BDBM150162 BI-10773::Jardiance::US8980829, EMPAGLIFLOZIN::empagliflozin

SMILES: c1cc(ccc1Cc2cc(ccc2Cl)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O[C@H]4CCOC4

InChI Key: InChIKey=OBWASQILIWPZMG-UHFFFAOYSA-N

Data: 5 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 150162   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Human)	BDBM150162 (US8980829, EMPAGLIFLOZIN | empagliflozin | BI-1077...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM150162 (US8980829, EMPAGLIFLOZIN | empagliflozin | BI-1077...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.24E+3	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM150162 (US8980829, EMPAGLIFLOZIN | empagliflozin | BI-1077...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM150162 (US8980829, EMPAGLIFLOZIN | empagliflozin | BI-1077...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM150162 (US8980829, EMPAGLIFLOZIN | empagliflozin | BI-1077...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM150162 (US8980829, EMPAGLIFLOZIN | empagliflozin | BI-1077...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM150162 (US8980829, EMPAGLIFLOZIN | empagliflozin | BI-1077...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM150162 (US8980829, EMPAGLIFLOZIN | empagliflozin | BI-1077...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair