BDBM12014 2-fluoro-SBB::4-(AMINOSULFONYL)-N-[(2-FLUOROPHENYL)METHYL]-BENZAMIDE::N-[(2-fluorophenyl)methyl]-4-sulfamoylbenzamide

SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCc1ccccc1F


Data  1 Kd

PDB links: 2 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12014   

TargetCarbonic anhydrase 2 [F130V](Homo sapiens (Human))
University of Pennsylvania

LigandPNGBDBM12014(2-fluoro-SBB | 4-(AMINOSULFONYL)-N-[(2-FLUOROPHENY...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NCc1ccccc1F
Show InChI InChI=1S/C14H13FN2O3S/c15-13-4-2-1-3-11(13)9-17-14(18)10-5-7-12(8-6-10)21(16,19)20/h1-8H,9H2,(H,17,18)(H2,16,19,20)
Affinity DataKd:  2.30nMpH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair