346787 28 Piperidine compound or salt thereof TAIHO PHARMACEUTICAL CO., LTD. 06/05/172D 3D TSV
US9339501 54 17a-hydroxylase/C17,20-lyase inhibitors NOVARTIS AG 05/31/172D 3D TSV
US9346797 14 2-amino 6-(difluoromethyl)-5,5-difluoro-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors H. Lundbeck A/S 05/31/172D 3D TSV
US9340500 154 Aromatic heterocyclic derivative having TRPV4-inhibiting activity SHIONOGI & CO., LTD. 05/31/172D 3D TSV
US9340537 173 Benzamide derivatives for inhibiting the activity of ABL1, ABL2 and BCR-ABL1 NOVATIS AG 05/31/172D 3D TSV
US9334269 337 Carboxamides as inhibitors of voltage-gated sodium channels AMGEN INC. 05/31/172D 3D TSV
US9346793 15 Hydroxylated aminotriazole derivatives as ALX receptor agonists Actelion Pharmaceuticals, LTD. 05/31/172D 3D TSV
US9340517 531 Methods of modulating the activity of the MC5 receptor and treatment of conditions related to this receptor Mimetica PTY LTD 05/31/172D 3D TSV
US9334286 108 Pharmacologically active compounds Cancer Research Technology Limited 05/31/172D 3D TSV
US9340530 84 Preparation and use of bicyclic himbacine derivatives as PAR-1 receptor antagonists Merck Sharp & Dohme Corp. 05/31/172D 3D TSV
US9340507 111 Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity Boehringer Ingelheim International GmbH 05/31/172D 3D TSV
US9353062 2 Substituted quinolines as bruton's tyrosine kinases inhibitors HangzhouDeRenYuCheng Biotechnology Ltd 05/31/172D 3D TSV
US9334290 152 Substituted tetrahydrocarbazole and carbazole carboxamide compounds Bristol-Myers Squibb Company 05/31/172D 3D TSV
US9340510 245 Tetrahydroisoquinoline derivatives, pharmaceutical compositions and uses thereof Boehringer Ingelheim International GmbH 05/31/172D 3D TSV
US9346822 4 Thienopyrimidine compounds and use thereof Takeda Pharmaceutical Company Limited 05/31/172D 3D TSV
US9340506 38 Acetamide derivatives as glucokinase activators, their process and medicinal applications ADVINUS THERAPEUTICS LIMITED 05/22/172D 3D TSV
US9340573 28 Azaindolines Hoffmann-La Roche Inc. 05/22/172D 3D TSV
US9340555 180 Compounds as tyrosine kinase modulators Allergan, Inc. 05/22/172D 3D TSV
US9345793 20 Compounds for binding to the platelet specific glycoprotein IIB/IIIA and their use for imaging of thrombi PIRAMAL IMAGING SA 05/22/172D 3D TSV
US9334279 129 Hepatitis C virus inhibitors Bristol-Myers Squibb Company 05/22/172D 3D TSV
US9345740 24 IAP antagonists Bristol-Myers Squibb Company 05/22/172D 3D TSV
US9340521 130 Method for dual inhibition of SGLT1 and SGLT2 using diphenylmethane derivatives GREEN CROSS CORPORATION 05/22/172D 3D TSV
US9340542 20 Propellane-based compounds and the use thereof Purdue Pharma L.P. 05/22/172D 3D TSV
US9340504 6 Pyridine and piperidine derivatives as novel sodium channel blockers Purdue Pharma L.P. 05/22/172D 3D TSV
US9346810 249 Pyrrolopyrimidine compounds and uses thereof HUTCHISON MEDIPHARMA LIMITED 05/22/172D 3D TSV
US9334288 34 Selective β-glucuronidase inhibitors as a treatment for side effects of camptothecin antineoplastic agents The University of North Carolina at Chapel Hill 05/22/172D 3D TSV
US9345789 13 Specific inhibitors and active site probes for legumain The Board of Trustees of the Leland Stanford Junior University 05/22/172D 3D TSV
US9328099 1336 Cyanomethylpyrazole carboxamides as janus kinase inhibitors Merck Sharp & Dohme Corp. 05/18/172D 3D TSV
US9333195 34 Quinuclidine derivatives and medicinal compositions containing the same ALMIRALL, S.A. 05/18/172D 3D TSV
US9334268 25 4-amino-imidazoquinoline compounds HOFFMAN-LA ROCHE INC. 05/15/172D 3D TSV
US9340534 4 Compounds and methods for treating ocular diseases ALLERGAN, INC. 05/15/172D 3D TSV
US9328106 297 Cyclic ether pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use GENENTECH, INC. 05/15/172D 3D TSV
US9339486 15 Heterocyclic modulators of cannabinoid receptors The Cleveland Clinic Foundation 05/15/172D 3D TSV
US9333217 10 Inhibitors of human EZH2, and methods of use thereof Epizyme, Inc. 05/15/172D 3D TSV
US9333205 6 Isoxazolo-quinazolines as modulators of protein kinase activity NERVIANO MEDICAL SCIENCES S.R.L. 05/15/172D 3D TSV
US9333199 13 Methods of treatment of histamine H-4 receptor-related pruritus associated with nerve disorders BRIDGE PHARMA, INC. 05/15/172D 3D TSV
US9340511 7 Process for making isoquinoline compounds FibroGen, Inc. 05/15/172D 3D TSV
US9334271 32 Purine derivatives and their use in the treatment of disease Novarits AG 05/15/172D 3D TSV
US9321790 119 Pyrimidinone derivatives as antimalarial agents Sanofi 05/15/172D 3D TSV
US9334278 38 Pyrrolo[2,3-B]pyrazines as SYK inhibitors Hoffmann-La Roche Inc. 05/15/172D 3D TSV
US9328096 800 Tropomyosin-related kinase inhibitors Pfizer Inc. 05/15/172D 3D TSV
US9328120 34 6-cycloalkyl-pyrazolopyrimidinones for the treatment of CNS disorders Boehringer Ingelheim International GmbH 05/08/172D 3D TSV
US9321791 46 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions Boehringer Ingelheim International GmbH 05/08/172D 3D TSV
US9326978 16 A3 adenosine receptor allosteric modulators The United States of America, Represented by the Secretary, Dept. of Health and Human Services; Universiteit Leiden 05/08/172D 3D TSV
US9321760 243 Aminopyrimidine derivatives for use as modulators of kinase activity Merck Patent GmbH 05/08/172D 3D TSV
US9333197 9 Apoptosis signal-regulating kinase inhibitor Gilead Sciences, Inc. 05/08/172D 3D TSV
US9321756 823 Azole compounds as PIM inhibitors AMGEN INC. 05/08/172D 3D TSV
US9328124 3 BACE inhibitors Eli Lilly and Company 05/08/172D 3D TSV
US9321773 21 Compounds Respivert, Ltd. 05/08/172D 3D TSV
US9328070 8 Ethynyl derivatives Hoffmann-La Roche Inc. 05/08/172D 3D TSV
US9328118 159 Nitrogen-containing bicyclic aromatic heterocyclic compound Astellas Pharma Inc. 05/08/172D 3D TSV
US9328123 5 Rotenone derivatives and a use thereof Korea Atomic Energy Research Institute 05/08/172D 3D TSV
US9328111 39 Substituted cycloocta[5,6]pyrido[4,3,2-de]phthalazines as PARP inhibitors BeiGene Ltd. 05/08/172D 3D TSV
US9328112 193 Tetracyclic CDK9 kinase inhibitors AbbVie Inc. 05/03/172D 3D TSV
US9315520 135 2-amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl-1,3-thiazol-4-yl amides Pfizer Inc. 05/01/172D 3D TSV
US9321748 59 Aminopyridine derived compounds as LRRK2 inhibitors H. Lundbeck A/S; Vernalis (R&D) Ltd. 05/01/172D 3D TSV
US9321728 33 Beta-alanine derivatives, pharmaceutically acceptable salts thereof, and pharmaceutical composition comprising same as active ingredient KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; HANDOK PHARMACEUTICALS CO., LTD. 05/01/172D 3D TSV
US9320741 14 Compositions and methods for treating neoplasia, inflammatory disease and other disorders DANA-FARBER CANCER INSTITUTE, INC. 05/01/172D 3D TSV
US9321743 25 Compositions and methods of inhibiting N-acylethanolamine-hydrolyzing acid amidase The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo” 05/01/172D 3D TSV
US9321766 10 Kinase inhibitors Allergan, Inc. 05/01/172D 3D TSV
US9321738 28 N-alkyltriazole compounds as LPAR antagonists HOFFMAN-LA ROCHE INC. 05/01/172D 3D TSV
US9321752 10 Pyrazole derivative GREEN TECH CO., LTD. 05/01/172D 3D TSV
US9321750 5 ROR modulators and their uses INNOV17 LLC 05/01/172D 3D TSV
US9320722 81 Regulators of aldehyde dehydrogenase ALDH3A1 and related therapeutic methods Indiana University Research and Technology Corporation 05/01/172D 3D TSV
US9320734 110 Small molecule inhibitors of the pleckstrin homology domain and methods for using same Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona 05/01/172D 3D TSV
US20160326143 65 Compounds and uses Astrazeneca Ab 04/27/172D 3D TSV
US9320732 21 1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase Incyte Corporation; Incyte Holdings Corporation 04/24/172D 3D TSV
US9315514 32 1,3-dioxanomorphides and 1,3-dioxanocodides Rhodes Technologies 04/24/172D 3D TSV
US9321747 21 Acid addition salt of substituted pyridine compound DAIICHI SANKYO COMPANY, LIMITED; UBE INDUSTRIES, LTD. 04/24/172D 3D TSV
US9315498 174 Arlethynyl derivatives HOFFMAN-LA ROCHE INC. 04/24/172D 3D TSV
US9315500 26 Bicyclic heteroaryl cycloalkyldiamine derivatives NOVARTIS AG 04/24/172D 3D TSV
US9315489 98 Compounds and compositions for inhibiting the activity of ABL1, ABL2 and BCR-ABL1 Novartis AG 04/24/172D 3D TSV
US9315499 41 Cytomegalovirus inhibitor compounds Boehringer Ingelheim International GmbH 04/24/172D 3D TSV
US9315519 6 Guanidine substituted tetrahydroisoquinoline compounds as factor XIa inhibitors Bristol-Myers Squibb Company 04/24/172D 3D TSV
US9315518 40 Imidazopyridin-2-one derivatives Merck Sharp & Dohme Corp. 04/24/172D 3D TSV
US9321721 8 Kinase inhibitors Allergan, Inc. 04/24/172D 3D TSV
US9315493 18 Phenylpyridine derivative and drug containing same KOWA COMPANY, LTD. 04/24/172D 3D TSV
US9315491 129 Pyrimidine compounds as mTOR and PI3K inhibitors DEVELOPMENT CENTER FOR BIOTECHNOLOGY; DCB-USA LLC 04/24/172D 3D TSV
US9320737 32 Substituted imidazopyridazines BAYER INTELLECTUAL PROPERTY GMBH 04/24/172D 3D TSV
US9315508 3 Treating diabetes with dipeptidyl peptidase-IV inhibitors Merck sharp & Dohme Corp. 04/24/172D 3D TSV
US9303017 131 2,5-disubstituted-pyridyl nicotinic ligands, and methods of use thereof Georgetown University; Duke University 04/10/172D 3D TSV
US9303045 162 5-HT3 receptor antagonists Takeda Pharmaceutical Company Limited 04/10/172D 3D TSV
US9303025 407 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases AbbVie Inc. 04/10/172D 3D TSV
US9314468 140 Chemokine receptor modulators Altiris Therapeutics, Inc. 04/10/172D 3D TSV
US9314464 22 Compounds and compositions as protein kinase inhibitors Novartis AG 04/10/172D 3D TSV
US9315463 30 Cyclohexylamine derivatives having β2 adrenergic agonist and M3 muscarinic antagonist activities Almirall, S.A. 04/10/172D 3D TSV